Governance for clinical decision support: case studies and recommended practices from leading institutions
Open accessAbstract
OBJECTIVE: Clinical decision support (CDS) is a powerful tool for improving healthcare quality and ensuring patient safety; however, effective implementation of CDS requires effective clinical and technical governance structures. The authors sought to determine the range and variety of these governance structures and identify a set of recommended practices through observational study. DESIGN: Three site visits were conducted at institutions across the USA to learn about CDS capabilities and processes from clinical, technical, and organizational perspectives. Based on the results of these visits, written questionnaires were sent to the three institutions visited and two additional sites. Together, these five organizations encompass a variety of academic and community hospitals as well as small and large ambulatory practices. These organizations use both commercially available and internally developed clinical information systems. MEASUREMENTS: Characteristics of clinical information systems and CDS systems used at each site as well as governance structures and content management approaches were identified through extensive field interviews and follow-up surveys. RESULTS: Six recommended practices were identified in the area of governance, and four were identified in the area of content management. Key similarities and differences between the organizations studied were also highlighted. CONCLUSION: Each of the five sites studied contributed to the recommended practices presented in this paper for CDS governance. Since these strategies appear to be useful at a diverse range of institutions, they should be considered by any future implementers of decision support.
AI snapshot
Written from the paper’s full text.
TL;DR
This paper reports an observational, qualitative study of clinical decision support (CDS) governance at five diverse US healthcare organizations and distills recommended practices for governance and content management. It identifies six governance practices and four content-management practices, while cautioning that the findings come from a small, purposively selected, nonrepresentative sample.
Key findings
- Five organizations were studied: Partners HealthCare System, Mid-Valley Independent Physicians Association, Vanderbilt Medical Group, Veterans Health Administration, and University of Texas Physicians’ Practice Plan.
- All sites had at least one example of each of the six Osheroff CDS types, but depth varied widely: condition-specific order sets ranged from less than 50 to more than 800, and unique clinical alerts ranged from less than 50 to more than 7000.
- The authors identified six recommended practices for CDS governance and four recommended practices for content management.
- Governance differed substantially between sites using vendor-based clinical information systems and those with internally developed systems; vendor-based sites had fewer, more centralized committees and limited customization, while internally developed sites had larger specialized staff, more committees, and more local customization.
Methods
- Observational qualitative study using the Rapid Assessment Process, with three site visits and five comprehensive surveys at purposively selected exemplary institutions with a history of successful CDS research and utilization.
- Site visits involved four to seven researchers (physicians, nurses, pharmacists, informaticians), interviews with CDS developers and information system leaders, observations of clinical end users, tape-recorded interviews, and detailed field notes.
- Analysis used grounded theory, NVivo 8 qualitative data-analysis software, card-sorting to distill themes, and follow-up written questionnaires plus a CDS content inventory based on Osheroff et al.’s six CDS categories.
Limitations
- The paper states that data came from five exemplary sites that were “purposefully nonrepresentative of typical practice,” limiting generalizability.
- The paper states that only US institutions were studied, further limiting generalizability, and that recommended practices were based on consensus and expert opinion, so some effective practices may have been missed.
- The paper states that it could not characterize the cost of CDS governance or study financial implications of different governance approaches; it also notes no interventional or wide-scale observational evidence exists for the effect of CDS governance practices.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
0 of 15 cited sources checked · 0 supported · 0 flagged
- Findingnone given
All of the sites provided some capability for user feedback, ranging from feedback buttons embedded in the EHR application to email, helpdesk query tracking, and clinical representation on committees.
“All of the sites provided some capability for user feedback, ranging from feedback buttons embedded in the EHR application to email, helpdesk query tracking, and clinical representation on committees.”
Quote in the paperNot a substantial claim - Findingown data
The sites varied dramatically in the depth of decision support they had.
“Despite having similar breadth of CDS, the sites varied dramatically in the depth of decision support they had.”
Quote in the paperSubstantial claim - Findingnone given
Vendor-based clinical information systems have regular reports from vendors.
“Regular reports from vendors”
Quote in the paperNot a substantial claim - Findingown data
Several of the sites reported having special-purpose software tools for managing content throughout the knowledge management life cycle.
“Several of the sites reported having special-purpose software tools for managing content throughout this knowledge management life cycle.”
Quote in the paperNot a substantial claim - Findingown data
Internally developed clinical information systems have more, specialized committees.
“More, specialized committees”
Quote in the paperSubstantial claim
- Findingnone given
Some sites, particularly the VA, reported a strong focus on associated quality measures.
“In addition to direct CDS-related evaluation, some sites (particularly the VA) reported a strong focus on associated quality measures.”
Quote in the paperNot a substantial claim - Findingown data
Sites varied in the degree to which they allowed tailoring of CDS content in individual practices or hospital services.
“Sites also varied in the degree to which they allowed tailoring of CDS content in individual practices or hospital services.”
Quote in the paperNot a substantial claim - Findingnone given
Internally developed clinical information systems require large staff with specialized clinical knowledge.
“Require large staff with specialized clinical knowledge”
Quote in the paperSubstantial claim - Findingown data
Vendor-based clinical information systems manage content centrally by the vendor.
