Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

Dao, Maria Carlota; Everard, Amandine; Aron-Wisnewsky, Judith; Sokolovska, Nataliya; Prifti, Edi; Verger, Eric O; Kayser, Brandon D; Levenez, Florence; Chilloux, Julien; Hoyles, Lesley; MICRO-Obes Consortium; Dumas, Marc-Emmanuel; Rizkalla, Salwa W; Doré, Joel; Cani, Patrice D; Clément, Karine

doi:10.1136/gutjnl-2014-308778

Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

Objective Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene richness. Abundance of Akkermansia muciniphila , a mucin-degrading bacterium, has been inversely associated with body fat mass and…