The DOI matches its Crossref record; 216 of the 216 references it cites were found in a registry or an index.
Membrane Electroporation and Electropermeabilization: Mechanisms and Models
Open accessAbstract
Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient increase in their plasma membrane permeability, allowing transmembrane transport of otherwise impermeant molecules. In recent years, large steps were made in the understanding of underlying events. Formation of aqueous pores in the lipid bilayer is now a widely recognized mechanism, but evidence is growing that changes to individual membrane lipids and proteins also contribute, substantiating the need for terminological distinction between electroporation and electropermeabilization. We first revisit experimental evidence for electrically induced membrane permeability, its correlation with transmembrane voltage, and continuum models of electropermeabilization that disregard the molecular-level structure and events. We then present insights from molecular-level modeling, particularly atomistic simulations that enhance understanding of pore formation, and evidence of chemical modifications of membrane lipids and functional modulation of membrane proteins affecting membrane permeability. Finally, we discuss the remaining challenges to our full understanding of electroporation and electropermeabilization.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The results from electroporation studies further support that ion channel activation and ion influx, and perhaps other effects such as cytoskeleton damage, can be used as biomarkers of responsiveness to TTFields, given that these phenomena are observed after exposure to electric fields [27,46,62,65].”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Electropores may form under external electric fields 9 and can also arise spontaneously in naturallyoccuring (particularly biological) systems due to transient transmembrane potentials arising from bilayer-surface charge flucuations 8,12,[22][23][24][25][26][27][28][29][30] .”
From Fusion of lipid membranes: an alternative pathway (2026) · cites this paper as [25]
Experimental — accuracy not yet measuredIn the citing paper
“After the first threshold is surpassed, it is thought that the Vm depolarizes the membrane sufficiently to trigger the formation of aqueous pores and stimulate other voltage-dependent processes such as ion channel activation and cytoskeletal disruption [62,65].”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
In the citing paper
“While it has been recognized for some time now that aqueous pore formation allows for increased permeability across the plasma membrane, recent studies suggest that chemical and structural changes in the lipids and proteins (such as ion channels) of the membrane itself also contribute to the mechanism of action [62].”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
In the citing paper
“Electroporation pulses can range from nanoseconds to milliseconds in duration and tend to form aqueous pores in the plasma membrane that are on the order of ~1 nm in radius [60,62,63,64].”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
In the citing paper
“An important component of this proposed mechanism, by which altering the plasma membrane through electric pulses leads to increased permeability, is that there are two “thresholds” which are not universal but rather particular to the parameters being used (i.e., cell type/size, membrane curvature, exposure time, temperature, transported molecule, and osmotic pressure) [62]. The first threshold is”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
In the citing paper
“For example, TTFields have been reported to activate Cav2+ channels [46], membrane distortions predicted by the bioelectrorheological model are likely another feature of TTFields’ actions [40], and membrane fenestration is a hallmark of reversible electroporation [62].”
From Permeabilizing Cell Membranes with Electric Fields (2021) · cites this paper as [62]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ayala, A., Muñoz, M., & Argüelles, S. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/360438 · Cited by 6,837
Free radicals, metals and antioxidants in oxidative stress-induced cancer
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680
Theory of electroporation: A review
Weaver, J. C., & Chizmadzhev, Y. A. (1996) · Bioelectrochemistry and Bioenergetics · doi:10.1016/s0302-4598(96)05062-3 · Cited by 1,639
Electroporation of cell membranes
Tsong, T. Y. (1991) · Biophysical Journal · doi:10.1016/s0006-3495(91)82054-9 · Cited by 1,096
Gennis, R. B. (1989) · Springer advanced texts in chemistry · doi:10.1007/978-1-4757-2065-5 · Cited by 1,036
High-efficiency gene transfer into skeletal muscle mediated by electric pulses.
Mir, L. M., Bureau, M., Gehl, J., Rangara, R., Rouy, D., Caillaud, J., Delaère, P., Branellec, D., Schwartz, B., & Scherman, D. (1999) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.96.8.4262 · Cited by 972
Electroporation-based technologies for medicine: principles, applications, and challenges.