“Content managed centrally by vendor”
Quote in the paperSubstantial claim - Findingown data
The form and pattern of governance models differed greatly across the five sites.
“All five sites in our analysis had at least some degree of decisionsupport governance, although the form and pattern of governance models differed greatly.”
Quote in the paperNot a substantial claim - Findingown data
Internally developed clinical information systems manage content through organization-wide committees with distinct specializations.
“Content managed through organization-wide committees with”
- Also stated in: § CONCLUSIONS · plain
“distinct specializations”
Quote in the paperSubstantial claim - Also stated in: § CONCLUSIONS · plain
- Findingown data
Internally developed clinical information systems have regular usage monitoring and research evaluation.
“Regular usage monitoring and research evaluation”
Quote in the paperSubstantial claim - Findingown data
The number of unique clinical alerts ranged from less than 50 to more than 7000 across the sites.
“For example, the number of different condition-specific order sets ranged from less than 50 to more than 800, and the number of unique clinical alerts ranged from less than 50 to more than 7000.”
Quote in the paperSubstantial claim - Findingown data
Several of the studied sites had robust measurement programs, where the acceptance and effectiveness of their content are measured after roll-out and on an ongoing basis.
“Several of the studied sites had robust measurement programs, where the acceptance and effectiveness of their content are measured after roll-out and on an ongoing basis.”
Quote in the paperSubstantial claim - Findingown data
Every site had at least some component of a knowledge-management life cycle, even if only the creation part.
“Every site had at least some component of a knowledgemanagement life cycle (even if only the creation part); however, we found seven commonly occurring life-cycle phases, shown in figure 1.”
Quote in the paperNot a substantial claim - Findingown data
Mechanisms of user feedback varied significantly in form and frequency across sites.
“Some form of regular review was common across all sites studied, although mechanisms of user feedback varied significantly in form and frequency.”
Quote in the paperNot a substantial claim - Findingown data
The five sites had learned many overlapping and complementary lessons about governance for CDS.
“The five sites we studied were quite diverse; however, they had also learned many overlapping and complementary lessons about governance for CDS.”
Quote in the paperSubstantial claim - Findingcitation
Over the last 5 years at Partners, with the maturation of the knowledge management group's processes, content is increasingly re-evaluated on a periodic basis, including analysis of usage data such as acceptance and override rates for alerts.
“Over the last 5 years, with the maturation of the knowledge management group's processes, content is increasingly re-evaluated on a periodic basis, which includes analysis of usage data, such as acceptance and override rates for alerts.22 23”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites 22 23
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Findingown data
At Partners, on-demand reviews are prompted by user feedback and external events gleaned from regular scans of health-information sources.
“In addition, on-demand reviews are prompted by user feedback and external events gleaned from regular scans of health-information sources, such as FDA and pharmaceutical company announcements and the medical research literature.”
Quote in the paperNot a substantial claim - Findingnone given
Other sites, including Partners, reported less standardization.
“Other sites, including Partners, reported less standardization.”
Quote in the paperNot a substantial claim - Findingown data
The number of different condition-specific order sets ranged from less than 50 to more than 800 across the sites.
“For example, the number of different condition-specific order sets ranged from less than 50 to more than 800, and the number of unique clinical alerts ranged from less than 50 to more than 7000.”
Quote in the paperSubstantial claim - Findingown data
Balancing research and operational decision-support projects at Partners has been challenging, as research content must be maintained or decommissioned after the research project ends.
“At Partners, a great deal of the CDS content was developed as part of research projects, and balancing research and operational decision-support projects has been challenging, as research content must be maintained (or decommissioned) after the research project ends.”
Quote in the paperNot a substantial claim - Findingown data
Sites needed coordinated ways to manage their decision-support content, particularly as the amount and complexity of the content grew.
“Our research findings clearly revealed that sites needed coordinated ways to manage their decision-support content, particularly as the amount and complexity of the content grew.”
Quote in the paperSubstantial claim - Findingnone given
Internally developed clinical information systems make use of clinical decision-support systems more likely to be mandated.
“Use of clinical decision-support system more likely to be mandated”
Quote in the paperSubstantial claim - Findingown data
Content-management practices differed significantly based on the nature of the organizations.
“The content-management practices of the organizations differed significantly based on the nature of the organizations.”
Quote in the paperNot a substantial claim - Findingown data
Sites which relied more heavily on vendor content were more likely to report periodic updates or refreshes, often tied to vendor release schedules.
“Sites which relied more heavily on vendor content were more likely to report periodic updates or refreshes, often tied to vendor release schedules.”
Quote in the paperNot a substantial claim - Findingown data
Committee structure and overall organization varied across sites.
“Most sites employed the use of committees to govern development, implementation, and maintenance of CDS systems, although committee structure and overall organization varied.”
Quote in the paperNot a substantial claim - Findingnone given
Vendor-based clinical information systems require fewer staff members who support the system and collaborate with the vendor.
“Fewer staff members who support system and collaborate with vendor”
Quote in the paperSubstantial claim - Findingown data
Sites reported developing content based on user requests, regulatory and quality reporting requirements, and other organizational priorities.
“Sites also reported developing content based on user requests, regulatory and quality reporting requirements, and other organizational priorities.”
Quote in the paperNot a substantial claim - Findingnone given
Vendor-based clinical information systems have fewer, possibly one, centralized committee(s).
