The DOI matches its Crossref record; 166 of the 166 references it cites were found in a registry or an index.
Translational Control in Synaptic Plasticity and Cognitive Dysfunction
Open accessAbstract
Activity-dependent changes in the strength of synaptic connections are fundamental to the formation and maintenance of memory. The mechanisms underlying persistent changes in synaptic strength in the hippocampus, specifically long-term potentiation and depression, depend on new protein synthesis. Such changes are thought to be orchestrated by engaging the signaling pathways that regulate mRNA translation in neurons. In this review, we discuss the key regulatory pathways that govern translational control in response to synaptic activity and the mRNA populations that are specifically targeted by these pathways. The critical contribution of regulatory control over new protein synthesis to proper cognitive function is underscored by human disorders associated with either silencing or mutation of genes encoding proteins that directly regulate translation. In light of these clinical implications, we also consider the therapeutic potential of targeting dysregulated translational control to treat cognitive disorders of synaptic dysfunction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“When NMDAR activity is reduced, as with ketamine or (2R,6R)-hydroxynorketamine (2R,6R-HNK), eEF2K activity falls, eEF2 becomes dephosphorylated, and translational inhibition is rapidly lifted [141,143,145].”
From Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery (2026) · cites this paper as [143]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Translational control is a central driver of rapid synaptic plasticity, with eEF2K acting as a molecular brake on protein synthesis [141,142,143].”
From Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery (2026) · cites this paper as [143]
The cited source says what the claim attributes to it.
In the citing paper
“Neuronal protein synthesis has been well established as crucial for synaptic function and memory formation, and it is dysregulated in Alzheimer’s (43).”
From Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis (2023) · cites this paper as [43]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The synthesis of new proteins is necessary for long-term changes in synaptic plasticity and learning (132–134). In this context, learning and long-term memory formation are improved by enhanced histone acetylation (135), which could be improved by HDAC inhibitors (HDACi).”
From The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication (2020) · cites this paper as [134]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
mTOR Signaling in Growth Control and Disease
Laplante, M., & Sabatini, D. M. (2012) · Cell · doi:10.1016/j.cell.2012.03.017 · Cited by 8,509
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424
TOR signaling in growth and metabolism
Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell · doi:10.1016/j.cell.2006.01.016 · Cited by 5,787
Genome-wide atlas of gene expression in the adult mouse brain
Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature · doi:10.1038/nature05453 · Cited by 5,572
Memory - A century of consolidation
McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250
Upstream and downstream of mTOR
Hay, N., & Sonenberg, N. (2004) · Genes & Development · doi:10.1101/gad.1212704 · Cited by 4,181
Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968
The molecular biology of memory storage: a dialogue between genes and synapses
Kandel, E. R. (2001) · Science · doi:10.1126/science.1067020 · Cited by 3,917
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S., & Weissman, J. S. (2009) · Science · doi:10.1126/science.1168978 · Cited by 3,853
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
Sonenberg, N., & Hinnebusch, A. G. (2009) · Cell · doi:10.1016/j.cell.2009.01.042 · Cited by 3,304
Research works printed but not linked: 2
