Cited by 54,751Lipid metabolism and biosynthesisEdible Oils Quality and AnalysisFood Nutrient Composition and Product Development

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., Dyer, W. J.·1959·Canadian Journal of Biochemistry and Physiology

DOI 10.1139/o59-099

Open this paper in CoChat — free account

Abstract

Lipid decomposition studies in frozen fish have led to the development of a simple and rapid method for the extraction and purification of lipids from biological materials. The entire procedure can be carried out in approximately 10 minutes; it is efficient, reproducible, and free from deleterious manipulations. The wet tissue is homogenized with a mixture of chloroform and methanol in such proportions that a miscible system is formed with the water in the tissue. Dilution with chloroform and water separates the homogenate into two layers, the chloroform layer containing all the lipids and the methanolic layer containing all the non-lipids. A purified lipid extract is obtained merely by isolating the chloroform layer. The method has been applied to fish muscle and may easily be adapted to use with other tissues.

Integrity signals

Registry

Crossref · 10.1139/o59-099

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189
PREPARATION OF LIPIDE EXTRACTS FROM BRAIN TISSUE
Folch, J., Ascoli, I., Lees, M. B., Meath, J. A., & Lebaron, F. N. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55987-1 · Cited by 1,341
Storage of Frozen Plaice Fillets
Dyer, W. J., & Morton, M. L. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-007 · Cited by 69
Self-citation
Experimental Determination of Binodal Curves, Plait Points, and Tie Lines, in 50 Systems, each consisting of Water and Two Organic Liquids
Bonner, W. D. (1910) · The Journal of Physical Chemistry · doi:10.1021/j150116a004 · Cited by 46
Acetone–Water Mixtures for the Extraction and Rapid Estimation of Fats of Biological Materials, Particularly Fish Products
Dambergs, N. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-045 · Cited by 18