“Fewer (possibly one) centralized committee(s)”
Quote in the paperSubstantial claim - Findingnone given
Vendor-based clinical information systems make use of clinical decision-support systems more likely to be encouraged.
“Use of clinical decision-support system more likely to be encouraged”
Quote in the paperSubstantial claim - Findingown data
Some form of regular review was common across all sites studied.
“Some form of regular review was common across all sites studied, although mechanisms of user feedback varied significantly in form and frequency.”
Quote in the paperNot a substantial claim - Findingnone given
Vendor-based clinical information systems have limited or no customization permitted.
“Limited or not permitted”
Quote in the paperSubstantial claim - Findingown data
All five sites had at least some degree of decision-support governance.
“All five sites in our analysis had at least some degree of decisionsupport governance, although the form and pattern of governance models differed greatly.”
Quote in the paperNot a substantial claim - Findingown data
Both internally developed and vendor-based clinical information systems employ a variety of tools for user feedback.
“Variety of tools employed”
Quote in the paperSubstantial claim - Findingown data
Each site had at least one example of each of the six decision-support types in the Osheroff taxonomy.
“In addition to the broad demographic characteristics in table 1, we found that each site had at least one example of each of the six decision-support types in the Osheroff taxonomy, suggesting that each site had sufficient breadth of content to necessitate some level of decision-support governance.”
Quote in the paperSubstantial claim - Findingown data
Academic medical centers reported that much of their content was, at least initially, developed by researchers as part of research projects.
“Academic medical centers reported that much of their content was, at least initially, developed by researchers as a part of research projects.”
Quote in the paperNot a substantial claim - Findingreasoning
Vanderbilt has several mechanisms to assess ongoing proper functioning of clinical content.
“Vanderbilt has several mechanisms to assess ongoing proper functioning of clinical content.”
Quote in the paperNot a substantial claim - Findingnone given
Vanderbilt collects surveillance data on order set usage, responses to decision-support pop-up alerts, and other CDS items to adjust the support to the desired outcome.
“Surveillance data are collected on order set usage, responses to decision-support pop-up alerts, and other CDS items to adjust the support to the desired outcome.”
Quote in the paperNot a substantial claim - Findingown data
Most sites employed committees to govern development, implementation, and maintenance of CDS systems.
“Most sites employed the use of committees to govern development, implementation, and maintenance of CDS systems, although committee structure and overall organization varied.”
Quote in the paperNot a substantial claim - Findingcitation
The most robust review mechanisms at Partners are in place for formulary drug information, drug-drug interaction rules, age- and renal-based drug dosing guidance rules, and health maintenance reminders.
“The most robust review mechanisms are in place for formulary drug information (dose and frequency lists), drugedrug interaction rules, 24 age-and renal-based drug dosing guidance rules, 25 and health maintenance reminders.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [24]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [25]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Findingown data
Some sites reported monitoring usage of content in order to prioritize the most highly used content.
“Some sites also reported monitoring usage of content in order to prioritize the most highly used content.”
Quote in the paperNot a substantial claim - Findingown data
Feedback mechanisms ranged from passive receipt of reports to active feedback tools embedded in the EHR and periodic site visits and assessments.
“These feedback mechanisms ranged from passive receipt of reports to active feedback tools embedded in the EHR and periodic site visits and assessments.”
Quote in the paperNot a substantial claim - Findingown data
Internally developed clinical information systems develop content by committee, employing subject matter experts and knowledge engineers.
“Content developed by committee, employing subject matter experts”
- Also stated in: § CONCLUSIONS · plain
“and knowledge engineers”
Quote in the paperSubstantial claim - Also stated in: § CONCLUSIONS · plain
- Findingown data
Identifying and maintaining this content, particularly after research projects concluded, appeared to be challenging.
“Identifying and maintaining this content, particularly after research projects concluded, appeared to be challenging.”
Quote in the paperNot a substantial claim - Findingown data
CDS-related staff ranged from a small staff responsible for overseeing a vendor system to large academic informatics departments.
“CDS-related staff ranged from a small staff responsible for overseeing a vendor system to large academic informatics departments that included numerous clinicians, informaticians, and software developers.”
Quote in the paperNot a substantial claim - Findingown data
At Partners, a great deal of CDS content was developed as part of research projects.
“At Partners, a great deal of the CDS content was developed as part of research projects, and balancing research and operational decision-support projects has been challenging, as research content must be maintained (or decommissioned) after the research project ends.”
Quote in the paperNot a substantial claim - Findingown data
The authors found seven commonly occurring knowledge-management life-cycle phases.
“Every site had at least some component of a knowledgemanagement life cycle (even if only the creation part); however, we found seven commonly occurring life-cycle phases, shown in figure 1.”
Quote in the paperSubstantial claim - Findingnone given
For these assets, Partners conducts regularly scheduled reviews of content at differing frequencies.
“For these assets, Partners conducts regularly scheduled reviews of content, at differing frequencies.”
Quote in the paperNot a substantial claim - Interpretationown data
Based on the sites studied, the recommended practices seem to be effective general approaches to CDS governance.
“Based on the sites we studied, these practices seem to be effective general approaches to CDS governance.”
