Cited by 65Artificial Intelligence in Healthcare and EducationElectronic Health Records SystemsTechnology and Human Factors in Education and Health

Achieving large-scale clinician adoption of AI-enabled decision support

Open access
Scott, Ian A., van der Vegt, Anton, Lane, Paul, McPhail, Steven, Magrabi, Farah·2024·BMJ Health & Care Informatics

Abstract

Computerised decision support (CDS) tools enabled by artificial intelligence (AI) seek to enhance accuracy and efficiency of clinician decision-making at the point of care. Statistical models developed using machine learning (ML) underpin most current tools. However, despite thousands of models and hundreds of regulator-approved tools internationally, large-scale uptake into routine clinical practice has proved elusive. While underdeveloped system readiness and investment in AI/ML within Australia and perhaps other countries are impediments, clinician ambivalence towards adopting these tools at scale could be a major inhibitor. We propose a set of principles and several strategic enablers for obtaining broad clinician acceptance of AI/ML-enabled CDS tools.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/bmjhci-2023-100971

Cites

11 of 11 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • AI systems initially intended to lower healthcare costs often end up requiring substantial human oversight.

    “AI systems initially intended to lower healthcare costs often end up requiring substantial human oversight, illustrating the complexities involved in integrating AI effectively into clinical workflows without sacrificing clinician autonomy or patient safety [9,10].”

    From Enhancing Clinician Trust in AI Diagnostics: A Dynamic Framework for Confidence Calibration and Transparency (2025) · cites this paper as [10]

    In “The tool must not incur excessive opportunity cost or environmental impacts” (page unavailable), the paper describes costs for clinician involvement and ongoing maintenance. Its governance section also calls for ongoing monitoring and auditing. It does not say that AI systems are initially intended to lower healthcare costs or that they often end up requiring substantial human oversight. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • Mixed-method evaluations show that clinicians are more confident and more likely to follow AI-generated recommendations when supported by transparent explanations such as SHAP plots.

    “Mixed-method evaluations show that clinicians are more confident and more likely to follow AI-generated recommendations when supported by transparent explanations such as SHAP plots426,427.”

    From Artificial intelligence-driven multi-omics approaches in Alzheimer's disease: Progress, challenges, and future directions (2025) · cites this paper as [426]

    In “The tool outputs must be comprehensible and actionable” (page unavailable), the paper recommends user-friendly visualisations and says explainability methods can clarify input–output relationships. It does not report mixed-method evaluations showing that explanations such as SHAP plots increase clinicians’ confidence or their likelihood of following AI recommendations; it also cautions that explanations can be misleading. (LLM, conf=0.78)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 44