- Bliss TV, 1973, J. Physiol., 232, 381
- Gingras AC, 2004, Curr. Top. Microbiol. Immunol., 279, 169
Cited by
Sorted by citations
Items 201–300 of 348
Cohen, L. D., Ziv, T., & Ziv, N. E. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1038614 · Cited by 15
Feng, H., Zhang, Z., Lyu, W., Kong, X., Li, J., Zhou, H., & Wei, P. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03864-0 · Cited by 14
Regulation of filial imprinting and structural plasticity by mTORC1 in newborn chickens
Batista, G., Johnson, J. L., Dominguez, E. N., Costa‐Mattioli, M., & Peña, J. L. (2018) · Scientific Reports · doi:10.1038/s41598-018-26479-1 · Cited by 14
Self-citationProteomic Techniques to Examine Neuronal Translational Dynamics
Koren, S. A., Gillett, D. A., D’Alton, S., Hamm, M. J., & Abisambra, J. F. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143524 · Cited by 14
Human Tissues Exhibit Diverse Composition of Translation Machinery
Anisimova, A. S., Kolyupanova, N. M., Makarova, N. E., Egorov, A. A., Kulakovskiy, I. V., & Dmitriev, S. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098361 · Cited by 15
Of local translation control and lipid signaling in neurons
Moine, H., & Vitale, N. (2018) · Advances in Biological Regulation · doi:10.1016/j.jbior.2018.09.005 · Cited by 15
Farahani, M., Rezaei–Tavirani, M., Zali, A., & Azodi, M. Z. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00998-w · Cited by 13
REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment
Yi, J. H., Kwon, H., Cho, E., Jeon, J., Lee, J., Lee, Y. C., Cho, J. H., Jun, M., Moon, M., Ryu, J. H., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249482 · Cited by 14
Fan, W., Zhang, Y., Li, X., & Xu, C. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03233-0 · Cited by 13
Emerging roles for integrated stress response signaling in homeostasis
Nandakumar, S., Grmai, L., & Vasudevan, D. (2025) · FEBS Journal · doi:10.1111/febs.70166 · Cited by 14
Wang, X., Xu, M., Xu, Q., Yang, F., Tang, H., Shao, C., Wang, L., Wang, Y., Deng, J., & Wang, S. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/4947 · Cited by 12
Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
Coulson, R. L., Frattini, V., Moyer, C. E., Hodges, J., Walter, P., Mourrain, P., Zuo, Y., & Wang, G. X. (2024) · iScience · doi:10.1016/j.isci.2024.109259 · Cited by 12
Axonal RNA localization is essential for long-term memory
de Queiroz, B. R., Laghrissi, H., Rajeev, S., Blot, L., Graeve, F. D., Dehecq, M., Hallegger, M., Dag, U., de Segonzac, M. D., Ramialison, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57651-7 · Cited by 12
A Comparative Analysis of Erythropoietin and Carbamoylated Erythropoietin Proteome Profiles
Tiwari, N. K., Sathyanesan, M., Kumar, V., & Newton, S. S. (2021) · Life · doi:10.3390/life11040359 · Cited by 12
The Role of Noncoding RNAs in Neurodevelopmental Disorders: The Case of Rett Syndrome
Obiols-Guardia, A., & Guil, S. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-53889-1_2 · Cited by 12
Discrepancy Between Cerebral Structure and Cognitive Functioning
Nahm, M., Rousseau, D., & Greyson, B. (2017) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000752 · Cited by 13
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala
Yan, Y., Zhang, L., Zhu, T., Deng, S., Ma, B., Lv, H., Shan, X., Cheng, H., Jiang, K., Zhang, T., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00874-5 · Cited by 12
Sbrini, G., Brivio, P., Sangiovanni, E., Fumagalli, M., Racagni, G., Dell'Agli, M., & Calabrese, F. (2020) · Biomedicines · doi:10.3390/biomedicines8120544 · Cited by 9
Kasica, N. P., Zhou, X., Jester, H. M., Holland, C. E., Ryazanov, A. G., Forshaw, T. E., Furdui, C. M., & Ma, T. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.959326 · Cited by 12
Chmiel, J., & Malinowska, A. (2025) · Cells · doi:10.3390/cells14151152 · Cited by 14
Capsosiphon fulvescens Glycoproteins Enhance Probiotics-Induced Cognitive Improvement in Aged Rats
