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Cited by 440

The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.

Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype

Open access
Mathey, Emily K, Park, Susanna B, Hughes, Richard A C, Pollard, John D, Armati, Patricia J, Barnett, Michael H, Taylor, Bruce V, Dyck, P James B, Kiernan, Matthew C, Lin, Cindy S-Y·2015·Journal of Neurology, Neurosurgery & Psychiatry

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an inflammatory neuropathy, classically characterised by a slowly progressive onset and symmetrical, sensorimotor involvement. However, there are many phenotypic variants, suggesting that CIDP may not be a discrete disease entity but rather a spectrum of related conditions. While the abiding theory of CIDP pathogenesis is that cell-mediated and humoral mechanisms act together in an aberrant immune response to cause damage to peripheral nerves, the relative contributions of T cell and autoantibody responses remain largely undefined. In animal models of spontaneous inflammatory neuropathy, T cell responses to defined myelin antigens are responsible. In other human inflammatory neuropathies, there is evidence of antibody responses to Schwann cell, compact myelin or nodal antigens. In this review, the roles of the cellular and humoral immune systems in the pathogenesis of CIDP will be discussed. In time, it is anticipated that delineation of clinical phenotypes and the underlying disease mechanisms might help guide diagnostic and individualised treatment strategies for CIDP.

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Metadata

Authors
Mathey, E. K., Park, S. B., Hughes, R. A. C., Pollard, J. D., Armati, P. J., Barnett, M. H., Taylor, B. V., Dyck, P. J. B., Kiernan, M. C., & Lin, C. S.-Y.
Venue
Journal of Neurology, Neurosurgery & Psychiatry
Publisher
BMJ
Published
2015-02-12
Volume
86
Issue
9
Pages
973-985
ISSN
  • 0022-3050 (ISSN-L)
  • 1468-330X
OpenAlex
W2110199093
Cited by
440
References
104
FWCI
25.51
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype. https://app.cochat.ai/papers/10.1136/jnnp-2014-309697
The paper
Mathey, E. K., Park, S. B., Hughes, R. A. C., Pollard, J. D., Armati, P. J., Barnett, M. H., Taylor, B. V., Dyck, P. J. B., Kiernan, M. C., & Lin, C. S.-Y. (2015). Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp-2014-309697

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.