Quote in the paperSubstantial claim- Rests on an assumption: The five sites studied are sufficiently diverse and exemplary to yield recommended practices that are useful to other institutions.
- Premisecitation
A critical challenge limiting the wide adoption of CDS is the difficulty of developing and maintaining the required knowledge bases of clinical content.
“A variety of challenges limit the wide adoption of CDS, but a critical one is the difficulty of developing and maintaining the required knowledge bases of clinical content.4 5”
Quote in the paperSubstantial claim0 of 1 sources checked- cites 4 5
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationown data
Each site had sufficient breadth of content to necessitate some level of decision-support governance.
“In addition to the broad demographic characteristics in table 1, we found that each site had at least one example of each of the six decision-support types in the Osheroff taxonomy, suggesting that each site had sufficient breadth of content to necessitate some level of decision-support governance.”
Quote in the paperSubstantial claim - Premisecitation
CDS, when well-designed and effectively implemented, can have positive effects for healthcare quality, patient safety, and the provision of cost-effective care.
“A substantial body of evidence suggests that, when well-designed and effectively implemented, CDS can have positive effects for healthcare quality, patient safety, and the provision of cost-effective care.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites 1 2
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning
Organizations relying on vendor-based CDS require governance structures largely limited to collaboration with vendors and ongoing day-to-day operational management.
“Organizations that rely on vendor-based CDS require governance structures largely limited to collaboration with vendors and ongoing day-to-day operational management.”
Quote in the paperSubstantial claim - Interpretationreasoning
These fundamental differences result in diverging governance practices.
“These fundamental differences result in diverging governance practices, which are summarized in table 3.”
Quote in the paperSubstantial claim - Interpretationcitation
In the absence of effective governance practices, implementation of CDS may fail, despite the purchase or development of a sophisticated system.
“In the absence of effective governance practices, implementation of CDS may fail, despite the purchase or development of a sophisticated system.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [8]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation
Only a small number of sites in the USA have achieved significant success with CDS.
“Although the benefits of decision support are numerous, only a small number of sites in the USA have achieved significant success with it.3”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [3]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning
These differences were largely related to each type of institution's involvement in CDS development, implementation, and management.
“These differences were largely related to each type of institution's involvement in CDS development, implementation and management.”
Quote in the paperSubstantial claim - Interpretationreasoning
Most small sites tend to rely on general-purpose software tools and built-in EHR functions.
“The primary differences are that, in general, most small sites have a limited ability to develop and monitor CDS and, as a result, tend to purchase their decision support from commercial content suppliers, rather than developing the content themselves, and tend to rely on general-purpose software tools and built-in EHR functions.”
Quote in the paperNot a substantial claim - Interpretationnone given
The governance and content-management strategies identified are most applicable for large sites with mature and robust CDS.
“The governance and content-management strategies we identified are most applicable for large sites with mature and robust CDS.”
Quote in the paperSubstantial claim - Premisecitation
Limited research exists about optimal and real-world CDS governance practices.
“Although governance and other organization factors have been noted as an essential aspect of high-quality CDS 9 10 and requisite data warehousing and management, 11 limited research exists about optimal and real-world CDS governance practices.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites 9 10 11
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationown data
The recommended CDS governance strategies appear to be useful at a diverse range of institutions.
“Since these strategies appear to be useful at a diverse range of institutions, they should be considered by any future implementers of decision support.”
Quote in the paperSubstantial claim- Rests on an assumption: The five sites studied are sufficiently diverse and exemplary to yield recommended practices that are useful to other institutions.
- Interpretationcitation
Decision support is an intensely local phenomenon.
“As evidenced in the case studies, however, decision support is an intensely local phenomenon, 26 and as such, sites may need to tailor or selectively adopt these practices to develop solutions that work for them.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [26]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning
Careful consideration of governance issues when developing and implementing CDS can be as important as the quality of the decision support itself.
“Careful consideration of governance issues when developing and implementing CDS can be as important as the quality of the decision support itself.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Organizations with internally developed systems are responsible for the entire process of development, implementation, and ongoing management and assessment.
“In contrast, organizations with internally developed systems are responsible for the entire process of development, implementation, and ongoing management and assessment.”
Quote in the paperSubstantial claim
- May combine two claims. 26
- Classified as probably not a substantial claim. 43
May combine two claims.
Findingown dataSome organizations carried out an annual review, while other organizations reviewed content based on user feedback or as new evidence became available.
“Some organizations carried out an annual review, while other organizations reviewed content based on user feedback or as new evidence became available.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenDesign changes that affect clinical content at MVIPA are reviewed by the medical director of information systems.
“Design changes that affect clinical content are reviewed by the medical director of information systems.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataInternally developed clinical information systems permit customization, although standardization may be preferred.
“Permitted, although standardization may be preferred”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingnone givenThe VA emphasizes standard practice and common data elements within and across their system of care, and is in the process of standardizing such practices when there is evidence or experience to support such efforts.
“The VA also emphasizes standard practice and common data elements within and across their system of care, and is in the process of standardizing such practices when there is evidence or experience to support such efforts.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingnone givenCommon metrics included firing rate, acceptance rate, analysis of override reasons, and measurement of the decision support's effects on intermediate processes, and ultimately its effects on patient safety and quality of care.
