The DOI matches its Crossref record.
Genetics versus environment in inflammatory bowel disease: results of a British twin study
Open accessAbstract
Outcome of antenatal Down's syndrome screening.Values are numbers (percentages; 95% confidence intervals) unless otherwise indicated All women White and other Indian Asians Total eligible for screening 9217 7562 1655 Uptake of serum screening 7953 (86.3) 6765 (89-5) 1188 (71-8) Women screened positive 382 (4-8) 236 (3-5) 146 (12-3) Relative risk 3.5 (2-9 to 4-3) Amniocentesis uptake 179 (48) 142 (60) 37 (27) X12 43-9 (P<0.001)Detection rate for Down's syndrome 5/14 (36) 5/12 0/2 (42; 13 to 72) (0; to 84) Positive predictive value 1:76 (5/382) 1:47 0:146 No of cases of Down's syndrome: Identified antenatally 6* 6* 0 Identified postnatally 12t 9t 3t Rate per 1000 births 1.8* 1.8* 1.8 *Includes one case of Down's syndrome identified by primary amniocentesis; details available from the authors on request.tlncludes the Down's syndrome births missed by serum screening and those occurring in unscreened women.*After a 23% reduction in antenatally diagnosed and terminated cases to allow for the increased fetal death rate in pregnancies with Down's syndrome diagnosed by amniocentesis but not ending in a termination.'
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Cited by
Inflammatory bowel disease: cause and immunobiology
Baumgart, D. C., & Carding, S. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60750-8 · Cited by 2,147
Rioux, J. D., Xavier, R. J., Taylor, K. D., Silverberg, M. S., Goyette, P., Huett, A., Green, T., Kuballa, P., Barmada, M. M., Datta, L. W., et al. (2007) · Nature Genetics · doi:10.1038/ng2032 · Cited by 1,769
The immunological and genetic basis of inflammatory bowel disease
Bouma, G., & Strober, W. (2003) · Nature Reviews Immunology · doi:10.1038/nri1132 · Cited by 1,767
Epidemiology and risk factors for IBD
Ananthakrishnan, A. N. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.34 · Cited by 1,741
The genetics and immunopathogenesis of inflammatory bowel disease
Cho, J. H. (2008) · Nature Reviews Immunology · doi:10.1038/nri2340 · Cited by 940
Metadata
- Authors
- Thompson, N. P., Driscoll, R., Pounder, R. E., & Wakefield, A. J.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1996-01-13
- Volume
- 312
- Issue
- 7023
- Pages
- 95-96
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2031035500
- Cited by
- 336
- References
- 0
- FWCI
- 5.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Thompson, N. P., Driscoll, R., Pounder, R. E., & Wakefield, A. J. (1996). Genetics versus environment in inflammatory bowel disease: results of a British twin study. BMJ. https://doi.org/10.1136/bmj.312.7023.95
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