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Cited by 223Characterization and Applications of Magnetic NanoparticlesMagnetic Properties and Synthesis of FerritesGeomagnetism and Paleomagnetism Studies

Citric-acid-coated magnetite nanoparticles for biological applications

Răcuciu, M., Creangă, D. E., Airinei, A.·2006·The European Physical Journal E
DOI 10.1140/epje/i2006-10051-y
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Abstract

Water-based magnetic fluids, generally intended for biomedical applications, often have various coating molecules that make them stable and compatible with biological liquids. Magnetic fluids containing iron oxide particles have been prepared by a co-precipitation method, using citric acid as stabilizer. The magnetic particles of the magnetic fluids were obtained by chemical precipitation from ferric (FeCl(3)) and ferrous salts (FeSO(4) or FeCl(2)) in alkali medium (ammonia hydroxide). Citric acid was used to stabilize the magnetic-particle suspension. Physical tests were performed in order to determine various microstructural and rheological features. Transmission electron microscopy was the main investigation method for assessing the magnetic-particle size. The dimensional distribution of the magnetic-particle physical diameter was analyzed using the box-plot statistical method while infrared absorption spectra were used to study the colloidal particle structure. The magnetic-fluid density (picnometric method), viscosity (capillary method) and surface tension (stalagmometric method) were measured using standard methods.

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  • Prototypic examples of materials used to coat iron oxide nanoparticles are polymers, fatty acids, amino acids, metals, and oxides.

    “Prototypic examples of materials used to coat iron oxide nanoparticles are polymers [28, 47, 50], fatty acids (like oleic acid, stearic acid, lauric acid and dodecylphosphonic acid) [51–55], amino acids (like phenyl alanine, tyrosine, arginine, lysine and cysteine) [56–58],_metals (like gold, gadolinium and silver) [59–61] and oxides (like silica and TiO2) [62–64].”

    From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [52]

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Authors
Răcuciu, M., Creangă, D. E., & Airinei, A.
Affiliations
  • Lucian Blaga University of Sibiu (RO)
  • Institutul de Chimie Macromoleculară Petru Poni (RO)
Corresponding author
Răcuciu, M.
ORCID
Venue
The European Physical Journal E
Publisher
Springer Science and Business Media LLC
Published
2006-10
Volume
21
Issue
2
Pages
117-121
ISSN
  • 1292-8941 (ISSN-L)
  • 1292-895X
DOI
10.1140/epje/i2006-10051-y
OpenAlex
W2056393732
Cited by
223
References
19
Citations by year
2026: 3 · 2025: 7 · 2024: 8 · 2023: 9 · 2022: 17 · 2021: 13 · 2020: 16 · 2019: 28 · 2018: 13 · 2017: 16 · 2016: 11 · 2015: 16 · 2014: 7 · 2013: 14 · 2012: 16
FWCI
3.06
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • The European Physical Journal E (publishedVersion)
  • PubMed (publishedVersion)
  • Springer Link (Chiba Institute of Technology) (submittedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
  • Physical Sciences › Materials Science › Materials Chemistry › Magnetic Properties and Synthesis of Ferrites
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Geomagnetism and Paleomagnetism Studies
Keywords
Fe3O4 nanoparticles, citric acid coating, ferrofluids, iron oxide nanoparticles, co-precipitation synthesis, colloidal stability, particle size distribution, rheology, viscosity, density, surface tension, biomedical applications
MeSH terms
Biomedical Engineering, Colloids, Ferric Compounds, Ferrous Compounds, Hydroxides, Magnetics, Materials Testing, Particle Size, Chemical Precipitation, Surface Tension, Viscosity, Water, Citric Acid, Microscopy, Electron, Transmission, Nanoparticles, Ammonium Hydroxide

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