  1. [1]Yin J, Ngiam KY, Teo HH. Role of artificial intelligence tools in real-life clinical practice: systematic review. J Med Internet Res 2021; 23: e25759. 10.2196/25759 33885365 PMC8103304 · DOI · Paper page
  2. [2]Benjamens S, Dhunnoo P, Meskó B. The state of artificial intelligence-based FDA-approved medical devices and algorithms: an online database. NPJ Digit Med 2020; 3: 118. 10.1038/s41746-020-00324-0 32984550 PMC7486909 · DOI · Paper page
  3. [3]Magrabi F, Lyell D, Coiera E. Automation in contemporary clinical information systems: a survey of AI in clinical settings. Yearb Med Inform 2023; 32: 115– 26. 10.1055/s-0043-1768733 38147855 PMC10751141 · DOI
  4. [4]Coiera EW, Verspoor K, Hansen DP. We need to chat about artificial intelligence. Med J Aust 2023; 219: 98– 100. 10.5694/mja2.51992 37302124 PMC10952508 · DOI
  5. [6]Terry AL, Kueper JK, Beleno R, et al. Is primary health care ready for artificial intelligence? What do primary health care stakeholders say? BMC Med Inform Decis Mak 2022; 22: 237. 10.1186/s12911-022-01984-6 36085203 PMC9461192 · DOI
  6. [7]Magrabi F, Cresswell K, Fraser HS. International dimensions of clinical decision support systems. In: Greenes R, Fiol GD, eds. Clinical decision support and beyond: progress and opportunities in knowledge-enhanced health and Healthcare. London: Elsevier Academic Press, 2023: 145– 88.
  7. [8]van der Vegt AH, Scott IA, Dermawan K, et al. Implementation frameworks for end-to-end clinical AI: derivation of the SALIENT framework. J Am Med Inform Assoc 2023; 30: 1503– 15. 10.1093/jamia/ocad088 37208863 PMC10436156 · DOI · Paper page
  8. [10]Barker N, Scott IA, Seaton R, et al. Recognition and management of hospital-acquired sepsis among general medical inpatients in queensland public hospitals. Int J Gen Med 2023; 16: 1039– 46. 36987405 PMC10039973
  9. [11]Tarnutzer AA, Lee S-H, Robinson KA, et al. ED misdiagnosis of cerebrovascular events in the era of modern neuroimaging: a meta-analysis. Neurology 2017; 88: 1468– 77. 10.1212/WNL.0000000000003814 28356464 PMC5386439 · DOI
  10. [12]Shimabukuro DW, Barton CW, Feldman MD, et al. Effect of a machine learning-based severe sepsis prediction algorithm on patient survival and hospital length of stay: a randomised clinical trial. BMJ Open Respir Res 2017; 4: e000234. 10.1136/bmjresp-2017-000234 PMC5687546 29435343 · DOI · Paper page
  11. [13]Gunda B, Neuhaus A, Sipos I, et al. Improved stroke care in a primary stroke centre using AI decision support. Cerebrovasc Dis Extra 2022; 12: 28– 32. 10.1159/000522423 35134802 PMC9082202 · DOI
  12. [14]Sanders S, Doust J, Glasziou P. A systematic review of studies comparing diagnostic clinical prediction rules with clinical judgment. PLoS One 2015; 10: e0128233. 10.1371/journal.pone.0128233 26039538 PMC4454557 · DOI
  13. [15]Challen R, Denny J, Pitt M, et al. Artificial intelligence, bias and clinical safety. BMJ Qual Saf 2019; 28: 231– 7. 10.1136/bmjqs-2018-008370 PMC6560460 30636200 · DOI · Paper page
  14. [16]Huo W, Yuan X, Li X, et al. Increasing acceptance of medical AI: the role of medical staff participation in AI development. Int J Med Inform 2023; 175: 105073. 10.1016/j.ijmedinf.2023.105073 37119693 PMC10125218 · DOI
  15. [17]Abrams D, Montesi SB, Moore SKL, et al. Powering bias and clinically important treatment effects in randomized trials of critical illness. Crit Care Med 2020; 48: 1710– 9. 10.1097/CCM.0000000000004568 33031148 PMC7708428 · DOI
  16. [18]Ferreira ML, Ferreira PH, Herbert RD, et al. People with low back pain typically need to feel ‘much better’ to consider intervention worthwhile: an observational study. Aust J Physiother 2009; 55: 123– 7. 10.1016/s0004-9514(09)70042-x 19463083 · DOI
