Psychiatric symptoms in MELAS; a case report

Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome

Pavlakis, S. G., Phillips∥, P. C., DiMauro, S., Vivo, D. C. D., & Rowland, L. P. (1984) · Annals of Neurology · doi:10.1002/ana.410160409 · Cited by 1,188 · see citing works

MELAS: Clinical features, biochemistry, and molecular genetics

Ciafaloni, E., Ricci, E., Shanske, S., Moraes, C. T., Silvestri, G., Hirano, M., Simonetti, S., Angelini, C. I., Donati, M. A., Garcia, C., et al. (1992) · Annals of Neurology · doi:10.1002/ana.410310408 · Cited by 500 · see citing works

Topical Review: Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Strokelike Episodes (MELAS): Current Concepts

Hirano, M., & Pavlakis, S. G. (1994) · Journal of Child Neurology · doi:10.1177/088307389400900102 · Cited by 365 · see citing works

Epileptic Psychosis—Diagnostic Comparison with Process Schizophrenia

Perez, M., & Trimble, M. (1980) · The British Journal of Psychiatry · doi:10.1192/bjp.137.3.245 · Cited by 205 · see citing works

The expanding clinical spectrum of mitochondrial diseases

Vivo, D. C. D. (1993) · Brain and Development · doi:10.1016/0387-7604(93)90002-p · Cited by 162 · see citing works

Mitochondrial encephalomyopathy, lactic acidosis, stroke‐like episodes (MELAS): Clinical, radiological, pathological, and genetic observations

Koo, B. K. K., Becker, L. E., Chuang, S., Merante, F., Robinson, B. H., MacGregor, D., Tein, I., Ho, V. B., McGreal, D. A., Wherrett, J. R., et al. (1993) · Annals of Neurology · doi:10.1002/ana.410340107 · Cited by 117 · see citing works

Neuropsychiatric Manifestations of Right Hemisphere Lesions

Cummings, J. L. (1997) · Brain and Language · doi:10.1006/brln.1997.1832 · Cited by 81 · see citing works

Mitochondrial encephalomyopathy (MELAS) with mental disorder

Suzuki, T., Koizumi, J., Shiraishi, H., Ishikawa, N., Ofuku, K., Sasaki, M., Hori, T., Ohkoshi, N., & Anno, I. (1990) · Neuroradiology · doi:10.1007/bf00593949 · Cited by 60 · see citing works

Mitochondrial encephalomyopathy: variable clinical expression within a single kindred.

Crimmins, D. S., Morris, J. G., Walker, G. L., Sue, C. M., Byrne, E., Stevens, S., Jean-Francis, B., Yiannikas, C., & Pamphlett, R. (1993) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.56.8.900 · Cited by 52 · see citing works

Cerebrospinal fluid lactate and pyruvate concentrations in patients with Parkinson's disease and mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)

Yamamoto, M., Ujike, H., Wada, K., & Tsuji, T. (1997) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.62.3.290 · Cited by 20 · see citing works

[Follow-up studies and disorders of endocrinologic function in MELAS syndrome].

Robeck, S. L., Stefan, H., Engelhardt, A., & Neundörfer, B. (1996) · PubMed · Cited by 9 · see citing works

Cerebral White Matter

Schmahmann, J. D., Smith, E. E., Eichler, F., & Filley, C. M. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1444.017 · Cited by 492 · see citing works

Psychiatric Comorbidity in 36 Adults with Mitochondrial Cytopathies

Fattal, O., Link, J. N., Quinn, K. M., Cohen, B. H., & Franco, K. S. N. (2007) · CNS Spectrums · doi:10.1017/s1092852900015303 · Cited by 220 · see citing works

Review of the Literature on Major Mental Disorders in Adult Patients With Mitochondrial Diseases

Fattal, O., Budur, K., Vaughan, A. J., & Franco, K. (2006) · Psychosomatics · doi:10.1176/appi.psy.47.1.1 · Cited by 209 · see citing works

Mitochondrial DNA abnormalities and autistic spectrum disorders

Pons, R. M., Andreu, A. L., Checcarelli, N., Vilà, M. R., Engelstad, K., Sue, C. M., Shungu, D. C., Haggerty, R., Vivo, D. C. D., & DiMauro, S. (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2003.10.023 · Cited by 138 · see citing works

Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia

Munakata, K., Iwamoto, K., Bundo, M., & Kato, T. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.041 · Cited by 127 · see citing works

Mitochondrial DNA 3644T→C mutation associated with bipolar disorder

Munakata, K., Tanaka, M., Mori, K., Washizuka, S., Yoneda, M., Tajima, O., Akiyama, T., Nanko, S., Kunugi, H., Tadokoro, K., et al. (2004) · Genomics · doi:10.1016/j.ygeno.2004.08.015 · Cited by 113 · see citing works

Clinical mitochondrial genetics

Chinnery, P. F., Howell, N., Andrews, R. M., & Turnbull, D. M. (1999) · Journal of Medical Genetics · doi:10.1136/jmg.36.6.425 · Cited by 110 · see citing works