Yarmush, M., Golberg, A., Serša, G., Kotnik, T., & Miklavčič, D. (2014) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071813-104622 · Cited by 813
Self-citationEffect of Lipid Peroxidation on the Properties of Lipid Bilayers: A Molecular Dynamics Study
Wong-ekkabut, J., Xu, Z., Triampo, W., Tang, I., Tieleman, D. P., & Monticelli, L. (2007) · Biophysical Journal · doi:10.1529/biophysj.107.112565 · Cited by 645
Teissié, J., Golzio, M., & Rols, M. (2005) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2005.05.006 · Cited by 623
Electroporation-based applications in biotechnology
Kotnik, T., Frey, W., Sack, M., Meglič, S. H., Peterka, M., & Miklavčič, D. (2015) · Trends in biotechnology · doi:10.1016/j.tibtech.2015.06.002 · Cited by 613
Self-citationReversible electrical breakdown of lipid bilayers: formation and evolution of pores
Glaser, R. W., Leikin, S., Chernomordik, L., Pastushenko, V. F., & Sokirko, A. V. (1988) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(88)90202-7 · Cited by 611
Israelachvili, J. N., & Pashley, R. M. (1984) · Journal of Colloid and Interface Science · doi:10.1016/s0021-9797(84)80070-3 · Cited by 590
Intracellular effect of ultrashort electrical pulses
Schoenbach, K. H., Beebe, S. J., & Buescher, E. S. (2001) · Bioelectromagnetics · doi:10.1002/bem.71 · Cited by 548
Schutt, E. G., Klein, D. H., Mattrey, R., & Riess, J. G. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200550 · Cited by 546
Abiror, I. G., Arakelyan, V. B., Chernomordik, L. V., Chizmadzhev, Y. A., Pastushenko, V. F., & Tarasevich, M. R. (1979) · Bioelectrochemistry and Bioenergetics · doi:10.1016/0302-4598(79)85005-9 · Cited by 540
Chang, D. C., & Reese, T. S. (1990) · Biophysical Journal · doi:10.1016/s0006-3495(90)82348-1 · Cited by 524
Membrane Electroporation: A Molecular Dynamics Simulation
Tarek, M. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.050617 · Cited by 516
Self-citationModeling Electroporation in a Single Cell
Krassowska, W., & Filev, P. D. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.094235 · Cited by 501
Actin Polymerization and ATP Hydrolysis
Korn, E. D., Carlier, M., & Pantaloni, D. (1987) · Science · doi:10.1126/science.3672117 · Cited by 470
The molecular basis of electroporation
Tieleman, D. P. (2004) · BMC Biochemistry · doi:10.1186/1471-2091-5-10 · Cited by 460
Simulation of Pore Formation in Lipid Bilayers by Mechanical Stress and Electric Fields
Tieleman, D. P., Leontiadou, H., Mark, A. E., & Marrink, . J. (2003) · Journal of the American Chemical Society · doi:10.1021/ja029504i · Cited by 459
Modeling Electroporation in a Single Cell. I. Effects of Field Strength and Rest Potential
DeBruin, K. A., & Krassowska, W. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)76973-0 · Cited by 449
Scheffer, H. J., Nielsen, K., de Jong, M. C., van Tilborg, A. A. J. M., Vieveen, J. M., Bouwman, R. A., Meijer, S., van Kuijk, C., van den Tol, P., & Meijerink, M. R. (2014) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2014.01.028 · Cited by 431
der Paal, J. V., Neyts, E. C., Verlackt, C. C. W., & Bogaerts, A. (2015) · Chemical Science · doi:10.1039/c5sc02311d · Cited by 421
Direct visualization at the single-cell level of electrically mediated gene delivery
Golzio, M., Teissié, J., & Rols, M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.022646499 · Cited by 413
Fundamentals of electroporative delivery of drugs and genes
Neumann, E., Kakorin, S., & Tœnsing, K. (1999) · Bioelectrochemistry and Bioenergetics · doi:10.1016/s0302-4598(99)00008-2 · Cited by 402
Electropermeabilization of mammalian cells. Quantitative analysis of the phenomenon
Rols, M., & Teissié, J. (1990) · Biophysical Journal · doi:10.1016/s0006-3495(90)82451-6 · Cited by 396
Electrical Breakdown of Bimolecular Lipid Membranes as an Electromechanical Instability
Crowley, J. M. (1973) · Biophysical Journal · doi:10.1016/s0006-3495(73)86017-5 · Cited by 392
Teissié, J., & Rols, M. (1993) · Biophysical Journal · doi:10.1016/s0006-3495(93)81052-x · Cited by 376
Reversible electrical breakdown of lipid bilayer membranes: A charge-pulse relaxation study
Benz, R., Beckers, F., & Zimmermann, U. (1979) · The Journal of Membrane Biology · doi:10.1007/bf01872858 · Cited by 370
Antitumor effectiveness of electrochemotherapy: A systematic review and meta-analysis
Mali, B. Č., Jarm, T., Snoj, M., Serša, G., & Miklavčič, D. (2012) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2012.08.016 · Cited by 353
Self-citationElectropermeabilization of Mammalian Cells to Macromolecules: Control by Pulse Duration
Rols, M., & Teissié, J. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)74060-3 · Cited by 348
Asymptotic model of electroporation
Neu, J. C., & Krassowska, W. (1999) · Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics · doi:10.1103/physreve.59.3471 · Cited by 325
Raso, J., Frey, W., Ferrari, G., Pataro, G., Knorr, D., Teissié, J., & Damijan Miklavčič, A. (2016) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2016.08.003 · Cited by 322
Electric field induced transient pores in phospholipid bilayer vesicles
Teissié, J., & Tsong, T. Y. (1981) · Biochemistry · doi:10.1021/bi00509a022 · Cited by 319
Kotnik, T., & Miklavčič, D. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.070771 · Cited by 318 · cited 2×
“As a result, with further shortening of the pulses from the submicrosecond to the nanosecond range, the amplitude of the TMV induced on the plasma membrane is increasingly attenuated (96, 98) and gradually becomes comparable to the TMV induced on organelle membranes in the cell interior (97).”
