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Development of an evidence-based framework of factors contributing to patient safety incidents in hospital settings: a systematic review
Open accessAbstract
OBJECTIVE: The aim of this systematic review was to develop a 'contributory factors framework' from a synthesis of empirical work which summarises factors contributing to patient safety incidents in hospital settings. DESIGN: A mixed-methods systematic review of the literature was conducted. DATA SOURCES: Electronic databases (Medline, PsycInfo, ISI Web of knowledge, CINAHL and EMBASE), article reference lists, patient safety websites, registered study databases and author contacts. ELIGIBILITY CRITERIA: Studies were included that reported data from primary research in secondary care aiming to identify the contributory factors to error or threats to patient safety. RESULTS: 1502 potential articles were identified. 95 papers (representing 83 studies) which met the inclusion criteria were included, and 1676 contributory factors extracted. Initial coding of contributory factors by two independent reviewers resulted in 20 domains (eg, team factors, supervision and leadership). Each contributory factor was then coded by two reviewers to one of these 20 domains. The majority of studies identified active failures (errors and violations) as factors contributing to patient safety incidents. Individual factors, communication, and equipment and supplies were the other most frequently reported factors within the existing evidence base. CONCLUSIONS: This review has culminated in an empirically based framework of the factors contributing to patient safety incidents. This framework has the potential to be applied across hospital settings to improve the identification and prevention of factors that cause harm to patients.
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“For example, the social influences and environmental context and resource domains point to organisational and systems context for change and can be further elaborated, e.g. by Normalisation Process Theory [66], the Consolidated Framework For Implementation Research [67] and the Yorkshire Contributory Factors Framework [68].”
From A guide to using the Theoretical Domains Framework of behaviour change to investigate implementation problems (2017) · cites this paper as [68]
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Metadata
- Authors
- Lawton, R., McEachan, R. R. C., Giles, S. J., Sirriyeh, R., Watt, I. S., & Wright, J.
- Affiliations
- University of Leeds (GB)
- Bradford Royal Infirmary (GB)
- University of York (GB)
- Corresponding author
- Lawton, Rebecca
- Venue
- BMJ Quality & Safety
- Publisher
- BMJ
- Published
- 2012-03-15
- Volume
- 21
- Issue
- 5
- Pages
- 369-380
- ISSN
- 1475-3898 (ISSN-L)
- 2044-5415
- 2044-5423
- PMC
- PMC3332004
- OpenAlex
- W2164086521
- Cited by
- 311
- References
- 129
- Citations by year
- 2026: 13 · 2025: 14 · 2024: 16 · 2023: 21 · 2022: 21 · 2021: 34 · 2020: 24 · 2019: 31 · 2018: 28 · 2017: 19 · 2016: 24 · 2015: 27 · 2014: 23 · 2013: 15
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ Quality & Safety (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
- Research Explorer (The University of Manchester) (submittedVersion, cc-by-nc)
- Funders
- National Institute for Health and Care Research (RP-PG-0108-10049)
- Programme Grants for Applied Research (RP-PG-0108-10049)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Patient Safety and Medication Errors
- Health Sciences › Nursing › Leadership and Management › Hospital Admissions and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Healthcare Quality and Management
- Keywords
- patient safety incidents, hospital errors, active failures, team factors, communication, patient harm prevention, secondary care
- MeSH terms
- Data Interpretation, Statistical, Hospitals, Humans, Quality Assurance, Health Care, Databases, Bibliographic, Adverse Drug Reaction Reporting Systems, Medical Errors, Empirical Research, Evidence-Based Practice, Root Cause Analysis, Patient Safety
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