Warfarin reversal

Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT)

Palareti, G., Leali, N., COCCHERI, S., Poggi, M., Manotti, C., D’Angelo, A., Pengo, V., Erba, N., Moia, M., CIAVARELLA, N., et al. (1996) · The Lancet · doi:10.1016/s0140-6736(96)01109-9 · Cited by 1,319 · see citing works

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

Aithal, G. P., Day, C. P., Kesteven, P. J., & Daly, A. K. (1999) · The Lancet · doi:10.1016/s0140-6736(98)04474-2 · Cited by 1,239 · see citing works

Risk Factors for Intracranial Hemorrhage in Outpatients Taking Warfarin

Hylek, E. M., & Singer, D. E. (1994) · Annals of Internal Medicine · doi:10.7326/0003-4819-120-11-199406010-00001 · Cited by 915 · see citing works

Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention

Landefeld, C. S., & Beyth, R. J. (1993) · The American Journal of Medicine · doi:10.1016/0002-9343(93)90285-w · Cited by 897 · see citing works

Prospective evaluation of an index for predicting the risk of major bleeding in outpatients treated with warfarin

Beyth, R. J., Quinn, L., & Landefeld, C. S. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(98)00198-3 · Cited by 777 · see citing works

Risk Factors for Complications of Chronic Anticoagulation: A Multicenter Study

Fihn, S. D., McDonell, M., Martin, D., Henikoff, J. G., Vermes, D., Kent, D., White, R. H., & for the Warfarin Optimized Outpatient Follow-up Study Group* (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-118-7-199304010-00005 · Cited by 670 · see citing works

Managing Oral Anticoagulant Therapy

Ansell, J., Hirsh, J., Dalen, J. E., Bussey, H. I., Anderson, D., Poller, L., Jacobson, A. K., Deykin, D., & Matchar, D. B. (2001) · CHEST Journal · doi:10.1378/chest.119.1_suppl.22s · Cited by 576 · see citing works

Oral Anticoagulants and Intracranial Hemorrhage

Hart, R. G., Boop, B. S., & Anderson, D. C. (1995) · Stroke · doi:10.1161/01.str.26.8.1471 · Cited by 545 · see citing works

Bleeding complications in oral anticoagulant therapy. An analysis of risk factors

van der Meer, F. J. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.153.13.1557 · Cited by 539 · see citing works

Bleeding Complications in Oral Anticoagulant Therapy

van der Meer, F. J. M. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.1993.00410130073007 · Cited by 435 · see citing works

Emergency Oral Anticoagulant Reversal: The Relative Efficacy of Infusions of Fresh Frozen Plasma and Clotting Factor Concentrate on Correction of the Coagulopathy

Makris, M., Greaves, M., Phillips, W. S., Kitchen, S., Rosendaal, F. R., & Preston, F. E. (1997) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1655992 · Cited by 397 · see citing works

Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment

Taube, J. M., Halsall, D. J., & Baglin, T. P. (2000) · Blood · doi:10.1182/blood.v96.5.1816 · Cited by 382 · see citing works

MRI evidence of past cerebral microbleeds in a healthy elderly population

Roob, G., Schmidt, R., Kapeller, P., Lechner, A., Hartung, H., & Fazekas, F. (1999) · Neurology · doi:10.1212/wnl.52.5.991 · Cited by 363 · see citing works

Guidelines on oral anticoagulation: third edition

(1998) · British Journal of Haematology · doi:10.1046/j.1365-2141.1998.00715.x · Cited by 314 · see citing works

Warfarin-associated hemorrhage and cerebral amyloid angiopathy

Rosand, J., Hylek, E. M., O’Donnell, H. C., & Greenberg, S. M. (2000) · Neurology · doi:10.1212/wnl.55.7.947 · Cited by 309 · see citing works

Major bleeding during anticoagulation after cerebral ischemia

Gorter, J. W., (SPIRIT), F. T. S. P. I. R. I. T., & Groups, E. A. F. T. (. S. (1999) · Neurology · doi:10.1212/wnl.53.6.1319 · Cited by 307 · see citing works

Can Patients Be Anticoagulated After Intracerebral Hemorrhage?

Eckman, M. H., Rosand, J. M., Knudsen, K. A., Singer, D. E., & Greenberg, S. M. (2003) · Stroke · doi:10.1161/01.str.0000078311.18928.16 · Cited by 300 · see citing works

Emergency reversal of anticoagulation after intracerebral hemorrhage.

Fredriksson, K. A., Norrving, B. G., & Strömblad, L. ‐. (1992) · Stroke · doi:10.1161/01.str.23.7.972 · Cited by 295 · see citing works

Temporary Discontinuation of Warfarin Therapy: Changes in the International Normalized Ratio

White, R. H. R., McKittrick, T., Hutchinson, R., & Twitchell, J. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-1-199501010-00006 · Cited by 279 · see citing works

Reversal of Warfarin-Induced Excessive Anticoagulation with Recombinant Human Factor VIIa Concentrate

Deveras, R. A. E., & Kessler, C. M. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-11-200212030-00009 · Cited by 276 · see citing works

Interindividual variability in sensitivity to warfarin-Nature or nurture?

Loebstein, R. (2001) · Clinical Pharmacology & Therapeutics · doi:10.1067/mcp.2001.117444 · Cited by 261 · see citing works

Management and Prognostic Features of Intracerebral Hemorrhage During Anticoagulant Therapy: A Swedish Multicenter Study

Sjöblom, L., Hårdemark, H., Lindgren, A., Norrving, B. G., Fahlén, M., Samuelsson, M., Stigendal, L., Stockelberg, D., Taghavi, A., Wallrup, L., et al. (2001) · Stroke · doi:10.1161/hs1101.098523 · Cited by 228 · see citing works

Prothrombin complex concentrate for oral anticoagulant reversal in neurosurgical emergencies

Cartmill, G. D. M. (2000) · British Journal of Neurosurgery · doi:10.1080/02688690050175265 · Cited by 222 · see citing works

Use of Factor IX Complex in Warfarin-related Intracranial Hemorrhage

Boulis, N. M., Bobek, M. P., Schmaier, A. H., & Hoff, J. T. (1999) · Neurosurgery · doi:10.1097/00006123-199911000-00020 · Cited by 213 · see citing works