Oh, J. H., Nam, T., & Choi, Y. (2020) · Nutrients · doi:10.3390/nu12030837 · Cited by 11
Learning and memory in the cricket Gryllus bimaculatus
Matsumoto, Y. (2022) · Physiological Entomology · doi:10.1111/phen.12387 · Cited by 11
Development of neuronal circuits: From synaptogenesis to synapse plasticity
Cristo, G. D., & Chattopadhyaya, B. (2020) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64150-2.00005-8 · Cited by 10
LncRNAs and Chromatin Modifications Pattern m6A Methylation at the Untranslated Regions of mRNAs
Vaasjo, L. O. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.866772 · Cited by 11
The mGluR Theory of Fragile X: From Mice to Men
Stoppel, L. J., Osterweil, E. K., & Bear, M. F. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804461-2.00009-3 · Cited by 9
Madan, J. S., Gupta, K., Chattarji, S., & Bhattacharya, A. (2018) · Hippocampus · doi:10.1002/hipo.22845 · Cited by 10
Liang, R., Wang, L., Yang, Q., Xu, Q., Sun, S., Zhou, H., Zhao, M., Gao, J., Zheng, C., Yang, J., et al. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1275771 · Cited by 10
Davis, J. L., Kennedy, C., McMahon, C. L., Keegan, L., Clerkin, S., Treacy, N. J., Hoban, A. E., Kelly, Y., Brougham, D. F., Crean, J. K. G., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03315-5 · Cited by 9
Freitag, C. M., Chiocchetti, A. G., Haslinger, D., Yousaf, A., & Waltes, R. (2021) · Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie · doi:10.1024/1422-4917/a000803 · Cited by 11
Ye, R., Zhang, M., Zhang, S., Bai, S., Jiang, Z., Cai, Q., Cao, K., Shen, C., Shi, Y., Zhang, R., et al. (2020) · Journal of Integrative Neuroscience · doi:10.31083/j.jin.2020.01.1249 · Cited by 7
Shah, M.-A., Kang, J.-B., & Koh, P. (2023) · Laboratory Animal Research · doi:10.1186/s42826-023-00164-5 · Cited by 8
Translation regulation in the spinal dorsal horn – A key mechanism for development of chronic pain
Tansley, S. N., Wong, C., Uttam, S., Mogil, J. S., & Khoutorsky, A. (2018) · Neurobiology of Pain · doi:10.1016/j.ynpai.2018.03.003 · Cited by 8
Stefanik, M. T., Sakas, C., Lee, D., & Wolf, M. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.05.032 · Cited by 8
Comprehensive Genome-Wide Approaches to Activity-Dependent Translational Control in Neurons
Choe, H. K., & Cho, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051592 · Cited by 11
In-Depth Proteomic Analysis of De Novo Proteome in a Mouse Model of Alzheimer’s Disease
Wang, X., Zhou, X., Lee, J., Furdui, C. M., & Ma, T. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221044 · Cited by 7
Research progress on intestinal microbiota regulating cognitive function through the gut-brain axis
Lin, K., Peng, F., He, K., Qian, Z., Mei, X., Su, Z., Wujimaiti, Y., Xia, X., & Zhang, T. (2024) · Neurological Sciences · doi:10.1007/s10072-024-07525-5 · Cited by 8
Du, R., Wang, F., Li, L., & Wang, Q. (2025) · Obesity Reviews · doi:10.1111/obr.70048 · Cited by 9
Isaac, A. R., Chauvet, M. G., Lima‐Filho, R. A. S., Wagner, B. D. A., Caroli, B. G., Leite, R. E. P., Suemoto, C. K., Nunes, P. V., Felice, F. G. D., Ferreira, S. T., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03128-y · Cited by 6
Genomics of autism spectrum disorder: approach to therapy
Ayhan, F., & Konopka, G. (2018) · F1000Research · doi:10.12688/f1000research.13865.1 · Cited by 6
Translational control in neurovascular brain development
Chalkiadaki, K., Statoulla, E., Μάρκου, Μ., Bellou, S., Bagli, E., Fotsis, T., Murphy, C., & Gkogkas, C. G. (2021) · Royal Society Open Science · doi:10.1098/rsos.211088 · Cited by 6
Screening the Molecular Framework Underlying Local Dendritic mRNA Translation
Namjoshi, S. V., & Raab‐Graham, K. F. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00045 · Cited by 7
Benito, I., Casañas, J. J., & Montesinos, M. L. (2018) · PROTEOMICS · doi:10.1002/pmic.201800005 · Cited by 6
On the dynamical aspects of local translation at the activated synapse
Khlebodarova, T. M., Kogai, V. V., & Likhoshvai, V. A. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-03597-0 · Cited by 6
