The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.
Reproduction–Immunity Trade-Offs in Insects
Open accessAbstract
Immune defense and reproduction are physiologically and energetically demanding processes and have been observed to trade off in a diversity of female insects. Increased reproductive effort results in reduced immunity, and reciprocally, infection and activation of the immune system reduce reproductive output. This trade-off can manifest at the physiological level (within an individual) and at the evolutionary level (genetic distinction among individuals in a population). The resource allocation model posits that the trade-off arises because of competition for one or more limiting resources, and we hypothesize that pleiotropic signaling mechanisms regulate allocation of that resource between reproductive and immune processes. We examine the role of juvenile hormone, 20-hydroxyecdysone, and insulin/insulin-like growth factor-like signaling in regulating both oogenesis and immune system activity, and propose a signaling network that may mechanistically regulate the trade-off. Finally, we discuss implications of the trade-off in an ecological and evolutionary context.
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Cites
The genetical theory of natural selection
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Cited by
Understanding the evolution of immune genes in jawed vertebrates
Vinkler, M., Fiddaman, S. R., Těšický, M., O'Connor, E. A., Savage, A. E., Lenz, T. L., Smith, A. L., Kaufman, J., Bolnick, D. I., Davies, C. S., et al. (2023) · Journal of Evolutionary Biology · doi:10.1111/jeb.14181 · Cited by 55
Hanson, M. A., Kondo, S., & Lemaitre, B. (2022) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2022.0773 · Cited by 31
Prigot-Maurice, C., Depeux, C., Paulhac, H., Braquart-Varnier, C., & Beltran-Bech, S. (2022) · ZooKeys · doi:10.3897/zookeys.1101.77216 · Cited by 3
Hrdina, A., & Iatsenko, I. (2026) · GENETICS · doi:10.1093/genetics/iyag058 · Cited by 2
Metadata
- Authors
- Schwenke, R. A., Lazzaro, B. P., & Wolfner, M. F.
- Venue
- Annual Review of Entomology
- Publisher
- Annual Reviews
- Published
- 2016-03-11
- Volume
- 61
- Issue
- 1
- Pages
- 239-256
- ISSN
- 0066-4170 (ISSN-L)
- 1545-4487
- OpenAlex
- W2194458678
- Cited by
- 632
- References
- 123
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
