Cited by 2,440Gastrointestinal motility and disordersPsychosomatic Disorders and Their TreatmentsGastroesophageal reflux and treatments

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Functional bowel disorders and functional abdominal pain

Open access

Thompson, W G, Longstreth, G F, Drossman, D A, Heaton, K W, Irvine, E J, Müller-Lissner, S A·1999·Gut

DOI 10.1136/gut.45.2008.ii43PMC PMC1766683

Open this paper in CoChat — free account Open PDF

Abstract

The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from multinational expert reviewers, was used to revise the diagnostic criteria and update diagnosis and treatment recommendations, based on research results. The terminology was clarified and the diagnostic criteria and management recommendations were revised. A functional bowel disorder (FBD) is diagnosed by characteristic symptoms for at least 12 weeks during the preceding 12 months in the absence of a structural or biochemical explanation. The irritable bowel syndrome, functional abdominal bloating, functional constipation, and functional diarrhea are distinguished by symptom-based diagnostic criteria. Unspecified FBD lacks criteria for the other FBDs. Diagnostic testing is individualized, depending on patient age, primary symptom characteristics, and other clinical and laboratory features. Functional abdominal pain (FAP) is defined as either the FAP syndrome, which requires at least six months of pain with poor relation to gut function and loss of daily activities, or unspecified FAP, which lacks criteria for the FAP syndrome. An organic cause for the pain must be excluded, but aspects of the patient’s pain behavior are of primary importance. Treatment of the FBDs relies upon confident diagnosis, explanation, and reassurance. Diet alteration, drug treatment, and psychotherapy may be beneficial, depending on the symptoms and psychological features.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1136/gut.45.2008.ii43

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

U. S. Householder survey of functional gastrointestinal disorders: Prevalence, sociodemography, and health impact
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Grant Thompson, W., Whitehead, W. E., Janssens, J., Funch-Jensen, P., Corazziari, E., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01303162 · Cited by 2,198
Self-citation
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
Self-citation
Defecation frequency and timing, and stool form in the general population: a prospective study.
Heaton, K. W., Radvan, J., Cripps, H., Mountford, R. A., Braddon, F. E., & Hughes, A. O. (1992) · Gut · doi:10.1136/gut.33.6.818 · Cited by 733
Self-citation
Irritable bowel syndrome: A technical review for practice guideline development
Drossman, D. A., Whitehead, W. E., & Camilleri, M. (1997) · Gastroenterology · doi:10.1053/gast.1997.v112.agast972120 · Cited by 571
Self-citation
Detection of pseudodiarrhoea by simple clinical assessment of intestinal transit rate.
O'Donnell, L. J. D., Virjee, J., & Heaton, K. (1990) · British medical journal · doi:10.1136/bmj.300.6722.439 · Cited by 537
Self-citation
A Comparison of Symptoms after the Consumption of Milk or Lactose-Hydrolyzed Milk by People with Self-Reported Severe Lactose Intolerance
Suarez, F. L., Savaiano, D. A., & Levitt, M. D. (1995) · New England Journal of Medicine · doi:10.1056/nejm199507063330101 · Cited by 508
THE IRRITABLE COLON SYNDROME
Chaudhary, N. A., & Truelove, S. C. (1962) · QJM · doi:10.1093/oxfordjournals.qjmed.a066971 · Cited by 498
Medical costs in community subjects with irritable bowel syndrome
Talley, N. J., Gabriel, S. E., Harmsen, W. S., Zinsmeister, A. R., & Evans, R. W. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90738-6 · Cited by 460 · cited 1×
“5 It accounts for high direct medical expenses 6 and indirect costs, including absenteeism from work.”
Background
A longitudinal survey of self-reported bowel habits in the United States
Everhart, J. E., Go, V. L. W., Johannes, R. S., FitzSimmons, S. C., Roth, H. P., & White, L. R. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01537261 · Cited by 384
A diagnostic score for the irritable bowel syndrome. Its value in the exclusion of organic disease.
Kruis, W., Thieme, C., Weinzierl, M., Schüßler, P., Holl, J., & Paulus, W. J. (1984) · PubMed · Cited by 318

