Cited by 2,440Gastrointestinal motility and disordersPsychosomatic Disorders and Their TreatmentsGastroesophageal reflux and treatments

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Functional bowel disorders and functional abdominal pain

Open access

Thompson, W G, Longstreth, G F, Drossman, D A, Heaton, K W, Irvine, E J, Müller-Lissner, S A·1999·Gut

DOI 10.1136/gut.45.2008.ii43PMC PMC1766683

Open this paper in CoChat — free account Open PDF

Abstract

The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results. The terminology was clarified and the diagnostic criteria and management recommendations were revised. A functional bowel disorder (FBD) is diagnosed by characteristic symptoms for at least 12 weeks during the preceding 12 months in the absence of a structural or biochemical explanation. The irritable bowel syndrome, functional abdominal bloating, functional constipation, and functional diarrhea are distinguished by symptom-based diagnostic criteria. Unspecified FBD lacks criteria for the other FBDs. Diagnostic testing is individualized, depending on patient age, primary symptom characteristics, and other clinical and laboratory features. Functional abdominal pain (FAP) is defined as either the FAP syndrome, which requires at least six months of pain with poor relation to gut function and loss of daily activities, or unspecified FAP, which lacks criteria for the FAP syndrome. An organic cause for the pain must be excluded, but aspects of the patient’s pain behavior are of primary importance. Treatment of the FBDs relies upon confident diagnosis, explanation, and reassurance. Diet alteration, drug treatment, and psychotherapy may be beneficial, depending on the symptoms and psychological features.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1136/gut.45.2008.ii43

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

U. S. Householder survey of functional gastrointestinal disorders: Prevalence, sociodemography, and health impact
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Grant Thompson, W., Whitehead, W. E., Janssens, J., Funch-Jensen, P., Corazziari, E., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01303162 · Cited by 2,198
Self-citation
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
Self-citation
Defecation frequency and timing, and stool form in the general population: a prospective study.
Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E., & Hughes, A. O. (1992) · Gut · doi:10.1136/gut.33.6.818 · Cited by 733
Self-citation
Irritable bowel syndrome: A technical review for practice guideline development
Drossman, D. A., Whitehead, W. E., & Camilleri, M. (1997) · Gastroenterology · doi:10.1053/gast.1997.v112.agast972120 · Cited by 571
Self-citation
Detection of pseudodiarrhoea by simple clinical assessment of intestinal transit rate.
O'Donnell, L. J. D., Virjee, J., & Heaton, K. (1990) · British medical journal · doi:10.1136/bmj.300.6722.439 · Cited by 537
Self-citation
A Comparison of Symptoms after the Consumption of Milk or Lactose-Hydrolyzed Milk by People with Self-Reported Severe Lactose Intolerance
Suarez, F. L., Savaiano, D. A., & Levitt, M. D. (1995) · New England Journal of Medicine · doi:10.1056/nejm199507063330101 · Cited by 508
THE IRRITABLE COLON SYNDROME
Chaudhary, N. A., & Truelove, S. C. (1962) · QJM · doi:10.1093/oxfordjournals.qjmed.a066971 · Cited by 498
Medical costs in community subjects with irritable bowel syndrome
Talley, N. J., Gabriel, S. E., Harmsen, W. S., Zinsmeister, A. R., & Evans, R. W. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90738-6 · Cited by 460 · cited 1×
“5 It accounts for high direct medical expenses 6 and indirect costs, including absenteeism from work.”
Background
A longitudinal survey of self-reported bowel habits in the United States
Everhart, J. E., Go, V. L. W., Johannes, R. S., FitzSimmons, S. C., Roth, H. P., & White, L. R. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01537261 · Cited by 384
A diagnostic score for the irritable bowel syndrome. Its value in the exclusion of organic disease.
Kruis, W., Thieme, C., Weinzierl, M., Schüßler, P., Holl, J., & Paulus, W. J. (1984) · PubMed · Cited by 318