Translational Control Mechanisms in Synaptic Plasticity and Memory ☆
Costa‐Mattioli, M., & Klann, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21110-3 · Cited by 6
Self-citationPeng, Y., Huang, M., Xie, J., Shu, B., Wang, X., Liao, Y., Xu, J., & Shi, L. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15771 · Cited by 5
Synaptoneurosome Preparation from C57BL/6 Striata
Puighermanal, E., Biever, A., & Valjent, E. (2016) · BIO-PROTOCOL · doi:10.21769/bioprotoc.1735 · Cited by 5
Effects of Probiotics, Prebiotics and Synbiotic Supplementation on Cognitive Impairment: A Review
Mukilan, M. (2022) · Journal of Experimental Biology and Agricultural Sciences · doi:10.18006/2022.10(1).1.11 · Cited by 5
Luo, H., Li, W., Wu, L., Zhong, S., Du, C., Liu, Y., Xu, Y., Huang, X., Bahru, A. H., Tang, X., et al. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04853-2 · Cited by 6
Liu, Y., Ye, Q., Dai, Y., Hu, J., chen, J., Dong, J., Li, H., & Dou, Z. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150075 · Cited by 6
Li, R.-Q., Zhu, W., Li, C., Zhan, K., Zhang, P., Xiao, F., Jiang, J., & Zou, W. (2024) · Neuroscience Research · doi:10.1016/j.neures.2024.07.002 · Cited by 5
Chen, X., Ma, L., Zhao, J., Pan, X., & Chen, S. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114421 · Cited by 5
Mahadevan, V., Peltekian, A., & McBain, C. J. (2020) · Current Protocols in Neuroscience · doi:10.1002/cpns.93 · Cited by 5
Li, K., Guo, C., Wu, X., Wu, C., Wu, S., Su, S., Wu, M., Zhou, X., Li, S., Cui, Y., et al. (2025) · Advanced Science · doi:10.1002/advs.202514926 · Cited by 4
Protein Translation in Parkinson’s Disease
Kim, J. W., Abalde-Atristain, L., Jia, H., Martin, I., Dawson, T. M., & Dawson, V. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803783-6.00009-2 · Cited by 4
Strategies to Advance Drug Discovery in Rare Monogenic Intellectual Disability Syndromes
Hettige, N. C., Manzano-Vargas, K., Jefri, M., & Ernst, C. (2017) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx090 · Cited by 4
Arginine kinase interacts with 2MIT and is involved in Drosophila melanogaster short-term memory
Bozzato, A., Romoli, O., Polo, D., Baggio, F., Mazzotta, G. M., Triolo, G., Myers, M. P., & Sandrelli, F. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104118 · Cited by 4
Lee, M., Kim, E., Kim, M., & Yum, M. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03033-9 · Cited by 4
Zhai, T. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.07.043 · Cited by 5
Autism spectrum disorder: difficulties in diagnosis and microRNA biomarkers
Martinez, B., & Peplow, P. V. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00712 · Cited by 4
Epitranscriptome and FMRP Regulated mRNA Translation
Majumder, P., Chatterjee, B., & Shen, C. (2017) · Epigenomes · doi:10.3390/epigenomes1020011 · Cited by 4
Calmodulin Triggers Activity-Dependent rRNA Biogenesis via Interaction with DDX21
Yang, J., Sun, X. J., Shi, J.-X., Cui, Q.-X., Cao, X., Wang, K., An, M., Wu, S., Yang, Y.-L., Sun, H., et al. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1841-23.2024 · Cited by 4
Subcellular functions of tau mediate repair response and synaptic homeostasis in injury
Thomas, R., Zhang, D., Cronkite, C. A., Thomas, R., Singh, S. K., Bronk, L. F., Morales, R., Duman, J. G., & Grosshans, D. R. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03029-6 · Cited by 6
Alblooshi, H., AlSafar, H. S., Fisher, H., Cordell, H. J., Kashef, A. E., Ghaferi, H. A., Shawky, M., Reece, A. S., Hulse, G. K., & Tay, G. K. (2018) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32708 · Cited by 4
Chen, H., Wang, Y., Blan, A. W., Fuerte, E. P. A., Bonkowski, E. S., Bajpai, R., Pruett‐Miller, S. M., & Mefford, H. C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.25.577254 · Cited by 4
Profiling translation in the nervous system
Ichinose, T., & Tanimoto, H. (2025) · The Journal of Biochemistry · doi:10.1093/jb/mvae096 · Cited by 3