BackgroundResultHibino, M., Shigemori, M., Itoh, H., Nagayama, K., & Kinosita, K. (1991) · Biophysical Journal · doi:10.1016/s0006-3495(91)82212-3 · Cited by 310
Hibino, M., Itoh, H., & Kinosita, K. (1993) · Biophysical Journal · doi:10.1016/s0006-3495(93)81550-9 · Cited by 307
Freeman, S., Wang, M. A., & Weaver, J. C. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80453-9 · Cited by 286
Stability of lipid bilayers and red blood cell membranes
Litster, J. D. (1975) · Physics Letters A · doi:10.1016/0375-9601(75)90402-8 · Cited by 282
Golberg, A., Sack, M., Teissié, J., Pataro, G., Pliquett, U. F., Saulis, G., Töpfl, S., Damijan Miklavčič, A., Vorobiev, E., & Frey, W. (2016) · Biotechnology for Biofuels · doi:10.1186/s13068-016-0508-z · Cited by 280
Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility
Needham, D., & Hochmuth, R. M. (1989) · Biophysical Journal · doi:10.1016/s0006-3495(89)82898-x · Cited by 278
Ab Initio Molecular Dynamics Study of Dissociation of Water under an Electric Field
Saitta, A. M., Saija, F., & Giaquinta, P. V. (2012) · Physical Review Letters · doi:10.1103/physrevlett.108.207801 · Cited by 272
Electro-Deformation and Poration of Giant Vesicles Viewed with High Temporal Resolution
Riske, K. A., & Dimova, R. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.050310 · Cited by 272
Melikov, K., Frolov, V. A., Shcherbakov, A., et al. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76153-x · Cited by 268
The cytoskeleton and cell volume regulation
Pedersen, S. F., Hoffmann, E. K., & Mills, J. W. (2001) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(01)00429-9 · Cited by 266
Piggot, T. J., Holdbrook, D. A., & Khalid, S. (2011) · The Journal of Physical Chemistry B · doi:10.1021/jp207013v · Cited by 243
Plasma Membrane Voltage Changes during Nanosecond Pulsed Electric Field Exposure
Frey, W., White, J. A., Price, R. O., Blackmore, P. F., Joshi, R. P., Nuccitelli, R., Beebe, S. J., Schoenbach, K. H., & Kolb, J. F. (2006) · Biophysical Journal · doi:10.1529/biophysj.105.072777 · Cited by 242
Constant electric field simulations of the membrane potential illustrated with simple systems
Gumbart, J. C., Khalili‐Araghi, F., Sotomayor, M., et al. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2011.09.030 · Cited by 239
Induced Transmembrane Voltage and Its Correlation with Electroporation-Mediated Molecular Transport
Kotnik, T., Pucihar, G., & Damijan Miklavčič, A. (2010) · The Journal of Membrane Biology · doi:10.1007/s00232-010-9279-9 · Cited by 236
Self-citationGiant vesicles in electric fields
Dimova, R., Riske, K. A., Aranda-Espinoza, S., Bezlyepkina, N., Knorr, R. L., & Lipowsky, R. (2007) · Soft Matter · doi:10.1039/b703580b · Cited by 235
Levine, Z. A., & Vernier, P. T. (2010) · The Journal of Membrane Biology · doi:10.1007/s00232-010-9277-y · Cited by 232
Control by pulse parameters of electric field-mediated gene transfer in mammalian cells
Wolf, H., Rols, M., Boldt, E., Neumann, E., & Teissié, J. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80805-7 · Cited by 231
Clinical potential of electroporation for gene therapy and DNA vaccine delivery
Lambricht, L., Lopes, A., Kos, Š., et al. (2015) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2016.1121990 · Cited by 231
Kotnik, T., Miklavčič, D., & Slivnik, T. (1998) · Bioelectrochemistry and Bioenergetics · doi:10.1016/s0302-4598(97)00093-7 · Cited by 230
Self-citationReactive oxygen species at phospholipid bilayers: Distribution, mobility and permeation
Cordeiro, R. M. (2013) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2013.09.016 · Cited by 228
Gene Electrotransfer: A Mechanistic Perspective
Rosazza, C., Meglič, S. H., Zumbusch, A., Rols, M., & Miklavčič, D. (2016) · Current Gene Therapy · doi:10.2174/1566523216666160331130040 · Cited by 228
Self-citationThe membrane potential and its representation by a constant electric field in computer simulations.
Roux, B. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.136499 · Cited by 225
Dielectric Properties of Aqueous NaCl Solutions at Microwave Frequencies
Nörtemann, K., Hilland, J., & Kaatze, U. (1997) · The Journal of Physical Chemistry A · doi:10.1021/jp971623a · Cited by 221
The role of tryptophan side chains in membrane protein anchoring and hydrophobic mismatch
de Jesus, A. J., & Allen, T. W. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.09.009 · Cited by 220
Oxygen free radicals and redox biology of organelles
Moldovan, L., & Moldovan, N. I. (2004) · Histochemistry and Cell Biology · doi:10.1007/s00418-004-0676-y · Cited by 213
Barnett, A. S., & Weaver, J. C. (1991) · Bioelectrochemistry and Bioenergetics · doi:10.1016/0302-4598(91)87001-w · Cited by 210
Numerical Determination of Transmembrane Voltage Induced on Irregularly Shaped Cells
Pucihar, G., Kotnik, T., Valič, B., & Damijan Miklavčič, A. (2006) · Annals of Biomedical Engineering · doi:10.1007/s10439-005-9076-2 · Cited by 209
Self-citationGabriel, B., & Teissié, J. (1997) · Biophysical Journal · doi:10.1016/s0006-3495(97)78292-4 · Cited by 206
Napotnik, T. B., Reberšek, M., Vernier, P. T., Mali, B. Č., & Damijan Miklavčič, A. (2016) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2016.02.011 · Cited by 195
Oxidative effects of nanosecond pulsed electric field exposure in cells and cell-free media
Pakhomova, O. N., Алексеевна, Х. В., Bowman, A. M., Rodaitė‐Riševičienė, R., Saulis, G., Xiao, S. H., & Pakhomov, A. G. (2012) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2012.08.004 · Cited by 189
Model of Creation and Evolution of Stable Electropores for DNA Delivery
Smith, K. C., Neu, J. C., & Krassowska, W. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74334-9 · Cited by 189
Regulation of Cell Cytoskeleton and Membrane Mechanics by Electric Field: Role of Linker Proteins
Titushkin, I. A., & Cho, M. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2008.09.035 · Cited by 189
Tutorial: Electroporation of cells in complex materials and tissue
Rems, L., & Miklavčič, D. (2016) · Journal of Applied Physics · doi:10.1063/1.4949264 · Cited by 189
Self-citationMolecular Dynamics Simulations of Lipid Membrane Electroporation
Delemotte, L., & Tarek, M. (2012) · The Journal of Membrane Biology · doi:10.1007/s00232-012-9434-6 · Cited by 188
Self-citationAtomistic Simulations of Pore Formation and Closure in Lipid Bilayers
Bennett, W. F., Sapay, N., & Tieleman, D. P. (2014) · Biophysical Journal · doi:10.1016/j.bpj.2013.11.4486 · Cited by 187
The resealing process of lipid bilayers after reversible electrical breakdown
Benz, R., & Zimmermann, U. S. (1981) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(81)90542-3 · Cited by 183
Kinetics of Transmembrane Transport of Small Molecules into Electropermeabilized Cells
Pucihar, G., Kotnik, T., Damijan Miklavčič, A., & Teissié, J. (2008) · Biophysical Journal · doi:10.1529/biophysj.108.135541 · Cited by 179
Self-citationPassive ion permeability of lipid membranes modelled via lipid-domain interfacial area.