Show all 36 references

Sorted by citations

Items 801–900 of 1,017

Clinical, physiological and radiological assessment of rectovaginal septum reinforcement with mesh for complex rectocele
D’Hoore, A. J. L., Vanbeckevoort, D., & PENNINCKX, F. M. (2008) · British journal of surgery · doi:10.1002/bjs.6322 · Cited by 59
Is There an Association Between GNβ3–C825T Genotype and Lower Functional Gastrointestinal Disorders?
Andresen, V., Camilleri, M., Kim, H. J., Stephens, D. A., Carlson, P. J., Talley, N. J., Saito, Y. A., Urrutia, R. A., & Zinsmeister, A. R. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.017 · Cited by 59
Predictive factors for compliance with transanal irrigation for the treatment of defecation disorders
Bildstein, C., Melchior, C., Gourcerol, G., Boueyre, E., Bridoux, V., Vérin, É., & Leroi, A. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i11.2029 · Cited by 59
Rationale for using serotonergic agents to treat irritable bowel syndrome
Baker, D. E. (2005) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/62.7.700 · Cited by 59
Do male sex hormones protect from irritable bowel syndrome?
Houghton, L. A., Jackson, N. A., Whorwell, P. J., & Morris, J. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02314.x · Cited by 59
Clinical Pharmacokinetics of Tegaserod, a Serotonin 5-HT4 Receptor Partial Agonist with Promotile Activity
Appel‐Dingemanse, S. (2002) · Clinical Pharmacokinetics · doi:10.2165/00003088-200241130-00002 · Cited by 59
Subjective Health Complaints and Modern Health Worries in Patients with Subjective Food Hypersensitivity
Lind, R., Arslan, G., Eriksen, H. R., Kahrs, G., Haug, T. T., Florvaag, E., & Berstad, A. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2767-6 · Cited by 58
Role of negative affects in pathophysiology and clinical expression of irritable bowel syndrome
Muscatello, M. R. A. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i24.7570 · Cited by 61
Effect of composite yogurt enriched with acacia fiber andBifidobacterium lactis
Min, Y. W. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i33.4563 · Cited by 60
Insights Into Normal and Disordered Bowel Habits From Bowel Diaries
Bharucha, A. E., Seide, B. M., Zinsmeister, A. R., & Melton, L. J. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01631.x · Cited by 58
Gastric distension and duodenal lipid infusion modulate intestinal gas transit and tolerance in humans
Serra, J., Azpiroz, F., & Malagelada, J. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05976.x · Cited by 58
Electro-acupuncture attenuates stress-induced defecation in rats with chronic visceral hypersensitivity via serotonergic pathway
Tian, X. Y., Bian, Z. X., Hu, X. G., Zhang, X. J., Liu, L., & Zhang, H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.03.014 · Cited by 58
Linaclotide: A novel agent for chronic constipation and irritable bowel syndrome
Love, B. L., Johnson, A., & Smith, L. S. (2014) · American Journal of Health-System Pharmacy · doi:10.2146/ajhp130575 · Cited by 58
New therapeutic perspectives in irritable bowel syndrome: Targeting low-grade inflammation, immuno-neuroendocrine axis, motility, secretion and beyond
Sinagra, E., Morreale, G. C., Mohammadian, G., Fusco, G., Guarnotta, V., Tomasello, G., Cappello, F., Rossi, F., Amvrosiadis, G., & Raimondo, D. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i36.6593 · Cited by 64
Treating irritable bowel syndrome with probiotics: the evidence
Parkes, G. C., Sanderson, J. D., & Whelan, K. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s002966511000011x · Cited by 57
Rectal hyposensitivity: pathophysiological mechanisms
Gladman, M. A., Aziz, Q., Scott, S. M., Williams, N. S., & Lunniss, P. J. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01216.x · Cited by 57
Gender Role in Irritable Bowel Syndrome: A Comparison of Irritable Bowel Syndrome Module (ROME III) Between Male and Female Patients
Anbardan, S. J., Daryani, N. E., Fereshtehnejad, S., Vakili, S. T. T., Keramati, M. R., & Ajdarkosh, H. (2012) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2012.18.1.70 · Cited by 57
