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Cited by 341

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme

Open access
Ward, Nick S, Brander, Fran, Kelly, Kate·2019·Journal of Neurology, Neurosurgery & Psychiatry

Abstract

Objective: Persistent difficulty in using the upper limb remains a major contributor to physical disability post-stroke. There is a nihilistic view about what clinically relevant changes are possible after the early post-stroke phase. The Queen Square Upper Limb Neurorehabilitation programme delivers high-quality, high-dose, high-intensity upper limb neurorehabilitation during a 3-week (90 hours) programme. Here, we report clinical changes made by the chronic stroke patients treated on the programme, factors that might predict responsiveness to therapy and the relationship between changes in impairment and activity. Methods: Upper limb impairment and activity were assessed on admission, discharge, 6 weeks and 6 months after treatment, with modified upper limb Fugl-Meyer (FM-UL, max-54), Action Research Arm Test (ARAT, max-57) and Chedoke Arm and Hand Activity Inventory (CAHAI, max-91). Patient-reported outcome measures were recorded with the Arm Activity Measure (ArmA) parts A (0–32) and B (0–52), where lower scores are better. Results: 224 patients (median time post-stroke 18 months) completed the 6-month programme. Median scores on admission were as follows: FM-UL = 26 (IQR 16–37), ARAT=18 (IQR 7–33), CAHAI=40 (28-55), ArmA-A=8 (IQR 4.5–12) and ArmA-B=38 (IQR 24–46). The median scores 6 months after the programme were as follows: FM-UL=37 (IQR 24–48), ARAT=27 (IQR 12–45), CAHAI=52 (IQR 35–77), ArmA-A=3 (IQR 1–6.5) and ArmA-B=19 (IQR 8.5–32). We found no predictors of treatment response beyond admission scores. Conclusion: With intensive upper limb rehabilitation, chronic stroke patients can change by clinically important differences in measures of impairment and activity. Crucially, clinical gains continued during the 6-month follow-up period.

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Metadata

Authors
Ward, N. S., Brander, F., & Kelly, K.
Venue
Journal of Neurology, Neurosurgery & Psychiatry
Publisher
BMJ
Published
2019-02-15
Volume
90
Issue
5
Pages
498-506
ISSN
  • 0022-3050 (ISSN-L)
  • 1468-330X
OpenAlex
W2914392737
Cited by
341
References
32
FWCI
23.56
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme. https://app.cochat.ai/papers/10.1136/jnnp-2018-319954
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Ward, N. S., Brander, F., & Kelly, K. (2019). Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp-2018-319954

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