  17. [19]Susanto AP, Lyell D, Widyantoro B, et al. Effects of machine learning-based clinical decision support systems on decision-making, care delivery, and patient outcomes: a scoping review. J Am Med Inform Assoc 2023; 30: 2050– 63. 10.1093/jamia/ocad180 37647865 PMC10654852 · DOI
  18. [21]Liu X, Faes L, Kale AU, et al. A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis. Lancet Digit Health 2019; 1: e271– 97. 10.1016/S2589-7500(19)30123-2 33323251 · DOI · Paper page
  19. [22]Nagendran M, Chen Y, Lovejoy CA, et al. Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies. BMJ 2020; 368: m689. 10.1136/bmj.m689 32213531 PMC7190037 · DOI · Paper page
  20. [23]Kwan JL, Lo L, Ferguson J, et al. Computerised clinical decision support systems and absolute improvements in care: meta-analysis of controlled clinical trials. BMJ 2020; 370: m3216. 10.1136/bmj.m3216 32943437 PMC7495041 · DOI
  21. [25]Lyons PG, Hofford MR, Yu SC, et al. Factors associated with variability in the performance of a proprietary sepsis prediction model across 9 networked hospitals in the US. JAMA Intern Med 2023; 183: 611– 2. 10.1001/jamainternmed.2022.7182 37010858 PMC10071393 · DOI · Paper page
  22. [26]Sendak MP, Gao M, Brajer N, et al. Presenting machine learning model information to clinical end users with model facts labels. NPJ Digit Med 2020; 3: 41. 10.1038/s41746-020-0253-3 32219182 PMC7090057 · DOI · Paper page
  23. [27]Tschandl P, Rinner C, Apalla Z, et al. Apalla Z, et al Human-computer collaboration for skin cancer recognition. Nat Med 2020; 26: 1229– 34. 10.1038/s41591-020-0942-0 32572267 · DOI · Paper page
  24. [29]Bienefeld N, Boss JM, Lüthy R, et al. Solving the explainable AI conundrum by bridging clinicians’ needs and developers’ goals. NPJ Digit Med 2023; 6: 94. 10.1038/s41746-023-00837-4 37217779 PMC10202353 · DOI · Paper page
  25. [30]Tonekaboni S, Joshi S, McCradden MD, et al. What clinicians want: contextualising explainable machine learning for clinical end use. Proc Mach Learn Res 2019; 106: 359– 80.
  26. [31]van der Veer SN, Riste L, Cheraghi-Sohi S, et al. Trading off accuracy and explainability in AI decision-making: findings from 2 citizens' juries. J Am Med Inform Assoc 2021; 28: 2128– 38. 10.1093/jamia/ocab127 34333646 PMC8522832 · DOI
  27. [32]Lyell D, Wang Y, Coiera E, et al. More than models: an analysis of safety events involving ML-enabled medical devices reported to the FDA. J Am Med Inform Assoc 2023; 30: 1227– 36. 10.1093/jamia/ocad065 37071804 PMC10280342 · DOI
  28. [33]Asan O, Choudhury A. Research trends in artificial intelligence tools in human factors health care: mapping review. JMIR Hum Factors 2021; 8: e28236. 10.2196/28236 34142968 PMC8277302 · DOI · Paper page
  29. [35]Reddy S, Allan S, Coghlan S, et al. A governance model for application of AI in healthcare. J Am Med Inform Assoc 2020; 27: 491– 7. 10.1093/jamia/ocz192 31682262 PMC7647243 · DOI · Paper page
  30. [36]Hwang TJ, Kesselheim AS, Vokinger KN. Life-cycle regulation of artificial Intelligence- and machine learning-based software devices in medicine. JAMA 2019; 322: 2285– 6. 10.1001/jama.2019.16842 31755907 · DOI
  31. [37]Bitterman DS, Aerts H, Mak RH. Approaching autonomy in medical artificial intelligence. Lancet Digit Health 2020; 2: e447– 9. 10.1016/S2589-7500(20)30187-4 33328110 · DOI · Paper page
  32. [38]Feng J, Phillips RV, Malenica I, et al. Clinical artificial intelligence quality improvement: towards continual monitoring and updating of AI models in healthcare. NPJ Digit Med 2022; 5: 66. 10.1038/s41746-022-00611-y 35641814 PMC9156743 · DOI · Paper page
  33. [40]Sauerbrei A, Kerasidou A, Lucivero F, et al. The impact of artificial intelligence on the person-centred, doctor-patient relationship: some problems and solutions. BMC Med Inform Decis Mak 2023; 23: 73. 10.1186/s12911-023-02162-y 37081503 PMC10116477 · DOI