Cruzeiro-Hansson, L., & Mouritsen, O. G. (1988) · Biochimica et Biophysica Acta · doi:10.1016/0005-2736(88)90316-1 · Cited by 175
Membrane electroporation: The absolute rate equation and nanosecond time scale pore creation
Vasilkoski, Z., Esser, A. T., Gowrishankar, T. R., & Weaver, J. C. (2006) · Physical Review E · doi:10.1103/physreve.74.021904 · Cited by 175
Nanosecond electric pulses cause mitochondrial membrane permeabilization in Jurkat cells
Napotnik, T. B., Wu, Y., Gundersen, M. A., Damijan Miklavčič, A., & Vernier, P. T. (2011) · Bioelectromagnetics · doi:10.1002/bem.20707 · Cited by 171
Gabriel, B., & Teissié, J. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb18962.x · Cited by 162
On electroporation of cell membranes and some related phenomena
Tsong, T. Y. (1990) · Bioelectrochemistry and Bioenergetics · doi:10.1016/0302-4598(90)80028-h · Cited by 158
Gabriel, B., & Teissié, J. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77370-4 · Cited by 156
Second-order model of membrane electric field induced by alternating external electric fields
Kotnik, T., & Miklavcic, D. (2000) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.855935 · Cited by 150 · cited 1×
“As a result, with further shortening of the pulses from the submicrosecond to the nanosecond range, the amplitude of the TMV induced on the plasma membrane is increasingly attenuated (96, 98) and gradually becomes comparable to the TMV induced on organelle membranes in the cell interior (97).”
ResultMechanism of Electroporative Dye Uptake by Mouse B Cells
Neumann, E., Toensing, K., Kakorin, S., Budde, P. I., & Frey, J. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77771-9 · Cited by 148
Defective lysosomal exocytosis and plasma membrane repair in Chediak–Higashi/beige cells
Huynh, C. D. M., Roth, D., Ward, D. M., Kaplan, J., & Andrews, N. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405905101 · Cited by 148
Dimitrov, D. S. (1984) · The Journal of Membrane Biology · doi:10.1007/bf01872532 · Cited by 146
Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane
Vernier, P. T., Levine, Z. A., Wu, Y., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007966 · Cited by 142
Tekle, E., Oubrahim, H., Dzekunov, S. M., Kolb, J. F., Schoenbach, K. H., & Chock, P. B. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.054494 · Cited by 139
Quantitative model of small molecules uptake after in vitro cell electropermeabilization
Puc, M., Kotnik, T., Mir, L. M., et al. (2003) · Bioelectrochemistry · doi:10.1016/s1567-5394(03)00021-5 · Cited by 139
Self-citationJurkiewicz, P., Olżyńska, A., Cwiklik, L., Conte, E., Jungwirth, P., Megli, F. M., & Hof, M. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.05.020 · Cited by 136
Selective and asymmetric molecular transport across electroporated cell membranes.