TREATMENT FOR IRRITABLE BOWEL SYNDROME
Hadley, S. K., & Gaarder, S. M. (1980) · Inpharma Weekly · doi:10.1007/bf03290989 · Cited by 57
Acute exacerbation of pain in irritable bowel syndrome: efficacy of phloroglucinol/trimethylphloroglucinol – a randomized, double‐blind, placebo‐controlled study
Chassany, O., Bonaz, B. L., Varannes, S. B. D., Bueno, L. P., Cargill, G. A., Coffin, B., Ducrotte, P. R., & Grange, V. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03296.x · Cited by 57
Interleukin-8 and SDF1-alpha mRNA expression in colonic biopsies from patients with inflammatory bowel disease
Katsuta, T., Lim, C., Shimoda, K., Shibuta, K., Mitra, P., Banner, B. F., Mori, M., & Barnard, G. F. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03289.x · Cited by 57
Contribution of Gender to Pathophysiology and Clinical Presentation of IBS: Should Management Be Different in Women?
Ouyang, A., & Wrzos, H. F. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00975.x · Cited by 57
Brain activation responses to subliminal or supraliminal rectal stimuli and to auditory stimuli in irritable bowel syndrome
Andresen, V., Bach, D. R., Poellinger, A., Tsrouya, C., Stroh, A., Förschler, A., Georgiewa, P., Zimmer, C., & Mönnikes, H. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00720.x · Cited by 57
Functional bowel symptoms in a general Dutch population and associations with common stimulants
Boekema, P. J. (2001) · The Netherlands Journal of Medicine · doi:10.1016/s0300-2977(01)00128-0 · Cited by 57
Visceral Hypersensitivity
Delgado-Aros, S., & Camilleri, M. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000156114.22598.1b · Cited by 58
Effect of sacral anterior root stimulator on bowel dysfunction in patients with spinal cord injury
Vallès, M., Rodríguez, A., Borau, A., & Mearin, F. (2009) · Diseases of the Colon & Rectum · doi:10.1007/dcr.0b013e31819ed459 · Cited by 56
Irritable Bowel Syndrome Is More Common in Women Regardless of the Menstrual Phase: A Rome II-based Survey
Lee, S., Kim, J. H., Sung, I., Park, H. S., Jin, C. J., Choe, W. H., Kwon, S. Y., Lee, C. H., & Choi, K. W. (2007) · Journal of Korean Medical Science · doi:10.3346/jkms.2007.22.5.851 · Cited by 56
Attention to pain words in irritable bowel syndrome: Increased orienting and speeded engagement
Chapman, S., & Martin, M. (2010) · British Journal of Health Psychology · doi:10.1348/135910710x505887 · Cited by 56
Colonic Responses to Gas Loads in Subgroups of Patients With Abdominal Bloating
Hernando-Harder, A. C., Serra, J., Azpiroz, F., Milà, M., Aguadé‐Bruix, S., Malagelada, C., Tremolaterra, F., Villòria, A., & Malagelada, J. (2010) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.75 · Cited by 56
Hypervigilance in irritable bowel syndrome compared with organic gastrointestinal disease
Posserud, I., Svedlund, J., Wallin, J., & Simrén, M. (2009) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2008.09.020 · Cited by 59
Comparative Study between Surgical and Non-surgical Treatment of Anismus in Patients with Symptoms of Obstructed Defecation: A Prospective Randomized Study
Faried, M., Nakeeb, A. E., Youssef, M., Omar, W., & Monem, H. A. E. (2010) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-010-1229-4 · Cited by 56
Water and fluid intake in the prevention and treatment of functional constipation in children and adolescents: is there evidence?
Boilesen, S. N., Tahan, S., Dias, F. C., Melli, L. C. F. L., & de Morais, M. B. (2017) · Jornal de Pediatria · doi:10.1016/j.jped.2017.01.005 · Cited by 56
Assessment of somatoform disorders: a review of strategies and instruments
Hiller, W., & Janča, A. (2003) · Acta Neuropsychiatrica · doi:10.1034/j.1601-5215.2003.00031.x · Cited by 56
Ulcerative colitis: factors affecting difficulties of life and psychological well being of patients in remission
Tanaka, M., & Kazuma, K. (2005) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2004.00955.x · Cited by 56