Flagged first, then by citations

Show all 36 references

Sorted by citations

Items 401–500 of 1,017

Alterations in Expression of p11 and SERT in Mucosal Biopsy Specimens of Patients With Irritable Bowel Syndrome
Camilleri, M., Andrews, C. N., Bharucha, A. E., Carlson, P. J., Ferber, I. J., Stephens, D. A., Smyrk, T. C., Urrutia, R. A., Aerssens, J., Thielemans, L. A., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.11.020 · Cited by 127
Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype
Belmonte, L., Beutheu Youmba, S., Bertiaux-Vandaële, N., Antonietti, M., Lecleire, S., Zalar, A., Gourcerol, G., Leroi, A.-M., Déchelotte, P., Coëffier, M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042777 · Cited by 126
Significance of pelvic floor muscles in anal incontinence
Fernández‐Fraga, X., Azpiroz, F., & Malagelada, J. (2002) · Gastroenterology · doi:10.1053/gast.2002.36586 · Cited by 126
A double-blind placebo-controlled trial to study therapeutic effects of probiotic Escherichia coli Nissle 1917 in subgroups of patients with irritable bowel syndrome
Kruis, W., Chrubasik, S., Boehm, S., Stange, C., & Schulze, J. (2011) · International Journal of Colorectal Disease · doi:10.1007/s00384-011-1363-9 · Cited by 127
A Combination of Rifaximin and Neomycin Is Most Effective in Treating Irritable Bowel Syndrome Patients With Methane on Lactulose Breath Test
Low, K., Hwang, L., Hua, J., Zhu, A., Morales, W., & Pimentel, M. (2010) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3181c64c90 · Cited by 125
Twenty-four hour recordings of colonic motility in patients with diverticular disease
Bassotti, G., Battaglia, E., Spinozzi, F., Pelli, M. A., & Tonini, M. (2001) · Diseases of the Colon & Rectum · doi:10.1007/bf02234460 · Cited by 125
Outcomes of Stapled Transanal Rectal Resection vs . Biofeedback for the Treatment of Outlet Obstruction Associated with Rectal Intussusception and Rectocele: A Multicenter, Randomized, Controlled Trial
Lehur, P., Stuto, A., Fantoli, M., Villani, R. D., Queralto, M., Lazorthes, F., Hershman, M. J., Carriero, A., Pigot, F., Meurette, G., et al. (2008) · Diseases of the Colon & Rectum · doi:10.1007/s10350-008-9378-1 · Cited by 125
A Very Low-Carbohydrate Diet Improves Symptoms and Quality of Life in Diarrhea-Predominant Irritable Bowel Syndrome
Austin, G. L., Dalton, C. B., Hu, Y., Morris, C. B., Hankins, J. S., Weinland, S. R., Westman, E. C., Yancy, W. S., & Drossman, D. A. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.02.023 · Cited by 125
Self-citation
Rectal Hyposensitivity
Gladman, M. A., Scott, S. M., Chan, C. L. H., Williams, N. S., & Lunniss, P. J. (2003) · Diseases of the Colon & Rectum · doi:10.1007/s10350-004-6529-x · Cited by 125
Tegaserod, a 5‐HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects
Coffin, B., Farmachidi, J.-P., Rueegg, P. C., Bastie, A., & Bouhassira, D. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01449.x · Cited by 125
Characteristics of patients with irritable bowel syndrome recruited from three sources: implications for clinical trials
Longstreth, G. F., Hawkey, C. J., Mayer, E. A., Jones, R. H., Naesdal, J., Wilson, I. K., Peacock, R. A., & Wiklund, I. K. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01010.x · Cited by 124
Self-citation
Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome
Aerssens, J., Camilleri, M., Talloen, W., Thielemans, L., Göhlmann, H. W. H., Van den Wyngaert, I., Thielemans, T., De Hoogt, R., Andrews, C. N., Bharucha, A. E., et al. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2007.11.012 · Cited by 124
Increased prevalence of irritable bowel syndrome in patients with bronchial asthma
Roussos, A., Koursarakos, P., PATSOPOULOS, D., Gerogianni, I., & Philippou, N. (2003) · Respiratory Medicine · doi:10.1053/rmed.2001.1409 · Cited by 124
The Road to Rome
Thompson, W. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.011 · Cited by 124
Self-citation
A mixture of Escherichia coli (DSM 17252) and Enterococcus faecalis (DSM 16440) for treatment of the irritable bowel syndrome – A randomized controlled trial with primary care physicians
