Depression in Alzheimer’s Disease: Epidemiology, Mechanisms, and Treatment

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

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Social stress induces neurovascular pathology promoting depression

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The role of adult hippocampal neurogenesis in brain health and disease

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Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study

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Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

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Environmental risk factors for dementia: a systematic review

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Treating Depression in Alzheimer Disease: Efficacy and Safety of Sertraline Therapy, and the Benefits of Depression Reduction: The DIADS

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Double-blind trial of imipramine in Alzheimer's disease patients with and without depression

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Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue

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Depression in neurodegenerative diseases: Common mechanisms and current treatment options

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Prevalence of depression, anxiety, and apathy symptoms across dementia stages: A systematic review and meta‐analysis

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Environmental exposures and depression: biological mechanisms and epidemiological evidence

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Elevated Cytokine Expression in the Orbitofrontal Cortex of Victims of Suicide

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Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

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Anxiety and depression in Alzheimer’s disease: a systematic review of pathogenetic mechanisms and relation to cognitive decline

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Network beyond IDO in psychiatric disorders: Revisiting neurodegeneration hypothesis

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Management of behavioral and psychological symptoms in people with Alzheimer's disease: an international Delphi consensus

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Psychological treatments for depression and anxiety in dementia and mild cognitive impairment

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Efficacy of antidepressants for depression in Alzheimer's disease: systematic review and meta-analysis

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Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer’s Dementia in Individuals With Previous Depression

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Shared mechanisms across the major psychiatric and neurodegenerative diseases

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Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease

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Moclobemide in Elderly Patients with Cognitive Decline and Depression: An International Double-blind, Placebo-controlled Trial

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Depression, dementia and immune dysregulation

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Sertraline for the Treatment of Depression in Alzheimer Disease: Week-24 Outcomes

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A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease

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Antidepressants for treating depression in dementia

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Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target

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Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease

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Transcranial magnetic stimulation and transcranial direct current stimulation: treatments for cognitive and neuropsychiatric symptoms in the neurodegenerative dementias?

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Adult hippocampal neurogenesis in Alzheimer’s disease: A roadmap to clinical relevance

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Association between vascular endothelial growth factor-mediated blood-brain barrier dysfunction and stress-induced depression

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A Double-Blind, Randomized, Fixed-Dose Trial of Fluoxetine vs. Amitriptyline in the Treatment of Major Depression Complicating Alzheimer's Disease

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Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis

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Risk of Dementia in persons who have previously experienced clinically-significant Depression, Anxiety, or PTSD: A Systematic Review and Meta-Analysis

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Depression and Antidepressants as Potential Risk Factors in Dementia: A Systematic Review and Meta-analysis of 18 Longitudinal Studies

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(2022) · doi:10.1016/j.biopsych.2022.08.026 · Cited by 113 · see citing works

Meta-Analysis of the Prevalence of Major Depressive Disorder Among Older Adults With Dementia

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Efficacy and tolerability of antidepressants in people aged 65 years or older with major depressive disorder – A systematic review and a meta-analysis

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Depression is Associated with Tau and Not Amyloid Positron Emission Tomography in Cognitively Normal Adults

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Psychological treatments for depression and anxiety in dementia and mild cognitive impairment

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The association of depression with subsequent dementia diagnosis: A Swedish nationwide cohort study from 1964 to 2016

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Associations between depression and cognition, mild cognitive impairment and dementia in persons with diabetes mellitus: A systematic review and meta-analysis

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Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ1–40) administration in mice

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Amyloid-beta and depression in healthy older adults: A systematic review

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Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer’s disease

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The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer’s Disease: A Preclinical Study in APP/PS1 Transgenic Mice

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Depression in Alzheimer's Disease: A Delphi Consensus on Etiology, Risk Factors, and Clinical Management

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No Association of Lower Hippocampal Volume With Alzheimer’s Disease Pathology in Late-Life Depression

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Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer’s Disease Neuroimaging Initiative Depression Project

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Genetic Evidence Supporting a Causal Role of Depression in Alzheimer’s Disease

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Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder

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Development of Apathy, Anxiety, and Depression in Cognitively Unimpaired Older Adults: Effects of Alzheimer’s Disease Pathology and Cognitive Decline

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Systematic review and meta-analysis of second-generation antidepressants for the treatment of older adults with depression: questionable benefit and considerations for frailty

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Depression Case Finding in Individuals with Dementia: A Systematic Review and Meta‐Analysis

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Exposure to Antidepressant Medication and the Risk of Incident Dementia

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Comparison of Sertraline, Venlafaxine and Desipramine Effects on Depression, Cognition and the Daily Living Activities in Alzheimer Patients

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Effect of escitalopram on Aβ levels and plaque load in an Alzheimer mouse model

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The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer’s Disease

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Late-life depression and the risk of dementia in 14 countries: a 10-year follow-up study from the Survey of Health, Ageing and Retirement in Europe

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Association of life‐course depression with the risk of dementia in late life: A nationwide twin study

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Treatment Effects of Vortioxetine on Cognitive Functions in Mild Alzheimer's Disease Patients with Depressive Symptoms: A 12 Month, Open-Label, Observational Study

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