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Cited by 7Nausea and vomiting managementVestibular and auditory disordersPoisoning and overdose treatments

THE EFFECT OF BARBITURATES AND OTHER SUBSTANCES ON MOTION SICKNESS IN DOGS

Noble, R. L.·1948·Canadian Journal of Research
DOI 10.1139/cjr48e-016
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Abstract

A large series of barbiturates and other substances have been tested for their ability to prevent motion sickness in dogs. Many compounds were found to possess this activity, which was not related to the anesthetic property of the compound. A number of barbiturates were found to be considerably more active than V-12, which was used as a standard. Pyridoxine, hyoscine, and streptomycin were inactive in the tests described. Bulbocapnine possessed half the potency of V-12 and showed an additive effect when the two substances were given together.

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Crossref · 10.1139/cjr48e-016

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  • Neuroleptics including barbiturates, diazepam, baclofen, and phenytoin are effective in prevention of motion sickness.

    “Neuroleptics including barbiturates, diazepam, and baclofen as well as phenytoin were found to be effective in prevention of MS [114-118] (Table 2).”

    From Motion Sickness: Current Knowledge and Recent Advance. (2016) · cites this paper as [114]

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Authors
Noble, R. L.
Corresponding author
Noble, R. L.
Venue
Canadian Journal of Research
Publisher
Canadian Science Publishing
Published
1948-10-01
Volume
26e
Issue
5
Pages
283-294
ISSN
  • 0366-6581 (ISSN-L)
  • 1923-4287
DOI
10.1139/cjr48e-016
OpenAlex
W1965562599
Cited by
7
References
0
Citations by year
2015: 1
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Licence
www.nrcresearchpress.com/page/about/CorporateTextAndDataMining (tdm)
Locations
  • Canadian Journal of Research/Canadian journal of research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Nausea and vomiting management
  • Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
  • Health Sciences › Medicine › Emergency Medicine › Poisoning and overdose treatments
Keywords
barbiturates, motion sickness, antiemetic activity, vitamin B12, bulbocapnine, pyridoxine, scopolamine, streptomycin, dogs, additive drug effects
MeSH terms
Animals, Barbiturates, Dogs, Motion Sickness

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