The risk of intracerebral hemorrhage during oral anticoagulant treatment: A population study

Wintzen, A. R., de Jonge, H., Loeliger, E. A., & Bots, G. T. A. M. (1984) · Annals of Neurology · doi:10.1002/ana.410160505 · Cited by 213 · see citing works

A comparison of the efficacy and rate of response to oral and intravenous Vitamin K in reversal of over‐anticoagulation with warfarin

Watson, H. G., Baglin, T. P., Laidlaw, S., Makris, M., & Preston, F. E. (2001) · British Journal of Haematology · doi:10.1046/j.1365-2141.2001.03070.x · Cited by 204 · see citing works

Safety of Discontinuation of Anticoagulation in Patients With Intracranial Hemorrhage at High Thromboembolic Risk

Phan, T. G., Koh, M., & Wijdicks, E. F. M. (2000) · Archives of Neurology · doi:10.1001/archneur.57.12.1710 · Cited by 198 · see citing works

Leukoaraiosis is associated with warfarin-related hemorrhage following ischemic stroke

Smith, E. E., Rosand, J. M., Knudsen, K. A., Hylek, E. M., & Greenberg, S. M. (2002) · Neurology · doi:10.1212/wnl.59.2.193 · Cited by 194 · see citing works

Rapid reversal of oral anticoagulation with warfarin by a prothrombin complex concentrate (Beriplex): efficacy and safety in 42 patients

Preston, F. E., Laidlaw, S. T., Sampson, B., & Kitchen, S. (2002) · British Journal of Haematology · doi:10.1046/j.0007-1048.2001.03295.x · Cited by 188 · see citing works

Reversal of the International Normalized Ratio with recombinant activated factor VII in central nervous system bleeding during warfarin thromboprophylaxis

Sørensen, B., Johansen, P., Nielsen, G., Sørensen, J. C. H., & Ingerslev, J. (2003) · Blood Coagulation & Fibrinolysis · doi:10.1097/00001721-200307000-00007 · Cited by 177 · see citing works

Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial

Crowther, M. A., Julian, J. A., McCarty, D., Douketis, J. D., Kovacs, M. J., Biagoni, L., Schnurr, T., McGinnis, J., Gent, M., Hirsh, J., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03125-1 · Cited by 173 · see citing works

Prognostic parameters in spontaneous intracerebral hematomas with special reference to anticoagulant treatment.

Rådberg, J., Olsson, J. E., & Rådberg, C. (1991) · Stroke · doi:10.1161/01.str.22.5.571 · Cited by 171 · see citing works

The effect of recombinant factor VIIa (NovoSeven???) in healthy volunteers receiving acenocoumarol to an International Normalized Ratio above 2.0

Erhardtsen, E., Nony, P., DECHAVANNE, M., Ffrench, P., Boissel, J., & Hedner, U. K. E. (1998) · Blood Coagulation & Fibrinolysis · doi:10.1097/00001721-199811000-00003 · Cited by 167 · see citing works

The Dilemma of Discontinuation of Anticoagulation Therapy for Patients with Intracranial Hemorrhage and Mechanical Heart Valves

Wijdicks, E. F. M., Schievink, W. I., Brown, R. D., & Mullany, C. J. (1998) · Neurosurgery · doi:10.1097/00006123-199804000-00053 · Cited by 159 · see citing works

Thrombogenicity of Prothrombin Complex Concentrates

Köhler, M. (1999) · Thrombosis Research · doi:10.1016/s0049-3848(99)00079-1 · Cited by 159 · see citing works

Increased Risk of Intracranial Hemorrhage when Aspirin Is Combined with Warfarin: A Meta-Analysis and Hypothesis

Hart, R. G., Benavente, O., & Pearce, L. A. (1999) · Cerebrovascular Diseases · doi:10.1159/000015958 · Cited by 149 · see citing works

The management of coumarin‐induced over‐anticoagulation

Makris, M., & Watson, H. G. (2001) · British Journal of Haematology · doi:10.1046/j.1365-2141.2001.02908.x · Cited by 142 · see citing works

The use of recombinant activated factor VII to reverse warfarin-induced anticoagulation in patients with hemorrhages in the central nervous system: preliminary findings

Lin, J., Hanigan, W. C., Tarantino, M. D., & Wang, J. C. K. (2003) · Journal of neurosurgery · doi:10.3171/jns.2003.98.4.0737 · Cited by 137 · see citing works

Predisposing factors for enlargement of intracerebral hemorrhage in patients treated with warfarin

Minematsu, K., Naritomi, H., Sakata, T., Yamaguchi, T., & Yasaka, M. (2003) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1613443 · Cited by 134 · see citing works

Beriplex P/N reverses severe warfarin‐induced overanticoagulation immediately and completely in patients presenting with major bleeding

Evans, G., Luddington, R. J., & Baglin, T. P. (2001) · British Journal of Haematology · doi:10.1046/j.1365-2141.2001.03214.x · Cited by 133 · see citing works

Correction of Excessive Anticoagulation with Low-Dose Oral Vitamin K1

Weibert, R. T., Le, D. T., Kayser, S. R., & Rapaport, S. I. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-126-12-199706150-00005 · Cited by 122 · see citing works

Effective Reversal of Warfarin-lnduced Excessive Anticoagulation with Low Dose Mtamin K1

Shetty, H. G. M., Backhouse, G., Bentley, D. P., & Routledge, P. (1992) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1648371 · Cited by 120 · see citing works

Complications of Preinjury Warfarin Use in the Trauma Patient

Mina, A. A., Bair, H. A., Howells, G. A., & Bendick, P. J. (2003) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/01.ta.0000063271.05829.15 · Cited by 112 · see citing works

A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism.

Chu, K. C., Wu, S. M., Stanley, T. E., Stafford, D. W., & High, K. A. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118956 · Cited by 106 · see citing works

Effective reversal of warfarin-induced excessive anticoagulation with low dose vitamin K1.