Influence of body posture on intestinal transit of gas
Dainese, R., Serra, J., Azpiroz, F., & Malagelada, J. R. (2003) · Gut · doi:10.1136/gut.52.7.971 · Cited by 56
Incidence of Colonic Ischemia, Hospitalized Complications of Constipation, and Bowel Surgery in Relation To Use of Alosetron Hydrochloride
MILLER, D. P., Alfredson, T. D., Cook, S. F., Sands, B. E., & Walker, A. M. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07418.x · Cited by 56
Gain and loss of gastrointestinal symptoms in diabetes mellitus: associations with psychiatric disease, glycemic control, and autonomic neuropathy over 2 years of follow-up
Quan, C., Talley, N. J., Jones, M. P., Spies, J., & Horowitz, M. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2008.01943.x · Cited by 55
Role of antibiotic therapy on long‐term germ excretion in faeces and digestive symptoms after Salmonella infection
Barbara, Stanghellini, Berti‐Ceroni, Giorgio, D., Salvioli, Corradi, Cremon, & Corinaldesi (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00818.x · Cited by 55
Dietary fibre, fluids and physical activity in relation to constipation symptoms in pre-adolescent children
Jennings, A., Davies, G. J., Costarelli, V., & Dettmar, P. W. (2009) · Journal of Child Health Care · doi:10.1177/1367493509102469 · Cited by 55
Anal plugs and retrograde colonic irrigation are helpful in fecal incontinence or constipation
Cazemier, M., Felt-Bersma, R. J. F., & Mulder, C. J. J. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i22.3101 · Cited by 55
Laxative and Anti-diarrheal Activity of Polycarbophil in Mice and Rats
Saito, T., Mizutani, F., Iwanaga, Y., Morikawa, K., & Kato, H. (2002) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.89.133 · Cited by 55
Sensitivity Disturbances in Patients with Irritable Bowel Syndrome and Fibromyalgia
Caldarella, M. P., Giamberardino, M. A., Sacco, F., Affaitati, G., Milano, A., Lerza, R., Balatsinou, C., Laterza, F., Pierdomenico, S. D., Cuccurullo, F., et al. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00823.x · Cited by 55
Chronic constipation in hemiplegic patients
Bracci, F. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i29.3967 · Cited by 55
Discrepancies between Patient-Reported Outcomes and Clinician-Reported Outcomes in Chronic Venous Disease, Irritable Bowel Syndrome, and Peripheral Arterial Occlusive Disease
Chassany, O., Le-Jeunne, P., Duracinský, M., Schwalm, M.-S., & Mathieu, M. (2006) · Value in Health · doi:10.1111/j.1524-4733.2006.00079.x · Cited by 55
An extended assessment of bowel habits in a general population
Bassotti, G. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i5.713 · Cited by 55
Symptom clustering in subjects with and without diabetes mellitus a population-based study of 15,000 Australian adults
Hammer, J., Howell, S. C., Bytzer, P. M., Horowitz, M., & Talley, N. J. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07236.x · Cited by 55
Effects of alosetron on gastrointestinal transit time and rectal sensation in patients with irritable bowel syndrome
Thumshirn, Coulie, Camilleri, Zinsmeister, Burton, & Dyke, V. (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00786.x · Cited by 55
Clinical and physiological findings, and possible aetiological factors of rectal hyposensitivity
Gladman, M. A., Scott, S. M., Williams, N. S., & Lunniss, P. J. (2003) · British journal of surgery · doi:10.1002/bjs.4103 · Cited by 55
Development and initial validation of a measure of perceived stigma in irritable bowel syndrome
Jones, M. P., Keefer, L., Bratten, J. R., Taft, T., Crowell, M. D., Levy, R. L., & Palsson, O. S. (2009) · Psychology Health & Medicine · doi:10.1080/13548500902865956 · Cited by 54
Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome
Sabaté, J. M., Veyrac, M., Mion, F., Siproudhis, L., Ducrotte, P. R., Zerbib, F., Grimaud, J., Dapoigny, M. C., Dyard, F., & Coffin, B. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03759.x · Cited by 54