“Common metrics included firing rate, acceptance rate, analysis of override reasons, and measurement of the decision support's effects on intermediate processes, and ultimately its effects on patient safety and quality of care.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenEvidence-based guidelines from nationally recognized authorities are reviewed regularly for inclusion at the VA.
“Evidence-based guidelines from nationally recognized authorities are also reviewed regularly for inclusion.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingnone givenVendor-based clinical information systems have all or almost all content come from the content vendor, and system operations may be run locally.
“All or almost all content comes from content vendor; system operations”
- Also stated in: § CONCLUSIONS · hedged
“may be run locally”
Quote in the paperSubstantial claim- Also stated in: § CONCLUSIONS · hedged
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe five sites studied were quite diverse.
“The five sites we studied were quite diverse; however, they had also learned many overlapping and complementary lessons about governance for CDS.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingnone givenContent at MVIPA is updated periodically through the NextGen release cycle and is first tested by MVIPA staff.
“Content is updated periodically through the NextGen release cycle and is first tested by MVIPA staff.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAll sites reported some form of ongoing content review, but the frequency and regularity of these reviews varied.
“All sites reported some form of ongoing content review, but the frequency and regularity of these reviews varied.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingnone givenVanderbilt conducts regular reviews of content and updates content as clinical evidence surfaces that would necessitate a change.
“Vanderbilt conducts regular reviews of content and then updates the content as clinical evidence surfaces that would necessitate a change.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingnone givenThe director also monitors regulatory requirements and prioritizes updates according to their effective dates and their impact.
“The director also monitors regulatory requirements and prioritizes updates according to their effective dates and their impact.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingnone givenThe Practice Plan conducts surveys of clinical users and creates monthly reports that provide all clinics with a breakdown of utilization of all aspects of the EHR.
“The Practice Plan conducts surveys of clinical users and creates monthly reports that provide all clinics with a breakdown of the utilization of all aspects of the EHR (electronic health record) (eg, percentage of prescriptions written electronically).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn some cases, content was purchased from an outside vendor; in others it was developed by in-house staff based on institutional needs.
“In some cases, content was purchased from an outside vendor, and in others it was developed by inhouse staff based on institutional needs.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenCDS capabilities at the VA are constantly updated and revised to reflect internal research activities, review of performance measures, input from regulatory groups, networking with academic affiliates, changing emphasis of national program and patient priorities, and involvement in national professional societies and working groups.
“CDS capabilities at the VA are constantly being updated and revised to reflect internal research activities, review of performance measures, input from regulatory groups, networking with academic affiliates, changing emphasis of national program and patient priorities, and involvement in national professional societies and working groups.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenVanderbilt prioritizes changes based on quality, safety, clinical volumes, and cost/benefit.
“Vanderbilt prioritizes changes based on quality, safety, clinical volumes, and cost/benefit.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataSites mentioned and underscored the importance of field-testing content and listening and responding to user feedback.
“Sites also mentioned and underscored the importance of fieldtesting content and listening and responding to user feedback.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenAt MVIPA, the primary method of evaluating the effectiveness of CDS is ongoing field testing.
“Finally, at MVIPA, the primary method of evaluating the effectiveness of CDS is ongoing field testing.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe VA national pharmacy program is pursuing integration of a commercially available database for drug-drug/allergy interactions, which would be maintained and periodically updated.
“Additionally, the VA national pharmacy program is pursuing integration of a commercially available database for drugedrug/allergy interactions, which would be maintained and periodically updated.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingnone givenUniversity of Texas, Houston Physicians' Practice Plan relies heavily on Allscripts' content, and updates are tied to Allscripts' release schedule.
“In contrast to the other academic institutions, the University of Texas, Houston Physicians' Practice Plan relies heavily on Allscripts' content, and updates are tied to the Allscripts' release schedule.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenEvaluation of the effectiveness of CDS at the VA is indirect and based on measurement of outcomes it was designed to impact.
“Evaluation of the effectiveness of the CDS is indirect and based on the measurement of outcomes it was designed to impact.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationOutside the healthcare industry, a variety of models have been proposed to describe knowledge management and IT governance practices.
“Outside of the healthcare industry, a variety of models have been proposed to describe knowledge management and IT governance practices.12e14”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites 12e14
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningGovernance can vary widely depending on the type and size of the organization.
“Governance can vary widely depending on the type and size of the organization.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationResearchers note the substantial investment required to implement IT and knowledge management systems and the uncertainty associated with these investments.
“Researchers also note the substantial investment required to implement IT and knowledge management systems and the uncertainty associated with these investments, further underscoring the need for effective governance.12 15”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites 12 15
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
InterpretationreasoningAs a result of limited ability to develop and monitor CDS, most small sites tend to purchase their decision support from commercial content suppliers, rather than developing the content themselves.
“The primary differences are that, in general, most small sites have a limited ability to develop and monitor CDS and, as a result, tend to purchase their decision support from commercial content suppliers, rather than developing the content themselves, and tend to rely on general-purpose software tools and built-in EHR functions.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThe volume of clinical content and rule logic contained in these systems makes tools to monitor CDS inventory necessary for ensuring the system is up to date and functioning properly, and for guiding future development and implementation.