Ojha, S. K., Kartawy, M., Hamoudi, W., Tripathi, M. K., Aran, A. A., & Amal, H. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03514-6 · Cited by 4
Ilyin, N. P., Shevlyakov, A. D., Boyko, G. A., Moskalenko, A. M., Ikrin, A. N., Galstyan, D. S., Kolesnikova, T. O., Katolikova, N. V., Chekrygin, S. A., Lim, L. W., et al. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149329 · Cited by 4
Zhang, P., Yan, J., Liu, Z., Yu, H., Zhao, R. Z., & Zhou, Q. (2022) · Communications Biology · doi:10.1038/s42003-022-04018-z · Cited by 4
ERKquake in Noonan syndrome: one step closer to personalized medicine
Costa‐Mattioli, M. (2014) · Nature Neuroscience · doi:10.1038/nn.3879 · Cited by 3
Self-citationPost-transcriptional Regulation by Brain-Derived Neurotrophic Factor in the Nervous System
Amen, A. M., Pham, D. L., & Meffert, M. K. (2015) · Springer eBooks · doi:10.1007/978-3-319-25124-0_14 · Cited by 3
Chronic Pain and Cognitive Dysfunction: Clinical Implement, Mechanism, and Therapeutic Strategy
Hu, J., Gao, P.-Y., Di, R., Chen, O., & Tang, Y. (2026) · Journal of Neuroscience · doi:10.1523/jneurosci.1251-25.2026 · Cited by 3
Yadav, B., Gangwar, P., Kumari, K., Yadav, A., Rao, R., Kumar, K., Verma, H., Dhiman, M., & Mantha, A. K. (2026) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2026.1835778 · Cited by 2
Hassan, A., Iftinca, M., Young, D. W., Flynn, R. E., Agosti, F., Abdullah, N., Defaye, M., Scott, M. G. H., Dufour, A., & Altier, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052280 · Cited by 2
Zimbelman, A. R., Wong, B., Murray, C. H., Wolf, M. E., & Stefanik, M. T. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04283-w · Cited by 2
Lim, C. R., Ogawa, S., & Kumari, Y. (2024) · Archives of Pharmacal Research · doi:10.1007/s12272-024-01523-z · Cited by 2
Ehinger, Y., Laguesse, S., Phamluong, K., Salvi, A., Sei, Y. J., Hoisington, Z. W., Soneja, D., Gunasekaran, S., Nakamura, K., & Dorit Ron, A. (2025) · Nature Communications · doi:10.1038/s41467-025-60337-9 · Cited by 2
Mody, P. H., Santos, N. L. D., Lenert, M. E., Barron, L. R., Nottingham, B. A., & Burton, M. D. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.10.014 · Cited by 3
Dendritic targeted mRNA expression via a cis-acting RNA UTR element
Lu, L., Zhang, F., Li, Y., Yang, A., Guan, C., Ding, X., Liu, Y., Liu, Y., Zhang, C., Li, L., et al. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.12.137 · Cited by 2
Longo, F., Mancini, M., Ibraheem, P. L., Aryal, S., Mesini, C., Patel, J. C., Penhos, E., Rahman, N., Donohue, M., Santini, E., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.07.028241 · Cited by 2
Elder, M. K., Erdjument‐Bromage, H., Oliveira, M. M., Mamcarz, M., Neubert, T. A., & Klann, E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.21.260786 · Cited by 2
Ehinger, Y., Zhang, Z., Phamluong, K., Soneja, D., Shokat, K. M., & Dorit Ron, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.12.336701 · Cited by 2
Sex Differences In The Interaction Between Alcohol And mTORC1Preprint
Ehinger, Y., Phamluong, K., & Dorit Ron, A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.04.560781 · Cited by 2
Pathogenic tau inhibits synaptic plasticity by blocking eIF4B-mediated local protein synthesisPreprint
Kauwe, G., Lokitiyakul, D., Wong, I. L., Schneider, K., Sridhar, V., Sellegounder, D., Ngwala, Y. Y., Yao, L., Chen, J. H., Pareja-Navarro, K. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.11.675671 · Cited by 2
Role of epigenetics and alterations in RNA metabolism in leukodystrophies
Rey, F., Esposito, L., Maghraby, E., Mauri, A., Berardo, C., Bonaventura, E., Tonduti, D., Carelli, S., & Cereda, C. (2024) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1854 · Cited by 1
Hayat, D., Ogran, A., Ashkenazi, S., Plotnikov, A. N., Oren, R., Zerbib, M., Ben‐Shmuel, A., & Dikstein, R. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00449-6 · Cited by 2
The Role of Acupuncture Improving Cognitive Deficits through Regulating Neuroplasticity