Show all 5 references

Research works printed but not linked: 1

BANCROFT W., 1895, Phys. Iiev., 3, 1

Sorted by citations

Items 14,101–14,200 of 48,846

Dibutyryl cyclic AMP decreases proliferative activity and the cholesteryl ester content in cultured cells of atherosclerotic human aorta
Tertov, V. V., Orekhov, A. N., Repin, V. S., et al. (1982) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(82)91908-8 · Cited by 46
Lipolysis and Lipid Oxidation in Frozen Minced Mackerel as Related to Tg', Molecular Diffusion, and Presence of Gelatin
Brake, N., & Fennema, O. R. (1999) · Journal of Food Science · doi:10.1111/j.1365-2621.1999.tb09854.x · Cited by 46
Interaction with Membrane Lipids and Heme Ligand Binding Properties of Escherichia coli Flavohemoglobin
Bonamore, A., Farina, A., Gattoni, M., et al. (2003) · Biochemistry · doi:10.1021/bi0206311 · Cited by 46
Pseudomonas aeruginosa Degrades Pulmonary Surfactant and Increases Conversion In Vitro
Beatty, A. L., Malloy, J. L., & Wright, J. R. (2004) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2004-0276oc · Cited by 46
Interaction of sphingomyelinase with sphingomyelin analogs modified at the C-1 and C-3 positions of the sphingosine backbone
Lister, M. D., Ruan, Z.-S., & Bittman, R. (1995) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(94)00249-x · Cited by 46
Infrared and 31P-NMR studies of the interaction of Mg2+ with phosphatidylserines: effect of hydrocarbon chain unsaturation
Casal, H. L., Mantsch, H. H., & Häuser, H. (1989) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(89)90059-x · Cited by 46
Enhancement of interferon-β production with sphingomyelin from fermented milk
Osada, K., Nagira, K., Teruya, K., Tachibana, H., Shirahata, S., & Murakami, H. (1993) · Biotherapy · doi:10.1007/bf01877735 · Cited by 46
Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes*
Kühn, H., Belkner, J., & Wiesner, R. (1990) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1990.tb19113.x · Cited by 46
Characterization of Shrimp Lipids
Johnston, J. J., GHANBARI, H. A., Wheeler, W. B., et al. (1983) · Journal of Food Science · doi:10.1111/j.1365-2621.1983.tb14782.x · Cited by 46
Hydrostatic Pressure Induces the Fusion-active State of Enveloped Viruses
Gaspar, L. P., Silva, A. C. B., Gomes, A. M. O., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106096200 · Cited by 46
PDMP Blocks Brefeldin A–induced Retrograde Membrane Transport from Golgi to ER: Evidence for Involvement of Calcium Homeostasis and Dissociation from Sphingolipid Metabolism
Kok, J., Babià, T., Filipeanu, C. M., Nelemans, A., Egea, G., & Hoekstra, D. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.1.25 · Cited by 47
A glycoprotein in the accessory cell of the echinoid ovary and its role in vitellogenesis
Ozaki, H., Moriya, O., & Harrington, F. E. (1986) · Development Genes and Evolution · doi:10.1007/bf00444043 · Cited by 46
Distribution of Carbon and Nitrogen Isotope Ratios in the Yodo River Watershed
Yamada, Y., Ueda, T., & Wada, E. (1996) · Japanese Journal of Limnology (Rikusuigaku Zasshi) · doi:10.3739/rikusui.57.467 · Cited by 46
Routine high‐performance liquid chromatographic determination of free 7‐ketocholesterol in some foods by two different analytical methods
Penzzi, G., Caboni, M. F., Zunin, P., et al. (1995) · Journal of the American Oil Chemists Society · doi:10.1007/bf02577847 · Cited by 46
MORPHOLOGY AND CHEMICAL COMPOSITION OF A NATURAL POPULATION OF AN ICE‐ASSOCIATED ANTARCTIC DIATOM NAVICULA GLACIEI1
Whitaker, T. M., & Richardson, M. G. (1980) · Journal of Phycology · doi:10.1111/j.1529-8817.1980.tb03027.x · Cited by 46
Lipid oxidation in meats of omega-3 fatty acid-enriched broiler chickens
O’Keefe, S. F., PROUDFOOT, F. G., & ACKMAN, R. G. (1995) · Food Research International · doi:10.1016/0963-9969(95)00021-d · Cited by 46
Properties of a mini 9R-lipoxygenase from Nostoc sp. PCC 7120 and its mutant forms
Andreou, A. Z., Vanko, M., Bezáková, L., et al. (2008) · Phytochemistry · doi:10.1016/j.phytochem.2008.03.002 · Cited by 46
Proper axonal distribution of PrPC depends on cholesterol–sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons
Galván, C. A., Camoletto, P. G., Dotti, C. G., et al. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.07.003 · Cited by 46
Isolation and characterization of a reservosome fraction from Trypanosoma cruzi
Cunha‐e‐Silva, N. L., Atella, G. C., Porto-Carreiro, I., Morgado‐Díaz, J. A., Pereira, M. G., & de Souza, W. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11317.x · Cited by 47
Identification, isolation and characterization of tetracosapolyenoic acids in lipids of marine coelenterates
Vyssotski, M. V., & Svetashev, V. I. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90037-i · Cited by 46
Gallbladder emptying in vivo, bile composition, and nucleation of cholesterol crystals in patients with cholesterol gallstones
Stolk, M. F. J., van Erpecum, K. J., Renooij, W., et al. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90153-1 · Cited by 46
Isolation of a cDNA Encoding Human Lysophosphatidic Acid Phosphatase That Is Involved in the Regulation of Mitochondrial Lipid Biosynthesis
Hiroyama, M., & Takenawa, T. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.41.29172 · Cited by 46
Intraspecific differences in the biochemical composition of a diatom during a spring bloom in Villefranche-sur-Mer Bay, Mediterranean Sea
Claustre, H., Marty, J., & Cassiani, L. (1989) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/0022-0981(89)90060-9 · Cited by 46
Hypoxic control of the development of the surfactant system in the chicken: evidence for physiological heterokairy
Blacker, H. A., Orgeig, S., & Daniels, C. B. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00399.2003 · Cited by 46
Surfactant Protein A Modulates the Inflammatory Response in Macrophages during Tuberculosis
Gold, J. A., Hoshino, Y., Tanaka, N., et al. (2004) · Infection and Immunity · doi:10.1128/iai.72.2.645-650.2004 · Cited by 46
A re-examination of the fate of glyceride-glycerol in neutral lipid absorption and transport
Mansbach, C. M., & Parthasarathy, S. (1982) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38073-1 · Cited by 46
Occurrence of 5c,8c,11c,15t‐eicosatetraenoic acid and other unusual polyunsaturated fatty acids in rats fed partially hydrogenated calola oil
Ratnayake, W. M. N., Chen, Z., Pelletier, G., & Weber, D. F. (1994) · Lipids · doi:10.1007/bf02538915 · Cited by 46
THE ASSIMILATION OF PROTEIN AND CARBOHYDRATE FROM PREPARED DIETS BY THE SHRIMP,Penaeus stylirostris
Fenucci, J. L., de Fenucci, A. C., Lawrence, A. L., et al. (1982) · Journal of the World Mariculture Society · doi:10.1111/j.1749-7345.1982.tb00020.x · Cited by 46
Phorbol ester-induced priming of superoxide generation by phosphatidic acid-stimulated neutrophils and granule-free neutrophil cytoplasts
Siddiqui, R. A., English, D. K., Harvey, K. A., et al. (1995) · Journal of Leukocyte Biology · doi:10.1002/jlb.58.2.189 · Cited by 46
Essential fatty acid deficiency in mice is associated with hepatic steatosis and secretion of large VLDL particles
Werner, A., Havinga, R., Bos, T., Bloks, V. W., Kuipers, F., & Verkade, H. J. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00456.2004 · Cited by 47
Two Distinct Phospholipases C of Listeria monocytogenes Induce Ceramide Generation, Nuclear Factor-κB Activation, and E-Selectin Expression in Human Endothelial Cells
Schwarzer, N., Nöst, R., Seybold, J., Parida, S. K., Fuhrmann, O., Krüll, M., Schmidt, R., Newton, R. C., Hippenstiel, S., Domann, E., et al. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.6.3010 · Cited by 50
Specificity of the glycolipid transfer protein from pig brain.
Yamada, K. M., Abe, A., & Sasaki, T. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89115-3 · Cited by 46
Physiological Studies on the Recovery of Salt Tolerance by Staphylococcus aureus After Sublethal Heating
Hurst, A., Hughes, A., Beare‐Rogers, J. L., et al. (1973) · Journal of Bacteriology · doi:10.1128/jb.116.2.901-907.1973 · Cited by 46
Archaea contain a novel diether phosphoglycolipid with a polar head group identical to the conserved core of eucaryal glycosyl phosphatidylinositol.
Nishihara, M., Utagawa, M., Akutsu, H., & Koga, Y. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42294-6 · Cited by 45
