The DOI matches its Crossref record; 79 of the 79 references it cites were found in a registry or an index.
Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition
Open accessAbstract
The concept of antibody mediated CNS disorders is relatively recent. The classical CNS paraneoplastic neurological syndromes are thought to be T cell mediated, and the onconeural antibodies merely biomarkers for the presence of the tumour. Thus it was thought that antibodies rarely, if ever, cause CNS disease. Over the past 10 years, identification of autoimmune forms of encephalitis with antibodies against neuronal surface antigens, particularly the voltage gated potassium channel complex proteins or the glutamate N-methyl-D-aspartate receptor, have shown that CNS disorders, often without associated tumours, can be antibody mediated and benefit from immunomodulatory therapies. The clinical spectrum of these diseases is not yet fully explored, there may be others yet to be discovered and some types of more common disorders (eg, epilepsy or psychosis) may prove to have an autoimmune basis. Here, the known conditions associated with neuronal surface antibodies are briefly reviewed, some general aspects of these syndromes are considered and guidelines that could help in the recognition of further disorders are suggested.
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Cites
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Cited by
Inflammation in neurodegenerative diseases—An update
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Autoantibodies against neuronal progenitors in sera from children with autism
Mazur-Kolecka, B., Cohen, I. L., Gonzalez, M., Jenkins, E. C., Kaczmarski, W., Brown, W. T., Flory, M., & Frackowiak, J. (2014) · Brain and Development · doi:10.1016/j.braindev.2013.04.015 · Cited by 29
Metadata
- Authors
- Zuliani, L., Graus, F., Giometto, B., Bien, C., & Vincent, A.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 2012-03-24
- Volume
- 83
- Issue
- 6
- Pages
- 638-645
- ISSN
- 0022-3050 (ISSN-L)
- 1468-330X
- OpenAlex
- W2154980585
- Cited by
- 293
- References
- 79
- FWCI
- 25.24
- Type
- journal article
- Language
- en
- Open access
- hybrid
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