Enck, P., Zimmermann, K., Menke, G., Müller-Lissner, S. A., Martens, U., & Klosterhalfen, S. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01156.x · Cited by 124
Self-citation
Long-Term Study on the Effects of Visual Biofeedback and Muscle Training as a Therapeutic Modality in Pelvic Floor Dyssynergia and Slow-Transit Constipation
Battaglia, E., Serra, A. M., Buonafede, G., Dughera, L., Chistolini, F., Morelli, A., Emanuelli, G., & Bassotti, G. (2004) · Diseases of the Colon & Rectum · doi:10.1007/s10350-003-0010-0 · Cited by 124
Risk factors for gastro‐oesophageal reflux disease symptoms: a community study
Mohammed, I., Nightingale, P., & Trudgill, N. J. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02426.x · Cited by 124
Disordered eating practices in gastrointestinal disorders
Satherley, R., Howard, R. A., & Higgs, S. (2014) · Appetite · doi:10.1016/j.appet.2014.10.006 · Cited by 123
Intestinal Microbiota and its Role in Irritable Bowel Syndrome (IBS)
Öhman, L., & Simrén, M. (2013) · Current Gastroenterology Reports · doi:10.1007/s11894-013-0323-7 · Cited by 126
Constipation:
Rao, S. S. C. (2003) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(03)00026-8 · Cited by 123
Prucalopride Is Effective in Patients with Severe Chronic Constipation in Whom Laxatives Fail to Provide Adequate Relief
Coremans, G., Kerstens, R., Pauw, M. D., & Stevens, M. (2003) · Digestion · doi:10.1159/000070202 · Cited by 123
Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervation
Emmanuel, A. V., & Kamm, M. A. (2001) · Gut · doi:10.1136/gut.49.2.214 · Cited by 123
Abdominal Distention Results From Caudo-ventral Redistribution of Contents
Accarino, A. M., Pérez, F., Azpiroz, F., Quiroga, S., & Malagelada, J. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.01.067 · Cited by 122
Sacral Nerve Stimulation in Patients with Severe Constipation
Holzer, B., Rosén, H., Novi, G., Ausch, C., Hölbling, N., Hofmann, M., & Schiessel, R. (2008) · Diseases of the Colon & Rectum · doi:10.1007/s10350-007-9160-9 · Cited by 122
Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon‐gamma, severity of symptoms and psychiatric co‐morbidity
Fitzgerald, P., Eugene, M. C., Clarke, G. A., Scully, P., Barry, S., Eamonn, M. M. Q., Shanahan, F., Cryan, J. F., & Dinan, T. G. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01195.x · Cited by 122
Origin of gas retention and symptoms in patients with bloating
Salvioli, B., Serra, J., Azpiroz, F., Lorenzo‐Bosquet, C., Aguadé‐Bruix, S., Castell‐Conesa, J., & Malagelada, J. (2005) · Gastroenterology · doi:10.1053/j.gastro.2004.12.047 · Cited by 122
A technical review and clinical assessment of the wireless motility capsule.
Saad, R. J., & Hasler, W. L. (2011) · PubMed Central · Cited by 122
A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome
Blanchard, E. B., Lackner, J. M., Sanders, K., Krasner, S., Keefer, L., Payne, A., Gudleski, G. D., Katz, L., Rowell, D., Sykes, M., et al. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.07.003 · Cited by 121
Widespread hypersensitivity is related to altered pain inhibition processes in irritable bowel syndrome
Piché, M., Arsenault, M., Poitras, P., Rainville, P., & Bouin, M. (2009) · Pain · doi:10.1016/j.pain.2009.10.005 · Cited by 120
Symptoms and Physiology in Severe Chronic Constipation
Mertz, H., Naliboff, B. D., & Mayer, E. A. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.00783.x · Cited by 120
Differences in spinal distribution and neurochemical phenotype of colonic afferents in mouse and rat
Christianson, J. A., Traub, R. J., & Davis, B. M. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20816 · Cited by 120
An Outbreak of Acute Bacterial Gastroenteritis Is Associated With an Increased Incidence of Irritable Bowel Syndrome in Children
Thabane, M., Simunovic, M., Akhtar-Danesh, N., Garg, A. X., Clark, W. F., Collins, S. M., Salvadori, M., & Marshall, J. K. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2010.74 · Cited by 120
