The DOI matches its Crossref record; 139 of the 139 references it cites were found in a registry or an index.
Environmental Exposures and Depression: Biological Mechanisms and Epidemiological Evidence
Abstract
Mental health and well-being are consistently influenced-directly or indirectly-by multiple environmental exposures. In this review, we have attempted to address some of the most common exposures of the biophysical environment, with a goal of demonstrating how those factors interact with central structures and functions of the brain and thus influence the neurobiology of depression. We emphasize biochemical mechanisms, observational evidence, and areas for future research. Finally, we include aspects of contextual environments-city living, nature, natural disasters, and climate change-and call for improved integration of environmental issues in public health science, policies, and activities. This integration is necessary for reducing the global pandemic of depression.
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“Both laboratory and naturalistic studies of parent-infant micro-interactions have documented subtle ways in which depression in a parent leads to maladaptive interactions that impede infant affect regulation and later child development and increase risk of subsequent psychopathology. 254”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [254]
Citations
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Cited by
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Time for united action on depression: a Lancet–World Psychiatric Association Commission
Herrman, H., Patel, V., Kieling, C., Berk, M., Buchweitz, C., Cuijpers, P., Furukawa, T. A., Kessler, R. C., Kohrt, B. A., Maj, M., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02141-3 · Cited by 1,104
The affective benefits of nature exposure
Bratman, G. N., Olvera‐Alvarez, H. A., & Gross, J. J. (2021) · Social and Personality Psychology Compass · doi:10.1111/spc3.12630 · Cited by 177
Depression in Alzheimer’s Disease: Epidemiology, Mechanisms, and Treatment
Huang, Y.-Y., Gan, Y.-H., Yang, L., Cheng, W., & Yu, J.-T. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.10.008 · Cited by 164
Dzhambov, A. M., Hartig, T., Tilov, B., Atanasova, V., Makakova, D. R., & Dimitrova, D. D. (2019) · Environmental Research · doi:10.1016/j.envres.2019.108708 · Cited by 144
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Bzdok, D., & Dunbar, R. I. M. (2022) · Nature Human Behaviour · doi:10.1038/s41562-022-01453-0 · Cited by 100
Metadata
- Authors
- van den Bosch, M., & Meyer-Lindenberg, A.
- Affiliations
- School of Population and Public Health; and Department of Forest and Conservation Sciences, The University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada;
- Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany;
- Venue
- Annual Review of Public Health
- Publisher
- Annual Reviews
- Published
- 2019-04-01
- Volume
- 40
- Issue
- 1
- Pages
- 239-259
- ISSN
- 0163-7525 (ISSN-L)
- 1545-2093
- OpenAlex
- W2910191925
- Cited by
- 254
- References
- 139
- Citations by year
- 2026: 26 · 2025: 36 · 2024: 46 · 2023: 39 · 2022: 38 · 2021: 40 · 2020: 20 · 2019: 9
- FWCI
- 2.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Public Health (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (156152)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Social Sciences › Urban Studies › Urban Green Space and Health
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- environmental exposure, depression, neurobiology of depression, biophysical environment, biochemical mechanisms, urban life, nature exposure, natural disasters, climate change, mental health, public health policy
- MeSH terms
- Natural Disasters, Cities, Depression, Environment, Environmental Exposure, Humans, Public Health, Mood Disorders, Climate Change
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- van den Bosch, M., & Meyer-Lindenberg, A. (2019). Environmental Exposures and Depression: Biological Mechanisms and Epidemiological Evidence. Annual Review of Public Health. https://doi.org/10.1146/annurev-publhealth-040218-044106
