The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
De Novo Design and Structural Characterization of Proteins and Metalloproteins
Abstract
▪ Abstract De novo protein design has recently emerged as an attractive approach for studying the structure and function of proteins. This approach critically tests our understanding of the principles of protein folding; only in de novo design must one truly confront the issue of how to specify a protein's fold and function. If we truly understand proteins, it should be possible to design receptors, enzymes, and ion channels from scratch. Further, as this understanding evolves and is further refined, it should be possible to design proteins and biomimetic polymers with properties unprecedented in nature.
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Cites
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Cited by
Protein Design: Toward Functional Metalloenzymes
Yu, F., Cangelosi, V. M., Zastrow, M. L., Tegoni, M., Plegaria, J. S., Tebo, A. G., Mocny, C. S., Ruckthong, L., Qayyum, H., & Pecoraro, V. L. (2014) · Chemical Reviews · doi:10.1021/cr400458x · Cited by 441
Hydrolytic catalysis and structural stabilization in a designed metalloprotein
Zastrow, M. L., Peacock, A. F. A., Stuckey, J. A., & Pecoraro, V. L. (2012) · Nature Chemistry · doi:10.1038/nchem.1201 · Cited by 355
Random heteropolymers preserve protein function in foreign environments
Panganiban, B., Qiao, B., Jiang, T., DelRe, C., Obadia, M. M., Nguyen, T. D., Smith, A. A. A., Hall, A., Sit, I., Crosby, M. G., et al. (2018) · Science · doi:10.1126/science.aao0335 · Cited by 294
Proteins evolve on the edge of supramolecular self-assembly
Garcia-Seisdedos, H., Empereur-Mot, C., Elad, N., & Levy, E. D. (2017) · Nature · doi:10.1038/nature23320 · Cited by 253
Design of a Selective Metal Ion Switch for Self-Assembly of Peptide-Based Fibrils
Dublin, S. N., & Conticello, V. P. (2008) · Journal of the American Chemical Society · doi:10.1021/ja0775016 · Cited by 156
Metadata
- Authors
- DeGrado, W. F., Summa, C. M., Pavone, V., Nastri, F., & Lombardi, A.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 1999-06
- Volume
- 68
- Issue
- 1
- Pages
- 779-819
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2104460080
- Cited by
- 572
- References
- 12
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: De Novo Design and Structural Characterization of Proteins and Metalloproteins. https://app.cochat.ai/papers/10.1146/annurev.biochem.68.1.779
- The paper
- DeGrado, W. F., Summa, C. M., Pavone, V., Nastri, F., & Lombardi, A. (1999). De Novo Design and Structural Characterization of Proteins and Metalloproteins. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.68.1.779
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