Cognitive impairment in neuromuscular disorders

D’Angelo, M. G., & Bresolin, N. (2006) · Muscle & Nerve · doi:10.1002/mus.20535 · Cited by 95 · see citing works

The role of mitochondrial dysfunction in psychiatric disease

Scaglia, F. (2010) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.115 · Cited by 96 · see citing works

Mitochondrial DNA (mtDNA) and schizophrenia

Vergé, B., Alonso, Y., Valero, J., Miralles, C., Vilella, E., & Martorell, L. (2010) · European Psychiatry · doi:10.1016/j.eurpsy.2010.08.008 · Cited by 91 · see citing works

The Psychiatric Presentation of Mitochondrial Disorders in Adults

Anglin, R. E., Tarnopolsky, M. A., Mazurek, M. F., & Rosebush, P. I. (2012) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/appi.neuropsych.11110345 · Cited by 77 · see citing works

The other, forgotten genome: mitochondrial DNA and mental disorders

Kato, T. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000926 · Cited by 72 · see citing works

The neuropsychiatry of adult-onset adrenoleukodystrophy

Rosebush, P. I., Garside, S., Levinson, A. J., & Mazurek, M. F. (1999) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.11.3.315 · Cited by 72 · see citing works

Mitochondrial Alterations and Neuropsychiatric Disorders

Marazziti, D., Baroni, S., Picchetti, M., Landi, P., Silvestri, S., Vatteroni, E., & Dell’Osso, M. C. (2011) · Current Medicinal Chemistry · doi:10.2174/092986711797379221 · Cited by 45 · see citing works

Mitochondrial DNA sequence analysis of patients with ‘atypical psychosis’

Kazuno, A., Munakata, K., Mori, K., Tanaka, M., Nanko, S., Kunugi, H., Umekage, T., Tochigi, M., Kohda, K., SASAKI, T., et al. (2005) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2005.01404.x · Cited by 31 · see citing works

Autosomal dominant psychiatric disorders and mitochondrial DNA multiple deletions: Report of a family

Mancuso, M., Ricci, G., Choub, A., Filosto, M., DiMauro, S., Davidzon, G., Tessa, A., Santorelli, F. M., Murri, L., & Siciliano, G. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.05.016 · Cited by 29 · see citing works

The Diagnosis of Psychosis

Cardinal, R. N., & Bullmore, E. T. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511686917 · Cited by 28 · see citing works

Congenital and Acquired Disorders Presenting as Psychosis in Children and Young Adults

Benjamin, S., Lauterbach, M. D., & Stanislawski-Zygaj, A. L. (2013) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2013.04.004 · Cited by 25 · see citing works

Mitochondrial DNA haplogroups and age at onset of schizophrenia

Magri, C., Gardella, R., Barlati, S. D., Valsecchi, P., Sacchetti, E., & Barlati, S. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30496 · Cited by 22 · see citing works

A Juvenile Case of MELAS with T3271C Mitochondrial DNA Mutation

Stenqvist, L., Paetau, A. E., Valanne, L. K., Suomalainen, A., & Pihko, H. S. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000169966.82325.1a · Cited by 20 · see citing works

Systematic Association Studies of Mitochondrial DNA Variations in Schizophrenia: Focus on the ND5 Gene

Bamne, M. N., Talkowski, M. E., Moraes, C. T., Manuck, S. B., Ferrell, R. E., Chowdari, K. V., & Nimgaonkar, V. L. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm100 · Cited by 19 · see citing works

The Differential Diagnosis of Childhood- and Young Adult-Onset Disorders That Include Psychosis

Lauterbach, M. D., Stanislawski-Zygaj, A. L., & Benjamin, S. (2008) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.20.4.409 · Cited by 19 · see citing works

A5814G Mutation in Mitochondrial DNA Can Cause Mitochondrial Myopathy and Cardiomyopathy

Karadimas, C. L., Tanji, K., Geremek, M., Chronopoulou, P., Vu, T., Krishna, S., Sue, C. M., Shanske, S., Bonilla, E., DiMauro, S., et al. (2001) · Journal of Child Neurology · doi:10.1177/088307380101600715 · Cited by 18 · see citing works

Stroke-like episodes in adult mitochondrial disease

Ng, Y. S., & Gorman, G. S. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-12-821751-1.00005-1 · Cited by 12 · see citing works

Persistent organic personality change as rare psychiatric manifestation of MELAS syndrome

K�ller, H., Kornischka, J., Neuen-Jacob, E., Saleh, A., von Giesen, H.-J., Schmiedel, J., Reichmann, H., & Hartung, H. (2003) · Journal of Neurology · doi:10.1007/s00415-003-0260-8 · Cited by 12 · see citing works

Cognitive functioning and psychiatric disorders in children with a metabolic disease

Simons, A., Eyskens, F. J. M., Groof, A. D., Diest, E. V., Deboutte, D., & Vermeiren, R. R. J. M. (2006) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-006-0524-9 · Cited by 11 · see citing works

