The DOI matches its OpenAlex record; 32 of the 32 references it cites were found in a registry or an index.
RING fingers and B-boxes: zinc-binding protein-protein interaction domains
Abstract
The cysteine-rich zinc-binding motifs known as the RING and B-box are found in several unrelated proteins. Structural, biochemical, and biological studies of these motifs reveal that they mediate protein-protein interactions. Several RING-containing proteins are oncoproteins and recent data indicate that proapoptotic activities can be mediated through the RING. 1H NMR methods were used to determine the structures of RINGs and a B-box domain and to monitor the conformational changes these motifs undergo upon zinc ligation. This review discusses in detail the structural features of the RING and B-box domains. Further, possible structure function relationships for these motifs particularly in their role as protein interaction domains are discussed.
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Cites
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The PHD finger: Implications for chromatin-mediated transcriptional regulation
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The RING finger domain: a recent example of a sequence—structure family
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Self-citationCharacterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia
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Cited by
The tripartite motif family identifies cell compartments
Reymond, A., Meroni, G., Fantozzi, A., Merla, G., Cairo, S., Luzi, L., Riganelli, D., Zanaria, E., Messali, S., Cainarca, S., et al. (2001) · The EMBO Journal · doi:10.1093/emboj/20.9.2140 · Cited by 1,366
The Evolution of CONSTANS-Like Gene Families in Barley, Rice, and Arabidopsis
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A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.
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Minucci, S., Nervi, C., Coco, F. L., & Pelicci, P. G. (2001) · Oncogene · doi:10.1038/sj.onc.1204336 · Cited by 163
Metadata
- Authors
- Borden, K. L. B.
- Venue
- Biochemistry and Cell Biology
- Publisher
- NRC Research Press
- Published
- 1998-01-01
- Volume
- 76
- Issue
- 2-3
- Pages
- 351-358
- ISSN
- 0829-8211 (ISSN-L)
- OpenAlex
- W2017817760
- Cited by
- 261
- References
- 32
- FWCI
- 3.38
- Type
- journal article
- Language
- en
- Open access
- closed
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- Borden, K. L. B. (1998). RING fingers and B-boxes: zinc-binding protein-protein interaction domains. Biochemistry and Cell Biology. https://doi.org/10.1139/bcb-76-2-3-351
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
