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Cited by 74Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesMicrobial metabolism and enzyme function

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Impaired acetaldehyde oxidation in alcoholics

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Palmer, K R, Jenkins, W J·1982·Gut
DOI 10.1136/gut.23.9.729PMC PMC1419765
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Abstract

High blood acetaldehyde levels in alcoholics after ethanol ingestion are due to reduced acetaldehyde oxidation rather than to an increased rate of its formation from ethanol. This is associated with low hepatic acetaldehyde dehydrogenase activity in alcoholic subjects and may represent a specific abnormality in them.

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Crossref · 10.1136/gut.23.9.729

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Research works printed but not linked: 30

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Metadata

Authors
Palmer, K. R., & Jenkins, W. J.
Affiliations
The Royal Free Hospital (GB)
Venue
Gut
Publisher
BMJ
Published
1982-09
Volume
23
Issue
9
Pages
729-733
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
DOI
10.1136/gut.23.9.729
PMC
PMC1419765
OpenAlex
W2131522170
Cited by
74
References
0
Citations by year
2025: 1 · 2024: 1 · 2021: 1 · 2017: 2 · 2016: 2 · 2015: 1 · 2013: 1 · 2012: 1
FWCI
9.33
Type
journal article
Language
en
Open access
Locations
  • Gut (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial metabolism and enzyme function
Keywords
acetaldehyde oxidation, alcoholism, acetaldehyde dehydrogenase, hepatic enzyme activity, alcohol metabolism
MeSH terms
Acetaldehyde, Adult, Ethanol, Alcoholism, Aldehyde Oxidoreductases, Humans, Lactates, Liver, Male, Middle Aged, Pyruvates, Pyruvic Acid, Lactic Acid

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