The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Gender differences in clinical presentation and 1-year outcomes in atrial fibrillation
Open accessAbstract
Objectives: Our objective was to examine gender differences in clinical presentation, management and prognosis of atrial fibrillation (AF) in a contemporary cohort. Methods: In 6412 patients, 39.7% women, of the PREvention oF thromboembolic events – European Registry in Atrial Fibrillation, we examined gender differences in symptoms, risk factors, therapies and 1-year incidence of adverse outcomes. Results: Men with AF were on average younger than women (mean±SD: 70.1±10.7 vs 74.1±9.7 years, p<0.0001). Women more frequently had at least one AF-related symptom at least occasionally compared with men (95.4% in women, 89.8% in men, p<0.0001). Prescription of oral anticoagulation was similar, with an increase of non-vitamin K antagonist oral anticoagulants from 5.9% to 12.6% in women and from 6.2% to 12.6% in men, p<0.0001 for both. Men were more frequently treated with electrical cardioversion and ablation (20.6% and 6.3%, respectively) than women (14.9% and 3.3%, respectively), p<0.0001. Women had 65% (OR: 0.35; 95% CI (0.22 to 0.56)) lower age-adjusted and country-adjusted odds of coronary revascularisation, 40% (OR: 0.60; (0.38 to 0.93)) lower odds of acute coronary syndrome and 20% (OR: 0.80; (0.68 to 0.96)) lower odds of heart failure at 1 year. There were no statistically significant gender differences in 1-year stroke/transient ischaemic attack/arterial thromboembolism and major bleeding events. Conclusion: In a ‘real-world’ European AF registry, women were more symptomatic but less likely to receive invasive rhythm control therapy such as electrical cardioversion or ablation. Further study is needed to confirm that these differences do not disadvantage women with AF.
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Cites
ggplot2: Elegant Graphics for Data Analysis
Wickham, H. (2009) · doi:10.1007/978-0-387-98141-3 · Cited by 14,447
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study
Chugh, S. S., Havmoeller, R., Narayanan, K., Singh, D., Rienstra, M., Benjamin, E. J., Gillum, R. F., Kim, Y.-H., McAnulty, J. H., Zheng, Z.-J., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.005119 · Cited by 4,506
Calkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2011.12.016 · Cited by 1,456
Self-citationEmdin, C. A., Wong, C. X., Hsiao, A. J., Altman, D. G., Peters, S. A., Woodward, M., & Odutayo, A. A. (2016) · BMJ · doi:10.1136/bmj.h7013 · Cited by 452
Kirchhof, P., Ammentorp, B., Darius, H., De Caterina, R., Le Heuzey, J.-Y., Schilling, R. J., Schmitt, J., & Zamorano, J. L. (2014) · EP Europace · doi:10.1093/europace/eut263 · Cited by 404
New-Onset Atrial Fibrillation: Sex Differences in Presentation, Treatment, and Outcome
Humphries, K. H., Kerr, C. R., Connolly, S. J., Klein, G., Boone, J. A., Green, M., Sheldon, R., Talajic, M., Dorian, P., & Newman, D. (2001) · Circulation · doi:10.1161/01.cir.103.19.2365 · Cited by 378
Friberg, L., Skeppholm, M., & Terént, A. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.10.052 · Cited by 207
Gender-related differences in catheter ablation of atrial fibrillation
Forleo, G. B., Tondo, C., De Luca, L., Russo, A. D., Casella, M., De Sanctis, V., Clementi, F., Fagundes, R. L., Leo, R., Romeo, F., et al. (2007) · EP Europace · doi:10.1093/europace/eum144 · Cited by 189
Soliman, E. Z., Lopez, F., O’Neal, W. T., Chen, L. Y., Bengtson, L., Zhang, Z.-M., Loehr, L., Cushman, M., & Alonso, A. (2015) · Circulation · doi:10.1161/circulationaha.114.014145 · Cited by 174
Cited by
Dai, H., Zhang, Q., Much, A. A., Maor, E., Segev, A., Beinart, R., Adawi, S., Lu, Y., Bragazzi, N. L., & Wu, J. (2021) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcaa061 · Cited by 322
Graphics and statistics for cardiology: designing effective tables for presentation and publication
Boers, M. (2018) · Heart · doi:10.1136/heartjnl-2017-311581 · Cited by 56
Racial, ethnic, and sex disparities in atrial fibrillation management: rate and rhythm control
Gomez, S. E., Fazal, M., Nunes, J. C., Shah, S., Perino, A. C., Narayan, S. M., Tamirisa, K. P., Han, J. K., Rodriguez, F., & Baykaner, T. (2022) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-022-01383-x · Cited by 24
Metadata
- Authors
- Schnabel, R. B., Pecen, L., Ojeda, F. M., Lucerna, M., Rzayeva, N., Blankenberg, S., Darius, H., Kotecha, D., Caterina, R. D., & Kirchhof, P.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2017-02-22
- Volume
- 103
- Issue
- 13
- Pages
- 1024-1030
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- OpenAlex
- W2591054392
- Cited by
- 176
- References
- 9
- FWCI
- 10.15
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Schnabel, R. B., Pecen, L., Ojeda, F. M., Lucerna, M., Rzayeva, N., Blankenberg, S., Darius, H., Kotecha, D., Caterina, R. D., & Kirchhof, P. (2017). Gender differences in clinical presentation and 1-year outcomes in atrial fibrillation. Heart. https://doi.org/10.1136/heartjnl-2016-310406
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