Pilot Study on Executive Function and Adaptive Skills in Adolescents and Young Adults With Mitochondrial Disease

Schreiber, H. (2012) · Journal of Child Neurology · doi:10.1177/0883073812442589 · Cited by 10 · see citing works

The Mitochondrial DNA A3243A>G Mutation Must Be An Infrequent Cause Of Asperger Syndrome

Kent, L., Lambert, C., Pyle, A., Elliott, H. R., Wheelwright, S. J., Baron‐Cohen, S., & Chinnery, P. F. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2005.08.060 · Cited by 9 · see citing works

Chapter 2 Clinical Features of the Mitochondrial Encephalomyopathies

Hart, P. E., Vivo, D. C. D., & Schapira, A. H. V. (2002) · Blue books of practical neurology · doi:10.1016/s1877-3419(09)70061-3 · Cited by 8 · see citing works

Psychiatric care for a person with MELAS syndrome: A case report

Leong, D. Y., Chee, R. Y., & Lui, Y. S. (2021) · Clinical Case Reports · doi:10.1002/ccr3.4146 · Cited by 3 · see citing works

Mitochondrial Myopathy Complicated by Eating Disorder: A Case Report Highlighting the Potential Interaction of Genetic, Metabolic, and Psychodynamic Factors

Deutsch, S. I., Rosse, R. B., Yaseen, M., Schulman, H. M., & Abraham, S. (2007) · CNS Spectrums · doi:10.1017/s1092852900021040 · Cited by 3 · see citing works

Psychiatric manifestations in a patient with a pathogenic variant in the MT-TL1 gene associated with MELAS

Gujrati, A., Datar, M. C., Makhija, A. M., & Shetty, J. V. (2025) · BMJ Case Reports · doi:10.1136/bcr-2024-264055 · Cited by 2 · see citing works

The Neurovascular Neuropsychology of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS)

Benisty, S., & Chabriat, H. (2020) · Springer eBooks · doi:10.1007/978-3-030-49586-2_7 · Cited by 2 · see citing works

Integratie van opleiding en onderzoek in de opleiding tot psychiater

Verhoeven, W. M. A., Goessens, L. F. M., van den Berg, Y. W. M. M., & Tuinier, S. (1999) · Acta Neuropsychiatrica · doi:10.1017/s0924270800036310 · Cited by 2 · see citing works

Psychiatric aspects of the MELAS syndrome

Lačković, M. (2023) · Galenika Medical Journal · doi:10.5937/galmed2307062l · Cited by 1 · see citing works

Mitochondrial disorders and psychosis

Velakoulis, D., & Walterfang, M. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511789977.018 · Cited by 1 · see citing works

Diagnosis in psychiatry; a piece of cake?

Verhoeven, W. M. A., der Heijden, F. M. M. A. V., Tuinier, S., & Egger, J. J. M. (2001) · Acta Neuropsychiatrica · doi:10.1017/s0924270800040072 · Cited by 1 · see citing works

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-like Episodes (MELAS)

Benisty, S., & Chabriat, H. (2009) · Springer eBooks · doi:10.1007/978-0-387-70715-0_8

Utilización de haloperidol en un paciente con síndrome de encefalomiopatía mitocondrial, acidosis láctica y episodios parecidos a ictus (síndrome MELAS)

Acebrón, F., Martín, C. A., Barroeta, A. D. A.-C., Rubio, C., Torre, P. P., Luengo, A. V., Corral, Í., Cánovas, A. A., & Rodríguez, J. O. (2015) · Psiquiatría Biológica · doi:10.1016/j.psiq.2015.10.006

Alterazioni mitocondriali e patologie psichiatriche Mitochondrial dysfunctions and psychiatric disorders

Marazziti, D., Baroni, S., Picchetti, M., & Silvestri, S. (2009)

Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome

Pavlakis, S. G., Phillips∥, P. C., DiMauro, S., Vivo, D. C. D., & Rowland, L. P. (1984) · Annals of Neurology · doi:10.1002/ana.410160409 · Cited by 1,188 · see citing works

MELAS reflects a clinical concept with heterogeneous genetic background

Finsterer, J., & Zarrouk‐Mahjoub, S. (2019) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x20190003

MELAS (Myopathy, Encephalopathy, Lactic Acidosis, Stroke-like Episodes)

Angelini, C. I. (2014) · Springer eBooks · doi:10.1007/978-3-319-07500-6_53 · Cited by 1 · see citing works

Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS)

Goldstein, A. C., & Servidei, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-05517-2_5 · Cited by 14 · see citing works

Mitochondrial encephalomyopathy, lactic acidosis, stroke‐like episodes (MELAS): Clinical, radiological, pathological, and genetic observations

Koo, B. K. K., Becker, L. E., Chuang, S., Merante, F., Robinson, B. H., MacGregor, D., Tein, I., Ho, V. B., McGreal, D. A., Wherrett, J. R., et al. (1993) · Annals of Neurology · doi:10.1002/ana.410340107 · Cited by 117 · see citing works