The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Evaluation of abnormal liver function tests
Abstract
Incidentally detected abnormality in liver function tests is a common situation encountered by physicians across all disciplines. Many of these patients do not have primary liver disease as most of the commonly performed markers are not specific for the liver and are affected by myriad factors unrelated to liver disease. Also, many of these tests like liver enzyme levels do not measure the function of the liver, but are markers of liver injury, which is broadly of two types: hepatocellular and cholestatic. A combination of a careful history and clinical examination along with interpretation of pattern of liver test abnormalities can often identify type and aetiology of liver disease, allowing for a targeted investigation approach. Severity of liver injury is best assessed by composite scores like the Model for End Stage Liver Disease rather than any single parameter. In this review, we discuss the interpretation of the routinely performed liver tests along with the indications and utility of quantitative tests.
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Cited by
Cheng, A.-L., Guan, Z., Chen, Z., Tsao, C.-J., Qin, S., Kim, J. S., Yang, T.-S., Tak, W. Y., Pan, H., Yu, S., et al. (2012) · European Journal of Cancer · doi:10.1016/j.ejca.2011.12.006 · Cited by 259
Pestana, J. M., Puerta, B., Santos, H., Madeira, M. S., Alfaia, C. M., Lopes, P. A., Pinto, R. M. A., Lemos, J. P. C., Fontes, C. M. G. A., Lordelo, M. M., et al. (2020) · Poultry Science · doi:10.1016/j.psj.2019.11.069 · Cited by 119
Role of Carnitine in Non-alcoholic Fatty Liver Disease and Other Related Diseases: An Update
Li, N., & Zhao, H. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.689042 · Cited by 79
Moradi Kelardeh, B., Rahmati-Ahmadabad, S., Farzanegi, P., Helalizadeh, M., & Azarbayjani, M.-A. (2020) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2020.02.021 · Cited by 67
Reddy, M., Fenn, S., Rolnik, D. L., Mol, B. W., da Silva Costa, F., Wallace, E. M., & Palmer, K. R. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.08.019 · Cited by 61
Metadata
- Authors
- Agrawal, S., Dhiman, R. K., & Limdi, J. K.
- Venue
- Postgraduate Medical Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-02-03
- Volume
- 92
- Issue
- 1086
- Pages
- 223-234
- ISSN
- 0032-5473 (ISSN-L)
- 1469-0756
- OpenAlex
- W2119439822
- Cited by
- 454
- References
- 49
- FWCI
- 30.53
- Type
- journal article
- Language
- en
- Open access
- closed
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