The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Diagnosis and management of motor neurone disease
Open accessAbstract
Motor neurone disease is a devastating illness which leads to progressive paralysis and eventual death. We will discuss the presentation of motor neurone disease in primary care and update non-specialists on progress with regards to life prolonging interventions, better control of disease symptoms, and an increased understanding of disease mechanisms. Motor neurone disease is rare but patients often are aware of it, so this review should help non-specialists reassure patients in whom it is unlikely to be the diagnosis.
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“Approximately 20% of plwALS experience initial changes in the brainstem (bulbar) region of the brain, resulting in dysarthria (McDermott and Shaw, 2008).”
From Dysarthria and other-initiated repair in everyday conversation (2020) · cites this paper as McDermott and Shaw, 2008
Citations
Cites
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Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C., Micsenyi, M. C., Chou, T. T., Bruce, J., Schuck, T., Grossman, M., Clark, C. M., et al. (2006) · Science · doi:10.1126/science.1134108 · Cited by 6,576
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
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Dose-ranging study of riluzole in amyotrophic lateral sclerosis
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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
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Bourke, S. C., Tomlinson, M., Williams, T. L., Bullock, R., Shaw, P. J., & Gibson, G. J. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70326-4 · Cited by 1,170
Self-citationRiluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
Miller, R. G., Mitchell, J. D., & Moore, D. H. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001447.pub3 · Cited by 1,123
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
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Traynor, B. J. (2003) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.9.1258 · Cited by 493
Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target
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Items 201–221 of 221
Hughes, J. C., & Lilford, P. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108594714.029
Roscoe, S., Skinner, E., Kibirige, E. K., Childs, C., Weekes, C. E., Wootton, S. A., Allen, S. P., McDermott, C. J., & Stavroulakis, T. (2022) · medRxiv · doi:10.1101/2022.12.19.22283673
Self-citationManagement of motor neuron disease with updated therapies: A review
Kumar, R., Kumar, G., Saini, K., & Jha, S. (2023) · IP Indian Journal of Neurosciences · doi:10.18231/j.ijn.2023.001
Clinical Profile of Various Mnd Cases that Presented to a Tertiary Centre over the Past 3 Years
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CHRONIC CONSTIPATION AND DEFECATION DISORDERS IN A NEUROLOGICAL PATIENT WITH LIMITED MOBILITY
Фирсова, Л. А., Novikova, V. P., Завьялова, А. Н., & Балашов, А. Л. (2023) · Children s medicine of the North-West · doi:10.56871/cmn-w.2023.72.34.003
Amyotrophic Lateral Sclerosis – A Comprehensive Review
Jayavasavi., K., & Kumar, S. S. (2023) · International Journal of Membrane Science and Technology · doi:10.15379/ijmst.v10i5.3569
Douglas, K., & Burman, R. (2024) · doi:10.1093/med/9780192864741.003.0030
Galeazzi, L., Holzman, J., Porporatti, A. L., & Rochefort, J. (2024) · Cureus · doi:10.7759/cureus.64153
Puri, S. N., Raghuveer, R., Jachak, S., & Tikhile, P. (2024) · Cureus · doi:10.7759/cureus.68373
Bamber, R. W., Carlton, J., McDermott, C. J., & Stavroulakis, T. (2025) · Health and Quality of Life Outcomes · doi:10.1186/s12955-025-02427-2 · Cited by 1
Self-citationPollock, D., Stern, C., Bond, M., Barker, T. H., Hasanoff, S., McBride, G. M., Semendric, I., Fragkoudi, A., Shrestha, N., Facchin‐Young, S. C., et al. (2026) · Clinical and Public Health Guidelines · doi:10.1002/gin2.70062
Brannigan, J., Cave, R., Horsfall, H. L., Akram, H., Schaefer, A. T., Marcus, H. J., Bashford, L., & Muirhead, W. R. (2025) · JMIR Neurotechnology · doi:10.2196/82142
Mohamed, L. A. A. H., Shalaby, M. F., Williamson, R., McLean, S. L., & Kantamneni, S. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.01.735805
Etemadifar, M., Salari, M., Kashefi, M., Shams, Y., Sichani, M. H., & Hojjatipour, F. (2026) · Neurodegenerative Disease Management · doi:10.1080/17582024.2026.2718409
Ahmad, R., Naeem, M., & Houlden, H. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12618-9
Pollock, D., Shrestha, N., Facchin‐Young, S. C., Fragkoudi, A., Day‐Sharman, A. M., Bulto, L. N., Bond, M., Stern, C., Barker, T. H., Hasanoff, S., et al. (2026) · Neurodegenerative Disease Management · doi:10.1080/17582024.2026.2749397
Cervical Assistive Technologies: A Multidimensional Review of Neck Exoskeletons
Poblete, S., Palacios-Davalos, F., Bolanos-Aedo, R., Ponce-Bohórquez, A., Vallejo-Escriba, B., Soncco, F., Valcarcel-Castillo, H., Calderon-Mendez, P., & Huamanchahua, D. (2025) · IEEE Baja California Conference (BCC) · doi:10.1109/bcc63751.2025.11725787
Metadata
- Authors
- McDermott, C. J., & Shaw, P. J.
- Affiliations
- University of Sheffield (GB)
- Corresponding author
- McDermott, Christopher J
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2008-03-20
- Volume
- 336
- Issue
- 7645
- Pages
- 658-662
- ISSN
- 1756-1833 (ISSN-L)
- 0959-8138
- PMC
- PMC2270983
- OpenAlex
- W1993915028
- Cited by
- 220
- References
- 28
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 12 · 2023: 11 · 2022: 14 · 2021: 11 · 2020: 35 · 2019: 14 · 2018: 8 · 2017: 15 · 2016: 11 · 2015: 16 · 2014: 9 · 2013: 12 · 2012: 9
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- BMJ (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
- Health Sciences › Medicine › Genetics (clinical) › Neurogenetic and Muscular Disorders Research
- Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
- Keywords
- motor neuron disease, diagnosis, management, primary care, symptom management, disease mechanisms, progressive paralysis, patient reassurance
- MeSH terms
- Antioxidants, Diagnosis, Differential, Humans, Physician-Patient Relations, Respiratory Therapy, Motor Neuron Disease, Neuroprotective Agents, Riluzole
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