“The volume of clinical content and rule logic contained in these systems makes these tools necessary for ensuring the system is up to date and functioning properly, and for guiding future development and implementation.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductown dataTwo new sites were used to validate and extend the initial findings.
“We then developed questions based on these themes and sent written questionnaires to a purposive sample of five sites: three from our initial site visits and two new sites to validate and extend our initial findings.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningOverall, small sites must confront the same issues as large sites but with the added challenge of limited financial resources and personnel.
“Overall, small sites must confront the same issues but with the added challenge of limited financial resources and personnel.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningMany of the recommended practices may be nearly universal.
“Although the needs of every implementer of decision support are different, we believe that many of these recommended practices may be nearly universal and that all implementers of decision support should consider employing them.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenIn a small practice environment, some tasks, such as monitoring inventory and user feedback, may be simpler to accomplish.
“In a small practice environment, some tasks, such as monitoring inventory and user feedback, may be simpler to accomplish.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningThe governance issues discussed in the paper are not limited to commercial EHR vendors and healthcare institutions.
“The governance issues discussed in this paper are not limited to commercial EHR vendors and healthcare institutions, and in the future, we hope to investigate the role of these additional key plays in CDS development and implementation.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationThe availability and use of special-purpose content management tools, when well designed, can improve efficiency, allow for asynchronous communication, and ensure that content is periodically reviewed and kept up to date.
“The availability and use of these tools, when well designed, can improve efficiency, allow for asynchronous communication, and ensure that content is periodically reviewed and kept up to date.30”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [30]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Rests on an assumption: The development and implementation of effective CDS depend on sound content-management strategies.
- Rests on an assumption: The large knowledge bases required for robust CDS necessitate frequent and thorough management to keep clinical content up to date.
May combine two claims.
Study design and conductreasoningThe five exemplary sites presented are purposefully nonrepresentative of typical practice, which limits the generalizability of the data.
“First, we presented data on a total of five exemplary sites which are purposefully nonrepresentative of typical practicedwe believe that this approach maximized what we could learn, but it also limits the generalizability of our data.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Premisenone givenLarge organizations can potentially develop and implement CDS internally, while smaller organizations may need to rely on a partnership with a commercial vendor.
“For example, large organizations, such as academic medical centers and governmentrun hospitals, can potentially develop and implement CDS internally, while smaller organizations, such as group practices and community hospitals, may need to rely on a partnership with a commercial vendor.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningMeasurement allows content developers to assess the impact of their content and to identify opportunities for improvement.
“Measurement allows content developers to assess the impact of their content and to identify opportunities for improvement.”
Quote in the paperSubstantial claim- Rests on an assumption: Monitoring of CDS interventions is necessary for properly assessing the impact of CDS on clinician behavior and patient care.
Probably not a substantial claim: may not pass S2 (checkable), S4 (based).
Premisenone givenKnowledge bases that are developed must reflect both universal best practices and local practices and needs.
“The knowledge bases that are developed must reflect both universal best practices and local practices and needs.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
InterpretationreasoningSmall sites that are earlier in the process of developing CDS also face similar governance challenges.
“However, small sites that are earlier in the process of developing CDS also face similar governance challenges.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataThe sites studied included only US institutions, which further limits the generalizability of the findings.
“Finally, the sites studied included only US institutions, which further limits the generalizability of our findingsdfuture study of an internationally representative collection of sites is also likely to be fruitful.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningEmploying better governance practices throughout the design and implementation phases, such as increased end-user involvement, can potentially stave off these types of problems.
“Employing better governance practices throughout the design and implementation phases, such as increased end-user involvement, can potentially stave off these types of problems.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
Interpretationnone givenDelivering excellent CDS requires addressing many governance issues.
“Delivering excellent CDS requires addressing many governance issues.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningSpecial-purpose content management tools can enhance the auditability of content, as decisions can be traced.
“Such tools can also enhance the auditability of content, as decisions can be traced.”
Quote in the paperNot a substantial claim- Rests on an assumption: The development and implementation of effective CDS depend on sound content-management strategies.
Classified as probably not a substantial claim.
Study design and conductown dataThe study used a purposive sampling strategy selecting five exemplary institutions with a history of successful CDS research and utilization.
“Our sampling strategy for these visits was purposive; we selected five exemplary institutions with a history of successful CDS research and utilization.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThese models emphasize the need for continuous knowledge management, the value of studying real-world governance best practices, and the importance of well-planned implementation.
“These models emphasize the need for continuous knowledge management, the value of studying real-world governance best practices and the importance of well-planned implementation.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites 12e14
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningGovernance processes take many forms.
“These governance processes take many forms.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductreasoningThe recommended practices were identified based on consensus and expert opinion, and as a result, some effective practices may have been missed.
“We identified recommended practices based on consensus and expert opinion, and as a result, some effective practices may have been missed.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based). May combine two claims.
Premisenone givenKnowledge management is an iterative process that involves both the creation of new content and the continuous review and revision of existing content.
“Knowledge management is an iterative process that involves both the creation of new content and the continuous review and revision of existing content.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Interpretationnone givenIn general, most small sites have a limited ability to develop and monitor CDS.
