The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Aminoacyl-tRNA Synthesis
Abstract
▪ Abstract Aminoacyl-tRNAs are substrates for translation and are pivotal in determining how the genetic code is interpreted as amino acids. The function of aminoacyl-tRNA synthesis is to precisely match amino acids with tRNAs containing the corresponding anticodon. This is primarily achieved by the direct attachment of an amino acid to the corresponding tRNA by an aminoacyl-tRNA synthetase, although intrinsic proofreading and extrinsic editing are also essential in several cases. Recent studies of aminoacyl-tRNA synthesis, mainly prompted by the advent of whole genome sequencing and the availability of a vast body of structural data, have led to an expanded and more detailed picture of how aminoacyl-tRNAs are synthesized. This article reviews current knowledge of the biochemical, structural, and evolutionary facets of aminoacyl-tRNA synthesis.
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Cites
Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
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Cited by
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Nutrient-sensing mechanisms and pathways
Efeyan, A., Comb, W. C., & Sabatini, D. M. (2015) · Nature · doi:10.1038/nature14190 · Cited by 1,110
Aminoacyl-tRNA Synthetases, the Genetic Code, and the Evolutionary Process
Woese, C. R., Olsen, G. J., Ibba, M., & Söll, D. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.1.202-236.2000 · Cited by 706
Self-citationNatural expansion of the genetic code
Ambrogelly, A., Palioura, S., & Söll, D. (2007) · Nature Chemical Biology · doi:10.1038/nchembio847 · Cited by 361
Self-citationSelective Charging of tRNA Isoacceptors Explains Patterns of Codon Usage
Elf, J., Nilsson, D., Tenson, T., & Ehrenberg, M. (2003) · Science · doi:10.1126/science.1083811 · Cited by 260
Metadata
- Authors
- Ibba, M., & Söll, D.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2000-06
- Volume
- 69
- Issue
- 1
- Pages
- 617-650
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2140885472
- Cited by
- 1,459
- References
- 4
- FWCI
- 2.43
- Type
- journal article
- Language
- en
- Open access
- closed
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