Cited by 159Meta-analysis and systematic reviewsClinical practice guidelines implementationDelphi Technique in Research

Quality of Cochrane reviews: Assessment of sample from 1998.

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Olsen, Ole, Middleton, Philippa, Ezzo, Jeanette, Gøtzsche, Peter C, Hadhazy, Victoria, Herxheimer, Andrew, Kleijnen, Jos, McIntosh, Heather·2001·BMJ

Abstract

Abstract Objective: To assess the quality of Cochrane reviews. Design: Ten methodologists affiliated with the Cochrane Collaboration independently examined, in a semistructured way, the quality of reviews first published in 1998. Each review was assessed by two people; if one of them noted any major problems, they agreed on a common assessment. Predominant types of problem were categorised. Setting: Cyberspace collaboration coordinated from the Nordic Cochrane Centre. Studies: All 53 reviews first published in issue 4 of the Cochrane Library in 1998. Main outcome measure: Proportion of reviews with various types of major problem. Results: No problems or only minor ones were found in most reviews. Major problems were identified in 15 reviews (29%). The evidence did not fully support the conclusion in nine reviews (17%), the conduct or reporting was unsatisfactory in 12 reviews (23%), and stylistic problems were identified in 12 reviews (23%). The problematic conclusions all gave too favourable a picture of the experimental intervention. Conclusions: Cochrane reviews have previously been shown to be of higher quality and less biased on average than other systematic reviews, but improvement is always possible. The Cochrane Collaboration has taken steps to improve editorial processes and the quality of its reviews. Meanwhile, the Cochrane Library remains a key source of evidence about the effects of healthcare interventions. Its users should interpret reviews cautiously, particularly those with conclusions favouring experimental interventions and those with many typographical errors. What is already known on this topic Cochrane reviews are, on average, more systematic and less biased than systematic reviews published in paper journals Errors and biases also occur in Cochrane reviews What this study adds Too often, reviewers' conclusions over-rated the benefits of new interventions Readers of Cochrane reviews should remain cautious, especially regarding conclusions that favour new interventions The Cochrane Collaboration has taken steps to improve the quality of reviews

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Research works printed but not linked: 5

  1. Yusuf S, Simon R, Ellenberg S, eds. Proceedings of "Methodologic issues in overviews of randomized clinical trials." Stat Med 1987;6:217-409.
  2. Oxman AD. Checklists for review articles. BMJ 1994;309:648-51.
  3. Jadad AR, Cook DJ, Jones A, Klassen TP, Tugwell P, Moher M. Methodology and reports of systematic reviews and meta-analyses. JAMA 1998;280:278-80.
  4. Shea B, Dubé C, Moher D. Assessing the quality of reports of systematic reviews and meta-analyses: A systematic review of checklists and scales [abstract]. VII Cochrane Colloquium, Rome, 5-9 October 1999:A40.
  5. Clarke M, Oxman AD, eds. Common errors in reaching conclusions. Cochrane reviewers' handbook 4.1.3, section 9.7. In: Cochrane Library. Issue 3. Oxford: Update Software, 2001.

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Authors
Olsen, O., Middleton, P., Ezzo, J., Gøtzsche, P. C., Hadhazy, V., Herxheimer, A., Kleijnen, J., & McIntosh, H.
Affiliations
  • Rigshospitalet (DK)
  • Flinders Medical Centre (AU)
  • University of Maryland, Baltimore (US)
  • Cochrane (GB)
  • University of York (GB)
Corresponding author
Olsen, Ole
Venue
BMJ
Publisher
BMJ
Published
2001-10-13
Volume
323
Issue
7317
Pages
829-832
ISSN
  • 0007-1447 (ISSN-L)
  • 0959-8138
  • 1468-5833
OpenAlex
W2154762721
Cited by
159
References
20
Citations by year
2025: 2 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 1 · 2017: 6 · 2016: 2 · 2015: 6 · 2014: 10 · 2013: 13 · 2012: 6
FWCI
17.73
Type
journal article
Language
en
Open access
Locations
  • BMJ (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (submittedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
  • DigitalGeorgetown (Georgetown University Library) (submittedVersion)
Topics
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
  • Social Sciences › Sociology and Political Science › Delphi Technique in Research
Keywords
review quality, systematic review methodology, reporting quality, editorial quality, Cochrane Library, health interventions
MeSH terms
Humans, Review Literature as Topic, Meta-Analysis as Topic, Bias, Evidence-Based Medicine, Databases as Topic

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