Alteration of the binding specificity of cellular retinol-binding protein II by site-directed mutagenesis.
Cheng, L., Qian, S. J., Rothschild, C., d'Avignon, A., Lefkowith, J. B., Gordon, J. I., & Li, E. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54243-5 · Cited by 45
Comparison of three species of fish consumed as part of a Western diet: effects on platelet fatty acids and function, hemostasis, and production of thromboxane
Wander, R. C., & Patton, B. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.2.326 · Cited by 46
Docosahexaenoic Acid and Vitamin E Can Reduce Human Monocytic U937 Cell Apoptosis Induced by Tumor Necrosis Factor
Yano, M., Kishida, E., Iwasaki, M., Kojo, S., & Masuzawa, Y. (2000) · Journal of Nutrition · doi:10.1093/jn/130.5.1095 · Cited by 46
Heat sterilization of archaeal liposomes
Choquet, C. G., Patel, G. B., & Sprott, G. D. (1996) · Canadian Journal of Microbiology · doi:10.1139/m96-027 · Cited by 46
Reconstituted human erythrocyte sugar transporter activity is determined by bilayer lipid groups
Tefft, R. E., Carruthers, A., & Melchior, D. L. (1986) · Biochemistry · doi:10.1021/bi00360a035 · Cited by 46
Exogenous Surfactant Preserves Lung Function and Reduces Alveolar Evans Blue Dye Influx in a Rat Model of Ventilation-induced Lung Injury
Verbrugge, S. J. C., de Anda, G. V., Gommers, D. A. M. P. J., et al. (1998) · Anesthesiology · doi:10.1097/00000542-199808000-00024 · Cited by 46
Stimulation of cholinephosphate cytidylyltransferase activity by estrogen in fetal rabbit lung is mediated by phospholipids
Chu, A. J., & Rooney, S. A. (1985) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(85)90008-6 · Cited by 46
Hypoxia increases stimulus-induced PAF production and release from human umbilical vein endothelial cells
Caplan, M. S., Adler, L., Kelly, A. M., et al. (1992) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(92)90309-j · Cited by 46
Low-frequency motion in membranes. The effect of cholesterol and proteins
Cornell, B. A., Davenport, J. B., & Separovic, F. (1982) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(82)90267-x · Cited by 46
Age-related alterations in cultured human fibroblast membrane structure and function
Schroeder, F., Goetz, I. E., & Roberts, E. (1984) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(84)90010-1 · Cited by 46
Interactions of the Nicotinic Acetylcholine Receptor Transmembrane Segments with the Lipid Bilayer in Native Receptor-Rich Membranes
Dreger, M., Krauss, M., Herrmann, A., et al. (1997) · Biochemistry · doi:10.1021/bi960666z · Cited by 46
sn-1,2-Diacylglycerol Levels in the FungusNeurospora crassa Display Circadian Rhythmicity
Ramsdale, M., & Lakin‐Thomas, P. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002911200 · Cited by 46
Soy Protein Isolate Solubility and Surface Hydrophobicity as affected by Antioxidants
Boatright, W. L., & HElTlARACHCHY, N. S. (1995) · Journal of Food Science · doi:10.1111/j.1365-2621.1995.tb06232.x · Cited by 46
Effect of Two Types of Fish Oil Supplementation on Plasma and Erythrocyte Phospholipids in Formula-Fed Term Infants
Maurage, C., Guesnet, P., Pinault, M., et al. (1998) · Neonatology · doi:10.1159/000014063 · Cited by 46
Phospholipase D-derived Products in the Regulation of 12- -Tetradecanoylphorbol-13-acetate-stimulated Prostaglandin Synthesis in Madin-Darby Canine Kidney Cells
Sciorra, V. A., & Daniel, L. W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.24.14226 · Cited by 46
Does an Increase in Membrane Unsaturated Fatty Acids Account for Tween 80 Stimulation of Glucosyltransferase Secretion by Streptococcus salivarius?
Jacques, N. A., Jacques, V. L., WOLF, A. C., et al. (1985) · Microbiology · doi:10.1099/00221287-131-1-67 · Cited by 46
Polycyclic Aromatic Hydrocarbons in Freshwater Isopods and Field-Partitioning Between Abiotic Phases
van Hattum, B., Pons, M. J. C., & Montañés, J. F. C. (1998) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s002449900374 · Cited by 46
Palmitoylation of lung surfactant protein SP-C alters surface thermodynamics, but not protein secondary structure or orientation in 1,2-dipalmitoylphosphatidylcholine Langmuir films