Tekle, E., Astumian, R. D., & Chock, P. B. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.24.11512 · Cited by 135
Control by Osmotic Pressure of Voltage-Induced Permeabilization and Gene Transfer in Mammalian Cells
Golzio, M., Mora, M.-P., Raynaud, C., et al. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)78009-9 · Cited by 135
Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells
Paganin-Gioanni, A., Bellard, E., Escoffre, J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103519108 · Cited by 134
Pakhomov, A. G., Gianulis, E. C., Vernier, P. T., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2014.12.026 · Cited by 133
Leukemic cell intracellular responses to nanosecond electric fields
Chen, N., Schoenbach, K. H., Kolb, J. F., Swanson, R. J., Garner, A. L., Yang, J., Joshi, R. P., & Beebe, S. J. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.03.063 · Cited by 129
The endothelial cytoskeleton as a target of electroporation-based therapies
Kanthou, C., Kranjc, S., Sersa, G., Tozer, G., Zupanic, A., & Cemazar, M. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0410 · Cited by 129
Evidence of voltage-induced channel opening in Na/K ATPase of human erythrocyte membrane
Teissié, J., & Tsong, T. Y. (1980) · The Journal of Membrane Biology · doi:10.1007/bf01871155 · Cited by 127
Lopez, A., Rols, M., & Teissié, J. (1988) · Biochemistry · doi:10.1021/bi00404a023 · Cited by 127
Gurtovenko, A. A., & Vattulainen, I. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.094797 · Cited by 123
Stacey, M. W., Fox, P. M., Buescher, S., et al. (2011) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2011.06.002 · Cited by 119
Gascoyne, P. R. C., Pethig, R., Burt, J. P. H., & Becker, F. F. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90032-u · Cited by 114
Bilayer Deformation, Pores, and Micellation Induced by Oxidized Lipids
Boonnoy, P., Jarerattanachat, V., Karttunen, M., et al. (2015) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.5b02405 · Cited by 114
Massive oxidation of phospholipid membranes leads to pore creation and bilayer disintegration
Cwiklik, L., & Jungwirth, P. (2010) · Chemical Physics Letters · doi:10.1016/j.cplett.2010.01.010 · Cited by 112
Imaging the dynamics of individual electropores
Sengel, J. T., & Wallace, M. I. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1517437113 · Cited by 110
Craviso, G. L., Choe, S., Chatterjee, P., Chatterjee, I., & Vernier, P. T. (2010) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-010-9573-1 · Cited by 107
Pavlin, M., Leben, V., & Miklavčič, D. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.06.014 · Cited by 106
Self-citationRems, L., Viano, M., Kasimova, M. A., Damijan Miklavčič, A., & Tarek, M. (2018) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2018.07.018 · Cited by 104
Self-citationNumerical simulation of molecular uptake via electroporation
Li, J., & Lin, H. (2011) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2011.04.006 · Cited by 103
Electric Field-Driven Water Dipoles: Nanoscale Architecture of Electroporation
Tokman, M., Lee, J. H., Levine, Z. A., Ho, M.-C., Colvin, M. E., & Vernier, P. T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061111 · Cited by 100
Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses
Son, R. S., Smith, K. C., Gowrishankar, T. R., Vernier, P. T., & Weaver, J. C. (2014) · The Journal of Membrane Biology · doi:10.1007/s00232-014-9699-z · Cited by 99
The effect of lipid oxidation on the water permeability of phospholipids bilayers
Lis, M., Wizert, A., Przybyło, M., et al. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c1cp21009b · Cited by 99
Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro
Rosazza, C., Deschout, H. G., Buntz, A., Braeckmans, K., Rols, M., & Zumbusch, A. (2016) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2015.59 · Cited by 99
Modeling Membranes under a Transmembrane Potential
Delemotte, L., Dehez, F. L., Treptow, W. L., et al. (2008) · The Journal of Physical Chemistry B · doi:10.1021/jp710846y · Cited by 97
Rols, M., & Teissié, J. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90272-n · Cited by 97
Gabriel, B., & Teissié, J. (1995) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(95)00021-j · Cited by 97
Ion Transport across Transmembrane Pores
Leontiadou, H., Mark, A. E., & Marrink, . J. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.101295 · Cited by 96
Membrane pore formation in atomistic and coarse-grained simulations
Kirsch, S. A., & Böckmann, R. A. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2015.12.031 · Cited by 93
The temperature effect during pulse application on cell membrane fluidity and permeabilization
Kandušer, M., Šentjurc, M., & Miklavčič, D. (2008) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2008.04.012 · Cited by 92
Self-citationEhrenberg, B., Farkas, D. L., Fluhler, E., et al. (1987) · Biophysical Journal · doi:10.1016/s0006-3495(87)83410-0 · Cited by 91
Breton, M., Delemotte, L., Silve, A., Mir, L. M., & Tarek, M. (2012) · Journal of the American Chemical Society · doi:10.1021/ja3052365 · Cited by 90
Self-citationFernández, M. L., Marshall, G., Sagués, F., & Reigada, R. (2010) · The Journal of Physical Chemistry B · doi:10.1021/jp911605b · Cited by 82
Ren, W., Sain, N. M., & Beebe, S. J. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.04.094 · Cited by 82
Lira, R. B., Dimova, R., & Riske, K. A. (2014) · Biophysical Journal · doi:10.1016/j.bpj.2014.08.009 · Cited by 82