  34. [41]Abbasgholizadeh Rahimi S, Cwintal M, Huang Y, et al. Tool of artificial intelligence in shared decision making: scoping review. JMIR Med Inform 2022; 10: e36199. 10.2196/36199 35943793 PMC9399841 · DOI
  35. [43]Bloomfield PS, Clutton-Brock P, Pencheon E, et al. Artificial intelligence in the NHS: climate and emissions. J Clim Change Health 2021; 4: 100056. 10.1016/j.joclim.2021.100056 · DOI
  36. [44]Voets MM, Veltman J, Slump CH, et al. Systematic review of health economic evaluations focused on artificial intelligence in healthcare: the tortoise and the cheetah. Value Health 2022; 25: 340– 9. 10.1016/j.jval.2021.11.1362 35227444 · DOI · Paper page
  37. [45]Liu VX, Bates DW, Wiens J, et al. The number needed to benefit: estimating the value of predictive analytics in healthcare. J Am Med Inform Assoc 2019; 26: 1655– 9. 10.1093/jamia/ocz088 31192367 PMC6857505 · DOI
  38. [46]Parsons R, Blythe R, Cramb SM, et al. Integrating economic considerations into cutpoint selection may help align clinical decision support toward value-based healthcare. J Am Med Inform Assoc 2023; 30: 1103– 13. 10.1093/jamia/ocad042 36970849 PMC10198528 · DOI
  39. [47]Scott I, Carter S, Coiera E. A clinician checklist for assessing the suitability of machine learning applications in healthcare. BMJ Health Care Inform 2021; 28: e100251. 10.1136/bmjhci-2020-100251 PMC7871244 33547086 · DOI
  40. [48]Scott IA. Demystifying machine learning: a primer for physicians. Intern Med J 2021; 51: 1388– 400. 10.1111/imj.15200 33462882 · DOI
  41. [50]Wisniewski H, Gorrindo T, Rauseo-Ricupero N, et al. The role of digital navigators in promoting clinical care and technology integration into practice. Digit Biomark 2021; 4: 119– 35. 10.1159/000510144 PMC7768140 33442585 · DOI
  42. [51]Schwartz JM, Moy AJ, Rossetti SC, et al. Clinician involvement in research on machine learning-based predictive clinical decision support for the hospital setting: a scoping review. J Am Med Inform Assoc 2021; 28: 653– 63. 10.1093/jamia/ocaa296 33325504 PMC7936403 · DOI
  43. [53]Corbin CK, Maclay R, Acharya A, et al. DEPLOYR: a technical framework for deploying custom real-time machine learning models into the electronic medical record. J Am Med Inform Assoc 2023; 30: 1532– 42. 10.1093/jamia/ocad114 37369008 PMC10436147 · DOI
  44. [55]Yousefi Nooraie R, Lyons PG, Baumann AA, et al. Equitable implementation of artificial intelligence in medical imaging: what can be learned from implementation science? PET Clinics 2021; 16: 643– 53. 10.1016/j.cpet.2021.07.002 34537134 PMC12121049 · DOI

Cited by

Sorted by citations

Authors
Scott, I. A., van der Vegt, A., Lane, P., McPhail, S., & Magrabi, F.
Affiliations
  • The University of Queensland (AU)
  • Digital Health Centre, The University of Queensland Faculty of Medicine and Biomedical Sciences, Herston, Queensland, Australia
  • Prince Charles Hospital (AU)
  • Queensland University of Technology (AU)
  • Macquarie University (AU)
Corresponding author
Scott, Ian A.
Venue
BMJ Health & Care Informatics
Publisher
BMJ
Published
2024-05
Volume
31
Issue
1
Pages
e100971
ISSN
2632-1009 (ISSN-L)
OpenAlex
W4399164534
Cited by
65
References
11
Citations by year
2026: 39 · 2025: 25 · 2024: 1
FWCI
6.08
Type
journal article
Language
en
Open access
Locations
  • BMJ Health & Care Informatics (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
Keywords
artificial intelligence, computerised decision support, clinician adoption, machine learning, clinical decision-making, technology acceptance, implementation barriers, system readiness, AI adoption strategy, point-of-care devices
MeSH terms
Machine Learning, Artificial Intelligence, Australia, Humans, Decision Support Systems, Clinical

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review