The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
Natural history of elderly-onset inflammatory bowel disease: a population-based cohort study
Abstract
Data on the natural history of elderly-onset inflammatory bowel disease (IBD) are scarce. Methods: In a French population-based cohort we identified 841 IBD patients >60 years of age at diagnosis from 1988 to 2006, including 367 Crohn's disease (CD) and 472 ulcerative colitis (UC). Results: Median age at diagnosis was similar for CD (70 years (IQR: 65–76)) and UC (69 years (64–74)). Median follow-up was 6 years (2–11) for both diseases. At diagnosis, in CD, pure colonic disease (65%) and inflammatory behaviour (78%) were the most frequent phenotype. At maximal follow-up digestive extension and complicated behaviour occurred in 8% and 9%, respectively. In UC, 29% of patients had proctitis, 45% left-sided and 26% extensive colitis without extension during follow-up in 84%. In CD cumulative probabilities of receiving corticosteroids (CSs), immunosuppressants (ISs) and anti tumor necrosis factor therapy were respectively 47%, 27% and 9% at 10 years. In UC cumulative probabilities of receiving CS and IS were 40% and 15%, respectively at 10 years. Cumulative probabilities of surgery at 1 year and 10 years were 18% and 32%, respectively in CD and 4% and 8%, respectively in UC. In CD complicated behaviour at diagnosis (HR: 2.6; 95% CI 1.5 to 4.6) was associated with an increased risk for surgery while CS was associated with a decreased risk (HR: 0.5; 0.3 to 0.8). In UC CS was associated with an increased risk (HR: 2.2; 1.1 to 4.6) for colectomy. Conclusions: Clinical course is mild in elderly-onset IBD patients. This information would need to be taken into account by physicians when therapeutic strategies are established.
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Satsangi, J., Silverberg, M. S., Vermeire, S., & Colombel, J.-F. (2006) · Gut · doi:10.1136/gut.2005.082909 · Cited by 3,176
Self-citationEpidemiology and Natural History of Inflammatory Bowel Diseases
Cosnes, J., Gower–Rousseau, C., Seksik, P., & Cortot, A. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.01.055 · Cited by 2,211
Self-citationLong-Term Evolution of Disease Behavior of Crohn's Disease
Cosnes, J., Cattan, S., Blain, A., Beaugerie, L., Carbonnel, F., Parc, R., & Gendre, J.-P. (2002) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200207000-00002 · Cited by 1,346
Faubion, W. A., Loftus, E. V., Harmsen, W. S., Zinsmeister, A. R., & Sandborn, W. J. (2001) · Gastroenterology · doi:10.1053/gast.2001.26279 · Cited by 1,144
Beaugerie, L., Brousse, N., Bouvier, A. M., Colombel, J. F., Lémann, M., Cosnes, J., Hébuterne, X., Cortot, A., Bouhnik, Y., Gendre, J. P., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61302-7 · Cited by 1,115
Self-citationThe Natural History of Adult Crohn's Disease in Population-Based Cohorts
Peyrin-Biroulet, L., Loftus, E. V., Colombel, J.-F., & Sandborn, W. J. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2009.579 · Cited by 1,047
Self-citationShivananda, S., Lennard-Jones, J., Logan, R., Fear, N., Price, A., Carpenter, L., & van Blankenstein, M. (1996) · Gut · doi:10.1136/gut.39.5.690 · Cited by 1,028
Louis, E., Collard, A., Oger, A. F., Degroote, E., El Yafi, F. A. N., & Belaiche, J. (2001) · Gut · doi:10.1136/gut.49.6.777 · Cited by 1,005
Thia, K. T., Sandborn, W. J., Harmsen, W. S., Zinsmeister, A. R., & Loftus, E. V. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.06.070 · Cited by 792
Solberg, I. C., Lygren, I., Jahnsen, J., Aadland, E., Høie, O., Cvancarova, M., Bernklev, T., Henriksen, M., Sauar, J., Vatn, M. H., et al. (2009) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520802600961 · Cited by 731
Cited by
Changing epidemiological trends of inflammatory bowel disease in Asia
Ng, W. K., Wong, S. H., & Ng, S. C. (2016) · Intestinal Research · doi:10.5217/ir.2016.14.2.111 · Cited by 299
Systematic review with meta-analysis: inflammatory bowel disease in the elderly
Gisbert, J. P., & Chaparro, M. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12616 · Cited by 158
The Impact of Inflammatory Bowel Disease in Canada 2018: IBD in Seniors
Nguyen, G. C., Targownik, L. E., Singh, H., Benchimol, E. I., Bitton, A., Murthy, S. K., Bernstein, C. N., Lee, K., Cooke-Lauder, J., & Kaplan, G. G. (2019) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwy051 · Cited by 44
Metadata
- Authors
- Charpentier, C., Salleron, J., Savoye, G., Fumery, M., Merle, V., Laberenne, J.-E., Vasseur, F., Dupas, J.-L., Cortot, A., Dauchet, L., Peyrin-Biroulet, L., Lerebours, E., Colombel, J.-F., & Gower-Rousseau, C.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2013-02-13
- Volume
- 63
- Issue
- 3
- Pages
- 423-432
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2127482800
- Cited by
- 355
- References
- 58
- FWCI
- 15.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Charpentier, C., Salleron, J., Savoye, G., Fumery, M., Merle, V., Laberenne, J.-E., Vasseur, F., Dupas, J.-L., Cortot, A., Dauchet, L., Peyrin-Biroulet, L., Lerebours, E., Colombel, J.-F., & Gower-Rousseau, C. (2014). Natural history of elderly-onset inflammatory bowel disease: a population-based cohort study. Gut. https://doi.org/10.1136/gutjnl-2012-303864
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