Cited by 237Sleep and related disordersCircadian rhythm and melatoninSleep and Wakefulness Research

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Sleep and Circadian Functioning: Critical Mechanisms in the Mood Disorders?

Harvey, Allison G.·2011·Annual Review of Clinical Psychology

DOI 10.1146/annurev-clinpsy-032210-104550

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Abstract

Evidence for the importance of sleep in the mood disorders has mushroomed over the past decade. Among adolescents and adults with a mood disorder, sleep disturbance is a risk factor for episodes, can contribute to relapse, has an adverse impact on emotion regulation, is critical for cognitive functioning, compromises health, and may contribute to substance use comorbidity and suicidality. This evidence has triggered a shift away from viewing sleep disturbance as an epiphenomenon, toward viewing sleep disturbance as an important but under-recognized mechanism in the multifactorial cause and maintenance of the mood disorders. Because the biology underpinning the sleep and circadian system is an open system, readily influenced by inputs from the environment, sleep in the mood disorders represents a unique and exciting domain for interdisciplinary research across behavioral, social, cognitive, and neurobiological levels of explanation. Together, the accumulated evidence has informed a range of novel, powerful, simple, and inexpensive treatments with potential for massive improvements to public health, including improving quality of life, reducing length and severity of episodes, and reducing the risk of subsequent episodes in the large number of individuals who suffer from mood disorders.

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Authors: Harvey, A. G.
Affiliations: University of Bergen (NO)
Corresponding author: Harvey, Allison G.
ORCID: Harvey, Allison G.
Venue: Annual Review of Clinical Psychology
Publisher: Annual Reviews
Published: 2011-04-27
Volume: 7
Issue: 1
Pages: 297-319
ISSN: 1548-5943 (ISSN-L)
1548-5951
DOI: 10.1146/annurev-clinpsy-032210-104550
OpenAlex: W2123078083
Cited by: 237
References: 167
Citations by year: 2026: 16 · 2025: 13 · 2024: 13 · 2023: 9 · 2022: 10 · 2021: 19 · 2020: 16 · 2019: 12 · 2018: 20 · 2017: 16 · 2016: 20 · 2015: 23 · 2014: 14 · 2013: 17 · 2012: 12
FWCI: 2.06
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (R34MH080958)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Keywords: sleep disorders, circadian rhythm, mood disorders, depression, bipolar disorder, relapse, emotion regulation, cognitive function, substance use comorbidity, suicidality, sleep interventions
MeSH terms: Adolescent, Adult, Antidepressive Agents, Bipolar Disorder, Circadian Rhythm, Cognitive Dissonance, Major Depressive Disorder, Depressive Disorder, Major, Humans, Risk Factors, Sleep, Sleep Wake Disorders, Mood Disorders

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Sleep and Circadian Functioning: Critical Mechanisms in the Mood Disorders?

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