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Botulinum toxin in spasmodic torticollis.
Open accessAbstract
Ten patients with spasmodic torticollis were treated by injection of a total dose of 30 ng of botulinum toxin type A into the affected sternomastoid and posterior cervical muscles. Nine patients reported improvement in head position and control, which was confirmed in seven cases by clinical assessment and "blind" videotape ratings before and 6 weeks after injection. Five patients who had pain reported relief. Seven patients had mild transient dysphagia after injection; two who were given a more concentrated solution of the toxin developed more severe dysphagia, but this also recovered. Other minor transient side effects included weakness of the voice and local pain. The beneficial effects of botulinum toxin injections lasted some 2 to 3 months. A slight reduction in the total dose of toxin injected avoided the main side effects, and this method of treatment appears to offer successful control of head position and pain in the majority of patients with torticollis.
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Cited by
Treatment of spasticity with botulinum toxin: A double‐blind study
Snow, B. J., Tsui, J. K. C., Bhatt, M. H., Varelas, M., Hashimoto, S. A., & Calne, D. B. (1990) · Annals of Neurology · doi:10.1002/ana.410280407 · Cited by 414
Jankovic, J., Schwartz, K., & Donovan, D. T. (1990) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.53.8.633 · Cited by 353
Lackner, J. R., & DiZio, P. (1992) · The Head-Neck Sensory Motor System · doi:10.1093/acprof:oso/9780195068207.003.0033 · Cited by 11
Metadata
- Authors
- Stell, R., Thompson, P. D., & Marsden, C. D.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1988-07-01
- Volume
- 51
- Issue
- 7
- Pages
- 920-923
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2016765599
- Cited by
- 250
- References
- 0
- FWCI
- 11.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Botulinum toxin in spasmodic torticollis. https://app.cochat.ai/papers/10.1136/jnnp.51.7.920
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- Stell, R., Thompson, P. D., & Marsden, C. D. (1988). Botulinum toxin in spasmodic torticollis. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.51.7.920
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