Flach, C. R., Gericke, A., Keough, K. M. W., et al. (1999) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(98)00205-3 · Cited by 46
Non‐electrolyte solute permeabilities of human placental microvillous and basal membranes.
Jansson, T., Powell, T. L., & Illsley, N. P. (1993) · The Journal of Physiology · doi:10.1113/jphysiol.1993.sp019770 · Cited by 46
Effect of pH on solubility and ionic state of lipopolysaccharide obtained from the deep rough mutant of Escherichia coli
Din, Z. Z., Mukerjee, P., KASTOWSKY, M., et al. (1993) · Biochemistry · doi:10.1021/bi00068a014 · Cited by 46
Abnormal vitamin D metabolism in cirrhosis.
Jung, R. T., Davie, M. W. J., Hunter, J. O., et al. (1978) · Gut · doi:10.1136/gut.19.4.290 · Cited by 46
Sequential actions of glucose oxidase and peroxidase in molecular films assembled by layer-by-layer alternate adsorption
Onda, M., LVOV, Y. M., Ariga, K., & Kunitake, T. (1996) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19960720)51:2 · Cited by 262
Differential accumulation of diacyl and plasmalogenic diglycerides during myocardial ischemia.
Ford, D. A., & Gross, R. W. (1989) · Circulation Research · doi:10.1161/01.res.64.1.173 · Cited by 46
Isotopic and biochemical composition of particulate organic matter in a shallow water estuary (Great Ouse, North Sea, England)
Fichez, R., Dennis, P. F., Fontaine, M. F., et al. (1993) · Marine Chemistry · doi:10.1016/0304-4203(93)90231-c · Cited by 46
The alkane oxidation system of Pseudomonas oleovorans: induction of the alk genes in Escherichia coli W3110(pGEc47) affects membrane biogenesis and results in overexpression of alkane hydroxylase in a distinct cytoplasmic membrane subtraction
Nieboer, M., Kingma, J., & Witholt, B. (1993) · Molecular Microbiology · doi:10.1111/j.1365-2958.1993.tb01649.x · Cited by 46
Asymmetric incorporation of dietary n-3 fatty acids into membrane aminophospholipids of human erythrocytes.
Knapp, H. R., Hullin, F., & Salem, N. (1994) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39971-5 · Cited by 46
Cholesterol transfer between lipid vesicles. Effect of phospholipids and gangliosides
Thomas, P. D., & Poznansky, M. J. (1988) · Biochemical Journal · doi:10.1042/bj2510055 · Cited by 46
The physical state of the intracytoplasmic membrane of Rhodopseudomonas sphaeroides and its relationship to the cell division cycle.
Fraley, R. T., Yen, G. S. L., Lueking, D. R., et al. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37754-2 · Cited by 46
Possible involvement of cyclic AMP and calcium ion in prostaglandin E1-induced elevation of c-myc mRNA levels in Swiss 3T3 fibroblasts.
Yamashita, T., Tsuda, T., Hamamori, Y., & Takai, Y. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75970-5 · Cited by 46
Phospholipids of adrenal cortex mitochondria and the steroid hydroxylases: The lipid-environment of cytochrome P-450
Wang, H., Pfeiffer, D. R., Kimura, T., & Tchen, T. T. (1974) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(74)80361-x · Cited by 46
Changes in cell permeability following a marked reduction of saturated fatty acid content of Escherichia coli K-12
Davis, M.-T. B., & Silbert, D. F. (1974) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(74)90147-3 · Cited by 46
Pulmonary phospholipid biosynthesis Properties of a stable microsomal glycerophosphate acyltransferase preparation from rabbit lung
Hendry, A. T., & Possmayer, F. (1974) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(74)90249-5 · Cited by 46
Incubation of acetylated low-density lipoprotein with cholesterol-rich dispersions enhances cholesterol uptake by macrophages
McCloskey, H. M., Rothblat, G. H., & Glick, J. M. (1987) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(87)90033-6 · Cited by 46
The degradation of platelet‐activating factor and related lipids: Susceptibility to phospholipases C and D
Wilcox, R. W., Wykle, R. L., Schmitt, J. D., et al. (1987) · Lipids · doi:10.1007/bf02535534 · Cited by 46
Rapid Transmembrane Movement of Newly Synthesized Phosphatidylethanolamine across the Inner Membrane of Escherichia coli