Pilot Study on the Effect of Linaclotide in Patients With Chronic Constipation
Johnston, J. M., Kurtz, C. B., Drossman, D. A., Lembo, A. J., Jeglinski, B. I., MacDougall, J. E., Antonelli, S. M., & Currie, M. G. (2008) · The American Journal of Gastroenterology · doi:10.1038/ajg.2008.59 · Cited by 119
Self-citation
Symptom Severity but Not Psychopathology Predicts Visceral Hypersensitivity in Irritable Bowel Syndrome
van der Veek, P. P. J., van Rood, Y. R., & Masclee, A. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2007.12.005 · Cited by 119
Cross‐talk and sensitization of bladder afferent nerves
Ustinova, E. E., Fraser, M. O., & Pezzone, M. A. (2009) · Neurourology and Urodynamics · doi:10.1002/nau.20817 · Cited by 119
Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome
Viramontes, B. E., Camilleri, M., McKinzie, S., Pardi, D. S., Burton, D. D., & Thomforde, G. M. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.04138.x · Cited by 119
Utility of red flag symptom exclusions in the diagnosis of irritable bowel syndrome
WHITEHEAD, W. E., PALSSON, O. S., FELD, A. D., LEVY, R. L., VON KORFF, M., TURNER, M. J., & DROSSMAN, D. A. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02956.x · Cited by 118
Self-citation
Alteration of the spinal modulation of nociceptive processing in patients with irritable bowel syndrome
Coffin, B., Bouhassira, D., Sabaté, J.-M., Barbe, L., & Jian, R. (2004) · Gut · doi:10.1136/gut.2003.031310 · Cited by 117
Chronic abdominal wall pain—A diagnostic challenge for the surgeon
Lindsetmo, R., & Stulberg, J. J. (2009) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2008.10.027 · Cited by 118
The role of fecal elastase-1 in detecting exocrine pancreatic disease
Leeds, J. S., Oppong, K. W., & Sanders, D. S. (2011) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2011.91 · Cited by 119
Comparison of the Rome IV and Rome III criteria for IBS diagnosis: A cross‐sectional survey
Bai, T., Xia, J., Jiang, Y., Cao, H., Zhao, Y., Zhang, L., Wang, H., Song, J., & Hou, X. (2016) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.13642 · Cited by 118
Genetic Influences in Irritable Bowel Syndrome: A Twin Study
Mohammed, I., Cherkas, L. F., Riley, S. A., Spector, T. D., & Trudgill, N. J. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.41700.x · Cited by 118
Effect of renzapride on transit in constipation-predominant irritable bowel syndrome
Camilleri, M., McKinzie, S., Fox, J., Foxx–Orenstein, A. E., Burton, D. D., Thomforde, G. M., Baxter, K. L., & Zinsmeister, A. R. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00391-x · Cited by 118
The role of methane in intestinal diseases
Roccarina, D., Lauritano, E. C., Gabrielli, M., Franceschi, F., Ojetti, V., & Gasbarrini, A. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2009.744 · Cited by 117
The effect of the 5‐HT3 receptor antagonist, alosetron, on brain responses to visceral stimulation in irritable bowel syndrome patients
Mayer, E. A., Berman, S. M., Derbyshire, S. W. G., Suyenobu, B. Y., Chang, L., Fitzgerald, L., Mandelkern, M. A., Hamm, L. R., Vogt, B. A., & Naliboff, B. D. (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01287.x · Cited by 117
A Randomized, Double-Blind, Placebo-Controlled Study to Assess Efficacy and Safety of 0.5 mg and 1 mg Alosetron in Women With Severe Diarrhea-predominant IBS
Krause, R. A., Ameen, V. Z., Gordon, S., West, M. A., Heath, A. T., Perschy, T. L., & Carter, E. G. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01282.x · Cited by 117
Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome
Giannini, E. G., Mansi, C., Dulbecco, P., & Savarino, V. (2006) · Nutrition · doi:10.1016/j.nut.2005.10.003 · Cited by 117
Obstructed defecation
D’Hoore, A., & PENNINCKX, F. M. (2003) · Colorectal Disease · doi:10.1046/j.1463-1318.2003.00497.x · Cited by 117
Prevalence and risk factors for peri- and postpartum urinary incontinence in primiparous women in China: a prospective longitudinal study