Brain‐derived neurotrophic factor accelerates gut motility in slow‐transit constipation
Chen, F., Yu, Y., Wang, P., Dong, Y., Wang, T., Zuo, X., & Li, Y. (2014) · Acta Physiologica · doi:10.1111/apha.12374 · Cited by 54
Consenso Latinoamericano de Estreñimiento Crónico
Wasserman, M. S., Francisconi, C. F. D. M., Olden, K. W., Aguilar-Paiz, L., Bustos-Fernández, L. M., Cohen, H., Passos, M. D. C. F., González-Martínez, M. A., Iade, B., Iantorno, G., et al. (2008) · Gastroenterología y Hepatología · doi:10.1157/13116072 · Cited by 54
Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial
Cheong, P. K., Ford, A. C., Cheung, C., Ching, J. Y., Chan, Y., Sung, J. J. �., Chan, F. K. L., & Wu, J. C. Y. (2018) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(18)30303-0 · Cited by 54
Mindfulness for irritable bowel syndrome: protocol development for a controlled clinical trial
Gaylord, S. A., Whitehead, W. E., Coble, R. S., Faurot, K. R., Palsson, O. S., Garland, E. L., Frey, W., & Mann, J. D. (2009) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-9-24 · Cited by 53
Síndrome del intestino irritable
Domingo, J. J. S. (2021) · Medicina Clínica · doi:10.1016/j.medcli.2021.04.029 · Cited by 53
Fluctuation of gastrointestinal symptoms in the community: a 10‐year longitudinal follow‐up study
Ford, A. C., Forman, D., Bailey, A. G., Axon, A. T. R., & Moayyedi, P. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03813.x · Cited by 53
Symptomatic Overlap Between Microscopic Colitis and Irritable Bowel Syndrome
Abboud, R., Pardi, D. S., Tremaine, W. J., Kammer, P. P., Sandborn, W. J., & Loftus, E. V. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e31827febfd · Cited by 53
Factors That Predict Relief From Upper Abdominal Pain After Cholecystectomy
Thistle, J. L., Longstreth, G. F., Romero, Y., Arora, A. S., Simonson, J. A., Diehl, N. N., Harmsen, W. S., & Zinsmeister, A. R. (2011) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2011.05.014 · Cited by 53
Self-citation
Analysis of the Gastrointestinal Symptoms of Uninvestigated Dyspepsia and Irritable Bowel Syndrome
Hori, K., Matsumoto, T., & Miwa, H. (2009) · Gut and Liver · doi:10.5009/gnl.2009.3.3.192 · Cited by 54
General geriatrics and gastroenterology: constipation and faecal incontinence
Müller-Lissner, S. A. (2002) · Best Practice & Research Clinical Gastroenterology · doi:10.1053/bega.2002.0269 · Cited by 53
Self-citation
Bowel Habit Reference Values and Abnormalities in Young Iranian Healthy Adults
Adibi, P., Behzad, E., Pirzadeh, S., & Mohseni, M. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9509-2 · Cited by 53
Efficacy and safety of acupuncture for functional constipation: a randomised, sham-controlled pilot trial
Lee, H.-Y., Kwon, O.-J., Kim, J., Kim, A., Kim, A.-R., Park, H., Cho, J.-H., Kim, J.-H., & Choi, S. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2243-4 · Cited by 53
Reflex control of intestinal gas dynamics and tolerance in humans
Harder, H., Serra, J., Azpiroz, F., & Malagelada, J. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00174.2003 · Cited by 53
Advances in clinical laboratory tests for inflammatory bowel disease
Nakamura, R. M., Matsutani, M., & Barry, M. J. (2003) · Clinica Chimica Acta · doi:10.1016/s0009-8981(03)00286-9 · Cited by 53
Toward a definition of colonic inertia
Bassotti, G. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i17.2465 · Cited by 53
Panic disorder associated with gastrointestinal disease: Review and hypotheses
Maunder, R. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(97)00133-5 · Cited by 53
Effect of Breadmaking Process on In Vitro Gut Microbiota Parameters in Irritable Bowel Syndrome
Costabile, A., Santarelli, S., Claus, S. P., Sanderson, J., Hudspith, B. N., Brostoff, J., Ward, J. L., Lovegrove, A., Shewry, P. R., Jones, H. E., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111225 · Cited by 52
Systematic review of diagnostic criteria for IBS demonstrates poor validity and utilization of Rome III
