Cited by 1,056Treatment of Major DepressionChild and Adolescent Psychosocial and Emotional DevelopmentPsychological Treatments and Disorders

Practice parameter for the assessment and treatment of children and adolescents with depressive disorders

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Birmaher, Boris, Brent, David·2007·Journal of the American Academy of Child & Adolescent Psychiatry

Abstract

This practice parameter describes the epidemiology, clinical picture, differential diagnosis, course, risk factors, and pharmacological and psychotherapy treatments of children and adolescents with major depressive or dysthymic disorders. Side effects of the antidepressants, particularly the risk of suicidal ideation and behaviors are discussed. Recommendations regarding the assessment and the acute, continuation, and maintenance treatment of these disorders are based on the existent scientific evidence as well as the current clinical practice.

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Registry

Crossref · 10.1097/chi.0b013e318145ae1c

Cites

190 of 190 references verified0 citation errors · 0 not checkable

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  • Some adolescents with depression may have difficulty verbalizing feelings or may deny being depressed or suicidal.

    “Notably, some adolescents with depression may have difficulty in verbalizing their feelings or may deny that they are depressed or suicidal.”

    From Adolescent Suicide—Understanding Unique Risks and Opportunities for Trauma Centers to Recognize, Intervene, and Prevent a Leading Cause of Death (2022) · cites this paper as [54]

    Evaluation Recommendation 3 says children may have difficulty verbalizing their feelings or may deny being depressed, in the context of assessing children and adolescents. The paper recommends assessing suicidality in Recommendation 4, but the passages do not say that adolescents may deny being suicidal; that part of the claim is unsupported. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • These adolescents may instead present with mood lability, irritability, low frustration tolerance, temper tantrums or agitation, somatic complaints, and/or social withdrawal.

    “They may instead present with mood lability, irritability, low frustration tolerance, temper tantrums or agitation, somatic complaints, and/or social withdrawal instead of verbalizing feelings of depression [54].”

    From Adolescent Suicide—Understanding Unique Risks and Opportunities for Trauma Centers to Recognize, Intervene, and Prevent a Leading Cause of Death (2022) · cites this paper as [54]

    The Clinical Presentation passage lists mood lability, irritability, low frustration tolerance, temper tantrums, somatic complaints, and social withdrawal instead of verbalizing depression. It describes this presentation in children, not specifically adolescents, and does not include agitation in that list. No page number is supplied for the passage. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Of these, 4 (19%) included a specific statement on the risk of misinterpreting withdrawal symptoms as depressive relapse.

    “and of these, 4 (19%) included a specific statement on the risk of misinterpreting withdrawal symptoms as depressive relapse, stating that withdrawal symptoms may ‘mimic’, 48 ‘be misdiagnosed as’, 2 ‘mistaken for’ 28 or ‘be hard to distinguish from’ 36 relapse of depressive symptoms.”

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Research works printed but not linked: 1

  1. [40]40. Daviss WB, Bentivoglio P, Racusin R, Brown K, Bostic J, Wiley L (2001), Bupropion sustained release in adolescents with comorbid attention deficit hyperactivity. J Am Acad Child Adolesc Psychiatry 40:307Y314

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Authors
Birmaher, B., & Brent, D.
Affiliations
American Academy of Child and Adolescent Psychiatry (US)
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2007-11
Volume
46
Issue
11
Pages
1503-1526
ISSN
0890-8567 (ISSN-L)
OpenAlex
W2183950985
Cited by
1,056
References
190
Citations by year
2026: 19 · 2025: 44 · 2024: 55 · 2023: 46 · 2022: 48 · 2021: 113 · 2020: 69 · 2019: 44 · 2018: 68 · 2017: 54 · 2016: 69 · 2015: 50 · 2014: 59 · 2013: 59 · 2012: 54
FWCI
29.39
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
Keywords
childhood depression, adolescent depression, major depressive disorder, dysthymia, antidepressant side effects, suicidal ideation, suicidal behavior, differential diagnosis, risk factors, course of depression, psychotherapy, pharmacotherapy, maintenance therapy, continuation treatment, acute treatment, clinical evaluation
MeSH terms
Adolescent, Child, Child, Preschool, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Practice Patterns, Physicians', Psychotic Disorders, Prevalence

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