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Cited by 25Health Systems, Economic Evaluations, Quality of LifePhysical Activity and HealthTreatment of Major Depression

Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK

Open access
Turner, David, Carter, Tim, Sach, Tracey, Guo, Boliang, Callaghan, Patrick·2017·BMJ Open
DOI 10.1136/bmjopen-2017-016211PMC PMC5719311
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Abstract

Objectives: To assess the cost-effectiveness of preferred intensity exercise programme for young people with depression compared with a treatment as usual control group. Design: A ‘within trial’ cost-effectiveness and cost-utility analysis conducted alongside a randomised controlled trial. The perspective of the analysis was the UK National Health Service and social services. Setting: The intervention was provided in a community leisure centre setting. Participants: 86 young people aged 14–17 years attending Tier 2 and Tier 3 CAMHS (Child and Adolescent Mental Health Services) outpatient services presenting with depression. Interventions: The intervention comprised 12 separate sessions of circuit training over a 6-week period. Sessions were supervised by a qualified exercise therapist. Participants also received treatment as usual. The comparator group received treatment as usual. Results: We found improvements in the Children’s Depression Inventory-2 (CDI-2) and estimated cost-effectiveness at £61 per point improvement in CDI-2 for the exercise group compared with control. We found no evidence that the exercise intervention led to differences in quality-adjusted life years (QALY). QALYs were estimated using the EQ-5D-5L (5-level version of EuroQol-5 dimension). Conclusions: There is evidence that exercise can be an effective intervention for adolescents with depression and the current study shows that preferred intensity exercise could also represent a cost-effective intervention in terms of the CDI-2. Trial registration number: NCT01474837.

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  • Other evidence for specific interventions targeting disorders that occur mainly in young people (such as depressive or eating disorders) have also been found to be highly cost-effective.

    “Other evidence for specific interventions targeting disorders that occur mainly in young people (such as depressive or eating disorders) have also been found to be highly cost-effective. 430-432”

    From The Lancet Psychiatry Commission on youth mental health (2024) · cites this paper as [431]

    The Conclusion says preferred-intensity exercise could be cost-effective for adolescents with depression when measured by improvement in CDI-2 scores. But the Results > Outcomes and Discussion report substantial uncertainty and no evidence of a QALY improvement, so this study does not establish that the intervention is highly cost-effective. The paper addresses depression, not eating disorders. (LLM, conf=0.88)

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Cited by

Sorted by citations

Authors
Turner, D., Carter, T., Sach, T., Guo, B., & Callaghan, P.
Affiliations
  • University of East Anglia (GB)
  • University of Nottingham (GB)
Corresponding author
Turner, David
ORCID
Venue
BMJ Open
Publisher
BMJ
Published
2017-11
Volume
7
Issue
11
Pages
e016211
ISSN
2044-6055 (ISSN-L)
DOI
10.1136/bmjopen-2017-016211
PMC
PMC5719311
OpenAlex
W2769330021
Cited by
25
References
8
Citations by year
2026: 1 · 2025: 7 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 1
FWCI
2.46
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • BMJ Open (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research Open (London South Bank University) (acceptedVersion)
  • UEA Digital Repository (University of East Anglia) (acceptedVersion, cc-by)
  • Research Open (London South Bank University) (acceptedVersion, cc-by)
  • Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
  • ePrints Soton (University of Southampton) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
Funders
  • National Institute for Health and Care Research (PB-PG-1208-18097)
  • Research for Patient Benefit Programme
Topics
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
adolescent depression, exercise therapy, circuit training, cost-effectiveness, cost-utility analysis, child and adolescent mental health services, quality-adjusted life years
MeSH terms
Adolescent, Cost-Benefit Analysis, Depression, Exercise Therapy, Female, United Kingdom, Humans, Male, Quality of Life, Single-Blind Method, Quality-Adjusted Life Years

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