The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Prognostic significance of frequent premature ventricular contractions originating from the ventricular outflow tract in patients with normal left ventricular function
Open accessAbstract
Background: Recently, it has been reported that frequent premature ventricular contractions (PVCs) may be associated with causing heart failure in patients with left ventricular (LV) dysfunction. However, the prognostic significance of frequent PVCs in asymptomatic patients with a normal LV function is unclear. Methods: Two hundred and thirty-nine consecutive patients presenting with frequent PVCs (>1000 beats/day) originating from the right or left ventricular outflow tract without any detectable heart disease were enrolled in the study. Structural heart disease was ruled out by echocardiography and cardiac magnetic resonance imaging, and Holter-ECG monitoring was repeated two or three times to evaluate the PVC prevalence at the initial evaluation. All patients were followed up for at least 4 years, and further observation was continued if possible. Results: During an observation period of 5.6 (1.7) years, no patients exhibited any serious cardiac events. Although there was no significant change in the mean LV ejection fraction (LVEF) and mean LV diastolic dimension (LVDd), there was a significant negative correlation between the PVC prevalence and ΔLVEF (p<0.001) and positive correlation between the PVC prevalence and ΔLVDd (p<0.001). When the development of LV dysfunction was defined as ΔLVEF>−6%, 13 patients exhibited LV dysfunction. For the prediction of the development of LV dysfunction, PVC prevalence and LVEF at the initial evaluation were independent predicting factors (p<0.01). Conclusion: Although the prognosis in patients with frequent PVCs was considered relatively benign, attention should be paid to the progression of the LV dysfunction during a long-term observation, especially in patients with a high PVC prevalence.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bogun, F., Crawford, T., Reich, S., Koelling, T. M., Armstrong, W., Good, E., Jongnarangsin, K., Marine, J. E., Chugh, A., Pelosi, F., et al. (2007) · Heart Rhythm · doi:10.1016/j.hrthm.2007.03.003 · Cited by 438
Yarlagadda, R. K., Iwai, S., Stein, K. M., Markowitz, S. M., Shah, B. K., Cheung, J. W., Tan, V., Lerman, B. B., & Mittal, S. (2005) · Circulation · doi:10.1161/circulationaha.105.546432 · Cited by 395
Takemoto, M., Yoshimura, H., Ohba, Y., Matsumoto, Y., Yamamoto, U., Mohri, M., Yamamoto, H., & Origuchi, H. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.073 · Cited by 348
CHUGH, S. S., SHEN, W., LURIA, D. M., & SMITH, H. C. (2000) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2000.tb01802.x · Cited by 214
Lemery, R., Brugada, P., Bella, P. D., Dugernier, T., van den Dool, A., & Wellens, H. J. (1989) · Circulation · doi:10.1161/01.cir.79.5.990 · Cited by 213
Long-term follow-up of right ventricular monomorphic extrasystoles
Gaita, F., Giustetto, C., Di Donna, P., Richiardi, E., Libero, L., Brusin, M. C. R., Molinari, G., & Trevi, G. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01403-6 · Cited by 184
Duffee, D. F., Shen, W.-K., & Smith, H. C. (1998) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)63724-5 · Cited by 179
O'Donnell, D. (2003) · European Heart Journal · doi:10.1016/s0195-668x(02)00654-1 · Cited by 171
Radiofrequency catheter ablation for management of symptomatic ventricular ectopic activity
ZHU, D. W. X., Maloney, J. D., Simmons, T. W., Nitta, J., Fitzgerald, D. M., Trohman, R. G., Khoury, D. S., Saliba, W., Belco, K. M., Rizo-Patrón, C., et al. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00287-7 · Cited by 143
Sekiguchi, Y., Aonuma, K., Yamauchi, Y., et al. (2005) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2005.40786.x · Cited by 90
Cited by
Relationship between burden of premature ventricular complexes and left ventricular function
Baman, T. S., Lange, D. C., Ilg, K. J., Gupta, S. K., Liu, T.-Y., Alguire, C., Armstrong, W., Good, E., Chugh, A., Jongnarangsin, K., et al. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.03.036 · Cited by 676
EHRA/HRS/APHRS expert consensus on ventricular arrhythmias
Pedersen, C. T., Kay, G. N., Kalman, J., Borggrefe, M., Della-Bella, P., Dickfeld, T., Dorian, P., Huikuri, H., Kim, Y.-H., Knight, B., et al. (2014) · Heart Rhythm · doi:10.1016/j.hrthm.2014.07.024 · Cited by 288
Nielsen, J. C., Lin, Y.-J., de Oliveira Figueiredo, M. J., Sepehri Shamloo, A., Alfie, A., Boveda, S., Dagres, N., Di Toro, D., Eckhardt, L. L., Ellenbogen, K., et al. (2020) · EP Europace · doi:10.1093/europace/euaa065 · Cited by 98
What about Tachycardia-induced cardiomyopathy?
Ellis, E. R., Josephson, M. E., Clinical Fellow, H. M. S., & Herman C. Dana Professor of Medicine, H. M. S. (2013) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2013.2.2.82 · Cited by 55
Evaluation and management of premature ventricular complexes
Cantillon, D. J. (2013) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.80a.12168 · Cited by 43
Metadata
- Authors
- Niwano, S., Wakisaka, Y., Niwano, H., Fukaya, H., Kurokawa, S., Kiryu, M., Hatakeyama, Y., & Izumi, T.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2009-05-07
- Volume
- 95
- Issue
- 15
- Pages
- 1230-1237
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- OpenAlex
- W2120059575
- Cited by
- 299
- References
- 17
- FWCI
- 8.50
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Prognostic significance of frequent premature ventricular contractions originating from the ventricular outflow tract in patients with normal left ventricular function. https://app.cochat.ai/papers/10.1136/hrt.2008.159558
- The paper
- Niwano, S., Wakisaka, Y., Niwano, H., Fukaya, H., Kurokawa, S., Kiryu, M., Hatakeyama, Y., & Izumi, T. (2009). Prognostic significance of frequent premature ventricular contractions originating from the ventricular outflow tract in patients with normal left ventricular function. Heart. https://doi.org/10.1136/hrt.2008.159558
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
