Diagnosis and management of motor neurone disease

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, E., Mengoni, I., Caprini, M., Peña‐Altamira, E., Kurtys, E., & Monti, B. (2012) · Neurosignals · doi:10.1159/000337115 · Cited by 9,023

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C., Micsenyi, M. C., Chou, T. T., Bruce, J., Schuck, T., Grossman, M., Clark, C. M., et al. (2006) · Science · doi:10.1126/science.1134108 · Cited by 6,576

Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

Boillée, S., Yamanaka, K., Lobsiger, C. S., Copeland, N. G., Jenkins, N. A., Kassiotis, G., Kollias, G., & Cleveland, D. W. (2006) · Science · doi:10.1126/science.1123511 · Cited by 1,623

Dose-ranging study of riluzole in amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis/Riluzole Study Group II, Lacomblez, L., Bensimon, G., Meininger, V., Leigh, P. N., & Guillet, P. (1996) · The Lancet · doi:10.1016/s0140-6736(96)91680-3 · Cited by 1,303

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Nagai, M., Re, D. B., Nagata, T., Chalazonitis, A., Jessell, T. M., Wichterle, H., & Przedborski, S. (2007) · Nature Neuroscience · doi:10.1038/nn1876 · Cited by 1,220

Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial

Bourke, S. C., Tomlinson, M., Williams, T. L., Bullock, R., Shaw, P. J., & Gibson, G. J. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70326-4 · Cited by 1,170

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

Miller, R. G., Mitchell, J. D., & Moore, D. H. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001447.pub3 · Cited by 1,123

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)

Miller, R. G., Jd, M., Lyon, M., & Moore, D. (2002) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001447 · Cited by 910

Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996-2000

Traynor, B. J. (2003) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.9.1258 · Cited by 493

Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target

Barber, S. C., Mead, R. J., & Shaw, P. J. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2006.03.008 · Cited by 489

Nutritional status is a prognostic factor for survival in ALS patients

Desport, J. C., Preux, P., Truong, T., Vallat, J. M., Sautereau, D., & Couratier, P. (1999) · Neurology · doi:10.1212/wnl.53.5.1059 · Cited by 486

Nutritional status of patients with amyotrophic lateral sclerosis: relation to the proximity of death

Kasarskis, E. J., Berryman, S., Vanderleest, J. G., Schneider, A., & McClain, C. J. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.1.130 · Cited by 293

EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives

Andersen, P. M., Borasio, G. D., Dengler, R., Hardiman, O. M., Kollewe, K., Leigh, P. N., Pradat, P., Silani, V., & Tomik, B. (2005) · European Journal of Neurology · doi:10.1111/j.1468-1331.2005.01351.x · Cited by 290

The epidemiology of motor neuron diseases: a review of recent studies

Worms, P. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(01)00630-x · Cited by 278

Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

Jiang, Y., Yamamoto, M., Kobayashi, Y., Yoshihara, T., Liang, Y., Terao, S., Takeuchi, H., Ishigaki, S., Katsuno, M., Adachi, H., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20379 · Cited by 255

Whole-Genome Analysis of Sporadic Amyotrophic Lateral Sclerosis

Dunckley, T., Huentelman, M. J., Craig, D. W., Pearson, J. V., Szelinger, S., Joshipura, K., Halperin, R. F., Stamper, C., Jensen, K. R., Letizia, D., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa070174 · Cited by 236

Stem cell treatment in Amyotrophic Lateral Sclerosis

Mazzini, L., Mareschi, K., Ferrero, I., Vassallo, E., Oliveri, G., Nasuelli, N. A., Oggioni, G. D., Testa, L., & Fagioli, F. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.05.016 · Cited by 227

Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data

Schymick, J. C., Scholz, S. W., Fung, H., Britton, A. F., Arepalli, S., Gibbs, J. R., Lombardo, F., Matarín, M., Kasperavičiūtė, D., Hernandez, D. G., et al. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70037-6 · Cited by 218

Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

Ferraiuolo, L., Heath, P. R., Holden, H. M., Kasher, P. R., Kirby, J., & Shaw, P. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1470-07.2007 · Cited by 198

Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004

O'Toole, O., Traynor, B. J., Brennan, P., Sheehan, C., Frost, E., Corr, B., & Hardiman, O. (2008) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.117788 · Cited by 197

Motor neurone disease: a hospice perspective.

O’Brien, T., Kelly, M. J., & Saunders, C. (1992) · BMJ · doi:10.1136/bmj.304.6825.471 · Cited by 175

Amyotrophic Lateral Sclerosis: Enteral Nutrition Provision—Endoscopic or Radiologic Gastrostomy?

Thornton, F. J., Fotheringham, T., Alexander, M. D., Hardiman, O. M., McGrath, F. P., & Lee, M. J. (2002) · Radiology · doi:10.1148/radiol.2243010909 · Cited by 130

The Scottish Motor Neuron Disease Register: a prospective study of adult onset motor neuron disease in Scotland. Methodology, demography and clinical features of incident cases in 1989.

(1992) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.55.7.536 · Cited by 121

Antioxidant treatment for amyotrophic lateral sclerosis or motor neuron disease

Orrell, R. W., Lane, R. J., & Ross, M. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002829.pub4 · Cited by 98

Breaking the news in amyotrophic lateral sclerosis

Borasio, G. D. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00211-1 · Cited by 92

Motor neuron disorders

Shaw, P. J., & Strong, M. J. (2003) · Cited by 51

ALS: life and death in a bad neighborhood

Monk, P. N., & Shaw, P. J. (2006) · Nature Medicine · doi:10.1038/nm0806-885 · Cited by 45

Chapter 4 Molecular mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis

Barber, S. C., & Shaw, P. J. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)80007-8 · Cited by 3

Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia‐response and RNA processing functions

Raman, R., Allen, S. P., Goodall, G., Kramer, S., Ponger, L., Heath, P. R., Milo, M., Hollinger, H. C., Walsh, T., Highley, J. R., et al. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12147 · Cited by 254

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

Goodall, E. F., Heath, P. R., Bandmann, O., Kirby, J., & Shaw, P. J. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00178 · Cited by 187

Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study

ProGas Study Group (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00104-0 · Cited by 165

The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype

Cooper‐Knock, J., Shaw, P. J., & Kirby, J. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1251-9 · Cited by 169

A 10-year literature review of family caregiving for motor neurone disease: Moving from caregiver burden studies to palliative care interventions

Aoun, S. M., Bentley, B., Funk, L., Toye, C., Grande, G., & Stajduhar, K. J. (2013) · Palliative Medicine · doi:10.1177/0269216312455729 · Cited by 152

Motor neurone disease - caring for the patient in general practice.

Zoing, M. C., & Kiernan, M. C. (2011) · PubMed

Motor neurone disease.

Gm, C. (1989) · PubMed · Cited by 2

Motor neurone disease: an overview

Marsden, R. (2011) · Primary Health Care · doi:10.7748/phc2011.12.21.10.31.c8851 · Cited by 3

Clinical aspects of motor neurone disease

Moore, C., McDermott, C. J., & Shaw, P. J. (2008) · Medicine · doi:10.1016/j.mpmed.2008.09.001 · Cited by 5

Motor Neuron Disease: Pathophysiology, Diagnosis, and Management

Foster, L. A., & Salajegheh, M. K. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.07.012 · Cited by 119