Casciola, M., Bonhenry, D., Liberti, M., et al. (2014) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2014.03.009 · Cited by 80
Pakhomov, A. G., Xiao, S. H., Pakhomova, O. N., Semenov, I., Kuipers, M. A., & Ibey, B. L. (2014) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2014.01.004 · Cited by 80
Ĉemazˆr, M., Jarm, T., Miklavčič, D., et al. (1998) · Electro- and Magnetobiology · doi:10.3109/15368379809022571 · Cited by 80
Self-citationRole of Lipid Peroxidation in Electroporation-Induced Cell Permeability
Maccarrone, M., Bladergroen, M. R., Rosato, N., et al. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1519 · Cited by 79
Influence of cholesterol on electroporation of bilayer lipid membranes: chronopotentiometric studies
Koronkiewicz, S., & Kalinowski, S. (2004) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2004.01.005 · Cited by 78
Perrier, D. L., Rems, L., & Boukany, P. E. (2017) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2017.04.016 · Cited by 76
Self-citationLeguèbe, M., Silve, A., Mir, L. M., et al. (2014) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2014.06.027 · Cited by 75
van Uitert, I., Gac, S. L., & van den Berg, A. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2009.10.003 · Cited by 74
Casciola, M., & Tarek, M. (2016) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2016.03.022 · Cited by 74
Self-citationBreton, M., & Mir, L. M. (2017) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2017.09.005 · Cited by 73
Nesin, V., Bowman, A. M., Xiao, S. H., & Pakhomov, A. G. (2011) · Bioelectromagnetics · doi:10.1002/bem.21696 · Cited by 72
Long-Lived Macropinocytosis Takes Place in Electropermeabilized Mammalian Cells
Rols, M., Femenia, P., & Teissié, J. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1300 · Cited by 72
Millisecond measurement of transport during and after an electroporation pulse
Prausnitz, M. R., Corbett, J. D., Gimm, J. A., et al. (1995) · Biophysical Journal · doi:10.1016/s0006-3495(95)80363-2 · Cited by 70
Electroporation Enhances Cell Membrane Peroxidation and Luminescence
Maccarrone, M., Rosato, N., & Agrò, A. F. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1033 · Cited by 69
Size-controlled nanopores in lipid membranes with stabilizing electric fields
Fernández, M. L., Risk, M. R., Reigada, R., et al. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.05.122 · Cited by 68
Electrohydrodynamic instability in plane layers of fluid
Michael, D. H., & O’Neill, M. E. (1970) · Journal of Fluid Mechanics · doi:10.1017/s0022112070000757 · Cited by 68
Reale, R., English, N. J., Gárate, J. A., Marracino, P., Liberti, M., & Apollonio, F. (2013) · The Journal of Chemical Physics · doi:10.1063/1.4832383 · Cited by 68
Pakhomov, A. G., Semenov, I., Casciola, M., & Xiao, S. H. (2017) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2017.04.016 · Cited by 68
Visualization of Membrane Loss during the Shrinkage of Giant Vesicles under Electropulsation
Portet, T., Febrer, F. C. I., Escoffre, J., et al. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.02.063 · Cited by 67
Electropermeabilization of endocytotic vesicles in B16 F1 mouse melanoma cells
Napotnik, T. B., Reberšek, M., Kotnik, T., Lebrasseur, É., Cabodevila, G., & Damijan Miklavčič, A. (2010) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-010-0599-9 · Cited by 67
Self-citationIrreversible electroporation for the treatment of cardiac arrhythmias
Sugrue, A. M., Maor, E., Ivorra, A., Vaidya, V. R., Witt, C. M., Kapa, S., & Asirvatham, S. J. (2018) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2018.1459185 · Cited by 67
A theory of the electric field-induced phase transition of phospholipid bilayers
Sugár, I. P. (1979) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(79)90420-6 · Cited by 66
Weight and Body Temperature in Mammals
MORRISON, P. R., & Ryser, F. A. (1952) · Science · doi:10.1126/science.116.3009.231 · Cited by 65
Garcia, P. A., Kos, B., Rossmeisl, J. H., et al. (2017) · Medical Physics · doi:10.1002/mp.12401 · Cited by 65
Evaluation of Cell Membrane Electropermeabilization by Means of a Nonpermeant Cytotoxic Agent
Kotnik, T., Maček-Lebar, A., Miklavčič, D., et al. (2000) · BioTechniques · doi:10.2144/00285st05 · Cited by 64
Self-citationElectroporation of archaeal lipid membranes using MD simulations
Polak, A., Tarek, M., Tomšič, M., et al. (2014) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2013.12.006 · Cited by 64
Self-citationPlant actin controls membrane permeability
Hohenberger, P., Eing, C., Straessner, R., Durst, S., Frey, W., & Nick, P. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2011.05.019 · Cited by 64
On the Electroporation Thresholds of Lipid Bilayers: Molecular Dynamics Simulation Investigations
Polak, A., Bonhenry, D., Dehez, F. L., et al. (2013) · The Journal of Membrane Biology · doi:10.1007/s00232-013-9570-7 · Cited by 62
Quantification of Electroporative Uptake Kinetics and Electric Field Heterogeneity Effects in Cells
Kennedy, S. M., Ji, Z. J., Hedstrom, J., Booske, J. H., & Hagness, S. C. (2008) · Biophysical Journal · doi:10.1529/biophysj.106.103218 · Cited by 61
Nanosecond electric pulses trigger actin responses in plant cells
Berghöfer, T., Eing, C., Flickinger, B., et al. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.07.072 · Cited by 59
Variability of the Minimal Transmembrane Voltage Resulting in Detectable Membrane Electroporation
Towhidi, L., Kotnik, T., Pucihar, G., Firoozabadi, M., Mozdarani, H., & Damijan Miklavčič, A. (2008) · Electromagnetic Biology and Medicine · doi:10.1080/15368370802394644 · Cited by 58
