DNA Polymerase γ, The Mitochondrial Replicase

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MITOCHONDRIAL DNA MAINTENANCE IN VERTEBRATES

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Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ

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TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA

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The initiation of mitochondrial DNA replication

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Motif WFYY of human PrimPol is crucial to stabilize the incoming 3′-nucleotide during replication fork restart

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Physical and Functional Interaction of Mitochondrial Single-Stranded DNA-Binding Protein and the Catalytic Subunit of DNA Polymerase Gamma

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Effect of Oxidative Stress on DNA Repairing Genes

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Mechanisms for High Fidelity DNA Replication

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Atomistic Molecular Dynamics Simulations of Mitochondrial DNA Polymerase γ: Novel Mechanisms of Function and Pathogenesis

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Biological and translational attributes of mitochondrial DNA copy number: Laboratory perspective to clinical relevance

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A Scoping Review of POLG-Related Cerebellar Ataxia: Insights and Clinical Perspectives

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Autophagy‐independent mitochondrial quality control: Mechanisms and disease associations

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Mitochondrial DNA Enrichment for Sensitive Next-Generation Sequencing

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mtDNA extramitochondrial replication mediates mitochondrial defect effects

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Copy number variations of the mitochondrial DNA as potential cause of mitochondrial diseases

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The evolution of mitochondrial genome structure and function in insects

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DNA Base Excision Repair: A Recipe for Survival

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Analysis of enzyme kinetic data for mtDNA replication

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A mitochondrial implication in a Tunisian patient with Friedreich's ataxia-like

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Measurement of kinetic parameters of human platelet DNA polymerase γ

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Mitochondrial Biogenesis and Quality Control

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The Role p53 Protein in DNA Repair

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Effects of Parkin on the Mitochondrial Genome in the Heart and Brain of Mitochondrial Mutator Mice

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Description of muscle disease – specific diseases

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PCNA and Rnh1 independently participate in the protection of mitochondrial genome against UV-induced mutagenesis in yeast cells

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Flow Cytometric Quantification of Mitochondrial Properties: A High-Throughput Approach for Single Organelle Analysis

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Elevated mtDNA copy number in older adults is linked to methylation of mitochondrial and nuclear regulatory regions

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Irradiated Liver Cancer Cell Vaccine Transfected With GM ‐ CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM ‐ CSF

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Coupled aggregation of mitochondrial single-strand DNA-binding protein tagged with Eos fluorescent protein visualizes synchronized activity of mitochondrial nucleoids

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El espectro clínico de las mutaciones en POLG

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Mitochondrial DNA in neurons and its modulation by neurotoxins

Santos, M. S. (2006) · D-Scholarship@Pitt (University of Pittsburgh) · Cited by 1

Mitochondrial DNA variation in extremely selected traits: longevity and elite athletic performance

Niemi, A. (2005) · Cited by 1

Mitochondrial DNA Replication

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The Consequences of Damaged Mitochondrial DNA

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Genes Involved in DNA Repair and Mitophagy Protect Embryoid Bodies from the Toxic Effect of Methylmercury Chloride under Physioxia Conditions

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Methionine Restriction Differentially Modulates Expression of Genes in the Base Excision Repair Pathway in Rat Brain and Liver

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Oxidative Damage and Repair in the Mitochondrial Genome

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Resource Letter: Bio-molecular Nano-machines: where Physics, Chemistry, Biology and Technology meetPreprint

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R-Loop control and mitochondria genome stability require the 5’-3’ exonuclease/flap endonuclease OEX1Preprint

Schatz-Daas, D., Blevenec, A. L., Moratti, F. G., Chung, K. P., Mercier, P., Iqbal, R. K., Vallet, E., Dietrich, A., Bock, R., Weber‐Lotfi, F., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.05.621957 · Cited by 1

LONP-1 deficiency causes dysregulated protein synthesis within mitochondria that is restored by mitoribosomal mutationsPreprint

Ali, L., Mallick, A., Du, Y., Li, R., Zhu, L. J., Shen, K., & Haynes, C. M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.14.699555 · Cited by 1

Mitochondrial DNA and RNA Polymerases

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The effects of mitochondrial DNA mutagenesis on somatic stem cells and ageing

Ahlqvist, K. J. (2015) · Työväentutkimus Vuosikirja

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Anvret, A. (2011) · Figshare

Mitochondrial DNA haplogroup-dependence of drugs and xenobiotics toxicity

Strobbe, D. (2014) · Padua@research (University of Padova)

Molecular mechanisms of mitochondrial DNA replication

Holmlund, T. (2009) · Figshare

The impact of mitochondria on preimplantation development in the rhesus macaque

Gibson, T. C. (2010) · Human Biology

Functional and structural characterization of the human mitochondrial helicase

Korhonen, J. A. (2007) · Figshare

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Ross, J. M. (2012) · Figshare

Molecular insights into mitochondrial dna replication

Fusté, J. M. (2012) · Figshare

MOLECULAR MECHANISMS OF MAMMALIAN MITOCHONDRIAL DNA REPLICATION AND TRANSCRIPTION

Pellegrini, M. (2009) · Figshare

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Transgenic mouse models of HIV-1/AIDS and cardiac performance

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Investigating markers of cellular aging in Human Immunodeficiency Virus infected and uninfected adults

Zanet, D. L. (2013) · cIRcle (University of British Columbia) · doi:10.14288/1.0165594

SCREENING MUTAZIONALE DI GENI IMPLICATI IN VARIE FORME DI ATASSIE RECESSIVE

Dottorato, T. D. (2007)

mitochondrial genome interaction POLG-related disorders : Defects of the nuclear and

Milone, M., Benarroch, E. E., & Wong, L. (2011)

Stochastic modeling of mitochondrial polymerase gamma replication and novel algorithms to enrich rare disease alleles and detect tumor somatic mutations in deep sequencing data

Song, Z. (2012)

Mitochondria Remodeling in Cancer

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