Shetty, H. G. M., Backhouse, G., Bentley, D. P., et al. (1992) · PubMed · Cited by 106 · see citing works

Missense mutations at ALA‐10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy

Oldenburg, J., Quenzel, E., Harbrecht, U., Fregin, A., Kreß, W., Müller, C. R., Hertfelder, H.-J., Schwaab, R., Brackmann, H., & Hanfland, P. (1997) · British Journal of Haematology · doi:10.1046/j.1365-2141.1997.2213036.x · Cited by 96 · see citing works

Restarting anticoagulation in prosthetic heart valve patients after intracranial haemorrhage: a 2‐year follow‐up

Butler, & Tait, R. C. (1998) · British Journal of Haematology · doi:10.1046/j.1365-2141.1998.01078.x · Cited by 94 · see citing works

Differential effects of 2C9*3 and 2C9*2 variants of cytochrome P-450 CYP2C9 on sensitivity to acenocoumarol

Hermida, J., Zarza, J., Alberca, I., Montes, R., López, M. L., Molina, E., & Rocha, E. (2002) · Blood · doi:10.1182/blood.v99.11.4237 · Cited by 85 · see citing works

Recombinant coagulation factor VIIa for rapid preoperative correction of warfarin-related coagulopathy in patients with acute subdural hematoma.

Veshchev, I., Elran, H., & Salame, K. (2002) · PubMed · Cited by 83 · see citing works

Randomized, Placebo‐Controlled Trial of Oral Phytonadione for Excessive Anticoagulation

Patel, R. J., Witt, D. M., Saseen, J. J., Tillman, D. J., & Wilkinson, D. S. (2000) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.20.15.1159.34585 · Cited by 80 · see citing works

Reversal of excessive effect of regular anticoagulation

Pengo, V., Banzato, A., Garelli, E., Zasso, A., & Biasiolo, A. (1993) · Blood Coagulation & Fibrinolysis · doi:10.1097/00001721-199304050-00010 · Cited by 80 · see citing works

Prediction of Functional Outcome and In-Hospital Mortality After Admission With Oral Anticoagulant–Related Intracerebral Hemorrhage

Berwaerts, J., Dijkhuizen, R. S., Robb, O. J., & Webster, J. (2000) · Stroke · doi:10.1161/01.str.31.11.2558 · Cited by 78 · see citing works

Analysis of risk factors involved in oral-anticoagulant-related intracranial haemorrhages

Berwaerts, J. (2000) · QJM · doi:10.1093/qjmed/93.8.513 · Cited by 76 · see citing works

Treating Thrombosis in the 21st Century

Shapiro, S. S. (2003) · New England Journal of Medicine · doi:10.1056/nejme038152 · Cited by 75 · see citing works

Evaluation of Excessive Anticoagulation in a Group Model Health Maintenance Organization

Lousberg, T. R., Witt, D. M., Beall, D. G., Carter, B. L., & Malone, D. C. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.5.528 · Cited by 70 · see citing works

Determination of bleeding risk using genetic markers in patients taking phenprocoumon

Hummers, E., Hess, S., Adham, I. M., Papke, T., Pieske, B. M., & Kochen, M. M. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0580-8 · Cited by 60 · see citing works

Management of intracranial bleeding associated with anticoagulation: balancing the risk of further bleeding against thromboembolism from prosthetic heart valves

Crawley, F. (2000) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.69.3.396 · Cited by 58 · see citing works

A prospective randomized study to determine the optimal dose of intravenous vitamin K in reversal of over‐warfarinization

Hung, A., Singh, S., & Tait, R. C. (2000) · British Journal of Haematology · doi:10.1046/j.1365-2141.2000.02001.x · Cited by 57 · see citing works

Low Dose Oral Vitamin K to Reverse Acenocoumarol-induced Coagulopathy: A Randomized Controlled Trial

Crowther, M. A., Steidl, L., Ultori, C., Mera, V., Dentali, F., Squizzato, A., Marchesi, C., Venco, A., & Ageno, W. (2002) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1613152 · Cited by 49 · see citing works

Effect of prothrombin complex concentrate on INR and blood coagulation system in emergency patients treated with warfarin overdose

Yasaka, M., Oomura, M., Ikeno, K., Naritomi, H., & Minematsu, K. (2003) · Annals of Hematology · doi:10.1007/s00277-002-0568-y · Cited by 49 · see citing works

Clinical experience with the use of clotting factor concentrates in oral anticoagulation reversal

Nitu, I. C., Perry, D., & Lee, C. A. (1998) · Clinical & Laboratory Haematology · doi:10.1046/j.1365-2257.1998.00161.x · Cited by 47 · see citing works

Genetic control of anticoagulation

Mannucci, P. M. (1999) · The Lancet · doi:10.1016/s0140-6736(98)00326-2 · Cited by 46 · see citing works

The incidence of bleeding complications associated with warfarin treatment in general practice in the United Kingdom.

Hollowell, J., Ruigómez, A., Johansson, S., Wallander, M.-A. A., & García‐Rodríguez, L. A. (2003) · Europe PMC (PubMed Central) · Cited by 46 · see citing works

THE EFFECTIVENESS OF AN ORAL VITAMIN K1 IN CONTROLLING EXCESSIVE HYPOPROTHROMBINEMIA DURING ANTICOAGULANT THERAPY

Cosgriff, S. W. (1956) · Annals of Internal Medicine · doi:10.7326/0003-4819-45-1-14 · Cited by 44 · see citing works

Prospective Evaluation of Anticoagulant Reversal With Oral Vitamin K1 While Continuing Warfarin Therapy Unchanged

Wentzien, T. H., O’Reilly, R. A., & Kearns, P. J. (1998) · CHEST Journal · doi:10.1378/chest.114.6.1546 · Cited by 32 · see citing works

Low-Dose Vitamin K Therapy in Excessively Anticoagulated Patients: A Dose-Finding Study

Brophy, M. T., Fiore, L. D., & Deykin, D. (1997) · Journal of Thrombosis and Thrombolysis · doi:10.1023/a:1008811421946 · Cited by 26 · see citing works

Treatment of Warfarin-Associated Coagulopathy

Wilson, S. E., Douketis, J. D., & Crowther, M. A. (2001) · CHEST Journal · doi:10.1378/chest.120.6.1972 · Cited by 26 · see citing works

The Potential Role of Direct Thrombin Inhibitors in the Prevention and Treatment of Venous Thromboembolism

Heit, J. A. (2003) · CHEST Journal · doi:10.1378/chest.124.3_suppl.40s · Cited by 20 · see citing works

The Efficacy of rHuEPO in Cancer‐Related Anaemia

Samol, J., & Littlewood, T. J. (2003) · British Journal of Haematology · doi:10.1046/j.1365-2141.2003.04129.x · Cited by 20 · see citing works

Major Bleeding Caused by Warfarin in a Genetically Susceptible Patient

Bloch, A., Ben‐Chetrit, E., Muszkat, M., & Caraco, Y. (2002) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.22.1.97.33491 · Cited by 19 · see citing works

The use of oral vitamin K for reversal of over‐warfarinization

Pendry, K., Bhavnani, M., & Shwe, K. H. (2001) · British Journal of Haematology · doi:10.1046/j.1365-2141.2001.02804.x · Cited by 16 · see citing works

Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms

Rafii, A., McGrath, S. D., Blinder, M. A., Buchman, T. G., Zehnbauer, B. A., & Freeman, B. D. (2001) · American Journal of Hematology · doi:10.1002/ajh.1094 · Cited by 15 · see citing works

The use of vitamin k for reversal of over-warfarinization in children

Bolton‐Maggs, P. H. B., & Brook, L. A. (2002) · British Journal of Haematology · doi:10.1046/j.1365-2141.2002.03631_5.x · Cited by 13 · see citing works

Increased Sensitivity to Warfarin in Elderly Hispanics

Casner, P. R., & Sandoval, E. (2002) · The Journal of Clinical Pharmacology · doi:10.1177/00912700222011175 · Cited by 9 · see citing works

Reversal of coumarin-induced over-anticoagulation

Escobar, M. A. (2002) · British Journal of Haematology · doi:10.1046/j.1365-2141.2002.03631_6.x · Cited by 5 · see citing works

Reply to Escobar

Makris, M., & Watson, H. G. (2002) · British Journal of Haematology · doi:10.1046/j.1365-2141.2002.03631_7.x · Cited by 3 · see citing works

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438 · see citing works

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418 · see citing works

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

Hemphill, J. C., Greenberg, S. M., Anderson, C. S., Becker, K. J., Bendok, B. R., Cushman, M., Fung, G. L., Goldstein, J. N., Macdonald, R. L., Mitchell, P. H., et al. (2015) · Stroke · doi:10.1161/str.0000000000000069 · Cited by 3,992 · see citing works

The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

Costanzo, M. R., Costanzo, M. R., Dipchand, A. I., Starling, R. C., Anderson, A. S., Chan, M. C. Y., Desai, S., Fedson, S., Fisher, P. W., Gonzales-Stawinski, G. V., et al. (2010) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2010.05.034 · Cited by 1,647 · see citing works

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

Morgenstern, L. B., Hemphill, J. C., Anderson, C. S., Becker, K. J., Broderick, J. P., Connolly, E. S., Greenberg, S. M., Huang, J. N., Macdonald, R. L., Messe, S. R., et al. (2010) · Stroke · doi:10.1161/str.0b013e3181ec611b · Cited by 1,486 · see citing works

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403 · see citing works

Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation

Heidbüchel, H., Verhamme, P. B., Alings, M., Antz, M., Diener, H., Hacke, W., Oldgren, J., Sinnaeve, P., Camm, A. J., & Kirchhof, P. F. (2015) · EP Europace · doi:10.1093/europace/euv309 · Cited by 1,114 · see citing works

Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

Frontera, J. A., Lewin, J. J., Rabinstein, A. A., Aisiku, I. P., Alexandrov, A. W., Cook, A. M., del Zoppo, G. J., Kumar, M. A., Peerschke, E. I. B., Stiefel, M., et al. (2015) · Neurocritical Care · doi:10.1007/s12028-015-0222-x · Cited by 713 · see citing works

The surgical management of chronic subdural hematoma

Ducruet, A. F., Grobelny, B. T., Zacharia, B. E., Hickman, Z. L., DeRosa, P., Anderson, K., Sussman, E. S., Carpenter, A. B., & Connolly, E. S. (2011) · Neurosurgical Review · doi:10.1007/s10143-011-0349-y · Cited by 521 · see citing works

The increasing incidence of anticoagulant-associated intracerebral hemorrhage

Flaherty, M. L., D, B. M. K. M., Woo, D., Kleindorfer, D., Alwell, K., Sekar, P., Moomaw, C. J., Haverbusch, M. A., & Broderick, J. P. (2007) · Neurology · doi:10.1212/01.wnl.0000250340.05202.8b · Cited by 477 · see citing works

Therapeutic strategies for thrombosis: new targets and approaches

Mackman, N., Bergmeier, W., Stouffer, G. A., & Weitz, J. I. (2020) · Nature Reviews Drug Discovery · doi:10.1038/s41573-020-0061-0 · Cited by 403 · see citing works

Role of prothrombin complex concentrates in reversing warfarin anticoagulation: A review of the literature

Leissinger, C., Blatt, P. M., Hoots, W. K., & Ewenstein, B. M. (2007) · American Journal of Hematology · doi:10.1002/ajh.21046 · Cited by 343 · see citing works

Hematoma Growth and Outcome in Treated Neurocritical Care Patients With Intracerebral Hemorrhage Related to Oral Anticoagulant Therapy

Huttner, H. B., Schellinger, P. D., Hartmann, M., Köhrmann, M., Jüettler, E., Wikner, J., Mueller, S., Meyding‐Lamadé, U., Strobl, R., Mansmann, U., et al. (2006) · Stroke · doi:10.1161/01.str.0000221786.81354.d6 · Cited by 333 · see citing works

Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial

Glund, S., Stangier, J., Schmohl, M., Ganßer, D., Norris, S. H., van Ryn, J., Lang, B. J., Ramael, S., Moschetti, V., Gruenenfelder, F. I., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60732-2 · Cited by 318 · see citing works

Bleeding risk and the management of bleeding complications in patients undergoing anticoagulant therapy: focus on new anticoagulant agents

Crowther, M. A., & Warkentin, T. E. (2008) · Blood · doi:10.1182/blood-2007-10-120543 · Cited by 311 · see citing works

Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists

Marchesi, C., Giorgi‐Pierfranceschi, M., Crowther, M. A., Garcia, D. A., Hylek, E. M., Witt, D. M., Clark, N. P., Squizzato, A., Imberti, D., Ageno, W., et al. (2011) · Thrombosis and Haemostasis · doi:10.1160/th11-01-0052 · Cited by 306 · see citing works

Intracerebral Hemorrhage Associated With Oral Anticoagulant Therapy

Steiner, T., Rosand, J. M., & Diringer, M. N. (2005) · Stroke · doi:10.1161/01.str.0000196989.09900.f8 · Cited by 294 · see citing works

Evidence based diagnosis and management of chronic subdural hematoma: A review of the literature

Mehta, V. A., Harward, S. C., Sankey, E. W., Nayar, G., & Codd, P. J. (2018) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2018.01.050 · Cited by 240 · see citing works

Prothrombin complex concentrates: an update.