Self-citationBurke, R. C., Bardet, S. M., Carr, L., Romanenko, S., Arnaud-Cormos, D., Leveque, P., & O'Connor, R. P. (2017) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2017.07.004 · Cited by 58
Meulenberg, C. J. W., Todorović, V., & Čemažar, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052713 · Cited by 57
Molecular Dynamics Simulations of Ion Conductance in Field-Stabilized Nanoscale Lipid Electropores
Ho, M.-C., Casciola, M., Levine, Z. A., et al. (2013) · The Journal of Physical Chemistry B · doi:10.1021/jp401722g · Cited by 57
Čemažar, M., Serša, G., Frey, W., Miklavčič, D., & Teissié, J. (2018) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2018.03.005 · Cited by 56
Self-citationMolecular Dynamics Simulations of Membrane–Sugar Interactions
Kapla, J., Wohlert, J., Stevensson, B., et al. (2013) · The Journal of Physical Chemistry B · doi:10.1021/jp402385d · Cited by 55
Molecular Dynamics Study of Oxidized Lipid Bilayers in NaCl Solution
Jarerattanachat, V., Karttunen, M., & Wong-ekkabut, J. (2013) · The Journal of Physical Chemistry B · doi:10.1021/jp4040612 · Cited by 54
Shirakashi, R., Sukhorukov, V. L., Tanasawa, I., et al. (2004) · International Journal of Heat and Mass Transfer · doi:10.1016/j.ijheatmasstransfer.2004.04.007 · Cited by 53
The current-voltage relation of an aqueous pore in a lipid bilayer membrane
Barnett, A. (1990) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(90)90184-p · Cited by 52
Ultrastructural modifications of cell membranes induced by “electroporation” on melanoma xenografts
Spugnini, E. P., Arancia, G., Porrello, A., et al. (2007) · Microscopy Research and Technique · doi:10.1002/jemt.20504 · Cited by 51
Electroporation of Asymmetric Phospholipid Membranes
Gurtovenko, A. A., & Lyulina, A. S. (2014) · The Journal of Physical Chemistry B · doi:10.1021/jp5028355 · Cited by 51
Calcium and Phosphatidylserine Inhibit Lipid Electropore Formation and Reduce Pore Lifetime
Levine, Z. A., & Vernier, P. T. (2012) · The Journal of Membrane Biology · doi:10.1007/s00232-012-9471-1 · Cited by 51
Transport of charged small molecules after electropermeabilization — drift and diffusion
Sozer, E. B., Pocetti, C. F., & Vernier, P. T. (2018) · BMC Biophysics · doi:10.1186/s13628-018-0044-2 · Cited by 51
Effect of Pulsed Electric Field on Membrane Lipids and Oxidative Injury of Salmonella typhimurium
Yun, O., Zeng, X., Brennan, C. S., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081374 · Cited by 50
Irreversible electroporation ablation for atrial fibrillation
Wojtaszczyk, A., Caluori, G., Pešl, M., Melajová, K., & Stárek, Z. (2018) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.13454 · Cited by 50
Nesin, V., & Pakhomov, A. G. (2012) · Bioelectromagnetics · doi:10.1002/bem.21703 · Cited by 49
The current-voltage relation for electropores with conductivity gradients
Li, J., & Lin, H. (2010) · Biomicrofluidics · doi:10.1063/1.3324847 · Cited by 49
Electro-optics of membrane electroporation in diphenylhexatriene-doped lipid bilayer vesicles
Kakorin, S., Stoylov, S. P., & Neumann, E. (1996) · Biophysical Chemistry · doi:10.1016/0301-4622(95)00090-9 · Cited by 49
Destabilization induced by electropermeabilization analyzed by atomic force microscopy
Chopinet, L., Roduit, C., Rols, M., & Dague, É. (2013) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2013.05.035 · Cited by 47
Determining radical penetration of lipid bilayers with new lipophilic spin traps
Gamliel, A., Afri, M., & Frimer, A. A. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.028 · Cited by 47
Phospholipid-linked Coumarin: A Fluorescent Probe for Sensing Hydroxyl Radicals in Lipid Membranes
Soh, N., Makihara, K., Ariyoshi, T., Seto, D., Maki, T., Nakajima, H., Nakano, K., & Imato, T. (2008) · Analytical Sciences · doi:10.2116/analsci.24.293 · Cited by 47
Koronkiewicz, S., Kalinowski, S., & Bryl, K. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(02)00347-4 · Cited by 46
Evidence of Conducting Hydrophobic Nanopores Across Membranes in Response to an Electric Field
Dehez, F. L., Delemotte, L., Kramar, P., et al. (2014) · The Journal of Physical Chemistry C · doi:10.1021/jp4114865 · Cited by 46
Sozer, E. B., Levine, Z. A., & Vernier, P. T. (2017) · Scientific Reports · doi:10.1038/s41598-017-00092-0 · Cited by 46
Chronopotentiometric studies of electroporation of bilayer lipid membranes
Kalinowski, S., Ibron, G., Bryl, K., et al. (1998) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(97)00222-8 · Cited by 44
Casciola, M., Kasimova, M. A., Rems, L., et al. (2016) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2016.01.006 · Cited by 44
Self-citationElectrochemical Reaction and Oxidation of Lecithin under Pulsed Electric Fields (PEF) Processing
Zhao, W., Yang, R., Liang, Q., et al. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf304236h · Cited by 44
Electroporation of heterogeneous lipid membranes
Reigada, R. (2013) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2013.10.008 · Cited by 43
Effects of Dimethyl Sulfoxide on Lipid Membrane Electroporation
Fernández, M. L., & Reigada, R. (2014) · The Journal of Physical Chemistry B · doi:10.1021/jp503502s · Cited by 41
Molecular-Level Characterization of Lipid Membrane Electroporation using Linearly Rising Current
Kramar, P., Delemotte, L., Lebar, A. M., et al. (2012) · The Journal of Membrane Biology · doi:10.1007/s00232-012-9487-6 · Cited by 41
Chen, W., Zhongsheng, Z., & Lee, R. C. (2005) · Burns · doi:10.1016/j.burns.2005.08.008 · Cited by 41