“The primary differences are that, in general, most small sites have a limited ability to develop and monitor CDS and, as a result, tend to purchase their decision support from commercial content suppliers, rather than developing the content themselves, and tend to rely on general-purpose software tools and built-in EHR functions.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductreasoningThe authors were not able to characterize the cost of CDS governance, or to study the financial implications of different governance approaches.
“Finally, we were not able to characterize the cost of CDS governance, or to study the financial implications of different governance approaches.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
InterpretationreasoningThe present relative paucity of sites with advanced or even formal governance structures may make it premature to perform a study to more rigorously quantify the methods for and value of governance.
“Because of the present relative paucity of sites with advanced (or even formal) governance structures, it may yet be premature to perform such a study, but once there exists a sufficient set of institutions with reasonably robust governance practices, we believe that such a study would add great value to the literature.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationMany rules interact, and as more rules are added, interactions become more frequent.
“A related issue is that many rules interact, and as more rules are added, interactions become more frequent, one example being rules relating to reducing cholesterol levels in patients with diabetes and coronary disease.28”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [28]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S4 (based). May combine two claims.
Premisenone givenFormal governance models for decision support are relatively new, no interventional or wide-scale observational evidence exists for the effect of various CDS governance practices, and there is no particular regulation relevant to such practices.
“Because formal governance models for decision support are relatively new, no interventional (or even wide-scale observational) evidence exists for the effect of various CDS governance practices, and there is no particular regulation relevant to such practices.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
PremisecitationA broad understanding of the institutional pressures organizations face and real-world assessment of these institutional pressures is valuable and necessary to establish effective governance practices and realize the potential of IT and knowledge management systems.
“In order to establish effective governance practices and realize the potential of IT and knowledge management systems, a broad understanding of the institutional pressures organizations face and real-world assessment of these institutional pressures is both valuable and necessary.16”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [16]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningSites may need to tailor or selectively adopt these practices to develop solutions that work for them.
“As evidenced in the case studies, however, decision support is an intensely local phenomenon, 26 and as such, sites may need to tailor or selectively adopt these practices to develop solutions that work for them.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe research team identified themes in the data using a grounded theory approach.
“The research team, lead by trained ethnographers, identified themes in the data using a grounded theory approach.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
The five sites studied are sufficiently diverse and exemplary to yield recommended practices that are useful to other institutions.
“Our sampling strategy for these visits was purposive; we selected five exemplary institutions with a history of successful CDS research and utilization.”
The paper relies on this without support.
Effective CDS often requires extremely large knowledge bases of clinical facts.
“Effective CDS often requires extremely large knowledge bases of clinical facts (eg, drug-interaction tables).”
The paper relies on this without support.
The development and implementation of effective CDS depend on sound content-management strategies.
“The development and implementation of effective CDS also depend on sound content-management strategies.”
The paper relies on this without support.
The large knowledge bases required for robust CDS necessitate frequent and thorough management to keep clinical content up to date.
“The large knowledge bases required for robust CDS necessitate frequent and thorough management in order to keep clinical content up to date.”
The paper relies on this without support.
A seemingly minor change can have a major impact on how many warnings are being delivered and on overall system performance.
“Often, a seemingly minor change can have a major impact on how many warnings are being delivered, and even on overall system performance.”
The paper relies on this without support.
Listening and responding to feedback is an important tool for product improvement.
“Listening and responding to feedback is an important tool for product improvement.”
The paper relies on this without support.
User feedback fosters a sense of ownership of the product by end users when they feel that their input is valued.
“It also has the added advantage of fostering a sense of ownership of the product by end users when they feel that their input is valued.”
The paper relies on this without support.
Monitoring of CDS interventions is necessary for properly assessing the impact of CDS on clinician behavior and patient care.
“In addition to ongoing monitoring of CDS inventory (as outlined in Recommendation 3), monitoring of CDS interventions is necessary for properly assessing the impact of CDS on clinician behavior and patient care.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Effective governance of CDS has been demonstrated in other institutions, resulting in the transition of alert and reminder content to other more appropriate areas in the EHR, downgrading the severity of alerts, and assessing the effect of CDS on clinician behavior and patient care.
“Effective governance of CDS has been demonstrated in other institutions, resulting in the transition of alert and reminder content to other more appropriate areas in the EHR, downgrading the severity of alerts (often leading to them no longer firing), 38 39 and assessing the effect of CDS on clinician behavior and patient care. 40 41”
From Qualitative Study of Inpatient Hospital Medicine Interruptive Alerts and Clinical Decision Support (2026) · cites this paper as [40]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredOur findings assessing interruptive alert helpfulness and recommendations to change interruptive alert presentation, timing, and targeting were also like those found in previous studies.
“Our findings assessing interruptive alert helpfulness and recommendations to change interruptive alert presentation, timing, and targeting were also like those found in previous studies. 35 36 40”
From Qualitative Study of Inpatient Hospital Medicine Interruptive Alerts and Clinical Decision Support (2026) · cites this paper as [40]
The sections on ongoing monitoring and user feedback (pages not specified in our copy) describe assessing responses to alerts and using feedback to improve decision support, including interface changes. They do not specifically recommend changing the presentation, timing, and targeting of interruptive alerts or assess their helpfulness as such. (LLM, conf=0.82)
Experimental — accuracy not yet measuredA key challenge with clinical decision support is knowledge management as guidelines and best practices change over time, as well as governance.