Franchini, M., & Lippi, G. (2010) · Europe PMC (PubMed Central) · doi:10.2450/2010.0149-09 · Cited by 203 · see citing works

Management consensus guidance for the use of rivaroxaban – an oral, direct factor Xa inhibitor

Kreutz, R. H., Llau, J. V., Norrving, B. G., Haas, S. K., & Turpie, A. G. G. (2012) · Thrombosis and Haemostasis · doi:10.1160/th12-03-0209 · Cited by 167 · see citing works

Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications

Heestermans, M., Poénou, G., Hamzeh‐Cognasse, H., Cognasse, F., & Bertoletti, L. (2022) · Cells · doi:10.3390/cells11203214 · Cited by 161 · see citing works

Prothrombin complex concentrate in surgical patients: retrospective evaluation of vitamin K antagonist reversal and treatment of severe bleeding

Schick, K. S., Fertmann, J. M., Jauch, K., & Hoffmann, J. N. (2009) · Critical Care · doi:10.1186/cc8186 · Cited by 125 · see citing works

Progression of warfarin-associated intracerebral hemorrhage after INR normalization with FFP

Lee, S. B., Manno, E. M., Layton, K. F., & Wijdicks, E. F. M. (2006) · Neurology · doi:10.1212/01.wnl.0000238104.75563.2f · Cited by 113 · see citing works

Oral anticoagulant-associated intracerebral hemorrhage

Cervera, Á., Amaro, S., & Chamorro, Á. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6153-3 · Cited by 99 · see citing works

Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study

Hanke, A., Joch, C., & Görlinger, K. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aes501 · Cited by 93 · see citing works

Emergency Neurological Life Support: Intracerebral Hemorrhage

Jauch, E. C., Pineda, J., & Hemphill, J. C. (2015) · Neurocritical Care · doi:10.1007/s12028-015-0167-0 · Cited by 86 · see citing works

Hemostatic and hemorrhagic problems in neurosurgical patients

Gerlach, R., Krause, M., Seifert, V., & Goerlinger, K. (2009) · Acta Neurochirurgica · doi:10.1007/s00701-009-0409-z · Cited by 79 · see citing works

Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation

Dickneite, G. (2006) · Thrombosis Research · doi:10.1016/j.thromres.2006.05.011 · Cited by 79 · see citing works

Hereditary combined deficiency of the vitamin K-dependent clotting factors

Napolitano, M., Mariani, G., & Lapecorella, M. (2010) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-5-21 · Cited by 79 · see citing works

Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathy

Wójcik, C., Schymik, M. L., & Cure, E. G. (2009) · International Journal of Emergency Medicine · doi:10.1007/s12245-009-0125-8 · Cited by 77 · see citing works

Reversal of Elevated International Normalized Ratios and Bleeding with Low‐Dose Recombinant Activated Factor VII in Patients Receiving Warfarin

Dager, W. E., King, J. H., Regalia, R. C., Williamson, D., Gosselin, R. C., White, R. H. R., Tharratt, R. S., & Albertson, T. E. (2006) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.26.8.1091 · Cited by 74 · see citing works

Warfarin-induced bleeding complications — clinical presentation and therapeutic options

Wiedermann, C. J., & Stockner, I. (2008) · Thrombosis Research · doi:10.1016/s0049-3848(08)70004-5 · Cited by 74 · see citing works

Acute Traumatic Brain Injury: Mortality in the Elderly

Herou, E., Romner, B., & Tomasevic, G. (2015) · World Neurosurgery · doi:10.1016/j.wneu.2015.02.023 · Cited by 73 · see citing works

Atrial fibrillation in Sub-Saharan Africa: epidemiology, unmet needs, and treatment options

Stambler, B. S., & Ngunga, L. M. (2015) · International Journal of General Medicine · doi:10.2147/ijgm.s84537 · Cited by 72 · see citing works

Epidemiological characteristics of 778 patients who underwent surgical drainage of chronic subdural hematomas in Brasília, Brazil

Sousa, E. B., Brandão, L. F. D. S., Tavares, C. B., Borges, I. B. C., Neto, N. G. F., & Kessler, I. M. (2013) · BMC Surgery · doi:10.1186/1471-2482-13-5 · Cited by 72 · see citing works

Antivitamins for Medicinal Applications

Zelder, F., Sonnay, M., & Prieto, L. (2015) · ChemBioChem · doi:10.1002/cbic.201500072 · Cited by 71 · see citing works

Exploratory study on the reversal of warfarin with rFVIIa in healthy subjects

Skolnick, B. E., Mathews, D. R., Khutoryansky, N., Pusateri, A. E., & Carr, M. E. (2010) · Blood · doi:10.1182/blood-2009-11-253492 · Cited by 70 · see citing works

Current and future strategies to monitor and manage coagulation in ECMO patients

Shirejini, S. Z., Carberry, J., McQuilten, Z., Burrell, A. J. C., Gregory, S. D., & Hagemeyer, C. E. (2023) · Thrombosis Journal · doi:10.1186/s12959-023-00452-z · Cited by 70 · see citing works

How I treat warfarin-associated coagulopathy in patients with intracerebral hemorrhage

Goodnough, L. T., & Shander, A. (2011) · Blood · doi:10.1182/blood-2010-11-316075 · Cited by 67 · see citing works

Benefits and harms of 4-factor prothrombin complex concentrate for reversal of vitamin K antagonist associated bleeding: a systematic review and meta-analysis

Brekelmans, M. P. A., van Ginkel, K., Daams, J. G., Hutten, B. A., Middeldorp, S., & Coppens, M. (2017) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-017-1506-0 · Cited by 66 · see citing works

Pentadecapeptide BPC 157 reduces bleeding time and thrombocytopenia after amputation in rats treated with heparin, warfarin or aspirin

Stupnišek, M., Franjić, S., Drmić, D., Patrlj, M. H., Kolenc, D., Radić, B., Bojić, D., Včev, A., Seiwerth, S., & Sikirić, P. (2011) · Thrombosis Research · doi:10.1016/j.thromres.2011.07.035 · Cited by 63 · see citing works

What Is the Evidence for the Off-label Use of Recombinant Factor VIIa (rFVIIa) in the Acute Reversal of Warfarin?