Zhu, L., Li, L., Lang, J., & Xu, T. (2012) · International Urogynecology Journal · doi:10.1007/s00192-011-1640-8 · Cited by 116
Irritable bowel syndrome: Novel views on the epidemiology and potential risk factors
Rey, E., & Talley, N. J. (2009) · Digestive and Liver Disease · doi:10.1016/j.dld.2009.07.005 · Cited by 115
Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women
Gonenne, J., Esfandyari, T., Camilleri, M., Burton, D. D., Stephens, D. A., Baxter, K. L., Zinsmeister, A. R., & Bharucha, A. E. (2006) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00808.x · Cited by 115
Hypnotherapy for irritable bowel syndrome: an audit of one thousand adult patients
Miller, V., Carruthers, H. R., Morris, J., Hasan, S. S., Archbold, S., & Whorwell, P. J. (2015) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13145 · Cited by 114
Bloating and Distention in Irritable Bowel Syndrome: The Role of Visceral Sensation
Agrawal, A., Houghton, L. A., Lea, R., Morris, J., Reilly, B., & Whorwell, P. J. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.02.096 · Cited by 114
Evaluation of the Irritable Bowel Syndrome Quality of Life (IBS-QOL) questionnaire in diarrheal-predominant irritable bowel syndrome patients
Andrae, D. A., Patrick, D. L., Drossman, D. A., & Covington, P. S. (2013) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-11-208 · Cited by 114
Self-citation
Do corticotropin releasing factor-1 receptors influence colonic transit and bowel function in women with irritable bowel syndrome?
Sweetser, S. R., Camilleri, M., Nord, S. L., Burton, D. D., Castenada, L., Croop, R. S., Tong, G., Dockens, R. C., & Zinsmeister, A. R. (2009) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00011.2009 · Cited by 114
Food hypersensitivity and irritable bowel syndrome
Zar, S., Kumar, D., & Benson, M. J. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.00951.x · Cited by 114
Irritable bowel syndrome subtypes according to bowel habit
Mearin, F., Balboa, A., Badia, X. C., Baró, E., Caldwell, E., Cucala, M., Díaz‐Rubio, M., Fueyo, A., Ponce, J. D. C., Roset, M., et al. (2003) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200302000-00010 · Cited by 114
Physical Activity and Intestinal Gas Clearance in Patients with Bloating
Villòria, A., Serra, J., Azpiroz, F., & Malagelada, J. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00873.x · Cited by 114
Ischemic colitis during treatment with alosetron
Friedel, D. M., Thomas, R. M., & Fisher, R. S. (2001) · Gastroenterology · doi:10.1053/gast.2001.21177 · Cited by 114
Alterations of food antigen‐specific serum immunoglobulins G and E antibodies in patients with irritable bowel syndrome and functional dyspepsia
Zuo, X. L., Li, Y. Q., Li, W. J., Guo, Y. T., Lu, X. F., Li, J. M., & Desmond, P. V. (2007) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2007.02727.x · Cited by 113
Long-term sensitization of primary afferents in adult rats exposed to neonatal colon pain
Lin, C., & Al–Chaer, E. D. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02358-8 · Cited by 113
Review of Fecal Biomarkers in Inflammatory Bowel Disease
Sutherland, A. D., Gearry, R. B., & Frizelle, F. (2008) · Diseases of the Colon & Rectum · doi:10.1007/s10350-008-9310-8 · Cited by 113
Placebo-controlled trial of lubiprostone for constipation associated with Parkinson disease
Ondo, W. G., Kenney, C., Sullivan, K., Davidson, A., Hunter, C., Jahan, I., McCombs, A., Miller, A., & Zesiewicz, T. A. (2012) · Neurology · doi:10.1212/wnl.0b013e3182574f28 · Cited by 112
Treatment of Chronic Constipation: Current Pharmacologic Approaches and Future Directions
Tack, J. F., & Müller-Lissner, S. A. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.12.006 · Cited by 113
Self-citation
Dose finding study of mosapride in functional dyspepsia: a placebo‐controlled, randomized study
Hallerbäck, B., Bommelaer, G., Bredberg, E., Campbell, M., Hellblom, M., Lauritsen, K., WIENBECK, M., & Holmgren, L. ‐. (2002) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2002.01236.x · Cited by 112
