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Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria.
Open accessAbstract
Recent evidence indicates that ileal Peyer's patches represent the main infection route for Yersinia enterocolitica. In this study transmission and scanning electron microscopy have shown that only a small fraction of bacteria present in the lumen adhere to the follicle-associated murine epithelium with no discernible preference for either M or absorptive cells. Yersiniae attached to M cells are phagocytosed and transported from the lumen into the lamina propria. No invasion of columnar absorptive cells was observed. These data, in combination with recently published reports, indicate that the involvement of M cells is a common step in bacterial invasion of Peyer's patches.
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Citations
Cited by
Monocyte-Mediated Defense Against Microbial Pathogens
Serbina, N. V., Jia, T., Hohl, T. M., & Pamer, E. G. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090326 · Cited by 1,123
ANTIGEN SAMPLING ACROSS EPITHELIAL BARRIERS AND INDUCTION OF MUCOSAL IMMUNE RESPONSES
Neutra, M. R., Pringault, E., & Kraehenbuhl, J.-P. (1996) · Annual Review of Immunology · doi:10.1146/annurev.immunol.14.1.275 · Cited by 474
Microparticle targeting to M cells
Ermak, T. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(98)00043-x · Cited by 75
Interferon Consensus Sequence Binding Protein Confers Resistance against Yersinia enterocolitica
Hein, J., Kempf, V. A. J., Diebold, J., Bücheler, N., Preger, S., Horak, I., Sing, A., Kramer, U., & Autenrieth, I. B. (2000) · Infection and Immunity · doi:10.1128/iai.68.3.1408-1417.2000 · Cited by 39
Freund, S., Czech, B., Trülzsch, K., Ackermann, N., & Heesemann, J. (2008) · Journal of Bacteriology · doi:10.1128/jb.00156-08 · Cited by 31
Metadata
- Authors
- Grützkau, A., Hanski, C., Hahn, H., & Riecken, E. O.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1990-09
- Volume
- 31
- Issue
- 9
- Pages
- 1011-1015
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2100265489
- Cited by
- 265
- References
- 0
- FWCI
- 5.36
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria. https://app.cochat.ai/papers/10.1136/gut.31.9.1011
- The paper
- Grützkau, A., Hanski, C., Hahn, H., & Riecken, E. O. (1990). Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria. Gut. https://doi.org/10.1136/gut.31.9.1011
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.