Rosovsky, R. P. G., & Crowther, M. A. (2008) · Hematology · doi:10.1182/asheducation-2008.1.36 · Cited by 63 · see citing works

Factor IX complex for the correction of traumatic coagulopathy

Joseph, B. A., Amini, A., Friese, R. S., Houdek, M. T., Hays, D. P., Kulvatunyou, N., Wynne, J. L., O’Keeffe, T., Latifi, R., & Rhee, P. (2012) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e318247c944 · Cited by 62 · see citing works

Guías de actuación clínica en la hemorragia intracerebral

Rodríguez‐Yáñez, M., Castellanos, M., Freijo, M. D. M., Fernández, J. C. L., Martí‐Fábregas, J., Nombela, F., Simal, P., Castillo, J., Díez‐Tejedor, E., Fuentes, B., et al. (2011) · Neurología · doi:10.1016/j.nrl.2011.03.010 · Cited by 61 · see citing works

Emergency Neurological Life Support: Intracerebral Hemorrhage

Hemphill, J. C., & Lam, A. M. (2017) · Neurocritical Care · doi:10.1007/s12028-017-0453-0 · Cited by 57 · see citing works

The Practical Management of Intracerebral Hemorrhage Associated with Oral Anticoagulant Therapy

Masotti, L., Napoli, M. D., Godoy, D. A., Rafanelli, D., Liumbruno, G. M., Koumpouros, N., Landini, G., Pampana, A., Cappelli, R., Poli, D., et al. (2011) · International Journal of Stroke · doi:10.1111/j.1747-4949.2011.00595.x · Cited by 55 · see citing works

Warfarin and intracranial haemorrhage

Appelboam, R., & Thomas, E. (2008) · Blood Reviews · doi:10.1016/j.blre.2008.05.001 · Cited by 55 · see citing works

Warfarin Reversal in Anticoagulant-Associated Intracerebral Hemorrhage

Goldstein, J. N., Rosand, J. M., & Schwamm, L. H. (2008) · Neurocritical Care · doi:10.1007/s12028-008-9049-z · Cited by 53 · see citing works

Use and effectiveness of prothrombin complex concentrates vs fresh frozen plasma in gastrointestinal hemorrhage due to warfarin usage in the ED

Karaca, M. A., Erbil, B., & Özmen, M. M. (2014) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2014.02.016 · Cited by 53 · see citing works

Emergency Neurological Life Support: Intracerebral Hemorrhage

Andrews, C. M., Jauch, E. C., Hemphill, J. C., Smith, W. S., & Weingart, S. D. (2012) · Neurocritical Care · doi:10.1007/s12028-012-9757-2 · Cited by 51 · see citing works

Successful emergency reversal of phenprocoumon anticoagulation with prothrombin complex concentrate: a prospective clinical study

Lorenz, R. L., Kienast, J., Otto, U., Kiehl, M. G., Schreiter, D., Haertel, S., & Barthels, M. (2007) · Blood Coagulation & Fibrinolysis · doi:10.1097/mbc.0b013e3282010d7a · Cited by 48 · see citing works

Effectiveness of Factor IX Complex Concentrate in Reversing Warfarin Associated Coagulopathy for Intracerebral Hemorrhage

Siddiq, F., Jalil, A., McDaniel, C. M., Brock, D. G., Pineda, C. C., BELL, R. D., & Lee, K. (2007) · Neurocritical Care · doi:10.1007/s12028-007-9011-5 · Cited by 47 · see citing works

Treatments for reversing warfarin anticoagulation in patients with acute intracranial hemorrhage: a structured literature review

Bechtel, B. F., Nuñez, T. C., Lyon, J. A., Cotton, B. A., & Barrett, T. W. (2011) · International Journal of Emergency Medicine · doi:10.1186/1865-1380-4-40 · Cited by 46 · see citing works

Treatment of Acute Subdural Hematoma

Gerard, C. S., & Busl, K. M. (2013) · Current Treatment Options in Neurology · doi:10.1007/s11940-013-0275-0 · Cited by 45 · see citing works

An evidence-based warfarin management protocol reduces surgical delay in hip fracture patients

Ahmed, I., Khan, M., Nayak, V. K., & Mohsen, A. (2013) · Journal of Orthopaedics and Traumatology · doi:10.1007/s10195-013-0274-7 · Cited by 44 · see citing works

Massive, Fatal, Intracardiac Thrombosis Associated With Prothrombin Complex Concentrate

Warren, O. U., & Simon, B. (2009) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.12.027 · Cited by 43 · see citing works

Short‐term warfarin reversal for elective surgery – using low‐dose intravenous vitamin K: safe, reliable and convenient*

Burbury, K. L., Milner, A. D., Snooks, B., Jupe, D. M. L., & Westerman, D. (2011) · British Journal of Haematology · doi:10.1111/j.1365-2141.2011.08787.x · Cited by 42 · see citing works

Dabigatran bleed risk with closed head injuries: are we prepared?