“A key challenge with clinical decision support is knowledge management as guidelines and best practices change over time,40–42 as well as governance.43–45”
From Clinician collaboration to improve clinical decision support: the Clickbusters initiative (2022) · cites this paper as [43]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Same article is cited with different publication years
MinorReferences 6 and 30 give the same authors, title, journal, volume, and pages, but cite different publication years: 2009 and 2010.
“6. Sittig DF, Wright A, Simonaitis L, et al. The state of the art in clinical knowledge management: an inventory of tools and techniques. Int J Med Inform 2009;79:44e57.”
“30. Sittig DF, Wright A, Simonaitis L, et al. The state of the art in clinical knowledge management: an inventory of tools and techniques. Int J Med Inform 2010;79(1):44e57.”
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Self-citationThe Value of Monitoring Clinical Decision Support Interventions
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Self-citationMeasuring nursing benefits of an electronic medical record system: A scoping review
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User stories as lightweight requirements for agile clinical decision support development
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Self-citationAudit and feedback of antibiotic use
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Enhancing Diagnosis Through Technology
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Self-citationRights and responsibilities of users of electronic health records
Sittig, D. F., & Singh, H. (2012) · Canadian Medical Association Journal · doi:10.1503/cmaj.111599 · Cited by 28 · see citing works
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Self-citationHealth Information Systems in Small Practices
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Data Warehouse Governance Programs in Healthcare Settings: A Literature Review and a Call to Action
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Alerts in Clinical Decision Support Systems (CDSS): A Bibliometric Review and Content Analysis
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Utilizing an integrated infrastructure for outcomes research: a systematic review
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Clinical Decision Support for Laboratory Testing
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Issues and Limitations on the Road to Fair and Inclusive AI Solutions for Biomedical Challenges
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Clinical governance, corporate social responsibility, health service quality, and brand equity
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Clinical Decision Support for Colon and Rectal Surgery: An Overview
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Self-citationEvidence-Based Clinical Decision Support
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Self-citationImproving the specificity of drug-drug interaction alerts: Can it be done?
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Self-citationToward More Proactive Approaches to Safety in the Electronic Health Record Era
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Using lean methodology to improve efficiency of electronic order set maintenance in the hospital
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Interests and needs of eye care providers in clinical decision support for glaucoma
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Clinical Decision Support Systems: A Visual Survey
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Drug-Drug Interaction Alerts: Emphasizing the Evidence
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Measuring agreement between decision support reminders: the cloud vs. the local expert
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Self-citationAssessing the perception of information components in financial decision support systems
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Advancing Healthcare AI Governance: A Comprehensive Maturity Model Based on Systematic ReviewPreprint
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A Clinical Knowledge Management Program
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Redesigning Clinical Decision Support for Retinopathy of Prematurity Screening After Alert Failure
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Clinical Decision Support: It’s More than Just Alerts
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COVID-19 and the Electronic Health Record: Tool Design and Evolution at the U.S. Pandemic Epicenter
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Clinical Decision Support Systems Governance and the Pharmacy Department
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Clinical Decision Support Malfunctions
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Safety Considerations in Ambulatory Care Informatics
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Self-citationGovernance for Clinical Decision Support
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Self-citationUnexpected Drawbacks of Electronic Order Sets
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Operationalizing ethical AI for safe clinical integration: A qualitative interview study
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- Authors
- Wright, A., Sittig, D. F., Ash, J. S., Bates, D. W., Feblowitz, J., Fraser, G., Maviglia, S. M., McMullen, C., Nichol, W. P., Pang, J. E., Starmer, J., & Middleton, B.
- Affiliations
- Brigham and Women's Hospital (US)
- Memorial Hermann (US)
- Oregon Health & Science University (US)
- Kaiser Permanente Center for Health Research (US)
- University of Washington (US)
- Vanderbilt University Medical Center (US)
- Corresponding author
- Wright, A.
- Venue
- Journal of the American Medical Informatics Association
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-03-01
- Volume
- 18
- Issue
- 2
- Pages
- 187-194
- ISSN
- 1067-5027 (ISSN-L)
- 1527-974X
- PMC
- PMC3116253
- OpenAlex
- W2096222958
- Semantic Scholar
- e4a7710aaaf5c6257bc3edc6e57e12cfc045188f
- Cited by
- 92
- References
- 36
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 3 · 2023: 3 · 2022: 8 · 2021: 4 · 2020: 4 · 2019: 9 · 2018: 6 · 2017: 5 · 2016: 8 · 2015: 7 · 2014: 5 · 2013: 13 · 2012: 4
- FWCI
- 12.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of the American Medical Informatics Association (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Kaiser Permanente
- Agency for Healthcare Research and Quality (HHSA290200810010)
- U.S. National Library of Medicine (R56LM006942, 563 R56-LM006942)
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
- Keywords
- clinical decision support, clinical governance, technical governance, content management, clinical information systems, patient safety, quality of care, hospitals
- MeSH terms
- Health Plan Implementation, Humans, Quality Assurance, Health Care, United States, Organizational Case Studies, Decision Support Systems, Clinical
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