Cited by 55Cardiac Arrhythmias and TreatmentsCardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

What about Tachycardia-induced cardiomyopathy?

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Ellis, Ethan R, Josephson, Mark E, Clinical Fellow, Harvard Medical School, Beth Israel Deaconess Medical Center, Herman C. Dana Professor of Medicine, Harvard Medical School, Chief of the Cardiovascular Division, Beth Israel Deaconess Medical Center and Director, Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, US. E: mjoseph2@bidmc.harvard.edu·2013·Arrhythmia & Electrophysiology Review

Abstract

Long-standing tachycardia is a well-recognised cause of heart failure and left ventricular dysfunction, and has led to the nomenclature, tachycardia-induced cardiomyopathy (TIC). TIC is generally a reversible cardiomyopathy if the causative tachycardia can be treated effectively, either with medications, surgery or catheter ablation. The diagnosis is usually made after demonstrating recovery of left ventricular function with normalisation of heart rate in the absence of other identifiable aetiologies. One hundred years after the first reported case of TIC, our understanding of the pathophysiology of TIC in humans remains limited despite extensive work in animal models of TIC. In this review we will discuss the proposed mechanisms of TIC, the causative tachyarrhythmias and their treatment, outcomes for patients diagnosed with TIC, and future directions for research and clinical care.

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  1. Whipple G, Sheffield L, Woodman E, et al. Reversible congestive heart failure due to chronic rapid stimulation of the normal heart. Proc N Engl Cardiovasc Soc 1962; 20:39-40.

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Authors
Ellis, E. R., Josephson, M. E., Clinical Fellow, H. M. S., & Herman C. Dana Professor of Medicine, H. M. S.
Affiliations
Beth Israel Deaconess Medical Center (US)
Venue
Arrhythmia & Electrophysiology Review
Published
2013
Volume
2
Issue
2
Pages
82
ISSN
  • 2050-3369 (ISSN-L)
  • 2050-3377
OpenAlex
W2330198299
Cited by
55
References
139
Citations by year
2026: 5 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 3 · 2021: 7 · 2020: 8 · 2019: 8 · 2018: 4 · 2017: 6 · 2016: 1
FWCI
0.23
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Arrhythmia & Electrophysiology Review (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
tachycardia-induced cardiomyopathy, heart failure, left ventricular dysfunction, tachyarrhythmias, catheter ablation, left ventricular function recovery, pathophysiology, animal models, treatment outcomes

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