The DOI matches its Crossref record; 167 of the 167 references it cites were found in a registry or an index.
Antigen Presentation by Extracellular Vesicles from Professional Antigen-Presenting Cells
Open accessAbstract
The initiation and maintenance of adaptive immunity require multifaceted modes of communication between different types of immune cells, including direct intercellular contact, secreted soluble signaling molecules, and extracellular vesicles (EVs). EVs can be formed as microvesicles directly pinched off from the plasma membrane or as exosomes secreted by multivesicular endosomes. Membrane receptors guide EVs to specific target cells, allowing directional transfer of specific and complex signaling cues. EVs are released by most, if not all, immune cells. Depending on the type and status of their originating cell, EVs may facilitate the initiation, expansion, maintenance, or silencing of adaptive immune responses. This review focusses on EVs from professional antigen-presenting cells, their demonstrated and speculated roles, and their potential for cancer immunotherapy.
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Cites
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Cited by
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Exosome Biochemistry and Advanced Nanotechnology for Next‐Generation Theranostic Platforms
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Plant-derived exosome-like nanoparticles and their therapeutic activities
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The function and clinical application of extracellular vesicles in innate immune regulation
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Metadata
- Authors
- Lindenbergh, M. F. S., & Stoorvogel, W.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2018-04-26
- Volume
- 36
- Issue
- 1
- Pages
- 435-459
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2785643516
- Cited by
- 373
- References
- 167
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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