Anorectal Dysfunction in Constipated Women With Anorexia Nervosa
Chiarioni, G., Bassotti, G., Monsignori, A., Menegotti, M., Salandini, L., Matteo, G. D., Vantini, I., & Whitehead, W. E. (2000) · Mayo Clinic Proceedings · doi:10.4065/75.10.1015 · Cited by 112
The Treatment of Chronic Constipation in Elderly People
Bosshard, W., Dreher, R., Schnegg, J.-F. O., & Büla, C. (2004) · Drugs & Aging · doi:10.2165/00002512-200421140-00002 · Cited by 114
Treatment With Hypnotherapy Reduces the Sensory and Motor Component of the Gastrocolonic Response in Irritable Bowel Syndrome
Simrén, M., Ringström, G., Björnsson, E. S., & Abrahamsson, H. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000116964.76529.6e · Cited by 111
Small intestinal bacterial overgrowth in irritable bowel syndrome: association with colon motility, bowel symptoms, and psychological distress
Grover, M., Kanazawa, M., Palsson, O. S., Chitkara, D. K., Gangarosa, L. M., Drossman, D. A., & Whitehead, W. E. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01142.x · Cited by 111
Self-citation
Defining the predictors of the placebo response in irritable bowel syndrome
Pitz, M., Cheang, M., & Bernstein, C. N. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00626-3 · Cited by 111
New perspectives in the diagnosis and management of enteric neuropathies
Knowles, C. H., Lindberg, G., Panza, E., & GIORGIO, R. D. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.18 · Cited by 113
Neuropathophysiology of functional gastrointestinal disorders
Wood, J. D. (2007) · World Journal of Gastroenterology · doi:10.3748/wjg.v13.i9.1313 · Cited by 111
Impact of irritable bowel syndrome (IBS) on health-related quality of life (HRQOL)
Amouretti, M., Le Pen, C., Gaudin, A.-F., Bommelaer, G., Frexinos, J., Ruszniewski, P., Poynard, T., Maurel, F., Priol, G., & El Hasnaoui, A. (2006) · Gastroentérologie Clinique et Biologique · doi:10.1016/s0399-8320(06)73160-8 · Cited by 110
A new questionnaire for constipation and faecal incontinence
Bharucha, A. E., Locke, G. R., Seide, B. M., & Zinsmeister, A. R. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.02028.x · Cited by 110
Systematic review: the influence of geography and ethnicity in irritable bowel syndrome
Kang, J. Y. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02396.x · Cited by 110
Impaired Viscerosomatic Reflexes and Abdominal-Wall Dystony Associated With Bloating
Tremolaterra, F., Villòria, A., Azpiroz, F., Serra, J., Aguadé‐Bruix, S., & Malagelada, J. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.12.036 · Cited by 110
A dose‐ranging, placebo‐controlled, randomized trial of alosetron in patients with functional dyspepsia
Talley, N. J., ZANTEN, S. V. V., Saez, L. R., Dukes, G. E., Perschy, T. L., Heath, M., Kleoudis, C. S., & Mangel, A. W. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.00941.x · Cited by 110
A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome
Ishaque, S. M., Khosruzzaman, S. M., Ahmed, D. S., & Sah, M. P. (2018) · BMC Gastroenterology · doi:10.1186/s12876-018-0788-9 · Cited by 109
Some Patients With Irritable Bowel Syndrome May Have Exocrine Pancreatic Insufficiency
Leeds, J. S., Hopper, A. D., Sidhu, R., Simmonette, A., Azadbakht, N., Hoggard, N., Morley, S., & Sanders, D. S. (2010) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2009.09.032 · Cited by 109
Single‐blind follow‐up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome
TSUCHIYA, J., BARRETO, R., OKURA, R., KAWAKITA, S., FESCE, E., & MAROTTA, F. (2004) · Chinese Journal of Digestive Diseases · doi:10.1111/j.1443-9573.2004.00176.x · Cited by 108
Fatigue in patients with primary sclerosing cholangitis
Bjornsson, E. S., Simrén, M., Olsson, R., & Chapman, R. W. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520410003434 · Cited by 108
Gut focused behavioural treatment (biofeedback) for constipation and faecal incontinence in multiple sclerosis
Wiesel, P. H. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.69.2.240 · Cited by 108
