The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Antioxidants in neonatal lung disease.
Open accessAbstract
During Ag stimulation of T cells, the recognition of B7 molecules by the CD28 costimulatory receptor increases the level of c-Fos, a component of the AP-1 transactivator known to bind the 5′ Il2 gene enhancer. In this study, we show that the costimulation of Fos transcription by CD28 is associated with increased binding of p300/CREB-binding protein (CBP) molecules at the Fos promoter, and is blocked by an adenoviral E1A molecular antagonist of p300/CBP. Furthermore, transcriptional activation by a C-terminal domain of CBP is strengthened when CD28 molecules are actively signaling. This increased amount and activity of p300/CBP molecules at the Fos gene correlated with higher histone H4 acetylation and RNA polymerase II association with the promoter. These data suggest a global mechanism whereby CD28 signaling influences the rate and intensity of new gene expression during Ag recognition via direct control over the coactivator function of p300/CBP.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Fe (II) reacting with unsaturated fatty acids in the presence of H 2 O 2 can initiate lipid peroxidation cascade in biological membranes and lipoproteins by production of HO•.”
From Iron, Oxidative Stress and Health (2012) · cites this paper as Fardy and Silverman, 1995
In the citing paper
“Lipid peroxidation increases membrane fragility of cell organelles such as mitochondria, lysosomes and endoplasmic reticulum leading to impaired cell function”
From Iron, Oxidative Stress and Health (2012) · cites this paper as Fardy and Silverman, 1995
Citations
Cites
Free radicals in biology and medicine
(1991) · General Pharmacology: The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Free Radicals in Biology and Medicine
Land, E. T. (1990) · International Journal of Radiation Biology · doi:10.1080/09553009014552071 · Cited by 4,854
Tissue Destruction by Neutrophils
Epstein, F. H., & Weiss, S. J. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200606 · Cited by 3,950
Tissue Destruction by Neutrophils
(1989) · New England Journal of Medicine · doi:10.1056/nejm198908033210513 · Cited by 3,635
Biology of disease: free radicals and tissue injury.
Freeman, B. Α., & Jd, C. (1982) · PubMed · Cited by 3,038
Northway, W. H., Rosan, R. C., & Porter, D. Y. (1967) · New England Journal of Medicine · doi:10.1056/nejm196702162760701 · Cited by 3,013
Radi, R., Beckman, J. S., Bush, K. M., & Freeman, B. A. (1991) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(91)90224-7 · Cited by 2,194
The respiratory burst of phagocytes.
Babior, B. M. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111249 · Cited by 898
Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn
KINSELLA, J. (1992) · The Lancet · doi:10.1016/0140-6736(92)92687-b · Cited by 730
Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.
Gaston, B., Reilly, J., Drazen, J. M., Fackler, J., Ramdev, P., Arnelle, D., Mullins, M. E., Sugarbaker, D. J., Chee, C., Singel, D. J., et al. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.23.10957 · Cited by 623
Research works printed but not linked: 3
- Raffin TA, Simon LM, Braun D. Impairment of phagocytosis by moderate hypoxia (40-60% oxygen) in lung macrophages. Lab Invest 1980; 42: 622.
- Kooy NW, Royall JA, Ye YZ, Kelly DP, Beckman JS. Peroxynitrite is produced during human adult respiratory distress syndrome. Am Jf Respir Crit Care Med 1994; 149: A814.
- Guitierrez H, Pitt B, Brockens M, Chumley P, Freeman B. Endogenously-produced and exogenously-administered nitric oxide modulates superoxide-dependant lung injury. Am Jf Respir Crit Care Med 1944; 149: A550.
Cited by
Iron, Oxidative Stress and Health
Udipi, S., Ghugre, P., & Gokhale, C. (2012) · Oxidative Stress - Molecular Mechanisms and Biological Effects · doi:10.5772/34975 · Cited by 17
Metadata
- Authors
- Fardy, C. H., & Silverman, M.
- Affiliations
- Leicester Royal Infirmary (GB)
- ORCID
- Silverman, M.
- Venue
- Archives of Disease in Childhood - Fetal and Neonatal Edition
- Publisher
- BMJ
- Published
- 1995-09
- Volume
- 73
- Issue
- 2
- Pages
- F112-F117
- ISSN
- 1359-2998 (ISSN-L)
- 1468-2052
- PMC
- PMC2528507
- OpenAlex
- W2023454634
- Cited by
- 32
- References
- 68
- Citations by year
- 2024: 1 · 2023: 1 · 2019: 2 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Archives of Disease in Childhood Fetal & Neonatal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- antioxidants, neonatal lung disease, CD28 costimulation, AP-1, adenoviral E1A, histone H4 acetylation, RNA polymerase II, T cell activation
- MeSH terms
- Antioxidants, Chronic Disease, Free Radicals, Humans, Infant, Newborn, Infant, Premature, Lung Diseases, Reactive Oxygen Species
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antioxidants in neonatal lung disease. https://app.cochat.ai/papers/10.1136/fn.73.2.f112
- The paper
- Fardy, C. H., & Silverman, M. (1995). Antioxidants in neonatal lung disease. Archives of Disease in Childhood - Fetal and Neonatal Edition. https://doi.org/10.1136/fn.73.2.f112
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.