The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Exceptionally Stable Nucleic Acid Hairpins
Abstract
Hairpins represent the dominant secondary structure element in RNA. Certain sequences are found with exceptional frequency in many RNAs and are characterized by exceptionally high thermodynamic stability. Stable RNA hairpins define nucleation sites for folding, determine tertiary interactions in RNA enzymes, protect mRNAs from degradation, and are recognized by RNA-binding proteins. The structures of several stable DNA and RNA hairpins have revealed networks of stabilizing interactions within the hairpin loop: non-Watson-Crick base pairs and base-phosphate and base-sugar contacts. The unusual stability of these structural elements can be used to stabilize RNA and DNA structures and to protect antisense oligonucleotides and mRNAs against exonucleolytic degradation.
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Cites
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Improved predictions of secondary structures for RNA.
Jaeger, J. A., Turner, D. H., & Zuker, M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.20.7706 · Cited by 817
Structural Features that Give Rise to the Unusual Stability of RNA Hairpins Containing GNRA Loops
Heus, H. A., & Pardi, A. (1991) · Science · doi:10.1126/science.1712983 · Cited by 620
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA
Moazed, D., Robertson, J. M., & Noller, H. F. (1988) · Nature · doi:10.1038/334362a0 · Cited by 483
Skripkin, E., Paillart, J. C., Marquet, R., Ehresmann, B., & Ehresmann, C. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.11.4945 · Cited by 401
Structure of an unusually stable RNA hairpin
Varani, G., Cheong, C., & Tinoco, I. (1991) · Biochemistry · doi:10.1021/bi00227a016 · Cited by 369
Self-citationCrystal structure of an RNA double helix incorporating a track of non-Watson–Crick base pairs
Holbrook, S. R., Cheong, C., Tinoco, I., & Kim, S.-H. (1991) · Nature · doi:10.1038/353579a0 · Cited by 306
A thermodynamic study of unusually stable RNA and DNA hairpins
Antao, V. P., Lai, S. Y., & Tinoco, I. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.21.5901 · Cited by 296
Pley, H. W., Flaherty, K. M., & McKay, D. B. (1994) · Nature · doi:10.1038/372111a0 · Cited by 274
GAAA Tetraloop and Conserved Bulge Stabilize Tertiary Structure of a Group I Intron Domain
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Cited by
The Thermodynamics of DNA Structural Motifs
SantaLucia, J., & Hicks, D. (2004) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.32.110601.141800 · Cited by 1,314
Woodside, M. T., Behnke-Parks, W. M., Larizadeh, K., Travers, K., Herschlag, D., & Block, S. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511048103 · Cited by 474
Denning, E. J., Priyakumar, U. D., Nilsson, L., & Mackerell, A. D. (2011) · Journal of Computational Chemistry · doi:10.1002/jcc.21777 · Cited by 405
Banáš, P., Hollas, D., Zgarbová, M., Jurečka, P., Orozco, M., Cheatham, T. E., Šponer, J., & Otyepka, M. (2010) · Journal of Chemical Theory and Computation · doi:10.1021/ct100481h · Cited by 373
RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence
Masliah, G., Barraud, P., & Allain, F. H. T. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1119-x · Cited by 259
Metadata
- Authors
- Varani, G.
- Venue
- Annual Review of Biophysics and Biomolecular Structure
- Publisher
- Annual Reviews
- Published
- 1995-06
- Volume
- 24
- Issue
- 1
- Pages
- 379-404
- ISSN
- 1056-8700 (ISSN-L)
- 1545-4266
- OpenAlex
- W2032930812
- Cited by
- 306
- References
- 22
- FWCI
- 3.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- Varani, G. (1995). Exceptionally Stable Nucleic Acid Hairpins. Annual Review of Biophysics and Biomolecular Structure. https://doi.org/10.1146/annurev.bb.24.060195.002115
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
