The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
Physical Models of Collective Cell Migration
Open accessAbstract
Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here, we provide a physical perspective of the mechanisms underlying collective cell migration. We begin with a catalog of the cell–cell and cell–substrate interactions that govern cell migration, which we classify into positional and orientational interactions. We then review the physical models that have been developed to explain how these interactions give rise to collective cellular movement. These models span the subcellular to the supracellular scales, and they include lattice models, phase-field models, active network models, particle models, and continuum models. For each type of model, we discuss its formulation, its limitations, and the main emergent phenomena that it has successfully explained. These phenomena include flocking and fluid–solid transitions, as well as wetting, fingering, and mechanical waves in spreading epithelial monolayers. We close by outlining remaining challenges and future directions in the physics of collective cell migration.
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Cites
The Physics of Liquid Crystals
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Collective cell migration in morphogenesis, regeneration and cancer
Friedl, P., & Gilmour, D. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2720 · Cited by 2,712
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
Friedl, P., & Alexander, S. (2011) · Cell · doi:10.1016/j.cell.2011.11.016 · Cited by 1,940
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Graner, F., & Glazier, J. A. (1992) · Physical Review Letters · doi:10.1103/physrevlett.69.2013 · Cited by 1,377
Physical forces during collective cell migration
Trepat, X., Wasserman, M. R., Angelini, T. E., Millet, E., Weitz, D. A., Butler, J. P., & Fredberg, J. J. (2009) · Nature Physics · doi:10.1038/nphys1269 · Cited by 1,195
Self-citationde Gennes, P. G. (1999) · Cited by 956
Collective migration of an epithelial monolayer in response to a model wound
Poujade, M., Grasland-Mongrain, E., Hertzog, A., Jouanneau, J., Chavrier, P., Ladoux, B., Buguin, A., & Silberzan, P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705062104 · Cited by 912
Collective cell guidance by cooperative intercellular forces
Tambe, D. T., Corey Hardin, C., Angelini, T. E., Rajendran, K., Park, C. Y., Serra-Picamal, X., Zhou, E. H., Zaman, M. H., Butler, J. P., Weitz, D. A., et al. (2011) · Nature Materials · doi:10.1038/nmat3025 · Cited by 884
Self-citation
Cited by
Alert, R., Casademunt, J., & Joanny, J.-F. (2022) · Annual Review of Condensed Matter Physics · doi:10.1146/annurev-conmatphys-082321-035957 · Cited by 303
Self-citationRigidity transitions in development and disease
Hannezo, E., & Heisenberg, C.-P. (2022) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.12.006 · Cited by 69
Self-assembly of tessellated tissue sheets by expansion and collision
Heinrich, M. A., Alert, R., Wolf, A. E., Košmrlj, A., & Cohen, D. J. (2022) · Nature Communications · doi:10.1038/s41467-022-31459-1 · Cited by 34
Self-citationChiral and nematic phases of flexible active filaments
Dunajova, Z., Mateu, B. P., Radler, P., Lim, K., Brandis, D., Velicky, P., Danzl, J. G., Wong, R. W., Elgeti, J., Hannezo, E., et al. (2023) · Nature Physics · doi:10.1038/s41567-023-02218-w · Cited by 23
Chiral and nematic phases of flexible active filaments
Dunajova, Z., Mateu, B. P., Radler, P., Lim, K., Velicky, P., Danzl, J. G., Wong, R. W., Elgeti, J., Hannezo, E., & Loose, M. (2022) · doi:10.1101/2022.12.15.520425 · Cited by 2
Metadata
- Authors
- Alert, R., & Trepat, X.
- Venue
- Annual Review of Condensed Matter Physics
- Publisher
- Annual Reviews
- Published
- 2020-03-10
- Volume
- 11
- Issue
- 1
- Pages
- 77-101
- ISSN
- 1947-5454 (ISSN-L)
- 1947-5462
- OpenAlex
- W2945076939
- Cited by
- 375
- References
- 144
- FWCI
- 3.98
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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