Dang, J. C., Ardila‐Hani, A., Amichai, M. M., Chua, K., & Pimentel, M. (2012) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2012.01943.x · Cited by 52
Experiences of abdominal massage for constipation
Lämås, K., Graneheim, U. H., & Jacobsson, C. (2011) · Journal of Clinical Nursing · doi:10.1111/j.1365-2702.2011.03946.x · Cited by 52
The features of adolescent irritable bowel syndrome in Japan
Endo, Y., Shoji, T., Fukudo, S., 町田, 知., Machida, T., Noda, S., & Hongo, M. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06637.x · Cited by 52
IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population
Ligaarden, S. C., Lydersen, S., & Farup, P. G. (2012) · BMC Gastroenterology · doi:10.1186/1471-230x-12-166 · Cited by 52
The Effect of Oral α-Galactosidase on Intestinal Gas Production and Gas-Related Symptoms
Stefano, M. D., Miceli, E., Gotti, S., Missanelli, A., Mazzocchi, S., & Corazza, G. R. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9296-9 · Cited by 55
The Effects of Melatonin on Colonic Transit Time in Normal Controls and IBS Patients
Lu, W.-Z., Song, G., Gwee, K., & Ho, K. Y. (2008) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0463-z · Cited by 52
Reduced E‐cadherin expression is associated with abdominal pain and symptom duration in a study of alternating and diarrhea predominant IBS
Wilcz-Villega, E., McClean, S., & O'Sullivan, M. (2014) · Neurogastroenterology and Motility · doi:10.1111/nmo.12262 · Cited by 52
A Randomized, Controlled, Crossover Study of Sacral Nerve Stimulation for Irritable Bowel Syndrome
Fassov, J., Lundby, L., Laurberg, S., Buntzen, S., & Krogh, K. (2014) · Annals of Surgery · doi:10.1097/sla.0000000000000559 · Cited by 52
Innervation of enteric mast cells by primary spinal afferents in guinea pig and human small intestine
Wang, G., Wang, X.-Y., Liu, S., Qu, M., Xia, Y. L., NEEDLEMAN, B. J., Mikami, D. J., & Wood, J. D. (2014) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00125.2014 · Cited by 52
Frequency of irritable bowel syndrome in college students.
Jafri, W., Yakoob, J., Jafri, N., Islam, S., & Ali, Q. M. (2005) · PubMed · Cited by 52
Pilot study of the efficacy of renzapride on gastrointestinal motility and symptoms in patients with constipation‐predominant irritable bowel syndrome
Tack, J. F., Middleton, S. J., HORNE, M. C., Piessevaux, H. H., Bloor, J., Meyers, N. L., & PALMER, R. M. J. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02940.x · Cited by 52
Long-Term Outcome of Functional Childhood Constipation
Khan, S., Campo, J. V., Bridge, J. A., Chiappetta, L., Wald, A. M., & di Lorenzo, C. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9308-9 · Cited by 52
Effect of gluten-free diet and co-morbidity of irritable bowel syndrome-type symptoms on health-related quality of life in adult coeliac patients
Usai, P., Manca, R., Cuomo, R., Lai, M., & Mf, B. (2007) · Digestive and Liver Disease · doi:10.1016/j.dld.2007.05.017 · Cited by 52
Rectal Function and Bowel Habit in Irritable Bowel Syndrome
Distrutti, E., Salvioli, B., Azpiroz, F., & Malagelada, J. R. (2004) · The American Journal of Gastroenterology · doi:10.1046/j.1572-0241.2003.04012.x · Cited by 52
Effect of cholecystectomy on bowel function: a prospective, controlled study
Hearing, S. D., Thomas, L. A., Heaton, K. W., & Hunt, L. P. (1999) · Gut · doi:10.1136/gut.45.6.889 · Cited by 52
Self-citation
The Clinical Course of Postinfectious Irritable Bowel Syndrome
Jung, I. S., Kim, H. S., Park, H., & Lee, S. I. (2009) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e31818c87d7 · Cited by 51
Chronic fatigue syndrome 5 years after giardiasis: differential diagnoses, characteristics and natural course
Mørch, K., Hanevik, K., Rivenes, A. C., Bødtker, J. E., Næss, H., Stubhaug, B., Wensaas, K., Rørtveit, G., Eide, G. E., Hausken, T., et al. (2013) · BMC Gastroenterology · doi:10.1186/1471-230x-13-28 · Cited by 51
Prevalence of organic colonic lesions in patients meeting Rome III criteria for diagnosis of IBS: a prospective multi-center study utilizing colonoscopy
