Achieving large-scale clinician adoption of AI-enabled decision support
Open accessAbstract
Computerised decision support (CDS) tools enabled by artificial intelligence (AI) seek to enhance accuracy and efficiency of clinician decision-making at the point of care. Statistical models developed using machine learning (ML) underpin most current tools. However, despite thousands of models and hundreds of regulator-approved tools internationally, large-scale uptake into routine clinical practice has proved elusive. While underdeveloped system readiness and investment in AI/ML within Australia and perhaps other countries are impediments, clinician ambivalence towards adopting these tools at scale could be a major inhibitor. We propose a set of principles and several strategic enablers for obtaining broad clinician acceptance of AI/ML-enabled CDS tools.
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AI systems initially intended to lower healthcare costs often end up requiring substantial human oversight.
“AI systems initially intended to lower healthcare costs often end up requiring substantial human oversight, illustrating the complexities involved in integrating AI effectively into clinical workflows without sacrificing clinician autonomy or patient safety [9,10].”
From Enhancing Clinician Trust in AI Diagnostics: A Dynamic Framework for Confidence Calibration and Transparency (2025) · cites this paper as [10]
In “The tool must not incur excessive opportunity cost or environmental impacts” (page unavailable), the paper describes costs for clinician involvement and ongoing maintenance. Its governance section also calls for ongoing monitoring and auditing. It does not say that AI systems are initially intended to lower healthcare costs or that they often end up requiring substantial human oversight. (LLM, conf=0.82)
Experimental — accuracy not yet measuredMixed-method evaluations show that clinicians are more confident and more likely to follow AI-generated recommendations when supported by transparent explanations such as SHAP plots.
“Mixed-method evaluations show that clinicians are more confident and more likely to follow AI-generated recommendations when supported by transparent explanations such as SHAP plots426,427.”
From Artificial intelligence-driven multi-omics approaches in Alzheimer's disease: Progress, challenges, and future directions (2025) · cites this paper as [426]
In “The tool outputs must be comprehensible and actionable” (page unavailable), the paper recommends user-friendly visualisations and says explainability methods can clarify input–output relationships. It does not report mixed-method evaluations showing that explanations such as SHAP plots increase clinicians’ confidence or their likelihood of following AI recommendations; it also cautions that explanations can be misleading. (LLM, conf=0.78)
Experimental — accuracy not yet measured
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Cites
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“47 This requires the provision of educational resources, 48 sets of AI competencies 49 52 Concurrently, data privacy and security must be safe-guarded under umbrella instruments such as the General Data Protection Regulation.”
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“AI systems initially intended to lower healthcare costs often end up requiring substantial human oversight, illustrating the complexities involved in integrating AI effectively into clinical workflows without sacrificing clinician autonomy or patient safety [9,10].”
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EXAIM: Explainable AI Middleware for Real-Time Multi-Agent Clinical Decision Support
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- Authors
- Scott, I. A., van der Vegt, A., Lane, P., McPhail, S., & Magrabi, F.
- Affiliations
- The University of Queensland (AU)
- Digital Health Centre, The University of Queensland Faculty of Medicine and Biomedical Sciences, Herston, Queensland, Australia
- Prince Charles Hospital (AU)
- Queensland University of Technology (AU)
- Macquarie University (AU)
- Corresponding author
- Scott, Ian A.
- Venue
- BMJ Health & Care Informatics
- Publisher
- BMJ
- Published
- 2024-05
- Volume
- 31
- Issue
- 1
- Pages
- e100971
- ISSN
- 2632-1009 (ISSN-L)
- PMC
- PMC11141172
- OpenAlex
- W4399164534
- Cited by
- 65
- References
- 11
- Citations by year
- 2026: 39 · 2025: 25 · 2024: 1
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMJ Health & Care Informatics (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
- Keywords
- artificial intelligence, computerised decision support, clinician adoption, machine learning, clinical decision-making, technology acceptance, implementation barriers, system readiness, AI adoption strategy, point-of-care devices
- MeSH terms
- Machine Learning, Artificial Intelligence, Australia, Humans, Decision Support Systems, Clinical
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