INTEGRIN-MEDIATED CCN FUNCTIONS
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
CCN1's varied and sometimes opposite cellular effects are due at least partly to different activities mediated by direct binding to distinct integrins in different cell types and contexts.
“can be ascribed, as least in part, to disparate activities mediated through its direct binding to distinct integrins in different cell types and contexts”
From CCN1/CYR61: the very model of a modern matricellular protein (2011) · cites this paper as [53]
CCN1 functions are mediated primarily through binding to distinct integrins.
“The functions of CCN proteins are mediated primarily through their binding to distinct integrins [53]”
From CCN1/CYR61: the very model of a modern matricellular protein (2011) · cites this paper as [53]
CCN1's disparate activities can now be attributed in large part to its interaction with distinct integrins and heparan sulfate proteoglycans in a cell-type and context-dependent manner.
“These disparate activities of CCN1 can now be attributed, in large parts, to its interaction with distinct integrins and heparan sulfate proteoglycans (HSPGs) in a cell-type and context-dependent manner”
From CCN1/CYR61: the very model of a modern matricellular protein (2011) · cites this paper as [53]
CCN1 supports cell adhesion and induces adhesive signaling in many adherent cell types.
“This observation led to the finding that CCN1 can support cell adhesion and induce adhesive signaling in many adherent cell types [18,53].”
From CCN1/CYR61: the very model of a modern matricellular protein (2011) · cites this paper as [53]
Cites
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Functions and mechanisms of action of CCN matricellular proteins
Chen, C.-C., & Lau, L. F. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.07.025 · Cited by 549 · see citing works
Self-citationCCN1/CYR61: the very model of a modern matricellular protein
Lau, L. F. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0778-3 · Cited by 338 · see citing works
Self-citationCytotoxicity of TNFα is regulated by integrin‐mediated matrix signaling
Chen, C., Young, J. L., Monzon, R. I., Chen, N., Todorović, V., & Lau, L. F. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601596 · Cited by 143 · see citing works
Self-citationThe matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts
Todorovicç, V., Chen, C.-C., Hay, N., & Lau, L. F. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200504015 · Cited by 132 · see citing works
Self-citationThe Matricellular Protein CCN1 Is Essential for Cardiac Development
Mo, F.-E., & Lau, L. F. (2006) · Circulation Research · doi:10.1161/01.res.0000248426.35019.89 · Cited by 112 · see citing works
Self-citationJuric, V., Chen, C.-C., & Lau, L. F. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00064-09 · Cited by 70 · see citing works
Self-citationLahousse, S. A., Wallace, D. G., Liu, D., Gaido, K. W., & Johnson, K. J. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl049 · Cited by 57 · see citing works
Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine‐rich protein 61
Walsh, C. T., Radeff‐Huang, J., Matteo, R., Hsiao, A., Subramaniam, S., Stupack, D., & Brown, J. H. (2008) · The FASEB Journal · doi:10.1096/fj.08-113266 · Cited by 47 · see citing works
Jones, J. A. M., Gray, M. R., Oliveira, B. E., Koch, M., & Castellot, J. J. (2007) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-007-0012-0 · Cited by 33 · see citing works
The matrix protein CCN1/CYR61 is required for αVβ5‐mediated cancer cell migration
Jandová, J., Beyer, T. E., Meuillet, E. J., & Watts, G. S. (2012) · Cell Biochemistry and Function · doi:10.1002/cbf.2853 · Cited by 26 · see citing works
Hsu, P., Su, B.-C., Kuok, Q.-Y., & Mo, F. (2013) · Cardiovascular Research · doi:10.1093/cvr/cvt001 · Cited by 23 · see citing works
Promotion of attachment of human bone marrow stromal cells by CCN2
Ono, M., Kubota, S., Fujisawa, T., Sonoyama, W., Kawaki, H., Akiyama, K., Oshima, M., Nishida, T., Yoshida, Y., Suzuki, K., et al. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.03.052 · Cited by 22 · see citing works
Temporal and spatial expression of CCN genes in zebrafish
Fernando, C. A., Conrad, P. A., Bartels, C. F., Marquès‐Bonet, T., To, M., Balow, S. A., Nakamura, Y., & Warman, M. L. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22279 · Cited by 21 · see citing works
Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells
Dotterweich, J., Ebert, R., Kraus, S., Tower, R. J., Jakob, F. J., & Schütze, N. (2014) · Cell Communication and Signaling · doi:10.1186/1478-811x-12-36 · Cited by 17 · see citing works
The matricellular protein CCN5 regulates podosome function via interaction with integrin αvβ3
Myers, R. B., Lan, W., & Castellot, J. J. (2014) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-013-0218-2 · Cited by 14 · see citing works
CCN proteins, microenvironment, communication and signaling: why did we need a new journal?
Perbal, A., & Perbal, B. (2007) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-007-0007-x · Cited by 9 · see citing works
- Authors
- Lau, L. F., & Lam, S. C. T.
- Affiliations
- University of Illinois Chicago (US)
- Venue
- CCN Proteins
- Published
- 2005-06
- Pages
- 61-79
- OpenAlex
- W2483371726
- Cited by
- 16
- References
- 0
- Citations by year
- 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 4.81
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- IMPERIAL COLLEGE PRESS eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connective Tissue Growth Factor Research
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Health Sciences › Medicine › Rheumatology › Bone and Dental Protein Studies
- Keywords
- integrins, CCN proteins, connective tissue growth factor, integrin signaling, cell adhesion, extracellular matrix
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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