Ishihara, S., Yashima, K., Kushiyama, Y., Izumi, A., Kawashima, K., Fujishiro, H., Kojo, H., Komazawa, Y., Hamamoto, T., Yamamoto, T., et al. (2012) · Journal of Gastroenterology · doi:10.1007/s00535-012-0573-4 · Cited by 51
Small intestinal bacterial overgrowth is associated with irritable bowel syndrome and is independent of proton pump inhibitor usage
Giamarellos‐Bourboulis, E. J., Pyleris, E., Barbatzas, C., Pistiki, A. C., & Pimentel, M. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0484-6 · Cited by 51
Development of Functional Diarrhea, Constipation, Irritable Bowel Syndrome, and Dyspepsia During and After Traveling Outside the USA
Tuteja, A. K., Talley, N. J., Gelman, S. S., Adler, S. C., Thompson, C. M., Tolman, K., & Hale, D. C. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-007-9853-x · Cited by 51
Disturbances of Motility and Visceral Hypersensitivity in Irritable Bowel Syndrome: Biological Markers or Epiphenomenon
Quigley, E. M. M. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.010 · Cited by 52
Intestinal Gas and Bloating: Effect of Prokinetic Stimulation
Accarino, A. M., Pérez, F., Azpiroz, F., Quiroga, S., & Malagelada, J. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2008.01866.x · Cited by 51
Changes in Bowel Function: Pregnancy and the Puerperium
Derbyshire, E. J., Davies, J., & Dettmar, P. W. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9538-x · Cited by 51
Comparison of breath testing with fructose and high fructose corn syrups in health and IBS
Skoog, S. M., Bharucha, A. E., & Zinsmeister, A. R. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.01074.x · Cited by 51
Hypersensitivity to cutaneous thermal nociceptive stimuli in irritable bowel syndrome
Rodrigues, A. C., Verne, N. G., Schmidt, S. O., & Mauderli, A. P. (2005) · Pain · doi:10.1016/j.pain.2005.01.023 · Cited by 51
The puborectalis muscle
Azpiroz, F., Fernández‐Fraga, X., Merletti, R., & Enck, P. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00663.x · Cited by 51
Relationship between Irritable Bowel Syndrome, Worry and Stress in Adolescent Girls
Song, S.-W., Park, S., Kim, S., & Kang, S. G. (2012) · Journal of Korean Medical Science · doi:10.3346/jkms.2012.27.11.1398 · Cited by 51
Gender distribution in irritable bowel syndrome is proportional to the severity of constipation relative to diarrhea
Herman, J. R., Pokkunuri, V. B., Braham, L., & Pimentel, M. (2010) · Gender Medicine · doi:10.1016/j.genm.2010.06.007 · Cited by 50
Activation of lamina I spinal cord neurons that express the substance P receptor in visceral nociception and hyperalgesia
Honoré, P., Kamp, E. H., Rogers, S. D., Gebhart, G. F., & Mantyh, P. W. (2002) · Journal of Pain · doi:10.1054/jpai.2002.27001 · Cited by 50
International bowel function extended spinal cord injury data set
Krogh, K., Perkash, I., Stiens, S. A., & Biering‐Sørensen, F. (2008) · Spinal Cord · doi:10.1038/sc.2008.103 · Cited by 50
Predictors of subjective fatigue in chronic gastrointestinal disease
Simrén, M., Svedlund, J., Posserud, I., Bjornsson, E. S., & Abrahamsson, H. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03770.x · Cited by 50
Twenty-four-hour manometric study of colonic propulsive activity in patients with diarrhea due to inflammatory (ulcerative colitis) and non-inflammatory (irritable bowel syndrome) conditions
Bassotti, G., de Roberto, G., Chistolini, F., Sietchiping-Nzepa, F., Morelli, O., & Morelli, A. (2004) · International Journal of Colorectal Disease · doi:10.1007/s00384-004-0604-6 · Cited by 50
Indications of ‘atopic bowel’ in patients with self‐reported food hypersensitivity
Lillestøl, K., Helgeland, L., Lied, G. A., Florvaag, E., Valeur, J., Lind, R. A., & Berstad, A. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04261.x · Cited by 50
Diet in subjects with irritable bowel syndrome: A cross-sectional study in the general population
Ligaarden, S. C., Lydersen, S., & Farup, P. G. (2012) · BMC Gastroenterology · doi:10.1186/1471-230x-12-61 · Cited by 50

Authors: Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A.
Affiliations: Kaiser Permanente (US)
Corresponding author: Thompson, W G
ORCID: Thompson, W G
Longstreth, G F
Drossman, D A
Venue: Gut
Publisher: BMJ
Published: 1999-09-01
Volume: 45
Issue: suppl 2
Pages: II43-II47
ISSN: 0017-5749 (ISSN-L)
1468-3288
DOI: 10.1136/gut.45.2008.ii43
PMC: PMC1766683
OpenAlex: W2166386674
Semantic Scholar: 9e1a4a0b207039b5d64277278fb3532bc6348472
Cited by: 2,440
References: 36
Citations by year: 2026: 11 · 2025: 20 · 2024: 18 · 2023: 38 · 2022: 28 · 2021: 47 · 2020: 36 · 2019: 30 · 2018: 47 · 2017: 43 · 2016: 64 · 2015: 77 · 2014: 81 · 2013: 92 · 2012: 123
FWCI: 64.06
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Gut (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
HighWire Press Open Archive (submittedVersion)
UNC Libraries
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
Keywords: functional bowel disorders, functional abdominal pain, irritable bowel syndrome, functional constipation, functional diarrhea, diagnostic criteria revision, treatment guidelines, pain behavior, dietary change, psychotherapy, pharmacotherapy
MeSH terms: Colonic Diseases, Functional, Constipation, Diarrhea, Gastrointestinal Diseases, Humans, Abdominal Pain

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Functional bowel disorders and functional abdominal pain

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks