The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasm.
Open accessAbstract
In the past five years, 477 patients with various focal dystonias and hemifacial spasm received 3,806 injections of botulinum A toxin for relief of involuntary spasms. A definite improvement with a global rating greater than or equal to 2 on a 0-4 scale, was obtained in all 13 patients with spasmodic dysphonia, 94% of 70 patients with blepharospasm, 92% of 13 patients with hemifacial spasm, 90% of 195 patients with cervical dystonia, 77% of 22 patients with hand dystonia, 73% of 45 patients with oromandibular dystonia, and in 90% of 21 patients with other focal dystonia who had adequate follow up. While the average duration of maximum improvement lasted about 11 weeks after an injection (range seven weeks in patients with hand dystonia to 15 weeks in patients with hemifacial spasm), some patients benefited for over a year. Only 16% of the 941 treatment visits with follow up were not successful. Except for transient focal weakness, there were very few complications or systemic effects attributed to the injections. This study supports the conclusion that botulinum toxin injections are a safe and effective therapy for patients with focal dystonia and hemifacial spasm.
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Citations
Cites
Botulinum A toxin for cranial‐cervical dystonia: A double‐blind, placebo‐controlled study
Jankovic, J., & Orman, J. (1987) · Neurology · doi:10.1212/wnl.37.4.616 · Cited by 553
Self-citationLocalized injections of botulinum toxin for the treatment of focal dystonia and hemifacial spasm
Brin, M. F., Fahn, S., Moskowitz, C., Friedman, A., Shale, H. M., Greene, P. E., Blitzer, A., List, T., Lange, D., Lovelace, R. E., et al. (1987) · Movement Disorders · doi:10.1002/mds.870020402 · Cited by 417
Blepharospasm and orofacial‐cervical dystonia: Clinical and pharmacological findings in 100 patients
Jankovic, J., & Ford, J. (1983) · Annals of Neurology · doi:10.1002/ana.410130406 · Cited by 318
Self-citationAcceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization
Dolly, J. O., Black, J., Williams, R. S., & Melling, J. (1984) · Nature · doi:10.1038/307457a0 · Cited by 314
Botulinum toxin in spasmodic torticollis.
Stell, R., Thompson, P. D., & Marsden, C. D. (1988) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.51.7.920 · Cited by 250
Effects of botulinum toxin injections on speech in adductor spasmodic dysphonia
Ludlow, C. L., Naunton, R. F., Sectary, S. E., Schulz, G. M., & Hallett, M. (1988) · Neurology · doi:10.1212/wnl.38.8.1220 · Cited by 209
Treatment of focal dystonias of the hand with botulinum toxin injections.
Cohen, L. G., Hallett, M., Geller, B. D., & Hochberg, F. (1989) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.3.355 · Cited by 174
Botulinum Toxin Injection of the Vocal Fold for Spasmodic Dysphonia: A Preliminary Report
Miller, R. H., Woodson, G. E., & Jankovic, J. J. (1987) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1987.01860060029009 · Cited by 131
Self-citationFocal task‐specific tremor and dystonia: Categorization of occupational movement disorders
Rosenbaum, F., & Jankovic, J. J. (1988) · Neurology · doi:10.1212/wnl.38.4.522 · Cited by 123
Self-citationBrin, M. F., Blitzer, A., Fahn, S., Lovelace, R. E., & Gould, W. J. (1989) · Movement Disorders · doi:10.1002/mds.870040401 · Cited by 88
Cited by
Botulinum toxin in the treatment of myofascial pain syndrome
Cheshire, W. P., Abashian, S. W., & Mann, D. J. (1994) · Pain · doi:10.1016/0304-3959(94)90048-5 · Cited by 340
Samotus, O., Rahimi, F., Lee, J., & Jog, M. (2016) · PLOS ONE · doi:10.1371/journal.pone.0153739 · Cited by 46
Do Bacteria Provide an Alternative to Cancer Treatment and What Role Does Lactic Acid Bacteria Play?
Dicks, L. M. T., & Vermeulen, W. (2022) · Microorganisms · doi:10.3390/microorganisms10091733 · Cited by 25
Metadata
- Authors
- Jankovic, J., Schwartz, K., & Donovan, D. T.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1990-08-01
- Volume
- 53
- Issue
- 8
- Pages
- 633-639
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2104616620
- Cited by
- 353
- References
- 10
- FWCI
- 6.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasm. https://app.cochat.ai/papers/10.1136/jnnp.53.8.633
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- Jankovic, J., Schwartz, K., & Donovan, D. T. (1990). Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasm. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.53.8.633
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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