Varying effects of psychotropic medications on fracture risk in older people
Abstract
Udgivelsesdato: 2009-Feb
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Some studies have reported higher prevalence rates of osteoporotic fractures in patients with chronic schizophrenia, entirely or partly independent of the use of antipsychotics.
“Some of these studies have reported higher prevalence rates of osteoporotic fractures in patients with chronic schizophrenia, entirely or partly independent of the use of AP (504,505).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [505]
Although lithium has a potentially negative impact on bone metabolism, it is associated with lower fracture risk (OR=0.6) and seems to be protective against fractures.
“Although lithium has a potentially negative impact on bone metabolism (470), it is associated with lower fracture risk (OR=0.6)and, thus, seems to be protective against fractures (504,505).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [505]
SSRIs seem to be associated with the highest adjusted odds of osteoporotic fractures (OR=1.5).
“SSRIs seem to be associated with the highest adjusted odds of osteoporotic fractures (OR=1.5)(504,505, 508).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [505]
Cited by
Sorted by citations
DE HERT, M., CORRELL, C. U., BOBES, J., CETKOVICH‐BAKMAS, M., COHEN, D., ASAI, I., DETRAUX, J., GAUTAM, S., MÖLLER, H., NDETEI, D. M., et al. (2011) · World Psychiatry · doi:10.1002/j.2051-5545.2011.tb00014.x · Cited by 2,488 · see citing works
“Some of these studies have reported higher prevalence rates of osteoporotic fractures in patients with chronic schizophrenia, entirely or partly independent of the use of AP (504,505).”
BackgroundCorrell, C. U., Detraux, J., De Lepeleire, J., & De Hert, M. (2015) · World Psychiatry · doi:10.1002/wps.20204 · Cited by 820 · see citing works
“Lithium is possibly associated with a reduced fracture risk (255,256) (Table 2).”
BackgroundMaj, M., Ïðåçèäåíò, È., Tasman, A., & Herrman, H. (2011)
- Authors
- Vestergaard, P.
- Corresponding author
- Peter Vestergaard
- ORCID
- Peter Vestergaard
- Venue
- Evidence Based Mental Health
- Publisher
- BMJ
- Published
- 2009-01-28
- Volume
- 12
- Issue
- 1
- Pages
- 25-25
- ISSN
- 1362-0347 (ISSN-L)
- 1468-960X
- OpenAlex
- W1969741292
- Cited by
- 3
- References
- 0
- Citations by year
- 2015: 1
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Evidence-Based Mental Health (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Keywords
- psychotropic drugs, fracture risk, older adults, falls, osteoporosis
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