Ji, S., Duan, J., Tan, M., Zhang, Y., & Chan, P. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1010850 · Cited by 1
Zhao, T., Liu, Q., Chen, J., Xie, W., Jin, Q., & Xiao, B. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.178457 · Cited by 2
Ser500 phosphorylation acts as a conformational switch to prime eEF-2K for activation
Bohanon, A. L., Browning, L. S., Piserchio, A., Long, K. J., Jacob, S., Sammons, R. M., Tavares, C. D. J., Cho, E. J., Ghose, R., & Dalby, K. N. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.111087 · Cited by 1
Cipriano, G. L., Floramo, A., Argento, V., Oddo, S., & Artimagnella, O. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010455 · Cited by 1
mRNA Translation and Proteasomal Degradation in Health and Neurological Disease
Isaac, A. R., Cozachenco, D., Wagner, B. D. A., Chauvet, M. G., & Lourenco, M. V. (2026) · Physiology · doi:10.1152/physiol.00023.2025 · Cited by 1
Genomic factors associated with substance use disorder relapse: A critical review
Al-Marzooqi, N., Al-Suhail, H., Al-Refai, M., & Alhaj, H. A. (2024) · Addictive Behaviors Reports · doi:10.1016/j.abrep.2024.100569 · Cited by 2
Abnormal Local Translation in Dendrites Impairs Cognitive Functions in Neuropsychiatric Disorders
Endo, R., Takashima, N., & Tanaka, M. (2019) · Springer eBooks · doi:10.1007/978-981-13-7908-6_18 · Cited by 1
The Integrated Stress Response in Memory and Cognitive Disorders
Mays, J., & Costa‐Mattioli, M. (2020) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190686307.013.2 · Cited by 1
Self-citationIntrahippocampal glutamine administration inhibits mTORC1 signaling and impairs long-term memoryPreprint
Rozas, N. S., Redell, J. B., Pita-Almenar, J., Mckenna, J., Moore, A., Gambello, M., & Dash, P. (2015) · Learning & memory (Cold Spring Harbor, N.Y.) · doi:10.1101/lm.038265.115 · Cited by 1
Liu, Y., Chu, J. M. T., You, R., Zhang, Y., Chang, R. C., & Wong, G. T. C. (2021) · Research Square · doi:10.21203/rs.3.rs-1010926/v1 · Cited by 1
Betancur, C., & Mitchell, K. J. (2015) · Wiley eBooks · doi:10.1002/9781118524947.ch9 · Cited by 1
Kirk, L. M., & Harris, K. M. (2016) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0000093.pub3 · Cited by 1
Hoisington, Z. W., Gangal, H., Phamluong, K., Shukla, C., Moffat, J. J., Salvi, A., Homanics, G. E., Wang, J., Ehinger, Y., & Dorit Ron, A. (2024) · eLife · doi:10.1101/2024.06.13.597459 · Cited by 1
Shetty, M. S., Kasuya, J., Fu, X., Lauffer, M. C., Tadinada, S. M., Chowdhury, T. C., Baraban, J. M., & Abel, T. G. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.10.663777 · Cited by 1
Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery
Tanaka, M. (2026) · Biomedicines · doi:10.3390/biomedicines14061265
Metadata
- Authors
- Buffington, S. A., Huang, W., & Costa-Mattioli, M.
- Affiliations
- Baylor College of Medicine (US)
- Department of Neuroscience, Memory and Brain Research Center, Baylor College of Medicine, Houston, Texas 77030;, ,
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2014-07-08
- Volume
- 37
- Issue
- 1
- Pages
- 17-38
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- PMC
- PMC4721605
- OpenAlex
- W2120053143
- Cited by
- 348
- References
- 166
- Citations by year
- 2026: 17 · 2025: 23 · 2024: 21 · 2023: 20 · 2022: 24 · 2021: 36 · 2020: 36 · 2019: 30 · 2018: 43 · 2017: 33 · 2016: 33 · 2015: 21 · 2014: 11
- FWCI
- 3.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Defense
- Searle Scholars Program
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke (R01NS076708)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- translational regulation, synaptic plasticity, long-term potentiation, long-term depression, hippocampus, mRNA translation, memory formation, cognitive impairment, synaptic dysfunction
- MeSH terms
- Animals, Cognition Disorders, Hippocampus, Humans, Models, Biological, Nerve Tissue Proteins, Neuronal Plasticity, Protein Biosynthesis, Signal Transduction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