Parra, M. W., Zucker, L., Johnson, E. S., Gullett, D., Avila, C., Wichner, Z. A., & Kokaram, C. R. (2013) · Journal of neurosurgery · doi:10.3171/2013.3.jns12503 · Cited by 42 · see citing works

A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents

Joppa, S., Salciccioli, J. D., Adamski, J., Patel, S. I., Wysokiński, W. E., McBane, R. D., Al‐Saffar, F., Esser, H., & Shamoun, F. E. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7020029 · Cited by 42 · see citing works

Prothrombin Complex Concentrate Accelerates International Normalized Ratio Reversal and Diminishes the Extension of Intracranial Hemorrhage in Geriatric Trauma Patients

Edavettal, M. M., Rogers, A. T., Rogers, F. B., Horst, M., & Leng, W. (2014) · The American Surgeon · doi:10.1177/000313481408000419 · Cited by 42 · see citing works

Small-molecule binding and sensing with a designed protein family

(2026) · doi:10.1038/s41467-026-70953-8 · Cited by 41 · see citing works

Appraisal of current vitamin K dosing algorithms for the reversal of over‐anticoagulation with warfarin: the need for a more tailored dosing regimen

Sconce, E. A., & Kamali, F. (2006) · European Journal Of Haematology · doi:10.1111/j.0902-4441.2006.t01-1-ejh2957.x · Cited by 41 · see citing works

Clinical practice guidelines in intracerebral haemorrhage

Rodríguez‐Yáñez, M., Castellanos, M., Freijo, M. M., Fernández, J. C. L., Martí‐Fábregas, J., Nombela, F., Simal, P., Castillo, J., Díez‐Tejedor, E., Fuentes, B., et al. (2013) · Neurología (English Edition) · doi:10.1016/j.nrleng.2011.03.011 · Cited by 40 · see citing works

Management dilemmas in patients with mechanical heart valves and warfarin-induced major bleeding

Panduranga, P. (2012) · World Journal of Cardiology · doi:10.4330/wjc.v4.i3.54 · Cited by 39 · see citing works

Benefits and Pitfalls of Point-of-Care Coagulation Testing for Anticoagulation Management

Wool, G. D. (2018) · American Journal of Clinical Pathology · doi:10.1093/ajcp/aqy087 · Cited by 38 · see citing works

Warfarin reversal emerging as the major indication for fresh frozen plasma use at a tertiary care hospital

Özgönenel, B., O’Malley, B. A., Krishen, P., & Eisenbrey, A. B. (2007) · American Journal of Hematology · doi:10.1002/ajh.20902 · Cited by 37 · see citing works

An audit of the role of vitamin K in the reversal of International Normalised Ratio (INR) in patients undergoing surgery for hip fracture

Bhatia, M., Talawadekar, G. D., Parihar, S., & Smith, A. J. (2010) · Annals of The Royal College of Surgeons of England · doi:10.1308/003588410x12664192075774 · Cited by 37 · see citing works

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo

Kienhuis, A. S., van de Poll, M. C. G., Dejong, C. H. C., Gottschalk, R. W. H., van Herwijnen, M. H. M., Boorsma, A., Kleinjans, J. C. S., Stierum, R. H., & van Delft, J. H. M. (2009) · Toxicology in Vitro · doi:10.1016/j.tiv.2009.06.005 · Cited by 36 · see citing works

Emergency reversal of anticoagulation: The real use of prothrombin complex concentrates

Desmettre, T., Dubart, A.-E., Capellier, G., Fanara, B., Puyraveau, M., Kepka, S., Coquart, J. B., Sheppard, F., & Tazarourte, K. (2012) · Thrombosis Research · doi:10.1016/j.thromres.2012.05.029 · Cited by 36 · see citing works

International Normalised Ratio Normalisation in Patients with Coumarin-Related Intracranial Haemorrhages – the INCH Trial: A Randomised Controlled Multicentre Trial to Compare Safety and Preliminary Efficacy of Fresh Frozen Plasma and Prothrombin Complex – Study Design and Protocol

Steiner, T., Freiberger, A., Griebe, M., Hüsing, J., Ivandic, B., Kollmar, R., Pfefferkorn, T., Wartenberg, K. E., Weimar, C., Hennerici, M. G., et al. (2011) · International Journal of Stroke · doi:10.1111/j.1747-4949.2010.00560.x · Cited by 36 · see citing works

Urgent reversal of vitamin K antagonist therapy

Vang, M. L., Hvas, A., & Ravn, H. B. (2011) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2011.02414.x · Cited by 36 · see citing works

A promising new alternative for the rapid reversal of warfarin coagulopathy in traumatic intracranial hemorrhage

Safaoui, M. N., Aazami, R., Hotz, H. A., Wilson, M. T., & Margulies, D. R. (2008) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2008.04.003 · Cited by 36 · see citing works

Point‐of‐care reversal treatment in phenprocoumon‐related intracerebral hemorrhage

Rizos, T., Jenetzky, E., Herweh, C., Hug, A., Hacke, W., Steiner, T., & Veltkamp, R. C. (2010) · Annals of Neurology · doi:10.1002/ana.21965 · Cited by 35 · see citing works

A French multicenter randomised trial comparing two dose-regimens of prothrombin complex concentrates in urgent anticoagulation reversal

Kerebel, D., Joly, L., Honnart, D., Schmidt, J., Damien Galanaud, E., Négrier, C., Kursten, F. W., Coriat, P., & Lex206 Investigator Group (2013) · Critical Care · doi:10.1186/cc11923 · Cited by 34 · see citing works

Warfarin-reversal: results of a phase III study with pasteurised, nanofiltrated prothrombin complex concentrate

Pabinger-Fasching, I. (2008) · Thrombosis Research · doi:10.1016/s0049-3848(08)70005-7 · Cited by 34 · see citing works

Anticoagulant Reversal in Gastrointestinal Bleeding: Review of Treatment Guidelines

Milling, T. J., Refaai, M. A., & Sengupta, N. (2021) · Digestive Diseases and Sciences · doi:10.1007/s10620-020-06728-y · Cited by 34 · see citing works

Efficacy of Warfarin Reversal in Orthopedic Trauma Surgery Patients

Tharmarajah, P., Pusey, J., Keeling, D. M., & Willett, K. M. (2007) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0b013e31802c4f3c · Cited by 34 · see citing works

The headache over warfarin in British neurosurgical intensive care units: a national survey of current practice

Appelboam, R., & Thomas, E. (2007) · Intensive Care Medicine · doi:10.1007/s00134-007-0765-1 · Cited by 34 · see citing works

Management of Warfarin Anticoagulation in Patients with Fractured Neck of Femur

Ashouri, F., Al-Jundi, W., Patel, A., & Mangwani, J. (2011) · ISRN Hematology · doi:10.5402/2011/294628 · Cited by 33 · see citing works

Reversal of Vitamin K Antagonist (VKA) effect in patients with severe bleeding: a French multicenter observational study (Optiplex) assessing the use of Prothrombin Complex Concentrate (PCC) in current clinical practice