Effects of a κ-opioid agonist, asimadoline, on satiation and GI motor and sensory functions in humans
Delgado-Aros, S., Chial, H. J., Camilleri, M., Szarka, L. A., Weber, F. T., Jacob, J., Ferber, I. J., McKinzie, S., Burton, D. D., & Zinsmeister, A. R. (2003) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00360.2002 · Cited by 108
Constipation in older patients: effects on quality of life
Norton, C. S. (2006) · British Journal of Nursing · doi:10.12968/bjon.2006.15.4.20542 · Cited by 108
Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome
Distrutti, E., Cipriani, S., Mencarelli, A., Renga, B., & Fiorucci, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063893 · Cited by 107
Treatment of Diarrhea-Predominant Irritable Bowel Syndrome with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Trial
Leung, W. K., Wu, J. C., Liang, S., Chan, L., Chan, F. K. L., Xie, H., Fung, S. S. L., Hui, A. J., Wong, V. W., Che, C., et al. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00576.x · Cited by 107
Clinical Patterns Over Time in Irritable Bowel Syndrome: Symptom Instability and Severity Variability
Mearin, F., Baró, E., Roset, M., Badia, X. C., Zárate-López, N., & Pérez, I. (2004) · The American Journal of Gastroenterology · doi:10.1046/j.1572-0241.2003.04023.x · Cited by 107
Peppermint oil in irritable bowel syndrome
Grigoleit, H.-G., & Grigoleit, P. (2005) · Phytomedicine · doi:10.1016/j.phymed.2004.10.005 · Cited by 107
Epidemiology and Management of Diverticular Disease of the Colon
Kang, J.-Y., Melville, D. M., & Maxwell, J. D. (2004) · Drugs & Aging · doi:10.2165/00002512-200421040-00001 · Cited by 107
Nutrition and lifestyle in relation to bowel movement frequency: a cross-sectional study of 20 630 men and women in EPIC–Oxford
Sanjoaquin, M. A., Appleby, P. N., Spencer, E. A., & Key, T. J. (2004) · Public Health Nutrition · doi:10.1079/phn2003522 · Cited by 108
Quality of Life in Irritable Bowel Syndrome
Lea, R., & Whorwell, P. J. (2001) · PharmacoEconomics · doi:10.2165/00019053-200119060-00003 · Cited by 106
Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats
Schwetz, I., McRoberts, J. A., Coutinho, S. V., Bradesi, S., Gale, G. D., Fanselow, M. S., Million, M., Ohning, G., Taché, Y., Plotsky, P. M., et al. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00498.2004 · Cited by 109
DYSSYNERGIC DEFECATION
Rao, S. S. C. (2001) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(05)70169-2 · Cited by 106
Non-celiac Gluten Sensitivity
Lundin, K. E. A., & Alaedini, A. (2012) · Gastrointestinal Endoscopy Clinics of North America · doi:10.1016/j.giec.2012.07.006 · Cited by 105
Biofeedback for pelvic floor dysfunction in constipation
Bassotti, G., Chistolini, F., Sietchiping-Nzepa, F., Roberto, G. D., Morelli, A., & Chiarioni, G. (2004) · BMJ · doi:10.1136/bmj.328.7436.393 · Cited by 105
Mechanisms of intestinal gas retention in humans: impaired propulsion versus obstructed evacuation
Serra, J., Azpiroz, F., & Malagelada, J.-R. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.1.g138 · Cited by 104
Bloating and Distension in Irritable Bowel Syndrome: The Role of Gastrointestinal Transit
Agrawal, A., Houghton, L. A., Reilly, B., Morris, J., & Whorwell, P. J. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.251 · Cited by 104
Irritable Bowel Syndrome in Primary Care: The Patients’ and Doctors’ Views on Symptoms, Etiology and Management
Bijkerk, C. J., de Wit, N. J., Stalman, W. A. B., Knottnerus, J. A., Hoes, A. W., & Muris, J. W. M. (2003) · Canadian Journal of Gastroenterology · doi:10.1155/2003/532138 · Cited by 104
Bowel Dysfunction in Patients with Motor Complete Spinal Cord Injury: Clinical, Neurological, and Pathophysiological Associations
Vallès, M., Vidal, J., Clavé, P., & Mearin, F. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00729.x · Cited by 104
Irritable Bowel Syndrome: Toward an Understanding of Severity
Lembo, A. J., Ameen, V. Z., & Drossman, D. A. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00157-6 · Cited by 103
Self-citation

