Cited by 221Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders ResearchPeripheral Neuropathies and Disorders

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Diagnosis and management of motor neurone disease

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McDermott, Christopher J, Shaw, Pamela J·2008·BMJ

DOI 10.1136/bmj.39493.511759.bePMC PMC2270983

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Abstract

Motor neurone disease is a devastating illness which leads to progressive paralysis and eventual death. We will discuss the presentation of motor neurone disease in primary care and update non-specialists on progress with regards to life prolonging interventions, better control of disease symptoms, and an increased understanding of disease mechanisms. Motor neurone disease is rare but patients often are aware of it, so this review should help non-specialists reassure patients in whom it is unlikely to be the diagnosis.

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Authors: McDermott, C. J., & Shaw, P. J.
Affiliations: University of Sheffield (GB)
Corresponding author: McDermott, Christopher J
ORCID: McDermott, Christopher J
Shaw, Pamela J
Venue: BMJ
Publisher: BMJ
Published: 2008-03-20
Volume: 336
Issue: 7645
Pages: 658-662
ISSN: 1756-1833 (ISSN-L)
0959-8138
DOI: 10.1136/bmj.39493.511759.be
PMC: PMC2270983
OpenAlex: W1993915028
Cited by: 220
References: 28
Citations by year: 2026: 8 · 2025: 12 · 2024: 12 · 2023: 11 · 2022: 14 · 2021: 11 · 2020: 35 · 2019: 14 · 2018: 8 · 2017: 15 · 2016: 11 · 2015: 16 · 2014: 9 · 2013: 12 · 2012: 9
FWCI: 4.92
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.bmj.org/licenses/tdm/1.0/terms-and-conditions.html (tdm)
Locations: BMJ (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
Health Sciences › Medicine › Genetics (clinical) › Neurogenetic and Muscular Disorders Research
Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
Keywords: motor neuron disease, diagnosis, management, primary care, symptom management, disease mechanisms, progressive paralysis, patient reassurance
MeSH terms: Antioxidants, Diagnosis, Differential, Humans, Physician-Patient Relations, Respiratory Therapy, Motor Neuron Disease, Neuroprotective Agents, Riluzole

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