Desmettre, T., Dehours, É., Samama, C. M., Jhundoo, S., Pujeau, F., Guillaudin, C.-H., Hecquart, C., Clerson, P., Crave, J. C., & Jaussaud, R. (2012) · Critical Care · doi:10.1186/cc11669 · Cited by 32 · see citing works

Modulation of neuroinflammation and oxidative stress by targeting GPR55 – new approaches in the treatment of psychiatric disorders

Apweiler, M., Saliba, S. W., Sun, L., Streyczek, J., Normann, C., Hellwig, S., Bräse, S., & Fiebich, B. L. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02614-5 · Cited by 30 · see citing works

Synthesis of conductive polymeric ionic liquid/Ni nanocomposite and its application to construct a nanostructure based electrochemical sensor for determination of warfarin in the presence of tramadol

Molaakbari, E., Mostafavi, A., Beitollahi, H., & Tohidiyan, Z. (2017) · Talanta · doi:10.1016/j.talanta.2017.04.041 · Cited by 30 · see citing works

Proximal femur fractures in patients taking anticoagulants

Papachristos, I. V., & Giannoudis, P. V. (2020) · EFORT Open Reviews · doi:10.1302/2058-5241.5.190071 · Cited by 28 · see citing works

Intracerebral haemorrhage: an often neglected medical emergency

Marietta, M., Pedrazzi, P., Girardis, M., & Torelli, G. (2007) · Internal and Emergency Medicine · doi:10.1007/s11739-007-0009-y · Cited by 28 · see citing works

Treatment and monitoring of coagulation abnormalities in children undergoing heart surgery

Arnold, P. D. (2010) · Pediatric Anesthesia · doi:10.1111/j.1460-9592.2010.03461.x · Cited by 27 · see citing works

Current State of Knowledge on Oral Anticoagulant Reversal Using Procoagulant Factors

Nitzki‐George, D., Wozniak, I., & Caprini, J. A. (2013) · Annals of Pharmacotherapy · doi:10.1345/aph.1r724 · Cited by 27 · see citing works

Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation

Blair, H. A., & Keating, G. M. (2017) · Drugs · doi:10.1007/s40265-017-0699-z · Cited by 27 · see citing works

Warfarin Therapy: Influence of Pharmacogenetic and Environmental Factors on the Anticoagulant Response to Warfarin

Siguret, V., Pautas, É., & Gouin‐Thibault, I. (2008) · Vitamins and hormones · doi:10.1016/s0083-6729(07)00012-x · Cited by 27 · see citing works

Experiences with an activated 4-factor prothrombin complex concentrate (FEIBA) for reversal of warfarin-related bleeding

Stewart, W. S., & Pettit, H. (2013) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2013.05.008 · Cited by 27 · see citing works

Investigating cell type specific mechanisms contributing to acute oral toxicity

Prieto, P. (2018) · ALTEX · doi:10.14573/altex.1805181 · Cited by 26 · see citing works

Pharmacologic Reversal of Warfarin-Associated Coagulopathy in Geriatric Patients With Hip Fractures

Vitale, M. A., VanBeek, C., Spivack, J., Cheng, B., & Geller, J. A. (2011) · Geriatric Orthopaedic Surgery & Rehabilitation · doi:10.1177/2151458511417434 · Cited by 26 · see citing works

Prothrombin complex concentrate for the urgent reversal of warfarin. Assessment of a standard dosing protocol

Wozniak, M., Kruit, A., Padmore, R., Giulivi, A., & Bormanis, J. (2012) · Transfusion and Apheresis Science · doi:10.1016/j.transci.2012.03.021 · Cited by 24 · see citing works

Managing Bleeding in Anticoagulated Patients in the Emergency Care Setting

Pollack, C. V. (2013) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2013.03.016 · Cited by 23 · see citing works

Management of Excessive Anticoagulant Effect Due to Vitamin K Antagonists

Dentali, F., & Crowther, M. A. (2008) · Hematology · doi:10.1182/asheducation-2008.1.266 · Cited by 23 · see citing works

Treating Warfarin-Related Intracerebral Hemorrhage

Hemphill, J. C. (2005) · Stroke · doi:10.1161/01.str.0000195152.46506.3e · Cited by 23 · see citing works

Prothrombin complex concentrate (Octaplex)

Carvalho, M. C., Rodrigues, A., Conceição, L. M., Galvão, M., & Ribeiro, L. C. (2012) · Blood Coagulation & Fibrinolysis · doi:10.1097/mbc.0b013e328351250f · Cited by 22 · see citing works

Comparison between Prothrombin Complex Concentrate (PCC) and Fresh Frozen Plasma (FFP) for the Urgent Reversal of Warfarin in Patients with Mechanical Heart Valves in a Tertiary Care Cardiac Center.

Farsad, B. F., Golpira, R., Najafi, H., Totonchi, Z., Salajegheh, S., Bakhshandeh, H., & Hashemian, F. (2015) · Europe PMC (PubMed Central) · Cited by 22 · see citing works

Hibernation and hemostasis

de Vrij, E. L., Bouma, H. R., Henning, R. H., & Cooper, S. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1207003 · Cited by 21 · see citing works

Anti-Coagulant and Anti-Thrombotic Properties of Blacklip Abalone (Haliotis rubra): In Vitro and Animal Studies

Suleria, H. A. R., Masci, P. P., Zhao, K., Addepalli, R., Chen, W., Osborne, S. A., & Gobe, G. C. (2017) · Marine Drugs · doi:10.3390/md15080240 · Cited by 21 · see citing works

Stroke Prevention in Atrial Fibrillation: A Clinical Perspective on Trials of the Novel Oral Anticoagulants

Morais, J., & Caterina, R. D. (2016) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-015-6632-3 · Cited by 20 · see citing works

Warfarin-induced bleeding complications — clinical presentation and therapeutic options

Wiedermann, C. J., & Stockner, I. (2008) · Thrombosis Research · doi:10.1016/s0049-3848(08)70004-5 · Cited by 74 · see citing works

Optimisation of the prothrombin complex concentrate dose for warfarin reversal

Makris, M. (2004) · Thrombosis Research · doi:10.1016/j.thromres.2004.10.005 · Cited by 37 · see citing works

Reversal of drug‐induced anticoagulation: old solutions and new problems

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