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Using routinely collected data to understand and predict adverse outcomes in opioid agonist treatment: Protocol for the Opioid Agonist Treatment Safety (OATS) Study.
Abstract
Introduction: North America is amid an opioid use epidemic. Opioid agonist treatment (OAT) effectively reduces extramedical opioid use and related harms. As with all pharmacological treatments, there are risks associated with OAT, including fatal overdose. There is a need to better understand risk for adverse outcomes during and after OAT, and for innovative approaches to identifying people at greatest risk of adverse outcomes. The Opioid Agonist Treatment and Safety study aims to address these questions so as to inform the expansion of OAT in the USA. Methods and analysis: This is a retrospective cohort study using linked, routinely collected health data for all people seeking OAT in New South Wales, Australia, between 2001 and 2017. Linked data include hospitalisation, emergency department presentation, mental health diagnoses, incarceration and mortality. We will use standard regression techniques to model the magnitude and risk factors for adverse outcomes (eg, mortality, unplanned hospitalisation and emergency department presentation, and unplanned treatment cessation) during and after OAT, and machine learning approaches to develop a risk-prediction model. Ethics and dissemination: This study has been approved by the Population and Health Services Research Ethics Committee (2018HRE0205). Results will be reported in accordance with the REporting of studies Conducted using Observational Routinely-collected health Data statement.
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“The Opioid Agonist Treatment Safety (OATS) study is an administrative data linkage cohort study in New South Wales, Australia, which includes OAT permit records (with methadone or buprenorphine) for every person accessing OAT for opioid use disorder treatment in New South Wales from 2001 to 2018 [42,43].”
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Benchimol, E. I., Smeeth, L., Guttmann, A., Harron, K., Moher, D., Petersen, I., Sørensen, H. T., von Elm, E., Langan, S. M., & RECORD Working Committee (2015) · PLOS Medicine · doi:10.1371/journal.pmed.1001885 · Cited by 5,749
Sordo, L., Barrio, G., Bravo, M. J., Indave, B. I., Degenhardt, L., Wiessing, L., Ferri, M., & Pastor-Barriuso, R. (2017) · BMJ · doi:10.1136/bmj.j1550 · Cited by 1,816 · cited 1×
“26–28 Additional adverse outcomes during OAT may include non-fatal overdoses, accidents 29 or cardiac problems resulting from QT interval prolongation.”
BackgroundOverdose deaths involving opioids, cocaine, and psychostimulants—United States, 2015–2016.
Seth, P., Scholl, L., Rudd, R. A., & Bacon, S. (2018) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6712a1 · Cited by 821
Kessler, R. C., Warner, C. H., Ivany, C., Petukhova, M. V., Rose, S., Bromet, E. J., Brown, M., Cai, T., Colpe, L. J., Cox, K. L., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.1754 · Cited by 447
Research works printed but not linked: 33
- 10.1016/j.drugalcdep.2017.07.018 · DOI
- 10.1001/jama.2015.11859 · DOI · Paper page
- 10.1002/pds.3989 · DOI
- Karanges, 2018, Trends in opioid utilisation in Australia, 2006-2015: Insights from multiple metrics, Pharmacoepidemiol Drug Saf, 27, 504, 10.1002/pds.4369 · DOI
- Jones, 2018, Rapid change in fentanyl prevalence in a community-based, high-risk sample, JAMA Psychiatry, 75, 298, 10.1001/jamapsychiatry.2017.4432 · DOI
- 10.1001/jama.2018.2844 · DOI
- Conrad, 2015, Community outbreak of hiv infection linked to injection drug use of oxymorphone--Indiana, 2015, MMWR Morb Mortal Wkly Rep, 64, 443
- 10.2105/AJPH.2014.302142 · DOI
- Stanley, 2012, Hepatitis C virus infections among young adults - rural Wisconsin, 2010, Morbidity and Mortality Weekly Report, 61, 358
- Onofrey, 2011, Hepatitis C virus infection among adolescents and young adults - Massachusetts, 2002-2009, Morbidity and Mortality Weekly Report, 60, 538