Authors: Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A.
Affiliations: Kaiser Permanente (US)
Corresponding author: Thompson, W G
ORCID: Thompson, W G
Longstreth, G F
Drossman, D A
Venue: Gut
Publisher: BMJ
Published: 1999-09-01
Volume: 45
Issue: suppl 2
Pages: II43-II47
ISSN: 0017-5749 (ISSN-L)
1468-3288
DOI: 10.1136/gut.45.2008.ii43
PMC: PMC1766683
OpenAlex: W2166386674
Semantic Scholar: 9e1a4a0b207039b5d64277278fb3532bc6348472
Cited by: 2,440
References: 36
Citations by year: 2026: 11 · 2025: 20 · 2024: 18 · 2023: 38 · 2022: 28 · 2021: 47 · 2020: 36 · 2019: 30 · 2018: 47 · 2017: 43 · 2016: 64 · 2015: 77 · 2014: 81 · 2013: 92 · 2012: 123
FWCI: 64.06
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Gut (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
HighWire Press Open Archive (submittedVersion)
UNC Libraries
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
Keywords: functional bowel disorders, functional abdominal pain, irritable bowel syndrome, functional constipation, functional diarrhea, diagnostic criteria revision, treatment guidelines, pain behavior, dietary change, psychotherapy, pharmacotherapy
MeSH terms: Colonic Diseases, Functional, Constipation, Diarrhea, Gastrointestinal Diseases, Humans, Abdominal Pain

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Functional bowel disorders and functional abdominal pain

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks