The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry
Abstract
Lipidomics aims to quantitatively define lipid classes, including their molecular species, in biological systems. Lipidomics has experienced rapid progress, mainly because of continuous technical advances in instrumentation that are now enabling quantitative lipid analyses with an unprecedented level of sensitivity and precision. The still-growing category of lipids includes a broad diversity of chemical structures with a wide range of physicochemical properties. Reflecting this diversity, different methods and strategies are being applied to the quantification of lipids. Here, I review state-of-the-art electrospray ionization tandem mass spectrometric approaches and direct infusion to quantitatively assess lipid compositions of cells and subcellular fractions. Finally, I discuss a few examples of the power of mass spectrometry–based lipidomics in addressing cell biological questions.
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Cites
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Molecular anatomy of a trafficking organelle
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Self-citationLipidomics reveals a remarkable diversity of lipids in human plasma
Quehenberger, O., Armando, A. M., Brown, A. H., Milne, S. B., Myers, D. S., Merrill, A. H., Bandyopadhyay, S., Jones, K. N., Kelly, S., Shaner, R. L., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m009449 · Cited by 1,341
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Regulation of human EGF receptor by lipids
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Cited by
Dysregulation of lipids in Alzheimer’s disease and their role as potential biomarkers
Wong, M. W., Braidy, N., Poljak, A., Pickford, R., Thambisetty, M., & Sachdev, P. S. (2017) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2017.01.008 · Cited by 223
Adaptation of Lipid Profiling in Depression Disease and Treatment: A Critical Review
Pinto, B., Conde, T., Domingues, I., & Domingues, M. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042032 · Cited by 51
Characterization and multiplexed quantification of derivatized aminophospholipids
Nie, S., Fhaner, C. J., Liu, S., Peake, D., Kiyonami, R., Huang, Y., & Reid, G. E. (2015) · International Journal of Mass Spectrometry · doi:10.1016/j.ijms.2015.07.002 · Cited by 18
Metadata
- Authors
- Brügger, B.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2014-06-02
- Volume
- 83
- Issue
- 1
- Pages
- 79-98
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2160775085
- Cited by
- 264
- References
- 8
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- closed
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