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British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis
Open accessAbstract
These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and gastroenterology groups as well as patient representatives from PSC Support. The guidelines aim to support general physicians, gastroenterologists and surgeons in managing adults with PSC or those presenting with similar cholangiopathies which may mimic PSC, such as IgG4 sclerosing cholangitis. It also acts as a reference for patients with PSC to help them understand their own management. Quality of evidence is presented using the AGREE II format. Guidance is meant to be used as a reference rather than for rigid protocol-based care as we understand that management of patients often requires individual patient-centred considerations.
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“As universally agreed, MRI/MRC is the best non-invasive tool to assess large bile duct changes in PSC.[20][21][22]”
From EASL Clinical Practice Guidelines on sclerosing cholangitis (2022) · cites this paper as [22]
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Metadata
- Authors
- Chapman, M. H., Thorburn, D., Hirschfield, G. M., Webster, G. G. J., Rushbrook, S. M., Alexander, G., Collier, J., Dyson, J. K., Jones, D. E., Patanwala, I., Thain, C., Walmsley, M., & Pereira, S. P.
- Affiliations
- Royal Free London NHS Foundation Trust (GB)
- University Health Network (CA)
- Norfolk and Norwich University Hospital (GB)
- John Radcliffe Hospital (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Newcastle University (GB)
- University of Liverpool (GB)
- PBC Foundation (GB)
- PSC Support (GB)
- University College London (GB)
- Corresponding author
- Pereira, Stephen P
- ORCID
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2019-06-01
- Volume
- 68
- Issue
- 8
- Pages
- 1356-1378
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC6691863
- OpenAlex
- W2947046480
- Cited by
- 284
- References
- 294
- Citations by year
- 2026: 25 · 2025: 40 · 2024: 44 · 2023: 47 · 2022: 46 · 2021: 43 · 2020: 33 · 2019: 5
- FWCI
- 20.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- National Institute for Health and Care Research (NIHR200243)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
- Health Sciences › Medicine › Surgery › Pediatric Hepatobiliary Diseases and Treatments
- Health Sciences › Medicine › Rheumatology › IgG4-Related and Inflammatory Diseases
- Keywords
- primary sclerosing cholangitis, diagnosis, management, cholangiopathy, patient-centered care
- MeSH terms
- Immunoglobulin G4-Related Disease, Biliary Tract Neoplasms, Diagnosis, Differential, Diagnostic Techniques, Digestive System, United Kingdom, Humans, Patient Care Management, Prognosis, Cholangitis, Sclerosing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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