The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Randomised controlled trial of efficacy of teaching patients with bipolar disorder to identify early symptoms of relapse and obtain treatment
Open accessAbstract
OBJECTIVE: To determine the efficacy of teaching patients with bipolar disorder (manic-depressive psychosis) to identify early symptoms of relapse and seek prompt treatment from health services. DESIGN: Single blind randomised controlled trial with matching on four baseline variables using a minimisation algorithm. SETTING: Mental health services in four NHS trusts (one teaching, three non-teaching). SUBJECTS: 69 patients with bipolar disorder who had had a relapse in the previous 12 months. INTERVENTIONS: Seven to 12 individual treatment sessions from a research psychologist plus routine care or routine care alone. MAIN OUTCOME MEASURES: Time to first manic or depressive relapse, number of manic or depressive relapses, and social functioning examined by standardised interviews every six months for 18 months. RESULTS: 25th centile time to first manic relapse in experimental group was 65 weeks compared with 17 weeks in the control group. Event curves of time to first manic relapse significantly differed between experimental and control groups (log rank 7.04, df=1, P=0.008), with significant reductions in the number of manic relapses over 18 months (median difference 30% (95% confidence interval 8% to 52%), P=0.013). The experimental treatment had no effect on time to first relapse or number of relapses with depression, but it significantly improved overall social functioning (mean difference 2.0 (0.7 to 3.2), P=0.003) and employment (mean difference 0.7 (0.1 to 1.3), P=0.030) by 18 months. CONCLUSION: Teaching patients to recognise early symptoms of manic relapse and seek early treatment is associated with important clinical improvements in time to first manic relapse, social functioning, and employment.
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Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised
Kobylski, T. P. (1988) · Psychosomatics · doi:10.1016/s0033-3182(88)72438-x · Cited by 1,054
Relapse and impairment in bipolar disorder
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Family Factors and the Course of Bipolar Affective Disorder
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Outcome in Mania: A 4-Year Prospective Follow-up of 75 Patients Utilizing Survival Analysis
Tohen, M. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810240026005 · Cited by 532
Teixeira, J. M. A., Fisk, N. M., & Glover, V. (1999) · BMJ · doi:10.1136/bmj.318.7177.153 · Cited by 526
Keck, P. E., McElroy, S. L., Strakowski, S. M., West, S. A., Sax, K. W., Hawkins, J. M., Bourne, M. L., & Haggard, P. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.5.646 · Cited by 455
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Self-citationOutcome in Manic Disorders: A Naturalistic Follow-up Study
Harrow, M. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810190065009 · Cited by 346
Maj, M., Pirozzi, R., Magliano, L., & Bartoli, L. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.1.30 · Cited by 242
Recurrence in affective disorder: I. Case register study
Kessing, L. V., Bolwig, T. G., Andersen, P. K., & Mortensen, P. B. (1998) · British Journal of Psychiatry · doi:10.1192/bjp.172.1.23 · Cited by 214
Cited by
Goodwin, G., Haddad, P., Ferrier, I., Aronson, J., Barnes, T., Cipriani, A., Coghill, D., Fazel, S., Geddes, Jr., Grunze, H., et al. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116636545 · Cited by 1,309
Self-citationMalhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842
“In this context, early warning signs that indicate a manic episode is imminent can be used to facilitate an early admission to hospital so as to modify management and curtail the development of a full-blown manic episode (Perry et al., 1999), though this is not always effective (Lobban et al.”
BackgroundGeddes, J. R., & Miklowitz, D. J. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60857-0 · Cited by 848
Two-Year Outcomes for Interpersonal and Social Rhythm Therapy in Individuals With Bipolar I Disorder
Frank, E., Kupfer, D. J., Thase, M. E., Mallinger, A. G., Swartz, H. A., Fagiolini, A. M., Grochocinski, V., Houck, P., Scott, J., Thompson, W., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.9.996 · Cited by 770
Practice Guideline for the Treatment of Patients With Bipolar Disorder (Revision)
Hirschfeld, R. M. A., Bowden, C. L., Gitlin, M. J., Keck, P. E., Perlis, R. H., Suppes, T., Thase, M. E., & Wagner, K. D. (2003) · Focus · doi:10.1176/foc.1.1.64 · Cited by 585
Metadata
- Authors
- Perry, A., Tarrier, N., Morriss, R., McCarthy, E., & Limb, K.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1999-01-16
- Volume
- 318
- Issue
- 7177
- Pages
- 149-153
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2141144319
- Cited by
- 586
- References
- 23
- FWCI
- 8.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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