- Peters, 2016, HIV infection linked to injection use of oxymorphone in Indiana, 2014-2015, N Engl J Med, 375, 229, 10.1056/NEJMoa1515195 · DOI
- Nielsen S , Larance B , Degenhardt L , et al . Opioid agonist treatment for pharmaceutical opioid dependent people. Cochrane Database Syst Rev 2016;2016;172. Art. No. CD011117.doi:10.1002/14651858.CD011117.pub2 · DOI
- 10.1111/j.1360-0443.2010.03140.x · DOI · Paper page
- Platt, 2018, Needle and syringe programmes and opioid substitution therapy for preventing HCV transmission among people who inject drugs: findings from a Cochrane Review and meta-analysis, Addiction, 113, 545, 10.1111/add.14012 · DOI
- 10.1136/bmj.e5945 · DOI · Paper page
- Kendall CE , Boucher LM , Mark AE , et al . A cohort study examining emergency department visits and hospital admissions among people who use drugs in Ottawa, Canada. Harm Reduction Journal 2017;14(1. · DOI
- Robertson, 2018, Associations between pharmacotherapy for opioid dependence and clinical and criminal justice outcomes among adults with co-occurring serious mental illness, J Subst Abuse Treat, 86, 17, 10.1016/j.jsat.2017.12.003 · DOI
- Mohlman, 2016, Impact of medication-assisted treatment for opioid addiction on medicaid expenditures and health services utilization rates in Vermont, J Subst Abuse Treat, 67, 9, 10.1016/j.jsat.2016.05.002 · DOI
- Krebs, 2014, Dynamics in the costs of criminality among opioid dependent individuals, Drug Alcohol Depend, 144, 193, 10.1016/j.drugalcdep.2014.09.007 · DOI
- 10.1080/10550880902772373 · DOI
- Russolillo A , Moniruzzaman A , McCandless LC , et al . Associations between methadone maintenance treatment and crime: a 17-year longitudinal cohort study of Canadian provincial offenders. Addiction 2018;113.doi:10.1111/add.14059 · DOI
- Kimber, 2015, Mortality risk of opioid substitution therapy with methadone versus buprenorphine: a retrospective cohort study, Lancet Psychiatry, 2, 901, 10.1016/S2215-0366(15)00366-1 · DOI
- Hickman, 2018, The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom, Addiction, 113, 1461, 10.1111/add.14188 · DOI
- Bramness, 2012, An increased risk of motor vehicle accidents after prescription of methadone, Addiction, 107, 967, 10.1111/j.1360-0443.2011.03745.x · DOI
- Kao, 2015, Arrhythmia associated with buprenorphine and methadone reported to the food and drug administration, Addiction, 110, 1468, 10.1111/add.13013 · DOI
- 10.1111/j.1526-4637.2010.00877.x · DOI
- 10.1016/j.drugalcdep.2011.07.019 · DOI
- Larance, 2016, Diversion and injection of buprenorphine-naloxone film two years post-introduction in Australia, Drug Alcohol Rev, 35, 83, 10.1111/dar.12344 · DOI
- 10.1097/ADM.0000000000000166 · DOI
- 10.1177/183335830803700208 · DOI
- 10.1023/A:1010933404324 · DOI · Paper page
- 10.1111/j.1467-9868.2005.00503.x · DOI · Paper page
- 10.1111/j.1467-9868.2005.00503.x · DOI · Paper page
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Brothers, T. D., Lewer, D., Jones, N., Colledge-Frisby, S., Farrell, M., Hickman, M., Webster, D., Hayward, A., & Degenhardt, L. (2022) · PLOS Medicine · doi:10.1371/journal.pmed.1004049 · Cited by 25
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Metadata
- Authors
- Larney, S., Hickman, M., Fiellin, D. A., Dobbins, T., Nielsen, S., Jones, N. R., Mattick, R. P., Ali, R., & Degenhardt, L.
- Affiliations
- National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
- Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
- Schools of Medicine and Public Health, Yale University, New Haven, Connecticut, USA
- Monash Addiction Research Centre, Monash University, Melbourne, Victoria, Australia
- Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia
- ORCID
- Larney, Sarah
- Venue
- BMJ Open
- Publisher
- BMJ
- Published
- 2018-08
- Volume
- 8
- Issue
- 8
- Pages
- e025204
- ISSN
- 2044-6055
- PMC
- PMC6078240
- Cited by
- 26
- References
- 4
- Language
- en
- Funders
- National Institute on Drug Abuse
- National Health and Medical Research Council
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