Destabilizing Giant Vesicles with Electric Fields: An Overview of Current Applications
Portet, T., Mauroy, C., Démery, V., et al. (2012) · The Journal of Membrane Biology · doi:10.1007/s00232-012-9467-x · Cited by 41
Electroporation Dependence on Cell Size: Optical Tweezers Study
Henslee, B. E., Morss, A., Hu, X. T., Lafyatis, G. P., & Lee, L. J. (2011) · Analytical Chemistry · doi:10.1021/ac1019649 · Cited by 41
Nonlinear current–voltage relationship of the plasma membrane of single CHO cells
Krassen, H., Pliquett, U. F., & Neumann, E. (2006) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2006.03.033 · Cited by 40
Electrochemotherapy to Metastatic Spinal Melanoma
Gasbarrini, A., Campos, W. K., Campanacci, L., et al. (2015) · Spine · doi:10.1097/brs.0000000000001125 · Cited by 39
Chen, W., Han, Y., Chen, Y., & Astumian, R. D. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77506-x · Cited by 38
Membrane Curvature and High-Field Electroporation of Lipid Bilayer Vesicles
Kakorin, S., Liese, T., & Neumann, E. (2003) · The Journal of Physical Chemistry B · doi:10.1021/jp022296w · Cited by 37
Ionic conductivity of electroporated lipid bilayer membranes
Kakorin, S., & Neumann, E. (2002) · Bioelectrochemistry · doi:10.1016/s1567-5394(02)00040-3 · Cited by 37
Xiao, D., Tang, L., Zeng, C., Wang, J., Luo, X., Yao, C., & Sun, C. (2010) · Cell Biology International · doi:10.1042/cbi20100464 · Cited by 36
Azan, A., Untereiner, V., Gobinet, C., Sockalingum, G. D., Breton, M., Piot, O., & Mir, L. M. (2017) · Scientific Reports · doi:10.1038/srep40448 · Cited by 36
A System for the Determination of Planar Lipid Bilayer Breakdown Voltage and Its Applications
Kramar, P., Miklavčič, D., & Lebar, A. M. (2009) · IEEE Transactions on NanoBioscience · doi:10.1109/tnb.2009.2022834 · Cited by 34
Self-citationSozer, E. B., Pocetti, C. F., & Vernier, P. T. (2017) · The Journal of Membrane Biology · doi:10.1007/s00232-017-9962-1 · Cited by 34
Electroporation of DC-3F Cells Is a Dual Process
Wegner, L. H., Frey, W., & Silve, A. (2015) · Biophysical Journal · doi:10.1016/j.bpj.2015.01.038 · Cited by 33
Yeo, S. K., & Liong, M. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5775 · Cited by 30
Cholesterol reduces membrane electroporation and electric deformation of small bilayer vesicles
Kakorin, S., Brinkmann, U., & Neumann, E. (2005) · Biophysical Chemistry · doi:10.1016/j.bpc.2005.05.001 · Cited by 30
Mussauer, H. (1999) · The Journal of Membrane Biology · doi:10.1007/s002329900542 · Cited by 29
Imaging potassium-flux through individual electropores in droplet interface bilayers
Szabo, M., & Wallace, M. I. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2015.07.009 · Cited by 29
Rems, L., Tarek, M., Casciola, M., et al. (2016) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2016.03.005 · Cited by 29
Self-citationSalomone, F., Breton, M., Leray, I., et al. (2014) · Molecular Pharmaceutics · doi:10.1021/mp500223t · Cited by 28
Control by Low Levels of Calcium of Mammalian Cell Membrane Electropermeabilization
Ciobanu, F., Golzio, M., Kovács, E., et al. (2017) · The Journal of Membrane Biology · doi:10.1007/s00232-017-9981-y · Cited by 28
Research works printed but not linked: 4
- Benov LC, 1994, Gen. Physiol. Biophys., 13, 85
- 10.1016/0021-9797(84)90177-2 · DOI
- Min B, 2005, Food Sci. Biotechnol., 14, 152
- Yang L, 2017, PLOS ONE, 12, e181002
Cited by
Sorted by citations
O’Connor, J., Garcia-Vaquero, M., Meaney, S., & Tiwari, B. K. (2022) · Marine Drugs · doi:10.3390/md20050317 · Cited by 81
Permeabilizing Cell Membranes with Electric Fields
Aguilar, A. A., Ho, M. C., Chang, E., Carlson, K. W., Natarajan, A., Marciano, T., Bomzon, Z., & Patel, C. B. (2021) · Cancers · doi:10.3390/cancers13092283 · Cited by 76
Direct transesterification of microalgae after pulsed electric field treatment
Papachristou, I., Zhang, S., Gorte, O., Ochsenreither, K., Wüstner, R., Nazarova, N., Frey, W., & Silve, A. (2023) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.7293 · Cited by 9
Fusion of lipid membranes: an alternative pathway
Jin, D., Li, Z., Roke, S., & Klein, J. (2026) · doi:10.64898/2026.02.19.706911
Metadata
- Authors
- Kotnik, T., Rems, L., Tarek, M., & Miklavčič, D.
- Affiliations
- University of Ljubljana (SI)
- Science for Life Laboratory (SE)
- Centre National de la Recherche Scientifique (FR)
- Faculty of Electrical Engineering, University of Ljubljana, SI-1000 Ljubljana, Slovenia;,
- Venue
- Annual Review of Biophysics
- Publisher
- Annual Reviews
- Published
- 2019-05-06
- Volume
- 48
- Issue
- 1
- Pages
- 63-91
- ISSN
- 1936-122X (ISSN-L)
- 1936-1238
- OpenAlex
- W2917550741
- Cited by
- 813
- References
- 216
- Citations by year
- 2026: 129 · 2025: 138 · 2024: 141 · 2023: 122 · 2022: 97 · 2021: 102 · 2020: 66 · 2019: 18
- FWCI
- 6.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annual Review of Biophysics (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Javna Agencija za Raziskovalno Dejavnost RS
- Centre National de la Recherche Scientifique
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Inactivation Methods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Atmospheric-Pressure Plasma Applications
- Keywords
- electroporation, plasma membrane permeability, lipid bilayers, transmembrane voltage, continuum model, atomistic simulation, electric pulses
- MeSH terms
- Cell Membrane, Cell Membrane Permeability, Humans, Lipid Bilayers, Membrane Lipids, Electroporation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