Huijbregts, R. P. H., de Kroon, A. I. P. M., & KRUIJFF, B. D. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.18936 · Cited by 46
Composition and physical properties of lipids from plasma membranes of dog kidney
Carmel, G., Rodrigue, F., Carrière, S., et al. (1985) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(85)90557-7 · Cited by 46
Annexin-mediated membrane fusion of human neutrophil plasma membranes and phospholipid vesicles
Oshry, L. J., Meers, P. R., Mealy, T. R., et al. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90192-b · Cited by 46
Chemical identification and enzymatic synthesis of a newly discovered lipid class—Hydroxyalkylglycerols
Kasama, K., Rainey, W. T., & Snyder, F. F. C. (1973) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(73)90020-9 · Cited by 46
Does diamide treatment of intact human erythrocytes cause a loss of phospholipid asymmetry?
Franck, P., den Kamp, J. A. F. O., Roelofsen, B., et al. (1986) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(86)90106-9 · Cited by 46
Changes in the biochemical composition of the pyloric caeca of female seastars,Asterias rubens, during their annual reproductive cycle
Oudejans, R. C. H. M., van der Sluis, I., & van der Plas, A. J. (1979) · Marine Biology · doi:10.1007/bf00952431 · Cited by 46
Growth Hormone Stimulates the Formation ofsn-1,2 Diacylglycerol in Rat Hepatocytes
Johnson, R. M., Napier, M. A., CRONIN, M. J., et al. (1990) · Endocrinology · doi:10.1210/endo-127-5-2099 · Cited by 46
Suppression of aortic atherosclerosis in cholesterol-fed rabbits by purified rabbit interferon.
Wilson, A. C., Schaub, R. G., Goldstein, R. C., et al. (1990) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.10.2.208 · Cited by 46
Phosphatidylinositol from ethanol-fed rats confers membrane tolerance to ethanol.
Taraschi, T. F., Ellingson, J. S., Wu, A., et al. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.24.9398 · Cited by 46
The phospholipids of rabbit type II alveolar epithelial cells: Comparison with lung lavage, lung tissue, alveolar macrophages, and a human alveolar tumor cell line
Rooney, S. A., Nardone, L. L., Shapiro, D. L., et al. (1977) · Lipids · doi:10.1007/bf02533629 · Cited by 46
Inhibition of eicosanoid and PAF formation by dexamethasone in rat inflammatory polymorphonuclear neutrophils may implicate lipocortin ‘s’
Fradin, A., Rothhut, B., Poincelot-Canton, B., et al. (1988) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(88)90288-3 · Cited by 46
Preferential hydrolysis of peroxidized phospholipid by lysosomal phospholipase C
Gamache, D. A., Fawzy, A. A., & Franson, R. C. (1988) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(88)90252-4 · Cited by 46
Lipid Peroxide, α-Tocopherol and Retinoid Levels in Plasma and Liver of Rats Fed Diets Containing β-Carotene and 13-cis-Retinoic Acid
Alam, S. Q., & Alam, B. S. (1983) · Journal of Nutrition · doi:10.1093/jn/113.12.2608 · Cited by 46
Thrombin and C-kinase activators potentiate calcium-stimulated arachidonic acid release in human platelets
Halenda, S. P., & Rehm, A. G. (1987) · Biochemical Journal · doi:10.1042/bj2480471 · Cited by 46
Isolation and purification of cardiolipin from beef heart.
Smaal, E. B., Romijn, D., van Kessel, W. S. M. G., et al. (1985) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34352-2 · Cited by 46
Effects of dietary sunflowerseed oil and marine oil on platelet membrane fluidity, arterial thrombosis, and platelet responses in rats☆
Rand, M. L., Hennissen, A. A. H. M., & Hornstra, G. (1986) · Atherosclerosis · doi:10.1016/0021-9150(86)90101-2 · Cited by 46
Analysis of pulmonary surfactant apoproteins by isoelectric focusing
Katyal, S. L., & Singh, G. (1984) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(84)90007-9 · Cited by 46
Relationship between phosphoinositide kinase activities and protein tyrosine phosphorylation in plasma membranes from A431 cells
Payrastre, B., Plantavid, M. M., Breton, M., et al. (1990) · Biochemical Journal · doi:10.1042/bj2720665 · Cited by 46
Biosynthesis of platelet activating factor. Substrate specificity of 1-alkyl-2-lyso-sn-glycero-3-phosphocholine:acetyl-CoA acetyltransferase in rat spleen microsomes.
Lee, T. C. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39128-7 · Cited by 46
Apo E-mediated uptake and degradation of normal very low density lipoproteins by human monocyte/macrophages: A saturable pathway distinct from the LDL receptor
Wang‐Iverson, P., Ginsberg, H. N., Peteanu, L. A., Le, N., & Brown, W. V. (1985) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(85)90645-x · Cited by 46
The mitochondrial fatty acid synthesizing system: General properties and acetate incorporation into monoenoic acids
Barron, E. J. (1966) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(66)90113-5 · Cited by 46
The metabolism of glycerol in the locust Schistocerca gregaria during flight
Candy, D. J., Hall, L. J., & Spencer, I. M. (1976) · Journal of Insect Physiology · doi:10.1016/0022-1910(76)90180-3 · Cited by 46
Modification of glycerolipid metabolism in L-M fibroblasts by an unnatural amino-alcohol, N-isopropylethanolamine
Blank, M. L., Piantadosi, C. A., Ishaq, K. S., et al. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(75)90419-2 · Cited by 46
Calcium-independent phospholipase A2 in rat tissue cytosols
Pierik, A. J., Nijssen, J. G., Aarsman, A. J., et al. (1988) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(88)90264-0 · Cited by 46
Measurement of serum apolipoprotein B by radioimmunoassay
Karlin, J. B., Juhn, D. J., Scanu, A. M., & Rubenstein, A. H. (1978) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1978.tb00803.x · Cited by 46
Studies on the heterogeneity of sarcoplasmic reticulum vesicles
Sarzała, M. G., & Michalak, M. (1978) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(78)90175-x · Cited by 46
Inhibitory Effect of Platelet-Activating Factor (PAF) on Luteinizing Hormone-Releasing Hormone and Somatostatin Release From Rat Median Eminencein VitroCorrelated with the Characterization of Specific PAF Receptor Sites in Rat Hypothalamus
Junier, M., TIBERGHIEN, C., Rougeot, C., et al. (1988) · Endocrinology · doi:10.1210/endo-123-1-72 · Cited by 46
Auxin-stimulated ATPase in membrane fractions from pumpkin hypocotyls (Cucurbita maxima L.)
Scherer, G. F. E. (1981) · Planta · doi:10.1007/bf00386536 · Cited by 46
Human phagocytes have multiple lipid A-binding sites
Golenbock, D. T., Hampton, R. Y., Raetz, C. R., et al. (1990) · Infection and Immunity · doi:10.1128/iai.58.12.4069-4075.1990 · Cited by 46
Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3’-kinase activity in rats
Le Foll, C., Corporeau, C., Le Guen, V., Gouygou, J.-P., Bergé, J.-P., & Delarue, J. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00446.2006 · Cited by 45
Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats
Bernardi, J. R., Ferreira, C. F., Senter, G., Krolow, R., de Aguiar, B. W., Portella, A. K., Kauer-Sant'Anna, M., Kapczinski, F., Dalmaz, C., Goldani, M. Z., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062031 · Cited by 43
Effect of the Incorporation of Lysozyme on the Properties of Jackfruit Starch Films
Bonomo, R. C. F., Santos, T. A., Santos, L. S., et al. (2017) · Journal of Polymers and the Environment · doi:10.1007/s10924-016-0902-4 · Cited by 45

Authors: Bligh, E. G., & Dyer, W. J.
Venue: Canadian Journal of Biochemistry and Physiology
Publisher: Canadian Science Publishing
Published: 1959-08-01
Volume: 37
Issue: 8
Pages: 911-917
ISSN: 0576-5544 (ISSN-L)
DOI: 10.1139/o59-099
OpenAlex: W2152311269
Cited by: 54,751
References: 5
Citations by year: 2026: 1149 · 2025: 1534 · 2024: 1685 · 2023: 1749 · 2022: 1802 · 2021: 2073 · 2020: 2152 · 2019: 1870 · 2018: 1737 · 2017: 1784 · 2016: 1780 · 2015: 1800 · 2014: 1786 · 2013: 1758 · 2012: 1551
FWCI: 8.73
Type: journal article
Language: en
Open access: closed
Licence: www.nrcresearchpress.com/page/about/CorporateTextAndDataMining (tdm)
Locations: Canadian Journal of Biochemistry and Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords: lipid extraction, lipid purification, chloroform-methanol extraction, frozen fish, lipid degradation, fish muscle, tissue homogenization, rapid extraction method
MeSH terms: Fishes, Lipids

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks